A feed forward circuit comprising Spt6, Ctk1 and PAF regulates Pol II CTD phosphorylation and transcription elongation

Pol II CTD kinases Bur1 and Kin28 promote Spt5 CTR-independent recruitment of Paf1 complex

(2012) Hongfang Qiu et al.   EMBO JOURNAL

Chromatin and Transcription in Yeast

(2012) Oliver J. Rando et al.   GENETICS

The Spt5 C-Terminal Region Recruits Yeast 3' RNA Cleavage Factor I

(2012) A. Mayer et al.   MOLECULAR AND CELLULAR BIOLOGY

Set2 methylation of histone H3 lysine 36 suppresses histone exchange on transcribed genes

(2012) Swaminathan Venkatesh et al.   NATURE

Chromatin remodelers Isw1 and Chd1 maintain chromatin structure during transcription by preventing histone exchange

(2012) Michaela Smolle et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

CTD Tyrosine Phosphorylation Impairs Termination Factor Recruitment to RNA Polymerase II

(2012) A. Mayer et al.   SCIENCE

Yeast Transcription Elongation Factor Spt5 Associates with RNA Polymerase I and RNA Polymerase II Directly

(2011) Olga V. Viktorovskaya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Replication-independent Histone H3-H4 Chaperones HIR, ASF1, and RTT106 Co-operate to Maintain Promoter Fidelity

(2011) Andrea C. Silva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RNA Polymerase II Carboxyl-terminal Domain Phosphorylation Regulates Protein Stability of the Set2 Methyltransferase and Histone H3 Di- and Trimethylation at Lysine 36

(2011) Stephen M. Fuchs et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structures of the S. cerevisiae Spt6 Core and C-Terminal Tandem SH2 Domain

(2011) Devin Close et al.   JOURNAL OF MOLECULAR BIOLOGY

Spt6 Is Required for Heterochromatic Silencing in the Fission Yeast Schizosaccharomyces pombe

(2011) C. M. Kiely et al.   MOLECULAR AND CELLULAR BIOLOGY

Exposed hydrophobicity is a key determinant of nuclear quality control degradation

(2011) Eric K. Fredrickson et al.   MOLECULAR BIOLOGY OF THE CELL

The Paf1 complex: Platform or player in RNA polymerase II transcription?

(2010) Judith A. Jaehning   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1

(2010) B. Bartkowiak et al.   GENES & DEVELOPMENT

Noncanonical Tandem SH2 Enables Interaction of Elongation Factor Spt6 with RNA Polymerase II

(2010) Marie-Laure Diebold et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Tandem SH2 Domain in Transcription Elongation Factor Spt6 Binds the Phosphorylated RNA Polymerase II C-terminal Repeat Domain (CTD)

(2010) Mai Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Separable Functions of the Fission Yeast Spt5 Carboxyl-Terminal Domain (CTD) in Capping Enzyme Binding and Transcription Elongation Overlap with Those of the RNA Polymerase II CTD

(2010) S. Schneider et al.   MOLECULAR AND CELLULAR BIOLOGY

Control of Chromatin Structure by Spt6: Different Consequences in Coding and Regulatory Regions

(2010) I. Ivanovska et al.   MOLECULAR AND CELLULAR BIOLOGY

Structure and Biological Importance of the Spn1-Spt6 Interaction, and Its Regulatory Role in Nucleosome Binding

(2010) Seth M. McDonald et al.   MOLECULAR CELL

Gene-specific RNA polymerase II phosphorylation and the CTD code

(2010) Hyunmin Kim et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Chemical-genomic dissection of the CTD code

(2010) Joshua R Tietjen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Uniform transitions of the general RNA polymerase II transcription complex

(2010) Andreas Mayer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Interactions between DSIF (DRB sensitivity inducing factor), NELF (negative elongation factor), and the Drosophila RNA polymerase II transcription elongation complex

(2010) A. Missra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spt6 enhances the elongation rate of RNA polymerase II in vivo

(2009) M Behfar Ardehali et al.   EMBO JOURNAL

Phosphorylation of the Yeast Rpb1 C-terminal Domain at Serines 2, 5, and 7

(2009) Minkyu Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histone H2BK123 monoubiquitination is the critical determinant for H3K4 and H3K79 trimethylation by COMPASS and Dot1

(2009) Shima Nakanishi et al.   JOURNAL OF CELL BIOLOGY

Structure and in Vivo Requirement of the Yeast Spt6 SH2 Domain

(2009) Stefan Dengl et al.   JOURNAL OF MOLECULAR BIOLOGY

Phosphorylation of the Transcription Elongation Factor Spt5 by Yeast Bur1 Kinase Stimulates Recruitment of the PAF Complex

(2009) Y. Liu et al.   MOLECULAR AND CELLULAR BIOLOGY

TFIIH Kinase Places Bivalent Marks on the Carboxy-Terminal Domain of RNA Polymerase II

(2009) Md. Sohail Akhtar et al.   MOLECULAR CELL

Phosphorylation of the Pol II CTD by KIN28 Enhances BUR1/BUR2 Recruitment and Ser2 CTD Phosphorylation Near Promoters

(2009) Hongfang Qiu et al.   MOLECULAR CELL

Progression through the RNA Polymerase II CTD Cycle

(2009) Stephen Buratowski   MOLECULAR CELL

Control of transcriptional elongation and cotranscriptional histone modification by the yeast BUR kinase substrate Spt5

(2009) K. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The multi-tasking P-TEFb complex

(2008) Vanessa Brès et al.   CURRENT OPINION IN CELL BIOLOGY

Direct Interactions between the Paf1 Complex and a Cleavage and Polyadenylation Factor Are Revealed by Dissociation of Paf1 from RNA Polymerase II

(2008) Kristen Nordick et al.   EUKARYOTIC CELL

Roles for Ctk1 and Spt6 in Regulating the Different Methylation States of Histone H3 Lysine 36

(2008) M. L. Youdell et al.   MOLECULAR AND CELLULAR BIOLOGY

Chromatin- and Transcription-Related Factors Repress Transcription from within Coding Regions throughout the Saccharomyces cerevisiae Genome

(2008) Vanessa Cheung et al.   PLOS BIOLOGY