Comparative Transcriptome Analysis Reveals the Protective Mechanism of Glycyrrhinic Acid for Deoxynivalenol-Induced Inflammation and Apoptosis in IPEC-J2 Cells

Use of a genetically engineered E. coli overexpressing β-glucuronidase accompanied by glycyrrhizic acid, a natural and anti-inflammatory agent, for directed treatment of colon carcinoma in a mouse model

(2020) Amin Afkhami-Poostchi et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Deoxynivalenol Induces Inflammation in IPEC-J2 Cells by Activating P38 Mapk And Erk1/2

(2020) Hua Zhang et al.   Toxins

ISG15: It's Complicated

(2019) John V. Dzimianski et al.   JOURNAL OF MOLECULAR BIOLOGY

Leaky gut: mechanisms, measurement and clinical implications in humans

(2019) Michael Camilleri   GUT

Progress in Mycotoxins Affecting Intestinal Mucosal Barrier Function

(2019) Zhihua Ren et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Using glycyrrhizic acid to target sumoylation processes during Epstein-Barr virus latency

(2019) Gretchen L. Bentz et al.   PLoS One

Deoxynivalenol induced apoptosis and inflammation of IPEC-J2 cells by promoting ROS production

(2019) Ruifen Kang et al.   ENVIRONMENTAL POLLUTION

β-Conglycinin-Induced Intestinal Porcine Epithelial Cell Damage via the Nuclear Factor κB/Mitogen-Activated Protein Kinase Signaling Pathway

(2019) Chenglu Peng et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Proteomic responses to oxidative damage in meat from ducks exposed to heat stress

(2019) Jun He et al.   FOOD CHEMISTRY

Hepatoprotective effect of different combinations of 18α-and 18β-Glycyrrhizic acid against CCl4-induced liver injury in rats

(2019) Xiaowei Huo et al.   BIOMEDICINE & PHARMACOTHERAPY

Schisandrin A protects intestinal epithelial cells from deoxynivalenol-induced cytotoxicity, oxidative damage and inflammation

(2019) Murphy L. Y. Wan et al.   Scientific Reports

Mung Bean Protein Hydrolysates Protect Mouse Liver Cell Line Nctc-1469 Cell from Hydrogen Peroxide-Induced Cell Injury

(2019) Jianhua Xie et al.   Foods

Application of Traditional Chinese Herbal Medicine By-products as Dietary Feed Supplements and Antibiotic Replacements in Animal Production

(2018) Abedin Abdallah et al.   CURRENT DRUG METABOLISM

A guide to chemokines and their receptors

(2018) Catherine E. Hughes et al.   FEBS Journal

Deoxynivalenol, gut microbiota and immunotoxicity: A potential approach?

(2018) Yuxiao Liao et al.   FOOD AND CHEMICAL TOXICOLOGY

DACH1 antagonizes CXCL8 to repress tumorigenesis of lung adenocarcinoma and improve prognosis

(2018) Qian Liu et al.   Journal of Hematology & Oncology

Cytokine Tuning of Intestinal Epithelial Function

(2018) Caroline Andrews et al.   Frontiers in Immunology

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

(2018) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Deoxynivalenol Affects Cell Metabolism and Increases Protein Biosynthesis in Intestinal Porcine Epithelial Cells (IPEC-J2): DON Increases Protein Biosynthesis

(2018) Constanze Nossol et al.   Toxins

Glycyrrhizic acid suppresses inflammation and reduces the increased glucose levels induced by the combination of Porphyromonas gulae and ligature placement in diabetic model mice

(2018) Keiichi Akutagawa et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Combined effects of deoxynivalenol and zearalenone on oxidative injury and apoptosis in porcine splenic lymphocytes in vitro

(2017) Zhihua Ren et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Glycyrrhizic acid induces human MDA-MB-231 breast cancer cell death and autophagy via the ROS-mitochondrial pathway

(2017) Shu-Chuan Lin et al.   ONCOLOGY REPORTS

The Food Contaminants Nivalenol and Deoxynivalenol Induce Inflammation in Intestinal Epithelial Cells by Regulating Reactive Oxygen Species Release

