SPT6-driven error-free DNA repair safeguards genomic stability of glioblastoma cancer stem-like cells
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
SPT6-driven error-free DNA repair safeguards genomic stability of glioblastoma cancer stem-like cells
Authors
Keywords
-
Journal
Nature Communications
Volume 11, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-09-18
DOI
10.1038/s41467-020-18549-8
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Replication stress drives constitutive activation of the DNA damage response and radioresistance in glioblastoma stem-like cells
- (2018) Ross D Carruthers et al. CANCER RESEARCH
- Spt6 Association with RNA Polymerase II Directs mRNA Turnover During Transcription
- (2018) Raghuvar Dronamraju et al. MOLECULAR CELL
- Targeting glioma stem-like cell survival and chemoresistance through inhibition of lysine-specific histone demethylase KDM2B
- (2018) Mikkel Staberg et al. Molecular Oncology
- Structure of activated transcription complex Pol II–DSIF–PAF–SPT6
- (2018) Seychelle M. Vos et al. NATURE
- Genetic ablation of interacting with Spt6 (Iws1) causes early embryonic lethality
- (2018) Arturo Orlacchio et al. PLoS One
- Deregulated Expression of Mammalian lncRNA through Loss of SPT6 Induces R-Loop Formation, Replication Stress, and Cellular Senescence
- (2018) Takayuki Nojima et al. MOLECULAR CELL
- Chromatin run-on and sequencing maps the transcriptional regulatory landscape of glioblastoma multiforme
- (2018) Tinyi Chu et al. NATURE GENETICS
- The Elongation Factor Spt6 Maintains ESC Pluripotency by Controlling Super-Enhancers and Counteracting Polycomb Proteins
- (2017) A. Hongjun Wang et al. MOLECULAR CELL
- Regulation of repair pathway choice at two-ended DNA double-strand breaks
- (2017) Atsushi Shibata MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- Inhibition of 53BP1 favors homology-dependent DNA repair and increases CRISPR–Cas9 genome-editing efficiency
- (2017) Marella D Canny et al. NATURE BIOTECHNOLOGY
- Activation of WEE1 confers resistance to PI3K inhibition in glioblastoma
- (2017) Shaofang Wu et al. NEURO-ONCOLOGY
- Chaetocin induces apoptosis in human melanoma cells through the generation of reactive oxygen species and the intrinsic mitochondrial pathway, and exerts its anti-tumor activity in vivo
- (2017) Xinming Han et al. PLoS One
- Epigenome Maintenance in Response to DNA Damage
- (2016) Juliette Dabin et al. MOLECULAR CELL
- Enhanced efficacy of combined HDAC and PARP targeting in glioblastoma
- (2016) Rikke D. Rasmussen et al. Molecular Oncology
- Integrative classification of human coding and noncoding genes through RNA metabolism profiles
- (2016) Neelanjan Mukherjee et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- GlioVis data portal for visualization and analysis of brain tumor expression datasets
- (2016) Robert L. Bowman et al. NEURO-ONCOLOGY
- A genome-wide screening uncovers the role of CCAR2 as an antagonist of DNA end resection
- (2016) Ana López-Saavedra et al. Nature Communications
- Chromosomal Instability Affects the Tumorigenicity of Glioblastoma Tumor-Initiating Cells
- (2016) K. M. Godek et al. Cancer Discovery
- Inhibition of histone deacetylases sensitizes glioblastoma cells to lomustine
- (2016) Mikkel Staberg et al. CELLULAR ONCOLOGY
- Integrative classification of human coding and noncoding genes through RNA metabolism profiles
- (2016) Neelanjan Mukherjee et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Mechanisms and Consequences of Double-Strand DNA Break Formation in Chromatin
- (2015) Wendy J. Cannan et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Ectopic expression of RNF168 and 53BP1 increases mutagenic but not physiological non-homologous end joining
- (2015) Dali Zong et al. NUCLEIC ACIDS RESEARCH
- limma powers differential expression analyses for RNA-sequencing and microarray studies
- (2015) Matthew E. Ritchie et al. NUCLEIC ACIDS RESEARCH
- Cell cycle-dependent inhibition of 53BP1 signaling by BRCA1
- (2015) Lin Feng et al. Cell Discovery
- Reconstructing and Reprogramming the Tumor-Propagating Potential of Glioblastoma Stem-like Cells
- (2014) Mario L. Suvà et al. CELL
- 53BP1, BRCA1, and the Choice between Recombination and End Joining at DNA Double-Strand Breaks
- (2014) J. M. Daley et al. MOLECULAR AND CELLULAR BIOLOGY
- Chaetocin antileukemia activity against chronic myelogenous leukemia cells is potentiated by bone marrow stromal factors and overcomes innate imatinib resistance
- (2014) L Truitt et al. Oncogenesis
- Size Does Matter: Why Polyploid Tumor Cells are Critical Drug Targets in the War on Cancer
- (2014) Jermaine Coward et al. Frontiers in Oncology
- 53BP1 Mediates Productive and Mutagenic DNA Repair through Distinct Phosphoprotein Interactions
- (2013) Elsa Callen et al. CELL
- Therapeutic targeting of constitutive PARP activation compromises stem cell phenotype and survival of glioblastoma-initiating cells
- (2013) M Venere et al. CELL DEATH AND DIFFERENTIATION
- The histone chaperone Spt6 coordinates histone H3K27 demethylation and myogenesis
- (2013) A Hongjun Wang et al. EMBO JOURNAL
- Spt6
- (2013) Hiroaki Kato et al. Epigenetics
- A Cell Cycle-Dependent Regulatory Circuit Composed of 53BP1-RIF1 and BRCA1-CtIP Controls DNA Repair Pathway Choice
- (2013) Cristina Escribano-Díaz et al. MOLECULAR CELL
- A feed forward circuit comprising Spt6, Ctk1 and PAF regulates Pol II CTD phosphorylation and transcription elongation
- (2013) R. Dronamraju et al. NUCLEIC ACIDS RESEARCH
- BRCA1-associated exclusion of 53BP1 from DNA damage sites underlies temporal control of DNA repair
- (2012) J. R. Chapman et al. JOURNAL OF CELL SCIENCE
- BRCA1 Functions Independently of Homologous Recombination in DNA Interstrand Crosslink Repair
- (2012) Samuel F. Bunting et al. MOLECULAR CELL
- Spt6 levels are modulated by PAAF1 and proteasome to regulate the HIV-1 LTR
- (2012) Mirai Nakamura et al. Retrovirology
- The DSIF Subunits Spt4 and Spt5 Have Distinct Roles at Various Phases of Immunoglobulin Class Switch Recombination
- (2012) Andre Stanlie et al. PLoS Genetics
- Spt6 Is Required for Heterochromatic Silencing in the Fission Yeast Schizosaccharomyces pombe
- (2011) C. M. Kiely et al. MOLECULAR AND CELLULAR BIOLOGY
- 53BP1 Inhibits Homologous Recombination in Brca1-Deficient Cells by Blocking Resection of DNA Breaks
- (2010) Samuel F. Bunting et al. CELL
- Activation-Induced Cytidine Deaminase Targets DNA at Sites of RNA Polymerase II Stalling by Interaction with Spt5
- (2010) Rushad Pavri et al. CELL
- A Tandem SH2 Domain in Transcription Elongation Factor Spt6 Binds the Phosphorylated RNA Polymerase II C-terminal Repeat Domain (CTD)
- (2010) Mai Sun et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- 53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers
- (2010) Peter Bouwman et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Replication stress and oxidative damage contribute to aberrant constitutive activation of DNA damage signalling in human gliomas
- (2010) J Bartkova et al. ONCOGENE
- The role of BRCA1 in DNA damage response
- (2010) Jiaxue Wu et al. Protein & Cell
- Role of human transcription elongation factor DSIF in the suppression of senescence and apoptosis
- (2009) Toshiharu Komori et al. GENES TO CELLS
- ELDA: Extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays
- (2009) Yifang Hu et al. JOURNAL OF IMMUNOLOGICAL METHODS
- The DNA-damage response in human biology and disease
- (2009) Stephen P. Jackson et al. NATURE
- The Iws1:Spt6:CTD complex controls cotranscriptional mRNA biosynthesis and HYPB/Setd2-mediated histone H3K36 methylation
- (2008) S. M. Yoh et al. GENES & DEVELOPMENT
- Identification of Spt5 Target Genes in Zebrafish Development Reveals Its Dual Activity In Vivo
- (2008) Keerthi Krishnan et al. PLoS One
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now