Toxoplasma gondii Relies on Both Host and Parasite Isoprenoids and Can Be Rendered Sensitive to Atorvastatin

Cloning and characterization of bifunctional enzyme farnesyl diphosphate/geranylgeranyl diphosphate synthase from Plasmodium falciparum

(2013) Fabiana M Jordão et al.   MALARIA JOURNAL

Overexpression of a cytosolic pyrophosphatase (TgPPase) reveals a regulatory role of PPiin glycolysis forToxoplasma gondii

(2011) Douglas A. Pace et al.   BIOCHEMICAL JOURNAL

Atorvastatin and pitavastatin protect cerebellar Purkinje cells in AD model mice and preserve the cytokines MCP-1 and TNF-α

(2011) Miki Kozuki et al.   BRAIN RESEARCH

A Toxoplasma gondii protein with homology to intracellular type Na+/H+ exchangers is important for osmoregulation and invasion

(2011) Maria E. Francia et al.   EXPERIMENTAL CELL RESEARCH

Apicoplast isoprenoid precursor synthesis and the molecular basis of fosmidomycin resistance inToxoplasma gondii

(2011) Sethu C. Nair et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Atorvastatin prevents Plasmodium falciparum cytoadherence and endothelial damage

(2011) Zacharie Taoufiq et al.   MALARIA JOURNAL

Fosmidomycin Uptake into Plasmodium and Babesia-Infected Erythrocytes Is Facilitated by Parasite-Induced New Permeability Pathways

(2011) Stefan Baumeister et al.   PLoS One

What Do Human Parasites Do with a Chloroplast Anyway?

(2011) Sethu C. Nair et al.   PLOS BIOLOGY

Chemical Rescue of Malaria Parasites Lacking an Apicoplast Defines Organelle Function in Blood-Stage Plasmodium falciparum

(2011) Ellen Yeh et al.   PLOS BIOLOGY

Targeting Isoprenoid Biosynthesis for Drug Discovery: Bench to Bedside

(2010) Eric Oldfield   ACCOUNTS OF CHEMICAL RESEARCH

The Toxoplasma Apicoplast Phosphate Translocator Links Cytosolic and Apicoplast Metabolism and Is Essential for Parasite Survival

(2010) Carrie F. Brooks et al.   Cell Host & Microbe

Long-term high-dose atorvastatin decreases brain oxidative and nitrosative stress in a preclinical model of Alzheimer disease: A novel mechanism of action

(2010) Eugenio Barone et al.   PHARMACOLOGICAL RESEARCH

Efficient Gene Replacements inToxoplasma gondiiStrains Deficient for Nonhomologous End Joining

(2009) Barbara A. Fox et al.   EUKARYOTIC CELL

Tagging of Endogenous Genes in aToxoplasma gondiiStrain Lacking Ku80

(2009) My-Hang Huynh et al.   EUKARYOTIC CELL

The Plastid-Like Organelle of Apicomplexan Parasites as Drug Target

(2008) J. Wiesner et al.   CURRENT PHARMACEUTICAL DESIGN