Evaluation of the NLRP3 Inflammasome Activating Effects of a Large Panel of TiO2 Nanomaterials in Macrophages

Metabolomics profiling to investigate nanomaterial toxicity in vitro and in vivo

(2020) Anne Bannuscher et al.   Nanotoxicology

The protein corona suppresses the cytotoxic and pro-inflammatory response in lung epithelial cells and macrophages upon exposure to nanosilica

(2019) Regina Leibe et al.   ARCHIVES OF TOXICOLOGY

Comparison of the effects of multiwall carbon nanotubes on the epithelial cells and macrophages

(2019) Masanori Horie et al.   Nanotoxicology

Self-defense of macrophages against oxidative injury: Fighting for their own survival

(2019) László Virág et al.   Redox Biology

Length-dependent toxicity of TiO2 nanofibers: mitigation via shortening

(2019) Massimiliano G. Bianchi et al.   Nanotoxicology

Critical review of the safety assessment of titanium dioxide additives in food

(2018) Hans Christian Winkler et al.   JOURNAL OF NANOBIOTECHNOLOGY

Pro-inflammatory adjuvant properties of pigment-grade titanium dioxide particles are augmented by a genotype that potentiates interleukin 1β processing

(2017) Sebastian Riedle et al.   Particle and Fibre Toxicology

SiO2 and TiO2 nanoparticles synergistically trigger macrophage inflammatory responses

(2017) Misato Tsugita et al.   Particle and Fibre Toxicology

Phagolysosome acidification is required for silica and engineered nanoparticle-induced lysosome membrane permeabilization and resultant NLRP3 inflammasome activity

(2017) Forrest Jessop et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Impact of serum as a dispersion agent for in vitro and in vivo toxicological assessments of TiO2 nanoparticles

(2016) Sandra Vranic et al.   ARCHIVES OF TOXICOLOGY

Titanium dioxide nanoparticles exacerbate DSS-induced colitis: role of the NLRP3 inflammasome

(2016) Pedro A Ruiz et al.   GUT

A Multilaboratory Toxicological Assessment of a Panel of 10 Engineered Nanomaterials to Human Health—ENPRA Project—The Highlights, Limitations, and Current and Future Challenges

(2016) Ali Kermanizadeh et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS

Oxidant generation, DNA damage and cytotoxicity by a panel of engineered nanomaterials in three different human epithelial cell lines

(2016) Waluree Thongkam et al.   MUTAGENESIS

Shape engineered TiO2 nanoparticles in Caenorhabditis elegans: a Raman imaging based approach to assist tissue-specific toxicological studies

(2016) Luca Iannarelli et al.   RSC Advances

An in vitro alveolar macrophage assay for predicting the short-term inhalation toxicity of nanomaterials

(2016) Martin Wiemann et al.   JOURNAL OF NANOBIOTECHNOLOGY

The complex cascade of cellular events governing inflammasome activation and IL-1β processing in response to inhaled particles

(2015) Virginie Rabolli et al.   Particle and Fibre Toxicology

The NLRP3 inflammasome is activated by nanoparticles through ATP, ADP and adenosine

(2015) L Baron et al.   Cell Death & Disease

A comparative study on the efficacy of different probes to predict the photo-activity of nano-titanium dioxide toward biomolecules

(2015) A. Marucco et al.   RSC Advances

The alarmin IL-1α is a master cytokine in acute lung inflammation induced by silica micro- and nanoparticles

(2014) Virginie Rabolli et al.   Particle and Fibre Toxicology

Silica-induced NLRP3 inflammasome activation in vitro and in rat lungs

(2014) Paul M Peeters et al.   Particle and Fibre Toxicology

Effect of Silica Particle Size on Macrophage Inflammatory Responses

(2014) Toshimasa Kusaka et al.   PLoS One

NLRP1-Dependent Pyroptosis Leads to Acute Lung Injury and Morbidity in Mice

(2012) M. Kovarova et al.   JOURNAL OF IMMUNOLOGY

The IL-1-Dependent Sterile Inflammatory Response Has a Substantial Caspase-1-Independent Component That Requires Cathepsin C

(2012) H. Kono et al.   JOURNAL OF IMMUNOLOGY

Screening of different metal oxide nanoparticles reveals selective toxicity and inflammatory potential of silica nanoparticles in lung epithelial cells and macrophages

(2012) A. Panas et al.   Nanotoxicology

Comparison of non-crystalline silica nanoparticles in IL-1β release from macrophages

(2012) Wiggo J Sandberg et al.   Particle and Fibre Toxicology

Shape-controlled TiO2nanoparticles and TiO2P25 interacting with CO and H2O2molecular probes: a synergic approach for surface structure recognition and physico-chemical understanding

(2012) Chiara Deiana et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Differential Mouse Pulmonary Dose and Time Course Responses to Titanium Dioxide Nanospheres and Nanobelts

(2012) Dale W. Porter et al.   TOXICOLOGICAL SCIENCES

Induction of Inflammasome-dependent Pyroptosis by Carbon Black Nanoparticles

(2011) Anna C. Reisetter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Contrasting macrophage activation by fine and ultrafine titanium dioxide particles is associated with different uptake mechanisms

(2011) Agnes M Scherbart et al.   Particle and Fibre Toxicology

Titanium dioxide nanoparticles impair lung mitochondrial function

(2011) Verónica Freyre-Fonseca et al.   TOXICOLOGY LETTERS

Titanium dioxide induces different levels of IL-1β production dependent on its particle characteristics through caspase-1 activation mediated by reactive oxygen species and cathepsin B

(2010) Tomohiro Morishige et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Surface Iron Inhibits Quartz-Induced Cytotoxic and Inflammatory Responses in Alveolar Macrophages

(2010) Mara Ghiazza et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Neutrophil-derived ROS contribute to oxidative DNA damage induction by quartz particles

(2010) Damien van Berlo et al.   FREE RADICAL BIOLOGY AND MEDICINE

Activation of the inflammasome by amorphous silica and TiO2nanoparticles in murine dendritic cells

(2010) Meike Winter et al.   Nanotoxicology

NF-κB dependent and independent mechanisms of quartz-induced proinflammatory activation of lung epithelial cells

(2010) Damien van Berlo et al.   Particle and Fibre Toxicology

Nanomaterial cytotoxicity is composition, size, and cell type dependent

(2010) Syed K Sohaebuddin et al.   Particle and Fibre Toxicology

Immunological and Inflammatory Functions of the Interleukin-1 Family

(2009) Charles A. Dinarello   Annual Review of Immunology

Estimates of Upper Bounds and Trends in Nano-TiO2Production As a Basis for Exposure Assessment

(2009) Christine Ogilvie Robichaud et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Agglomeration and sedimentation of TiO2 nanoparticles in cell culture medium

(2008) Zouhir E. Allouni et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

A biocompatible medium for nanoparticle dispersion

(2008) Dale Porter et al.   Nanotoxicology

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY

Nanoparticle inhalation augments particle-dependent systemic microvascular dysfunction

(2008) Timothy R Nurkiewicz et al.   Particle and Fibre Toxicology

The Nalp3 inflammasome is essential for the development of silicosis

(2008) Suzanne L. Cassel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica

(2008) C. Dostert et al.   SCIENCE

Silica binding and toxicity in alveolar macrophages

(2007) Raymond F. Hamilton et al.   FREE RADICAL BIOLOGY AND MEDICINE