(2017) Simona Adesso et al.   Nutrients

Antioxidant agents against trichothecenes: new hints for oxidative stress treatment

(2017) Qinghua Wu et al.   Oncotarget

Co-exposure to low doses of the food contaminants deoxynivalenol and nivalenol has a synergistic inflammatory effect on intestinal explants

(2016) Imourana Alassane-Kpembi et al.   ARCHIVES OF TOXICOLOGY

Early Activation of MAPK p44/42 Is Partially Involved in DON-Induced Disruption of the Intestinal Barrier Function and Tight Junction Network

(2016) Alexandra Springler et al.   Toxins

Phosphoproteome Analysis Reveals the Molecular Mechanisms Underlying Deoxynivalenol-Induced Intestinal Toxicity in IPEC-J2 Cells

(2016) Zhi-Qi Zhang et al.   Toxins

Fate of deoxynivalenol and deoxynivalenol-3-glucoside during cereal-based thermal food processing: a review study

(2016) Qinghua Wu et al.   Mycotoxin Research

Autophagy protects intestinal epithelial Cells against Deoxynivalenol toxicity by alleviating oxidative stress via IKK signaling pathway

(2015) Yulong Tang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Signaling pathway of MAPK/ERK in cell proliferation, differentiation, migration, senescence and apoptosis

(2015) Yu Sun et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

HISAT: a fast spliced aligner with low memory requirements

(2015) Daehwan Kim et al.   NATURE METHODS

Chemokines and Chemokine Receptors: Positioning Cells for Host Defense and Immunity

(2014) Jason W. Griffith et al.   Annual Review of Immunology

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Effect of Astragalus polysaccharides on expression of TNF-α, IL-1β and NFATc4 in a rat model of experimental colitis

(2014) Min Yang et al.   CYTOKINE

A study of Semen Strychni-induced renal injury and herb–herb interaction of Radix Glycyrrhizae extract and/or Rhizoma Ligustici extract on the comparative toxicokinetics of strychnine and brucine in rats

(2014) Liqiang Gu et al.   FOOD AND CHEMICAL TOXICOLOGY

Impacts of the feed contaminant deoxynivalenol on the intestine of monogastric animals: poultry and swine

(2014) Khaled Ghareeb et al.   JOURNAL OF APPLIED TOXICOLOGY

The Intestinal Crypt, A Prototype Stem Cell Compartment

(2013) Hans Clevers   CELL

Targeting CCL5 in inflammation

(2013) Rafael Elias Marques et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

MAPKs and Signal Transduction in the Control of Gastrointestinal Epithelial Cell Proliferation and Differentiation

(2013) Luciana Osaki et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Anti-rotaviral effects of Glycyrrhiza uralensis extract in piglets with rotavirus diarrhea

(2012) Mia Madel Alfajaro et al.   Virology Journal

Effects of dietary supplementation of Chinese medicinal herbs on polymorphonuclear neutrophil immune activity and small intestinal morphology in weanling pigs

(2011) C. W. Huang et al.   JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION

Porcine IPEC-J2 intestinal epithelial cells in microbiological investigations

(2011) Amanda J. Brosnahan et al.   VETERINARY MICROBIOLOGY

Anti-apoptosis and cell survival: A review

(2010) Liam Portt et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Lutein protects HT-29 cells against Deoxynivalenol-induced oxidative stress and apoptosis: Prevention of NF-κB nuclear localization and down regulation of NF-κB and Cyclo-Oxygenase – 2 expression

(2010) Rajashree Krishnaswamy et al.   FREE RADICAL BIOLOGY AND MEDICINE

Deoxynivalenol Impairs Porcine Intestinal Barrier Function and Decreases the Protein Expression of Claudin-4 through a Mitogen-Activated Protein Kinase-Dependent Mechanism

(2010) Philippe Pinton et al.   JOURNAL OF NUTRITION

Development of a pig jejunal explant culture for studying the gastrointestinal toxicity of the mycotoxin deoxynivalenol: Histopathological analysis

(2009) Martine Kolf-Clauw et al.   TOXICOLOGY IN VITRO

The role of oxidative stress in deoxynivalenol-induced DNA damage in HepG2 cells

(2009) Xiaoou Zhang et al.   TOXICON