Impaired Wnt Signaling in the Prefrontal Cortex of Alzheimer’s Disease

Wnt3a ligand facilitates autophagy in hippocampal neurons by modulating a novel GSK-3β-AMPK axis

(2018) Juvenal A. Ríos et al.   Cell Communication and Signaling

Wnt signaling loss accelerates the appearance of neuropathological hallmarks of Alzheimer's disease in J20-APP transgenic and wild-type mice

(2018) Cheril Tapia-Rojas et al.   JOURNAL OF NEUROCHEMISTRY

GSK3 in Alzheimer's Disease: Mind the Isoforms

(2018) Tao Ma   JOURNAL OF ALZHEIMERS DISEASE

Altered Distribution of RhoA in Alzheimer's Disease and AβPP Overexpressing Mice

(2017) Gema Huesa et al.   JOURNAL OF ALZHEIMERS DISEASE

The genetics of bone mass and susceptibility to bone diseases

(2016) David Karasik et al.   Nature Reviews Rheumatology

Alzheimer Disease: Crosstalk between the Canonical Wnt/Beta-Catenin Pathway and PPARs Alpha and Gamma

(2016) Alexandre Vallée et al.   Frontiers in Neuroscience

Assessment of brain reference genes for RT-qPCR studies in neurodegenerative diseases

(2016) Rasmus Rydbirk et al.   Scientific Reports

Activation of the Wnt/β-catenin pathway represses the transcription of the β-amyloid precursor protein cleaving enzyme (BACE1) via binding of T-cell factor-4 to BACE1 promoter

(2015) Callum Parr et al.   FASEB JOURNAL

Aberrant Wnt signaling pathway in medial temporal lobe structures of Alzheimer’s disease

(2015) Jesper Riise et al.   JOURNAL OF NEURAL TRANSMISSION

Wnt co-receptor LRP5/6 overexpression confers protection against hydrogen peroxide-induced neurotoxicity and reduces tau phosphorylation in SH-SY5Y cells

(2015) Luqi Zhang et al.   NEUROCHEMISTRY INTERNATIONAL

Effects of Age and Estrogen on Skeletal Gene Expression in Humans as Assessed by RNA Sequencing

(2015) Joshua N. Farr et al.   PLoS One

Deficiency in LRP6-Mediated Wnt Signaling Contributes to Synaptic Abnormalities and Amyloid Pathology in Alzheimer’s Disease

(2014) Chia-Chen Liu et al.   NEURON

Wnt signaling in the nervous system and in Alzheimer's disease

(2014) N. C. Inestrosa et al.   Journal of Molecular Cell Biology

The Design of a Quantitative Western Blot Experiment

(2014) Sean C. Taylor et al.   Biomed Research International

The regulation and deregulation of Wnt signaling by PARK genes in health and disease

(2013) D. C. Berwick et al.   Journal of Molecular Cell Biology

Epidemiology of Alzheimer Disease

(2013) R. Mayeux et al.   Cold Spring Harbor Perspectives in Medicine

Phosphorylation of β-catenin at serine 663 regulates its transcriptional activity

(2012) Mee-Hee Park et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Secreted Wnt Antagonist Dickkopf-1 Is Required for Amyloid  -Mediated Synaptic Loss

(2012) S. A. Purro et al.   JOURNAL OF NEUROSCIENCE

Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt–PCP–JNK pathway

(2012) R Killick et al.   MOLECULAR PSYCHIATRY

A novel functional low-density lipoprotein receptor-related protein 6 gene alternative splice variant is associated with Alzheimer's disease

(2012) Marcelo A. Alarcón et al.   NEUROBIOLOGY OF AGING

Disease-modifying properties of long-term lithium treatment for amnestic mild cognitive impairment: randomised controlled trial

(2011) Orestes V. Forlenza et al.   BRITISH JOURNAL OF PSYCHIATRY

Wnt signaling during synaptic development and plasticity

(2011) Vivian Budnik et al.   CURRENT OPINION IN NEUROBIOLOGY

Curcumin activates Wnt/β-catenin signaling pathway through inhibiting the activity of GSK-3β in APPswe transfected SY5Y cells

(2011) Xiong Zhang et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Temporal dynamics and genetic control of transcription in the human prefrontal cortex

(2011) Carlo Colantuoni et al.   NATURE

Molecular Insights into the Pathogenesis of Alzheimer's Disease and Its Relationship to Normal Aging

(2011) Alexei A. Podtelezhnikov et al.   PLoS One

The Wnt/beta-catenin pathway is activated during advanced arterial aging in humans

(2010) Alexandre Marchand et al.   AGING CELL

The MIQE Guidelines: Minimum Information for Publication of Quantitative Real-Time PCR Experiments

(2009) S. A. Bustin et al.   CLINICAL CHEMISTRY

Different Rho GTPase–dependent signaling pathways initiate sequential steps in the consolidation of long-term potentiation

(2009) Christopher S. Rex et al.   JOURNAL OF CELL BIOLOGY

Dkk-3 is elevated in CSF and plasma of Alzheimer’s disease patients

(2009) Christoph Zenzmaier et al.   JOURNAL OF NEUROCHEMISTRY

Increased Dickkopf-1 expression in transgenic mouse models of neurodegenerative disease

(2009) Maria Cristina Rosi et al.   JOURNAL OF NEUROCHEMISTRY

Dentate gyrus-specific knockdown of adult neurogenesis impairs spatial and object recognition memory in adult rats

(2009) S. Jessberger et al.   LEARNING & MEMORY

Alzheimer's disease: synaptic dysfunction and Aβ

(2009) Ganesh M Shankar et al.   Molecular Neurodegeneration

Activation of Wnt signaling by lithium and rosiglitazone reduced spatial memory impairment and neurodegeneration in brains of an APPswe/PSEN1ΔE9 mouse model of Alzheimer's disease

(2009) E M Toledo et al.   MOLECULAR PSYCHIATRY

Tau-knockout mice show reduced GSK3-induced hippocampal degeneration and learning deficits

(2009) Elena Gómez de Barreda et al.   NEUROBIOLOGY OF DISEASE

Neuropsychology of prefrontal cortex

(2009) Nishant Goyal et al.   Indian Journal of Psychiatry

Wnts acting through canonical and noncanonical signaling pathways exert opposite effects on hippocampal synapse formation

(2008) Elizabeth K Davis et al.   Neural Development

Altered neuronal gene expression in brain regions differentially affected by Alzheimer's disease: a reference data set

(2008) Winnie S. Liang et al.   PHYSIOLOGICAL GENOMICS