Understanding B-cell activation and autoantibody repertoire selection in systemic lupus erythematosus: A B-cell immunomics approach

Functional interrogation and mining of natively paired human VH:VL antibody repertoires

(2018) Bo Wang et al.   NATURE BIOTECHNOLOGY

An atlas of B-cell clonal distribution in the human body

(2017) Wenzhao Meng et al.   NATURE BIOTECHNOLOGY

Massively parallel digital transcriptional profiling of single cells

(2017) Grace X. Y. Zheng et al.   Nature Communications

Clonal redemption of autoantibodies by somatic hypermutation away from self-reactivity during human immunization

(2016) Joanne H. Reed et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: IL-4, IL-21, and IFN-γ Interact To Govern T-bet and CD11c Expression in TLR-Activated B Cells

(2016) Martin S. Naradikian et al.   JOURNAL OF IMMUNOLOGY

Molecular-level analysis of the serum antibody repertoire in young adults before and after seasonal influenza vaccination

(2016) Jiwon Lee et al.   NATURE MEDICINE

Ultra-high-throughput sequencing of the immune receptor repertoire from millions of lymphocytes

(2016) Jonathan R McDaniel et al.   Nature Protocols

New insights into the immunopathogenesis of systemic lupus erythematosus

(2016) George C. Tsokos et al.   Nature Reviews Rheumatology

Identification of significant B cell associations with undetected observations using a Tobit model

(2016) Tian Chen et al.   Statistics and Its Interface

Checkpoints for Autoreactive B Cells in the Peripheral Blood of Lupus Patients Assessed by Flow Cytometry

(2016) Susan Malkiel et al.   Arthritis & Rheumatology

ATAC-seq on biobanked specimens defines a unique chromatin accessibility structure in naïve SLE B cells

(2016) Christopher D. Scharer et al.   Scientific Reports

Serology in the 21st century: the molecular-level analysis of the serum antibody repertoire

(2015) Yariv Wine et al.   CURRENT OPINION IN IMMUNOLOGY

The end of gating? An introduction to automated analysis of high dimensional cytometry data

(2015) Florian Mair et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Long-Lived Plasma Cells Are Contained within the CD19−CD38hiCD138+ Subset in Human Bone Marrow

(2015) Jessica L. Halliley et al.   IMMUNITY

Age-Associated B Cells: A T-bet–Dependent Effector with Roles in Protective and Pathogenic Immunity

(2015) Kira Rubtsova et al.   JOURNAL OF IMMUNOLOGY

Diversity, cellular origin and autoreactivity of antibody-secreting cell population expansions in acute systemic lupus erythematosus

(2015) Christopher M Tipton et al.   NATURE IMMUNOLOGY

Light chain editors of anti-DNA receptors in human B cells

(2014) Olga Kalinina et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Expanded Population of Activated Antigen-Engaged Cells within the Naive B Cell Compartment of Patients with Systemic Lupus Erythematosus

(2014) N.-H. Chang et al.   JOURNAL OF IMMUNOLOGY

B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodes

(2014) J. N. H. Stern et al.   Science Translational Medicine

Molecular Basis of 9G4 B Cell Autoreactivity in Human Systemic Lupus Erythematosus

(2013) C. Richardson et al.   JOURNAL OF IMMUNOLOGY

The pathogenesis of systemic lupus erythematosus—an update

(2012) Jinyoung Choi et al.   CURRENT OPINION IN IMMUNOLOGY

Developing connections amongst key cytokines and dysregulated germinal centers in autoimmunity

(2012) Rebecca A Sweet et al.   CURRENT OPINION IN IMMUNOLOGY

Ultrasensitive Clinical Enumeration of Rare Cells ex Vivo Using a Micro-Hall Detector

(2012) D. Issadore et al.   Science Translational Medicine

Advances in Human B Cell Phenotypic Profiling

(2012) Denise A. Kaminski et al.   Frontiers in Immunology

Circulating Human Antibody-Secreting Cells during Vaccinations and Respiratory Viral Infections Are Characterized by High Specificity and Lack of Bystander Effect

(2011) F. E.-H. Lee et al.   JOURNAL OF IMMUNOLOGY

Differential regulation of self-reactivity discriminates between IgG+ human circulating memory B cells and bone marrow plasma cells

(2011) J. F. Scheid et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms of B cell autoimmunity in SLE

(2011) Thomas Dörner et al.   ARTHRITIS RESEARCH & THERAPY

Elucidation of seventeen human peripheral blood B-cell subsets and quantification of the tetanus response using a density-based method for the automated identification of cell populations in multidimensional flow cytometry data

(2010) Yu Qian et al.   CYTOMETRY PART B-CLINICAL CYTOMETRY

The Ubiquitin Modifying Enzyme A20 Restricts B Cell Survival and Prevents Autoimmunity

(2010) Rita M. Tavares et al.   IMMUNITY

In Situ B Cell-Mediated Immune Responses and Tubulointerstitial Inflammation in Human Lupus Nephritis

(2010) A. Chang et al.   JOURNAL OF IMMUNOLOGY

Rare genes for autoimmunity—the new kids on the block

(2010) Anne B. Satterthwaite et al.   Nature Reviews Rheumatology

Mass Cytometry: Technique for Real Time Single Cell Multitarget Immunoassay Based on Inductively Coupled Plasma Time-of-Flight Mass Spectrometry

(2009) Dmitry R. Bandura et al.   ANALYTICAL CHEMISTRY

B Cells and Immunological Tolerance

(2009) Nataly Manjarrez-Orduño et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Rapid cloning of high-affinity human monoclonal antibodies against influenza virus

(2008) Jens Wrammert et al.   NATURE

Systemic Lupus Erythematosus

(2008) Anisur Rahman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Autoreactive IgG memory antibodies in patients with systemic lupus erythematosus arise from nonreactive and polyreactive precursors

(2008) B. Mietzner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA