Genetic variation in the MacAB-TolC efflux pump influences pathogenesis of invasive Salmonella isolates from Africa

Linearized Siderophore Products Secreted via MacAB Efflux Pump Protect Salmonella enterica Serovar Typhimurium from Oxidative Stress

(2020) L. M. Bogomolnaya et al.   mBio

Adding function to the genome of African Salmonella Typhimurium ST313 strain D23580

(2019) Rocío Canals et al.   PLOS BIOLOGY

RAxML-NG: a fast, scalable and user-friendly tool for maximum likelihood phylogenetic inference

(2019) Alexey M Kozlov et al.   BIOINFORMATICS

The global burden of typhoid and paratyphoid fevers: a systematic analysis for the Global Burden of Disease Study 2017

(2019) Jeffrey D Stanaway et al.   LANCET INFECTIOUS DISEASES

Parallel evolution leading to impaired biofilm formation in invasive Salmonella strains

(2019) Keith D. MacKenzie et al.   PLoS Genetics

The use of chicken and insect infection models to assess the virulence of African Salmonella Typhimurium ST313

(2019) Lizeth Lacharme-Lora et al.   PLoS Neglected Tropical Diseases

The global burden of non-typhoidal salmonella invasive disease: a systematic analysis for the Global Burden of Disease Study 2017

(2019) Jeffrey D. Stanaway et al.   LANCET INFECTIOUS DISEASES

The fitness landscape of the African Salmonella Typhimurium ST313 strain D23580 reveals unique properties of the pBT1 plasmid

(2019) Rocío Canals et al.   PLoS Pathogens

Host resistance factor SLC11A1 restricts Salmonella growth through magnesium deprivation

(2019) Olivier Cunrath et al.   SCIENCE

An African Salmonella Typhimurium ST313 sublineage with extensive drug-resistance and signatures of host adaptation

(2019) Sandra Van Puyvelde et al.   Nature Communications

Genetically distinct lineages of Salmonella Typhimurium ST313 and ST19 are present in Brazil

(2018) Pedro Henrique N. Panzenhagen et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

The malS -5′UTR weakens the ability of Salmonella enterica serovar Typhi to survive in macrophages by increasing intracellular ATP levels

(2018) Fang Dong et al.   MICROBIAL PATHOGENESIS

Trans-envelope multidrug efflux pumps of Gram-negative bacteria and their synergism with the outer membrane barrier

(2018) Helen I. Zgurskaya et al.   RESEARCH IN MICROBIOLOGY

Gene expression kinetics governs stimulus-specific decoration of theSalmonellaouter membrane

(2018) Xinyu Hong et al.   Science Signaling

Evolution of Salmonella within Hosts

(2018) Jennifer R. Tanner et al.   TRENDS IN MICROBIOLOGY

Risk of nontyphoidal Salmonella bacteraemia in African children is modified by STAT4

(2018) James J. Gilchrist et al.   Nature Communications

A cell-based infection assay identifies efflux pump modulators that reduce bacterial intracellular load

(2018) Abigail L. Reens et al.   PLoS Pathogens

Antibiotic Resistance Mediated by the MacB ABC Transporter Family: A Structural and Functional Perspective

(2018) Nicholas P. Greene et al.   Frontiers in Microbiology

Gene expression kinetics governs stimulus-specific decoration of theSalmonellaouter membrane

(2018) Xinyu Hong et al.   Science Signaling

A Gut Commensal-Produced Metabolite Mediates Colonization Resistance to Salmonella Infection

(2018) Amanda Jacobson et al.   Cell Host & Microbe

Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: a systematic analysis for the Global Burden of Disease Study 2017

(2018) Gregory A Roth et al.   LANCET

Multilocus sequence typing of Salmonella Typhimurium reveals the presence of the highly invasive ST313 in Brazil

(2017) Fernanda Almeida et al.   INFECTION GENETICS AND EVOLUTION

Atrans-acting leader RNA from aSalmonellavirulence gene

(2017) Eunna Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure and mechanotransmission mechanism of the MacB ABC transporter superfamily

(2017) Allister Crow et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lack of AcrB Efflux Function Confers Loss of Virulence on Salmonella enterica Serovar Typhimurium

(2017) Xuan Wang-Kan et al.   mBio

Public health surveillance in the UK revolutionises our understanding of the invasive Salmonella Typhimurium epidemic in Africa

(2017) Philip M. Ashton et al.   Genome Medicine

Unicycler: Resolving bacterial genome assemblies from short and long sequencing reads

(2017) Ryan R. Wick et al.   PLoS Computational Biology

Virulence of invasive Salmonella Typhimurium ST313 in animal models of infection

(2017) Girish Ramachandran et al.   PLoS Neglected Tropical Diseases

Incidence of invasive salmonella disease in sub-Saharan Africa: a multicentre population-based surveillance study

(2017) Florian Marks et al.   Lancet Global Health

Structure of the MacAB–TolC ABC-type tripartite multidrug efflux pump

(2017) Anthony W. P. Fitzpatrick et al.   Nature Microbiology

Single-step method for β-galactosidase assays in Escherichia coli using a 96-well microplate reader

(2016) Jorrit Schaefer et al.   ANALYTICAL BIOCHEMISTRY

Reducing Ribosome Biosynthesis Promotes Translation during Low Mg 2+ Stress

(2016) Mauricio H. Pontes et al.   MOLECULAR CELL

Acidic pH sensing in the bacterial cytoplasm is required for Salmonella virulence

(2016) Jeongjoon Choi et al.   MOLECULAR MICROBIOLOGY

Distinct Salmonella Enteritidis lineages associated with enterocolitis in high-income settings and invasive disease in low-income settings

(2016) Nicholas A Feasey et al.   NATURE GENETICS

Loss of Multicellular Behavior in Epidemic African Nontyphoidal Salmonella enterica Serovar Typhimurium ST313 Strain D23580

(2016) Larissa A. Singletary et al.   mBio

The Impact of 18 Ancestral and Horizontally-Acquired Regulatory Proteins upon the Transcriptome and sRNA Landscape of Salmonella enterica serovar Typhimurium

(2016) Aoife M. Colgan et al.   PLoS Genetics

Ceftriaxone-Resistant Salmonella enterica Serotype Typhimurium Sequence Type 313 from Kenyan Patients Is Associated with theblaCTX-M-15Gene on a Novel IncHI2 Plasmid

(2015) Samuel Kariuki et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The transcriptomic response ofAcinetobacter baumanniito colistin and doripenem alone and in combination in anin vitropharmacokinetics/pharmacodynamics model

(2015) Rebekah Henry et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

The Phyre2 web portal for protein modeling, prediction and analysis

(2015) Lawrence A Kelley et al.   Nature Protocols

Signatures of Adaptation in Human Invasive Salmonella Typhimurium ST313 Populations from Sub-Saharan Africa

(2015) Chinyere K. Okoro et al.   PLoS Neglected Tropical Diseases

Characterization of the Invasive, Multidrug Resistant Non-typhoidal Salmonella Strain D23580 in a Murine Model of Infection

(2015) Jiseon Yang et al.   PLoS Neglected Tropical Diseases

Modelling the Contributions of Malaria, HIV, Malnutrition and Rainfall to the Decline in Paediatric Invasive Non-typhoidal Salmonella Disease in Malawi

(2015) Nicholas A. Feasey et al.   PLoS Neglected Tropical Diseases

Invasive Salmonella Typhimurium ST313 with Naturally Attenuated Flagellin Elicits Reduced Inflammation and Replicates within Macrophages

(2015) Girish Ramachandran et al.   PLoS Neglected Tropical Diseases

RNA-seq Brings New Insights to the Intra-Macrophage Transcriptome of Salmonella Typhimurium

(2015) Shabarinath Srikumar et al.   PLoS Pathogens

Non-typhoidal Salmonella Typhimurium ST313 isolates that cause bacteremia in humans stimulate less inflammasome activation than ST19 isolates associated with gastroenteritis

(2015) Sarah Carden et al.   Pathogens and Disease

Salmonellae PhoPQ regulation of the outer membrane to resist innate immunity

(2014) Zachary D Dalebroux et al.   CURRENT OPINION IN MICROBIOLOGY

Rapid phylogenetic analysis of large samples of recombinant bacterial whole genome sequences using Gubbins

(2014) Nicholas J. Croucher et al.   NUCLEIC ACIDS RESEARCH

Inflammation Fuels Colicin Ib-Dependent Competition of Salmonella Serovar Typhimurium and E. coli in Enterobacterial Blooms

(2014) Lubov Petkova Nedialkova et al.   PLoS Pathogens

Protoporphyrin (PPIX) efflux by the MacAB-TolC pump inEscherichia coli

(2014) Evelyne Turlin et al.   MicrobiologyOpen

QUAST: quality assessment tool for genome assemblies

(2013) Alexey Gurevich et al.   BIOINFORMATICS

An Infection-Relevant Transcriptomic Compendium for Salmonella enterica Serovar Typhimurium

(2013) Carsten Kröger et al.   Cell Host & Microbe

MacA, a Periplasmic Membrane Fusion Protein of the Macrolide Transporter MacAB-TolC, Binds Lipopolysaccharide Core Specifically and with High Affinity

(2013) S. Lu et al.   JOURNAL OF BACTERIOLOGY

The ABC-Type Efflux Pump MacAB Protects Salmonella enterica serovar Typhimurium from Oxidative Stress

