Synthetic RNA–protein modules integrated with native translation mechanisms to control gene expression in malaria parasites

Mutations in the P-Type Cation-Transporter ATPase 4, PfATP4, Mediate Resistance to Both Aminopyrazole and Spiroindolone Antimalarials

(2014) Erika L. Flannery et al.   ACS Chemical Biology

Diverse chemotypes disrupt ion homeostasis in the malaria parasite

(2014) Adele M. Lehane et al.   MOLECULAR MICROBIOLOGY

A general design strategy for protein-responsive riboswitches in mammalian cells

(2014) Simon Ausländer et al.   NATURE METHODS

Human DDX6 effects miRNA-mediated gene silencing via direct binding to CNOT1

(2014) Christopher Rouya et al.   RNA

Versatile control of Plasmodium falciparum gene expression with an inducible protein–RNA interaction

(2014) Stephen J. Goldfless et al.   Nature Communications

Na+ Regulation in the Malaria Parasite Plasmodium falciparum Involves the Cation ATPase PfATP4 and Is a Target of the Spiroindolone Antimalarials

(2013) Natalie J. Spillman et al.   Cell Host & Microbe

Plasmodium falciparum DOZI, an RNA helicase interacts with eIF4E

(2013) Mohammed Tarique et al.   GENE

An integrated strategy for efficient vector construction and multi-gene expression in Plasmodium falciparum

(2013) Jeffrey C Wagner et al.   MALARIA JOURNAL

Inducible Knockdown of Plasmodium Gene Expression Using the glmS Ribozyme

(2013) Parichat Prommana et al.   PLoS One

Direct and specific chemical control of eukaryotic translation with a synthetic RNA–protein interaction

(2012) Stephen J. Goldfless et al.   NUCLEIC ACIDS RESEARCH

Inducible Control of Subcellular RNA Localization Using a Synthetic Protein-RNA Aptamer Interaction

(2012) Brian J. Belmont et al.   PLoS One

Multiple binding of repressed mRNAs by the P-body protein Rck/p54

(2012) M. Ernoult-Lange et al.   RNA

P-Bodies and Stress Granules: Possible Roles in the Control of Translation and mRNA Degradation

(2012) C. J. Decker et al.   Cold Spring Harbor Perspectives in Biology

Selection of tetracycline inducible self-cleaving ribozymes as synthetic devices for gene regulation in yeast

(2011) Alexander Wittmann et al.   Molecular BioSystems

Quantitative assessment of Plasmodium falciparum sexual development reveals potent transmission-blocking activity by methylene blue

(2011) S. H. Adjalley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Engineering a Direct and Inducible Protein−RNA Interaction To Regulate RNA Biology

(2010) Brian J. Belmont et al.   ACS Chemical Biology

Spiroindolones, a Potent Compound Class for the Treatment of Malaria

(2010) M. Rottmann et al.   SCIENCE

Universal Features of Post-Transcriptional Gene Regulation Are Critical for Plasmodium Zygote Development

(2010) Gunnar R. Mair et al.   PLoS Pathogens

Synthetic translational regulation by an L7Ae–kink-turn RNP switch

(2009) Hirohide Saito et al.   Nature Chemical Biology

Translational control of localized mRNAs: restricting protein synthesis in space and time

(2008) Florence Besse et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY