The cell biology of planar cell polarity

The Balance of Prickle/Spiny-Legs Isoforms Controls the Amount of Coupling between Core and Fat PCP Systems

(2014) Matthias Merkel et al.   CURRENT BIOLOGY

Prickle/spiny-legs isoforms control the polarity of the apical microtubule network in planar cell polarity

(2014) Jessica Olofsson et al.   DEVELOPMENT

PCP and Septins Compartmentalize Cortical Actomyosin to Direct Collective Cell Movement

(2014) A. Shindo et al.   SCIENCE

Dachsous-Dependent Asymmetric Localization of Spiny-Legs Determines Planar Cell Polarity Orientation in Drosophila

(2014) Tomonori Ayukawa et al.   Cell Reports

Microtubules provide directional information for core PCP function

(2014) Maja Matis et al.   eLife

A Cul-3-BTB ubiquitylation pathway regulates junctional levels and asymmetry of core planar polarity proteins

(2013) H. Strutt et al.   DEVELOPMENT

A Molecular Blueprint at the Apical Surface Establishes Planar Asymmetry in Cochlear Hair Cells

(2013) Basile Tarchini et al.   DEVELOPMENTAL CELL

Regulation of PCP by the Fat signaling pathway

(2013) M. Matis et al.   GENES & DEVELOPMENT

Postnatal Refinement of Auditory Hair Cell Planar Polarity Deficits Occurs in the Absence of Vangl2

(2013) C. O. Copley et al.   JOURNAL OF NEUROSCIENCE

Wg and Wnt4 provide long-range directional input to planar cell polarity orientation in Drosophila

(2013) Jun Wu et al.   NATURE CELL BIOLOGY

Primary cilium migration depends on G-protein signalling control of subapical cytoskeleton

(2013) Jerome Ezan et al.   NATURE CELL BIOLOGY

Strabismus Promotes Recruitment and Degradation of Farnesylated Prickle in Drosophila melanogaster Planar Polarity Specification

(2013) Helen Strutt et al.   PLoS Genetics

A novel GTP-binding protein–adaptor protein complex responsible for export of Vangl2 from the trans Golgi network

(2013) Yusong Guo et al.   eLife

Planar Cell Polarity Links Axes of Spatial Dynamics in Neural-Tube Closure

(2012) Tamako Nishimura et al.   CELL

Planar Polarity Specification through Asymmetric Subcellular Localization of Fat and Dachsous

(2012) Amy Brittle et al.   CURRENT BIOLOGY

Microtubules Enable the Planar Cell Polarity of Airway Cilia

(2012) Eszter K. Vladar et al.   CURRENT BIOLOGY

Propagation of Dachsous-Fat Planar Cell Polarity

(2012) Abhijit A. Ambegaonkar et al.   CURRENT BIOLOGY

Establishment of Global Patterns of Planar Polarity during Growth of the Drosophila Wing Epithelium

(2012) Andreas Sagner et al.   CURRENT BIOLOGY

Dissecting the molecular bridges that mediate the function of Frizzled in planar cell polarity

(2012) G. Struhl et al.   DEVELOPMENT

DrosophilaCK1-γ,gilgamesh, controls PCP-mediated morphogenesis through regulation of vesicle trafficking

(2012) William J. Gault et al.   JOURNAL OF CELL BIOLOGY

Mechanical Control of Morphogenesis by Fat/Dachsous/Four-Jointed Planar Cell Polarity Pathway

(2012) F. Bosveld et al.   SCIENCE

Principles of planar polarity in animal development

(2011) L. V. Goodrich et al.   DEVELOPMENT

Wnt/PCP signaling controls intracellular position of MTOCs during gastrulation convergence and extension movements

(2011) D. S. Sepich et al.   DEVELOPMENT

Dynamics of Core Planar Polarity Protein Turnover and Stable Assembly into Discrete Membrane Subdomains

(2011) Helen Strutt et al.   DEVELOPMENTAL CELL

Wnt Signaling Gradients Establish Planar Cell Polarity by Inducing Vangl2 Phosphorylation through Ror2

(2011) Bo Gao et al.   DEVELOPMENTAL CELL

The roles of the cadherins Fat and Dachsous in planar polarity specification inDrosophila

