Epigenetic programming underpins B cell dysfunction in human SLE

Constitutively Bound EGFR–Mediated Tyrosine Phosphorylation of TLR9 Is Required for Its Ability To Signal

(2018) Manoj Veleeparambil et al.   JOURNAL OF IMMUNOLOGY

Regulation of age-associated B cells by IRF5 in systemic autoimmunity

(2018) Michela Manni et al.   NATURE IMMUNOLOGY

Plasma cell differentiation is controlled by multiple cell division-coupled epigenetic programs

(2018) Christopher D. Scharer et al.   Nature Communications

B cell activation and plasma cell differentiation are inhibited by de novo DNA methylation

(2018) Benjamin G. Barwick et al.   Nature Communications

Progressive Upregulation of Oxidative Metabolism Facilitates Plasmablast Differentiation to a T-Independent Antigen

(2018) Madeline J. Price et al.   Cell Reports

Twin DNA Methylation Profiling Reveals Flare-Dependent Interferon Signature and B Cell Promoter Hypermethylation in Systemic Lupus Erythematosus

(2018) Constance J. Ulff-Møller et al.   Arthritis & Rheumatology

Distinct Effector B Cells Induced by Unregulated Toll-like Receptor 7 Contribute to Pathogenic Responses in Systemic Lupus Erythematosus

(2018) Scott A. Jenks et al.   IMMUNITY

EPSTI1 polymorphisms are associated with systemic lupus erythematosus

(2017) Ji-Su Mo et al.   Genes & Genomics

Age-Associated B Cells Express a Diverse Repertoire of VHand Vκ Genes with Somatic Hypermutation

(2017) Lisa M. Russell Knode et al.   JOURNAL OF IMMUNOLOGY

The Orphan Nuclear Receptor NR4A3 Is Involved in the Function of Dendritic Cells

(2017) Masanori Nagaoka et al.   JOURNAL OF IMMUNOLOGY

Transancestral mapping and genetic load in systemic lupus erythematosus

(2017) Carl D. Langefeld et al.   Nature Communications

CARMA1- and MyD88-dependent activation of Jun/ATF-type AP-1 complexes is a hallmark of ABC diffuse large B-cell lymphomas

(2016) M. Juilland et al.   BLOOD

Personalized Immunomonitoring Uncovers Molecular Networks that Stratify Lupus Patients

(2016) Romain Banchereau et al.   CELL

Endogenous Nur77 Is a Specific Indicator of Antigen Receptor Signaling in Human T and B Cells

(2016) Judith F. Ashouri et al.   JOURNAL OF IMMUNOLOGY

Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution

(2016) M Ryan Corces et al.   NATURE GENETICS

Plasma cell differentiation is coupled to division-dependent DNA hypomethylation and gene regulation

(2016) Benjamin G Barwick et al.   NATURE IMMUNOLOGY

ATAC-seq on biobanked specimens defines a unique chromatin accessibility structure in naïve SLE B cells

(2016) Christopher D. Scharer et al.   Scientific Reports

EGFR kinase activity is required for TLR4 signaling and the septic shock response

(2015) S. Chattopadhyay et al.   EMBO REPORTS

Whole-genome fingerprint of the DNA methylome during human B cell differentiation

(2015) Marta Kulis et al.   NATURE GENETICS

Diversity, cellular origin and autoreactivity of antibody-secreting cell population expansions in acute systemic lupus erythematosus

(2015) Christopher M Tipton et al.   NATURE IMMUNOLOGY

Early Growth Response-1 Plays a Non-redundant Role in the Differentiation of B Cells into Plasma Cells

(2015) Yeon-Kyung Oh et al.   Immune Network

bwtool: a tool for bigWig files

(2014) Andy Pohl et al.   BIOINFORMATICS

Lipopolysaccharide-Induced Expression of Matrix Metalloproteinases in Human Monocytes Is Suppressed by IFN-  via Superinduction of ATF-3 and Suppression of AP-1

(2014) H. H. Ho et al.   JOURNAL OF IMMUNOLOGY

Early Growth Response Genes Regulate B Cell Development, Proliferation, and Immune Response

(2014) M. Gururajan et al.   JOURNAL OF IMMUNOLOGY

A Bayesian hierarchical model to detect differentially methylated loci from single nucleotide resolution sequencing data

(2014) Hao Feng et al.   NUCLEIC ACIDS RESEARCH

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

TRAF5 Negatively Regulates TLR Signaling in B Lymphocytes

(2013) C. M. Buchta et al.   JOURNAL OF IMMUNOLOGY

Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position

(2013) Jason D Buenrostro et al.   NATURE METHODS

Identification of epithelial stromal interaction 1 as a novel effector downstream of Krüppel-like factor 8 in breast cancer invasion and metastasis

(2013) T Li et al.   ONCOGENE

Software for Computing and Annotating Genomic Ranges

(2013) Michael Lawrence et al.   PLoS Computational Biology

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia

(2012) S. G. Landt et al.   GENOME RESEARCH

ZBTB32 Is an Early Repressor of the CIITA and MHC Class II Gene Expression during B Cell Differentiation to Plasma Cells

(2012) H. S. Yoon et al.   JOURNAL OF IMMUNOLOGY

Type I IFN Receptor and the B Cell Antigen Receptor Regulate TLR7 Responses via Distinct Molecular Mechanisms

(2012) J. S. Poovassery et al.   JOURNAL OF IMMUNOLOGY

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

A Genomic Regulatory Element That Directs Assembly and Function of Immune-Specific AP-1-IRF Complexes

(2012) E. Glasmacher et al.   SCIENCE

Bismark: a flexible aligner and methylation caller for Bisulfite-Seq applications

(2011) Felix Krueger et al.   BIOINFORMATICS

A B-cell subset uniquely responsive to innate stimuli accumulates in aged mice

(2011) Y. Hao et al.   BLOOD

Toll-like receptor 7 (TLR7)-driven accumulation of a novel CD11c+ B-cell population is important for the development of autoimmunity

(2011) A. V. Rubtsov et al.   BLOOD

REVIGO Summarizes and Visualizes Long Lists of Gene Ontology Terms

(2011) Fran Supek et al.   PLoS One

Differential Genetic Associations for Systemic Lupus Erythematosus Based on Anti–dsDNA Autoantibody Production

(2011) Sharon A. Chung et al.   PLoS Genetics

A framework for oligonucleotide microarray preprocessing

(2010) Benilton S. Carvalho et al.   BIOINFORMATICS

Regulatory polymorphisms in EGR2 are associated with susceptibility to systemic lupus erythematosus

(2010) K. Myouzen et al.   HUMAN MOLECULAR GENETICS

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

Early growth response transcription factors and the modulation of immune response

(2009) Diana Gómez-Martín et al.   AUTOIMMUNITY REVIEWS

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus

(2009) B. M. Javierre et al.   GENOME RESEARCH

The genetics and epigenetics of autoimmune diseases

(2009) Anura Hewagama et al.   JOURNAL OF AUTOIMMUNITY

Novel Human Transitional B Cell Populations Revealed by B Cell Depletion Therapy

(2009) Arumugam Palanichamy et al.   JOURNAL OF IMMUNOLOGY

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

Phenotypic and functional heterogeneity of human memory B cells

(2008) Iñaki Sanz et al.   SEMINARS IN IMMUNOLOGY

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY