Optogenetic regulation of engineered cellular metabolism for microbial chemical production

Uncovering the role of branched-chain amino acid transaminases in Saccharomyces cerevisiae isobutanol biosynthesis

(2017) Sarah K. Hammer et al.   METABOLIC ENGINEERING

Improvement of isobutanol production in Saccharomyces cerevisiae by increasing mitochondrial import of pyruvate through mitochondrial pyruvate carrier

(2016) Seong-Hee Park et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

TAEL: a zebrafish-optimized optogenetic gene expression system with fine spatial and temporal control

(2016) Anna Reade et al.   DEVELOPMENT

Optimized second-generation CRY2–CIB dimerizers and photoactivatable Cre recombinase

(2016) Amir Taslimi et al.   Nature Chemical Biology

Blue light-mediated transcriptional activation and repression of gene expression in bacteria

(2016) Premkumar Jayaraman et al.   NUCLEIC ACIDS RESEARCH

Automated optogenetic feedback control for precise and robust regulation of gene expression and cell growth

(2016) Andreas Milias-Argeitis et al.   Nature Communications

Tunable switch mediated shikimate biosynthesis in an engineered non-auxotrophic Escherichia coli

(2016) Pengfei Gu et al.   Scientific Reports

An open-hardware platform for optogenetics and photobiology

(2016) Karl P. Gerhardt et al.   Scientific Reports

Engineering cellular redox balance inSaccharomyces cerevisiaefor improved production of L-lactic acid

(2015) Ju Young Lee et al.   BIOTECHNOLOGY AND BIOENGINEERING

Improvement of lactic acid production in Saccharomyces cerevisiae by a deletion of ssb1

(2015) Jinsuk J. Lee et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Dynamic knockdown of E. coli central metabolism for redirecting fluxes of primary metabolites

(2015) Irene M. Brockman et al.   METABOLIC ENGINEERING

Controlling Central Carbon Metabolism for Improved Pathway Yields in Saccharomyces cerevisiae

(2015) Sue Zanne Tan et al.   ACS Synthetic Biology

Photo-sensitive degron variants for tuning protein stability by light

(2014) Svetlana Usherenko et al.   BMC Systems Biology

An optogenetic gene expression system with rapid activation and deactivation kinetics

(2014) Laura B Motta-Mena et al.   Nature Chemical Biology

Secreting and Sensing the Same Molecule Allows Cells to Achieve Versatile Social Behaviors

(2014) H. Youk et al.   SCIENCE

Combinatorial Assembly of Large Biochemical Pathways into Yeast Chromosomes for Improved Production of Value-added Compounds

(2014) Jifeng Yuan et al.   ACS Synthetic Biology

Blue Light-Induced Dimerization of a Bacterial LOV–HTH DNA-Binding Protein

(2013) Brian D. Zoltowski et al.   BIOCHEMISTRY

Compartmentalization of metabolic pathways in yeast mitochondria improves the production of branched-chain alcohols

(2013) José L Avalos et al.   NATURE BIOTECHNOLOGY

Metabolic Engineering: Past and Future

(2013) Benjamin M. Woolston et al.   Annual Review of Chemical and Biomolecular Engineering

Identification of Natural and Artificial DNA Substrates for Light-Activated LOV–HTH Transcription Factor EL222

(2012) Giomar Rivera-Cancel et al.   BIOCHEMISTRY

New and Redesigned pRS Plasmid Shuttle Vectors for Genetic Manipulation of Saccharomyces cerevisiae

(2012) Mark K. Chee et al.   G3-Genes Genomes Genetics

Introduction and expression of genes for metabolic engineering applications in Saccharomyces cerevisiae

(2011) Nancy A. Da Silva et al.   FEMS YEAST RESEARCH

In silico feedback for in vivo regulation of a gene expression circuit

(2011) Andreas Milias-Argeitis et al.   NATURE BIOTECHNOLOGY

Structural basis of photosensitivity in a bacterial light-oxygen-voltage/helix-turn-helix (LOV-HTH) DNA-binding protein

(2011) A. I. Nash et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Optogenetics

(2010) Karl Deisseroth   NATURE METHODS

The promise of optogenetics in cell biology: interrogating molecular circuits in space and time

(2010) Jared E Toettcher et al.   NATURE METHODS

Rapid blue-light–mediated induction of protein interactions in living cells

(2010) Matthew J Kennedy et al.   NATURE METHODS

Manufacturing Molecules Through Metabolic Engineering

(2010) J. D. Keasling   SCIENCE

Isoprenoid Pathway Optimization for Taxol Precursor Overproduction in Escherichia coli

(2010) P. K. Ajikumar et al.   SCIENCE

Enzymatic assembly of DNA molecules up to several hundred kilobases

(2009) Daniel G Gibson et al.   NATURE METHODS