The NTP generating activity of pyruvate kinase II is critical for apicoplast maintenance in Plasmodium falciparum

Functional and Computational Genomics Reveal Unprecedented Flexibility in Stage-Specific Toxoplasma Metabolism

(2020) Aarti Krishnan et al.   Cell Host & Microbe

A mevalonate bypass system facilitates elucidation of plastid biology in malaria parasites

(2020) Russell P. Swift et al.   PLoS Pathogens

Acquisition of exogenous fatty acids renders apicoplast-based biosynthesis dispensable in tachyzoites of Toxoplasma

(2020) Xiaohan Liang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Redesigned TetR-Aptamer System To Control Gene Expression in Plasmodium falciparum

(2020) Krithika Rajaram et al.   mSphere

Development of a conditional localization approach to control apicoplast protein trafficking in malaria parasites

(2019) Aleah D. Roberts et al.   TRAFFIC

Pyruvate Homeostasis as a Determinant of Parasite Growth and Metabolic Plasticity in Toxoplasma gondii

(2019) Ningbo Xia et al.   mBio

Uncovering the essential genes of the human malaria parasitePlasmodium falciparumby saturation mutagenesis

(2018) Min Zhang et al.   SCIENCE

The Plasmodium falciparum male gametocyte protein P230p, a paralog of P230, is vital for ookinete formation and mosquito transmission

(2018) Catherin Marin-Mogollon et al.   Scientific Reports

Integrative proteomics and bioinformatic prediction enable a high-confidence apicoplast proteome in malaria parasites

(2018) Michael J. Boucher et al.   PLOS BIOLOGY

Use of luciferase probes to measure ATP in living cells and animals

(2017) Giampaolo Morciano et al.   Nature Protocols

Review: Translational GTPases

(2016) Cristina Maracci et al.   BIOPOLYMERS

Synthetic RNA–protein modules integrated with native translation mechanisms to control gene expression in malaria parasites

(2016) Suresh M. Ganesan et al.   Nature Communications

Targeting of a Transporter to the Outer Apicoplast Membrane in the Human Malaria Parasite Plasmodium falciparum

(2016) Liting Lim et al.   PLoS One

Biochemical and structural characterization of the apicoplast dihydrolipoamide dehydrogenase ofPlasmodium falciparum

(2015) Larissa M. Laine et al.   BIOSCIENCE REPORTS

PlasmoGEM, a database supporting a community resource for large-scale experimental genetics in malaria parasites

(2015) Frank Schwach et al.   NUCLEIC ACIDS RESEARCH

Pyruvate kinase: Function, regulation and role in cancer

(2015) William J. Israelsen et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Magnetic isolation of Plasmodium falciparum schizonts iRBCs to generate a high parasitaemia and synchronized in vitro culture

(2014) Lydia Mata-Cantero et al.   MALARIA JOURNAL

Genome editing in the human malaria parasite Plasmodium falciparum using the CRISPR-Cas9 system

(2014) Mehdi Ghorbal et al.   NATURE BIOTECHNOLOGY

Efficient CRISPR-Cas9–mediated genome editing in Plasmodium falciparum

(2014) Jeffrey C Wagner et al.   NATURE METHODS

tRNA synthetase: tRNA aminoacylation and beyond

(2014) Yan Ling Joy Pang et al.   Wiley Interdisciplinary Reviews-RNA

Chemical and enzymatic characterization of recombinant rabbit muscle pyruvate kinase

(2013) Christian Boehme et al.   BIOLOGICAL CHEMISTRY

Type II Fatty Acid Biosynthesis Is Essential for Plasmodium falciparum Sporozoite Development in the Midgut of Anopheles Mosquitoes

(2013) Ben C. L. van Schaijk et al.   EUKARYOTIC CELL

Kinetic Flux Profiling Elucidates Two Independent Acetyl-CoA Biosynthetic Pathways inPlasmodium falciparum

(2013) Simon A. Cobbold et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Suf Iron-Sulfur Cluster Synthesis Pathway Is Required for Apicoplast Maintenance in Malaria Parasites

(2013) Jolyn E. Gisselberg et al.   PLoS Pathogens

Toxoplasma gondii Relies on Both Host and Parasite Isoprenoids and Can Be Rendered Sensitive to Atorvastatin

(2013) Zhu-Hong Li et al.   PLoS Pathogens

Targeting apicoplasts in malaria parasites

(2012) Christopher D Goodman et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

New Agilent platform DNA microarrays for transcriptome analysis of Plasmodium falciparum and Plasmodium berghei for the malaria research community

(2012) Björn F C Kafsack et al.   MALARIA JOURNAL

Apicoplast triose phosphate transporter (TPT) gene knockout is lethal for Plasmodium

(2012) Tanushree Banerjee et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Biochemical and structural characterization of Plasmodium falciparum glutamate dehydrogenase 2

(2012) Kathleen Zocher et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Apicoplast isoprenoid precursor synthesis and the molecular basis of fosmidomycin resistance inToxoplasma gondii

(2011) Sethu C. Nair et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Import and Export Business in Plastids: Transport Processes across the Inner Envelope Membrane

(2011) K. Fischer   PLANT PHYSIOLOGY

Chemical Rescue of Malaria Parasites Lacking an Apicoplast Defines Organelle Function in Blood-Stage Plasmodium falciparum

(2011) Ellen Yeh et al.   PLOS BIOLOGY

The Metabolite Transporters of the Plastid Envelope: An Update

(2011) Fabio Facchinelli et al.   Frontiers in Plant Science

SufD and SufC ATPase Activity Are Required for Iron Acquisition during in Vivo Fe-S Cluster Formation on SufB

(2010) Avneesh Saini et al.   BIOCHEMISTRY

Plasmodium falciparum proteome changes in response to doxycycline treatment

(2010) Sébastien Briolant et al.   MALARIA JOURNAL

Validation of a modified method for Bxb1 mycobacteriophage integrase-mediated recombination in Plasmodium falciparum by localization of the H-protein of the glycine cleavage complex to the mitochondrion

(2010) Maroya D. Spalding et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Plasmodiumpyruvate dehydrogenase activity is only essential for the parasite's progression from liver infection to blood infection

(2010) Ying Pei et al.   MOLECULAR MICROBIOLOGY

The evolution, metabolism and functions of the apicoplast

(2010) L. Lim et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

A common red algal origin of the apicomplexan, dinoflagellate, and heterokont plastids

(2010) J. Janouskovec et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA Polymerase Active Center: The Molecular Engine of Transcription

(2009) Evgeny Nudler   Annual Review of Biochemistry

The carbon and energy sources of the non-photosynthetic plastid in the malaria parasite

(2009) Liting Lim et al.   FEBS LETTERS

Artemisinin Resistance inPlasmodium falciparumMalaria

(2009) Arjen M. Dondorp et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Novel GDP-dependent Pyruvate Kinase Isozyme fromToxoplasma gondiiLocalizes to Both the Apicoplast and the Mitochondrion

(2008) Tomoya Saito et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metabolite profiling of the intraerythrocytic malaria parasitePlasmodium falciparumby1H NMR spectroscopy

(2008) Rongwei Teng et al.   NMR IN BIOMEDICINE

Pyruvate kinase type-II isozyme in Plasmodium falciparum localizes to the apicoplast

(2008) Takuya Maeda et al.   PARASITOLOGY INTERNATIONAL