(2011) Chloe Thomas et al.   DEVELOPMENTAL DYNAMICS

Planar polarization of the atypical myosin Dachs orients cell divisions in Drosophila

(2011) Y. Mao et al.   GENES & DEVELOPMENT

Mitotic internalization of planar cell polarity proteins preserves tissue polarity

(2011) Danelle Devenport et al.   NATURE CELL BIOLOGY

Cell Flow Reorients the Axis of Planar Polarity in the Wing Epithelium of Drosophila

(2010) Benoît Aigouy et al.   CELL

Four-Jointed Modulates Growth and Planar Polarity by Reducing the Affinity of Dachsous for Fat

(2010) Amy L. Brittle et al.   CURRENT BIOLOGY

Modulation of Fat:Dachsous Binding by the Cadherin Domain Kinase Four-Jointed

(2010) Michael A. Simon et al.   CURRENT BIOLOGY

The Fz-Dsh Planar Cell Polarity Pathway Induces Oriented Cell Division via Mud/NuMA in Drosophila and Zebrafish

(2010) Marion Ségalen et al.   DEVELOPMENTAL CELL

Atypical Cadherins Dachsous and Fat Control Dynamics of Noncentrosomal Microtubules in Planar Cell Polarity

(2010) Toshiyuki Harumoto et al.   DEVELOPMENTAL CELL

The PCP genes Celsr1 and Vangl2 are required for normal lung branching morphogenesis

(2010) Laura L. Yates et al.   HUMAN MOLECULAR GENETICS

Planar cell polarity breaks bilateral symmetry by controlling ciliary positioning

(2010) Hai Song et al.   NATURE

Vangl2 directs the posterior tilting and asymmetric localization of motile primary cilia

(2010) Antonia Borovina et al.   NATURE CELL BIOLOGY

Planar polarization of node cells determines the rotational axis of node cilia

(2010) Masakazu Hashimoto et al.   NATURE CELL BIOLOGY

Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus

(2010) Fadel Tissir et al.   NATURE NEUROSCIENCE

Planar Cell Polarity Enables Posterior Localization of Nodal Cilia and Left-Right Axis Determination during Mouse and Xenopus Embryogenesis

(2010) Dragana Antic et al.   PLoS One

Planar Cell Polarity Acts Through Septins to Control Collective Cell Movement and Ciliogenesis

(2010) Su Kyoung Kim et al.   SCIENCE

Regulation of Planar Cell Polarity by Smurf Ubiquitin Ligases

(2009) Masahiro Narimatsu et al.   CELL

Rho1 has multiple functions in Drosophila wing planar polarity

(2009) Jie Yan et al.   DEVELOPMENTAL BIOLOGY

Asymmetric localisation of planar polarity proteins: Mechanisms and consequences

(2009) Helen Strutt et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Asymmetric Homotypic Interactions of the Atypical Cadherin Flamingo Mediate Intercellular Polarity Signaling

(2008) Wei-Shen Chen et al.   CELL

Differential Stability of Flamingo Protein Complexes Underlies the Establishment of Planar Polarity

(2008) Helen Strutt et al.   CURRENT BIOLOGY

Planar polarity genes in the Drosophila wing regulate the localisation of the FH3-domain protein Multiple Wing Hairs to control the site of hair production

(2008) D. Strutt et al.   DEVELOPMENT

The Frizzled Extracellular Domain Is a Ligand for Van Gogh/Stbm during Nonautonomous Planar Cell Polarity Signaling

(2008) Jun Wu et al.   DEVELOPMENTAL CELL

The multiple-wing-hairs Gene Encodes a Novel GBD-FH3 Domain-Containing Protein That Functions Both Prior to and After Wing Hair Initiation

(2008) J. Yan et al.   GENETICS

Cooperation of polarized cell intercalations drives convergence and extension of presomitic mesoderm during zebrafish gastrulation

(2008) Chunyue Yin et al.   JOURNAL OF CELL BIOLOGY

Planar polarization in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles

(2008) Danelle Devenport et al.   NATURE CELL BIOLOGY

Four-jointed Is a Golgi Kinase That Phosphorylates a Subset of Cadherin Domains

(2008) H. O. Ishikawa et al.   SCIENCE