(2013) L. M. Bogomolnaya et al.   mBio

Loss of Very-Long O-Antigen Chains Optimizes Capsule-Mediated Immune Evasion by Salmonella enterica Serovar Typhi

(2013) R. W. Crawford et al.   mBio

Invasive Non-Typhoidal Salmonella Typhimurium ST313 Are Not Host-Restricted and Have an Invasive Phenotype in Experimentally Infected Chickens

(2013) Bryony N. Parsons et al.   PLoS Neglected Tropical Diseases

Slc11a1 (Nramp1) impairs growth of Salmonella enterica serovar typhimurium in macrophages via stimulation of lipocalin-2 expression

(2012) Gernot Fritsche et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Invasive non-typhoidal salmonella disease: an emerging and neglected tropical disease in Africa

(2012) Nicholas A Feasey et al.   LANCET

The promoter architectural landscape of the Salmonella PhoP regulon

(2012) Igor Zwir et al.   MOLECULAR MICROBIOLOGY

Intracontinental spread of human invasive Salmonella Typhimurium pathovariants in sub-Saharan Africa

(2012) Chinyere K Okoro et al.   NATURE GENETICS

Genotypic Homogeneity of Multidrug Resistant S. Typhimurium Infecting Distinct Adult and Childhood Susceptibility Groups in Blantyre, Malawi

(2012) Chisomo L. Msefula et al.   PLoS One

Cationic antimicrobial peptides serve as activation signals for the Salmonella Typhimurium PhoPQ and PmrAB regulons in vitro and in vivo

(2012) Susan M. Richards et al.   Frontiers in Cellular and Infection Microbiology

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Engineering multiple genomic deletions in Gram-negative bacteria: analysis of the multi-resistant antibiotic profile of Pseudomonas putida KT2440

(2011) Esteban Martínez-García et al.   ENVIRONMENTAL MICROBIOLOGY

Genome Sequences of Salmonella enterica Serovar Typhimurium, Choleraesuis, Dublin, and Gallinarum Strains of Well- Defined Virulence in Food-Producing Animals

(2011) E. J. Richardson et al.   JOURNAL OF BACTERIOLOGY

Contribution of the PhoP/Q regulon to survival and replication of Salmonella enterica serovar Typhimurium in macrophages

(2011) J. A. Thompson et al.   MICROBIOLOGY-SGM

Malaria impairs resistance to Salmonella through heme- and heme oxygenase–dependent dysfunctional granulocyte mobilization

(2011) Aubrey J Cunnington et al.   NATURE MEDICINE

The Global Burden of NontyphoidalSalmonellaGastroenteritis

(2010) Shannon E. Majowicz et al.   CLINICAL INFECTIOUS DISEASES

Dysregulated Humoral Immunity to Nontyphoidal Salmonella in HIV-Infected African Adults

(2010) C. A. MacLennan et al.   SCIENCE

BLAST+: architecture and applications

(2009) Christiam Camacho et al.   BMC BIOINFORMATICS

Slc11a1 limits intracellular growth ofSalmonella entericasv. Typhimurium by promoting macrophage immune effector functions and impairing bacterial iron acquisition

(2009) Manfred Nairz et al.   CELLULAR MICROBIOLOGY

Epidemic multiple drug resistant Salmonella Typhimurium causing invasive disease in sub-Saharan Africa have a distinct genotype

(2009) R. A. Kingsley et al.   GENOME RESEARCH

Comparative Proteomic Analysis of the PhoP Regulon in Salmonella enterica Serovar Typhi Versus Typhimurium

(2009) Richelle C. Charles et al.   PLoS One

Kinetic control of TolC recruitment by multidrug efflux complexes

(2009) E. B. Tikhonova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nramp1 expression by dendritic cells modulates inflammatory responses duringSalmonellaTyphimurium infection

(2008) Yanet Valdez et al.   CELLULAR MICROBIOLOGY

Nramp1 drives an accelerated inflammatory response duringSalmonella-induced colitis in mice

(2008) Yanet Valdez et al.   CELLULAR MICROBIOLOGY

MacAB Is Involved in the Secretion of Escherichia coli Heat-Stable Enterotoxin II

(2008) H. Yamanaka et al.   JOURNAL OF BACTERIOLOGY

Influence of Slc11a1 (formerly Nramp1) on DSS-induced colitis in mice

(2008) H.-R. Jiang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Growth-phase regulation of lipopolysaccharide O-antigen chain length influences serum resistance in serovars of Salmonella

(2008) D. Bravo et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Simian immunodeficiency virus–induced mucosal interleukin-17 deficiency promotes Salmonella dissemination from the gut

(2008) Manuela Raffatellu et al.   NATURE MEDICINE