Optical control of ERK and AKT signaling promotes axon regeneration and functional recovery of PNS and CNS in Drosophila

Long-Range Optogenetic Control of Axon Guidance Overcomes Developmental Boundaries and Defects

(2020) James M. Harris et al.   DEVELOPMENTAL CELL

Glial Metabolic Rewiring Promotes Axon Regeneration and Functional Recovery in the Central Nervous System

(2020) Feng Li et al.   Cell Metabolism

Light-based control of metabolic flux through assembly of synthetic organelles

(2019) Evan M. Zhao et al.   Nature Chemical Biology

Effects of Neurotrophic Factors in Glial Cells in the Central Nervous System: Expression and Properties in Neurodegeneration and Injury

(2019) Suvi Pöyhönen et al.   Frontiers in Physiology

Optogenetic neuronal stimulation promotes axon outgrowth and myelination of motor neurons in a three‐dimensional motor neuron–Schwann cell coculture model on a microfluidic biochip

(2019) Sujin Hyung et al.   BIOTECHNOLOGY AND BIOENGINEERING

Controlling protein conformation with light

(2019) Onur Dagliyan et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Optogenetic Control of Voltage-Gated Calcium Channels

(2018) Guolin Ma et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Optogenetically controlled protein kinases for regulation of cellular signaling

(2018) Anna V. Leopold et al.   CHEMICAL SOCIETY REVIEWS

Illuminating developmental biology with cellular optogenetics

(2018) Heath E Johnson et al.   CURRENT OPINION IN BIOTECHNOLOGY

Optogenetic regulation of engineered cellular metabolism for microbial chemical production

(2018) Evan M. Zhao et al.   NATURE

Intrinsic mechanisms of neuronal axon regeneration

(2018) Marcus Mahar et al.   NATURE REVIEWS NEUROSCIENCE

Near-infrared deep brain stimulation via upconversion nanoparticle–mediated optogenetics

(2018) Shuo Chen et al.   SCIENCE

Protein Phase Separation Provides Long-Term Memory of Transient Spatial Stimuli

(2018) Elliot Dine et al.   Cell Systems

A bright future: optogenetics to dissect the spatiotemporal control of cell behavior

(2018) Alexander G Goglia et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Applications of Optobiology in Intact Cells and Multicellular Organisms

(2017) John S. Khamo et al.   JOURNAL OF MOLECULAR BIOLOGY

Sustained MAPK/ERK Activation in Adult Schwann Cells Impairs Nerve Repair

(2017) Ilaria Cervellini et al.   JOURNAL OF NEUROSCIENCE

Phosphorylation of the C-Raf N Region Promotes Raf Dimerization

(2017) Maho Takahashi et al.   MOLECULAR AND CELLULAR BIOLOGY

A light- and calcium-gated transcription factor for imaging and manipulating activated neurons

(2017) Wenjing Wang et al.   NATURE BIOTECHNOLOGY

PI3K/Akt and ERK/MAPK Signaling Promote Different Aspects of Neuron Survival and Axonal Regrowth Following Rat Facial Nerve Axotomy

(2017) Haitao Huang et al.   NEUROCHEMICAL RESEARCH

Serotonergic Modulation Enables Pathway-Specific Plasticity in a Developing Sensory Circuit in Drosophila

(2017) Takuya Kaneko et al.   NEURON

Optical control of cell signaling by single-chain photoswitchable kinases

(2017) Xin X. Zhou et al.   SCIENCE

Neurotrophic factor and Trk signaling mechanisms underlying the promotion of motor recovery after acute spinal cord injury in rats

(2017) Hua Fang et al.   Experimental and Therapeutic Medicine

Dye-Sensitized Core/Active Shell Upconversion Nanoparticles for Optogenetics and Bioimaging Applications

(2016) Xiang Wu et al.   ACS Nano

Neurotrophin signalling: novel insights into mechanisms and pathophysiology

(2016) M. Mitre et al.   CLINICAL SCIENCE

Reversible optogenetic control of kinase activity during differentiation and embryonic development

(2016) Vishnu V. Krishnamurthy et al.   DEVELOPMENT

Intrinsic Control of Axon Regeneration

(2016) Zhigang He et al.   NEURON

GSK3β regulates AKT-induced central nervous system axon regeneration via an eIF2Bε-dependent, mTORC1-independent pathway

(2016) Xinzheng Guo et al.   eLife

mTORC1 is necessary but mTORC2 and GSK3β are inhibitory for AKT3-induced axon regeneration in the central nervous system

