Pro-inflammatory adjuvant properties of pigment-grade titanium dioxide particles are augmented by a genotype that potentiates interleukin 1β processing

Frontline Science: Multiple cathepsins promote inflammasome-independent, particle-induced cell death during NLRP3-dependent IL-1β activation

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Quantitative biokinetics of titanium dioxide nanoparticles after oral application in rats: Part 2

(2017) Wolfgang G. Kreyling et al.   Nanotoxicology

The IBD interactome: an integrated view of aetiology, pathogenesis and therapy

(2017) Heitor S. P. de Souza et al.   Nature Reviews Gastroenterology & Hepatology

MyD88-dependent pro-interleukin-1β induction in dendritic cells exposed to food-grade synthetic amorphous silica

(2017) Hans Christian Winkler et al.   Particle and Fibre Toxicology

Food-grade TiO2 impairs intestinal and systemic immune homeostasis, initiates preneoplastic lesions and promotes aberrant crypt development in the rat colon

(2017) Sarah Bettini et al.   Scientific Reports

Food-grade titanium dioxide exposure exacerbates tumor formation in colitis associated cancer model

(2016) Ismael M. Urrutia-Ortega et al.   FOOD AND CHEMICAL TOXICOLOGY

Titanium dioxide nanoparticles exacerbate DSS-induced colitis: role of the NLRP3 inflammasome

(2016) Pedro A Ruiz et al.   GUT

Oral intake of added titanium dioxide and its nanofraction from food products, food supplements and toothpaste by the Dutch population

(2016) Cathy Rompelberg et al.   Nanotoxicology

Artefactual nanoparticle activation of the inflammasome platform: in vitro evidence with a nano-formed calcium phosphate

(2015) Laetitia Pele et al.   Nanomedicine

An endogenous nanomineral chaperones luminal antigen and peptidoglycan to intestinal immune cells

(2015) Jonathan J. Powell et al.   Nature Nanotechnology

Exogenous Pigment in Peyer Patches of Children Suspected of Having IBD

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Titanium dioxide nanoparticles: a review of current toxicological data

(2013) Hongbo Shi et al.   Particle and Fibre Toxicology

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Titanium dioxide induces different levels of IL-1β production dependent on its particle characteristics through caspase-1 activation mediated by reactive oxygen species and cathepsin B

(2010) Tomohiro Morishige et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Detection of TiO2 nanoparticles in cells by flow cytometry

(2010) R. M. Zucker et al.   CYTOMETRY PART A

Origin and fate of dietary nanoparticles and microparticles in the gastrointestinal tract

(2010) Jonathan J. Powell et al.   JOURNAL OF AUTOIMMUNITY

Activation of the inflammasome by amorphous silica and TiO2nanoparticles in murine dendritic cells

(2010) Meike Winter et al.   Nanotoxicology

Critical Evaluation of Nanoparticle Tracking Analysis (NTA) by NanoSight for the Measurement of Nanoparticles and Protein Aggregates

(2010) Vasco Filipe et al.   PHARMACEUTICAL RESEARCH

Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1  and IL-1 

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Immunological and Inflammatory Functions of the Interleukin-1 Family

(2009) Charles A. Dinarello   Annual Review of Immunology

Engineered nanomaterials cause cytotoxicity and activation on mouse antigen presenting cells

(2009) J. Palomäki et al.   TOXICOLOGY

Phenotype of exogenous microparticle-containing pigment cells of the human Peyer’s patch in inflamed and normal ileum

(2008) V. Thoree et al.   INFLAMMATION RESEARCH