Integrative proteomics and bioinformatic prediction enable a high-confidence apicoplast proteome in malaria parasites

Identification of novel parasitophorous vacuole proteins in P. falciparum parasites using BioID

(2018) Melissa Khosh-Naucke et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Uncovering the essential genes of the human malaria parasitePlasmodium falciparumby saturation mutagenesis

(2018) Min Zhang et al.   SCIENCE

BioID Reveals Novel Proteins of the Plasmodium Parasitophorous Vacuole Membrane

(2018) Cilly Bernardette Schnider et al.   mSphere

Small molecule inhibition of apicomplexan FtsH1 disrupts plastid biogenesis in human pathogens

(2017) Katherine Amberg-Johnson et al.   eLife

A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes

(2016) Saima M. Sidik et al.   CELL

Novel insights into the composition and function of the Toxoplasma IMC sutures

(2016) Allan L. Chen et al.   CELLULAR MICROBIOLOGY

Proteomic Analysis of thePlasmodium bergheiGametocyte Egressome and Vesicular bioID of Osmiophilic Body Proteins Identifies Merozoite TRAP-like Protein (MTRAP) as an Essential Factor for Parasite Transmission

(2016) Jessica Kehrer et al.   MOLECULAR & CELLULAR PROTEOMICS

Vital and dispensable roles ofPlasmodiummultidrug resistance transporters during blood- and mosquito-stage development

(2016) Sanna R. Rijpma et al.   MOLECULAR MICROBIOLOGY

Protein-protein interactions indicate composition of a 480 kDa SELMA complex in the second outermost membrane of diatom complex plastids

(2016) Julia B. Lau et al.   MOLECULAR MICROBIOLOGY

EuPathDB: the eukaryotic pathogen genomics database resource

(2016) Cristina Aurrecoechea et al.   NUCLEIC ACIDS RESEARCH

In Vivo Biotinylation of the Toxoplasma Parasitophorous Vacuole Reveals Novel Dense Granule Proteins Important for Parasite Growth and Pathogenesis

(2016) Santhosh M. Nadipuram et al.   mBio

Synthetic RNA–protein modules integrated with native translation mechanisms to control gene expression in malaria parasites

(2016) Suresh M. Ganesan et al.   Nature Communications

MitoCarta2.0: an updated inventory of mammalian mitochondrial proteins

(2015) Sarah E. Calvo et al.   NUCLEIC ACIDS RESEARCH

A Chemical Rescue Screen Identifies a Plasmodium falciparum Apicoplast Inhibitor Targeting MEP Isoprenoid Precursor Biosynthesis

(2014) Wesley Wu et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Heme Biosynthesis Pathway Is Essential forPlasmodium falciparumDevelopment in Mosquito Stage but Not in Blood Stages

(2014) Hangjun Ke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Efficient CRISPR-Cas9–mediated genome editing in Plasmodium falciparum

(2014) Jeffrey C Wagner et al.   NATURE METHODS

The ABC-F protein EttA gates ribosome entry into the translation elongation cycle

(2014) Grégory Boël et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

EttA regulates translation by binding the ribosomal E site and restricting ribosome-tRNA dynamics

(2014) Bo Chen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Versatile control of Plasmodium falciparum gene expression with an inducible protein–RNA interaction

(2014) Stephen J. Goldfless et al.   Nature Communications

The Algal Past and Parasite Present of the Apicoplast

(2013) Giel G. van Dooren et al.   Annual Review of Microbiology

The roles of intramembrane proteases in protozoan parasites

(2013) L. David Sibley   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The metabolic roles of the endosymbiotic organelles of Toxoplasma and Plasmodium spp.

(2013) Lilach Sheiner et al.   CURRENT OPINION IN MICROBIOLOGY

Loss-of-function analyses defines vital and redundant functions of thePlasmodiumrhomboid protease family

(2013) Jing-wen Lin et al.   MOLECULAR MICROBIOLOGY

Proteomic Mapping of Mitochondria in Living Cells via Spatially Restricted Enzymatic Tagging

(2013) H.-W. Rhee et al.   SCIENCE

An Apicoplast Localized Ubiquitylation System Is Required for the Import of Nuclear-encoded Plastid Proteins

(2013) Swati Agrawal et al.   PLoS Pathogens

Malaria Parasite-Synthesized Heme Is Essential in the Mosquito and Liver Stages and Complements Host Heme in the Blood Stages of Infection

(2013) Viswanathan Arun Nagaraj et al.   PLoS Pathogens

Novel Bilobe Components in Trypanosoma brucei Identified Using Proximity-Dependent Biotinylation

(2012) Brooke Morriswood et al.   EUKARYOTIC CELL

A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells

(2012) Kyle J. Roux et al.   JOURNAL OF CELL BIOLOGY

ApicoAP: The First Computational Model for Identifying Apicoplast-Targeted Proteins in Multiple Species of Apicomplexa

(2012) Gokcen Cilingir et al.   PLoS One

ATP Synthase Complex ofPlasmodium falciparum

(2011) Praveen Balabaskaran Nina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chemical Rescue of Malaria Parasites Lacking an Apicoplast Defines Organelle Function in Blood-Stage Plasmodium falciparum

(2011) Ellen Yeh et al.   PLOS BIOLOGY

A Systematic Screen to Discover and Analyze Apicoplast Proteins Identifies a Conserved and Essential Protein Import Factor

(2011) Lilach Sheiner et al.   PLoS Pathogens

The Mitochondrial Proteome and Human Disease

(2010) Sarah E. Calvo et al.   Annual Review of Genomics and Human Genetics

A Tissue-Specific Atlas of Mouse Protein Phosphorylation and Expression

(2010) Edward L. Huttlin et al.   CELL

The Clp Chaperones and Proteases of the Human Malaria Parasite Plasmodium falciparum

(2010) Majida El Bakkouri et al.   JOURNAL OF MOLECULAR BIOLOGY

Plasmodiumpyruvate dehydrogenase activity is only essential for the parasite's progression from liver infection to blood infection

(2010) Ying Pei et al.   MOLECULAR MICROBIOLOGY

H2A.Z Demarcates Intergenic Regions of the Plasmodium falciparum Epigenome That Are Dynamically Marked by H3K9ac and H3K4me3

(2010) Richárd Bártfai et al.   PLoS Pathogens

GFP-targeting allows visualization of the apicoplast throughout the life cycle of live malaria parasites

(2009) Rebecca R. Stanway et al.   BIOLOGY OF THE CELL

An Unusual ERAD-Like Complex Is Targeted to the Apicoplast ofPlasmodium falciparum

(2009) Simone Spork et al.   EUKARYOTIC CELL

Characterization of Two Putative Protein Translocation Components in the Apicoplast ofPlasmodium falciparum

(2009) Ming Kalanon et al.   EUKARYOTIC CELL

ABC50 Promotes Translation Initiation in Mammalian Cells

(2009) Sonia Paytubi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetic Evidence that an Endosymbiont-derived Endoplasmic Reticulum-associated Protein Degradation (ERAD) System Functions in Import of Apicoplast Proteins

(2009) Swati Agrawal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Fatty Acid Biosynthesis Enzyme FabI Plays a Key Role in the Development of Liver-Stage Malarial Parasites

(2008) Min Yu et al.   Cell Host & Microbe

Type II fatty acid synthesis is essential only for malaria parasite late liver stage development

(2008) Ashley M. Vaughan et al.   CELLULAR MICROBIOLOGY