(2016) Linqing Miao et al.   eLife

The Timing of Raf/ERK and AKT Activation in Protecting PC12 Cells against Oxidative Stress

(2016) Qunxiang Ong et al.   PLoS One

Wireless Optofluidic Systems for Programmable In Vivo Pharmacology and Optogenetics

(2015) Jae-Woong Jeong et al.   CELL

Optogenetic stimulation of neuronal repair

(2015) Yan Xiao et al.   CURRENT BIOLOGY

Optogenetic control of endogenous Ca2+ channels in vivo

(2015) Taeyoon Kyung et al.   NATURE BIOTECHNOLOGY

Soft, stretchable, fully implantable miniaturized optoelectronic systems for wireless optogenetics

(2015) Sung Il Park et al.   NATURE BIOTECHNOLOGY

Regulation of axon regeneration by the RNA repair and splicing pathway

(2015) Yuanquan Song et al.   NATURE NEUROSCIENCE

Optogenetic control of intracellular signaling pathways

(2015) Kai Zhang et al.   TRENDS IN BIOTECHNOLOGY

Optogenetic control of nerve growth

(2015) Seongjun Park et al.   Scientific Reports

Near-infrared photoactivatable control of Ca2+ signaling and optogenetic immunomodulation

(2015) Lian He et al.   eLife

Nogo limits neural plasticity and recovery from injury

(2014) Martin E Schwab et al.   CURRENT OPINION IN NEUROBIOLOGY

Signaling regulations of neuronal regenerative ability

(2014) Yi Lu et al.   CURRENT OPINION IN NEUROBIOLOGY

B-RAF kinase drives developmental axon growth and promotes axon regeneration in the injured mature CNS

(2014) Kevin J. O’Donovan et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neuronal Regeneration in C. elegans Requires Subcellular Calcium Release by Ryanodine Receptor Channels and Can Be Enhanced by Optogenetic Stimulation

(2014) L. Sun et al.   JOURNAL OF NEUROSCIENCE

An optogenetic gene expression system with rapid activation and deactivation kinetics

(2014) Laura B Motta-Mena et al.   Nature Chemical Biology

Light-Mediated Kinetic Control Reveals the Temporal Effect of the Raf/MEK/ERK Pathway in PC12 Cell Neurite Outgrowth

(2014) Kai Zhang et al.   PLoS One

Dendrite morphogenesis depends on relative levels of NT-3/TrkC signaling

(2014) W. Joo et al.   SCIENCE

Dendrite Injury Triggers DLK-Independent Regeneration

(2014) Michelle C. Stone et al.   Cell Reports

Regeneration of Drosophila sensory neuron axons and dendrites is regulated by the Akt pathway involving Pten and microRNA bantam

(2012) Y. Song et al.   GENES & DEVELOPMENT

Nerve growth factor: from the early discoveries to the potential clinical use

(2012) Luigi Aloe et al.   Journal of Translational Medicine

Neuronal Intrinsic Mechanisms of Axon Regeneration

(2011) Kai Liu et al.   Annual Review of Neuroscience

Brain-Derived Neurotrophic Factor Promotes Central Nervous System Myelination via a Direct Effect upon Oligodendrocytes

(2011) Junhua Xiao et al.   NEUROSIGNALS

Enhancer-driven membrane markers for analysis of nonautonomous mechanisms reveal neuron-glia interactions in Drosophila

(2011) C. Han et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Self-amplifying autocrine actions of BDNF in axon development

(2011) P.-L. Cheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuronal intrinsic barriers for axon regeneration in the adult CNS

(2010) Fang Sun et al.   CURRENT OPINION IN NEUROBIOLOGY

Light-avoidance-mediating photoreceptors tile the Drosophila larval body wall

(2010) Yang Xiang et al.   NATURE

Rapid blue-light–mediated induction of protein interactions in living cells

(2010) Matthew J Kennedy et al.   NATURE METHODS

A genetically encoded photoactivatable Rac controls the motility of living cells

(2009) Yi I. Wu et al.   NATURE

Organization and Postembryonic Development of Glial Cells in the Adult Central Brain of Drosophila

(2008) T. Awasaki et al.   JOURNAL OF NEUROSCIENCE

ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation

(2008) Jer-Yen Yang et al.   NATURE CELL BIOLOGY

Promoting Axon Regeneration in the Adult CNS by Modulation of the PTEN/mTOR Pathway

(2008) K. K. Park et al.   SCIENCE