Acquisition of exogenous fatty acids renders apicoplast-based biosynthesis dispensable in tachyzoites of Toxoplasma

Functional and Computational Genomics Reveal Unprecedented Flexibility in Stage-Specific Toxoplasma Metabolism

(2020) Aarti Krishnan et al.   Cell Host & Microbe

Micronemal protein 13 contributes to the optimal growth of Toxoplasma gondii under stress conditions

(2019) Shu Ye et al.   PARASITOLOGY RESEARCH

Pyruvate Homeostasis as a Determinant of Parasite Growth and Metabolic Plasticity in Toxoplasma gondii

(2019) Ningbo Xia et al.   mBio

Tagging of Weakly Expressed Toxoplasma gondii Calcium-Related Genes with High-Affinity Tags

(2018) Miryam A. Hortua Triana et al.   JOURNAL OF EUKARYOTIC MICROBIOLOGY

Role of the Pyruvate Dehydrogenase Complex in Metabolic Remodeling: Differential Pyruvate Dehydrogenase Complex Functions in Metabolism

(2018) Sungmi Park et al.   Diabetes & Metabolism Journal

The apicoplast: now you see it, now you don’t

(2017) Geoffrey Ian McFadden et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Calmodulin-like proteins localized to the conoid regulate motility and cell invasion by Toxoplasma gondii

(2017) Shaojun Long et al.   PLoS Pathogens

Host lipid droplets: An important source of lipids salvaged by the intracellular parasite Toxoplasma gondii

(2017) Sabrina J. Nolan et al.   PLoS Pathogens

Fatty acid metabolism in the Plasmodium apicoplast: Drugs, doubts and knockouts

(2015) Melanie J. Shears et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

The intracellular parasiteToxoplasma gondiidepends on the synthesis of long-chain and very long-chain unsaturated fatty acids not supplied by the host cell

(2015) Srinivasan Ramakrishnan et al.   MOLECULAR MICROBIOLOGY

The Pyruvate Dehydrogenase Complexes: Structure-based Function and Regulation

(2014) Mulchand S. Patel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Efficient Gene Disruption in Diverse Strains of Toxoplasma gondii Using CRISPR/CAS9

(2014) B. Shen et al.   mBio

BCKDH: The Missing Link in Apicomplexan Mitochondrial Metabolism Is Required for Full Virulence of Toxoplasma gondii and Plasmodium berghei

(2014) Rebecca D. Oppenheim et al.   PLoS Pathogens

Regulation of pyruvate metabolism and human disease

(2013) Lawrence R. Gray et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Type II Fatty Acid Biosynthesis Is Essential for Plasmodium falciparum Sporozoite Development in the Midgut of Anopheles Mosquitoes

(2013) Ben C. L. van Schaijk et al.   EUKARYOTIC CELL

Kinetic Flux Profiling Elucidates Two Independent Acetyl-CoA Biosynthetic Pathways inPlasmodium falciparum

(2013) Simon A. Cobbold et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting lipid biosynthesis and salvage in apicomplexan parasites for improved chemotherapies

(2013) Isabelle Coppens   NATURE REVIEWS MICROBIOLOGY

Lipid synthesis in protozoan parasites: A comparison between kinetoplastids and apicomplexans

(2013) Srinivasan Ramakrishnan et al.   PROGRESS IN LIPID RESEARCH

Mitochondrial Metabolism of Glucose and Glutamine Is Required for Intracellular Growth of Toxoplasma gondii

(2012) James I. MacRae et al.   Cell Host & Microbe

Foodborne Toxoplasmosis

(2012) J. L. Jones et al.   CLINICAL INFECTIOUS DISEASES

A rapid GC–MS method for quantification of positional and geometric isomers of fatty acid methyl esters

(2012) Josef Ecker et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Apicoplast and Endoplasmic Reticulum Cooperate in Fatty Acid Biosynthesis in Apicomplexan ParasiteToxoplasma gondii

(2011) Srinivasan Ramakrishnan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Plasmodiumpyruvate dehydrogenase activity is only essential for the parasite's progression from liver infection to blood infection

(2010) Ying Pei et al.   MOLECULAR MICROBIOLOGY

Toxoplasma gondii: epidemiology, feline clinical aspects, and prevention

(2010) Stacey A. Elmore et al.   TRENDS IN PARASITOLOGY

Tagging of Endogenous Genes in aToxoplasma gondiiStrain Lacking Ku80

(2009) My-Hang Huynh et al.   EUKARYOTIC CELL

Catalysis and mechanism of malonyl transferase activity in type II fatty acid biosynthesis acyl carrier proteins

(2009) Ashish Misra et al.   Molecular BioSystems

Host-derived glucose and its transporter in the obligate intracellular pathogen Toxoplasma gondii are dispensable by glutaminolysis

(2009) M. Blume et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Type II fatty acid synthesis is essential only for malaria parasite late liver stage development

(2008) Ashley M. Vaughan et al.   CELLULAR MICROBIOLOGY