- Home
- Publications
- Publication Search
- Publication Details
Title
Host–microbiota maladaptation in colorectal cancer
Authors
Keywords
-
Journal
NATURE
Volume 585, Issue 7826, Pages 509-517
Publisher
Springer Science and Business Media LLC
Online
2020-09-24
DOI
10.1038/s41586-020-2729-3
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Autophagy of Intestinal Epithelial Cells Inhibits Colorectal Carcinogenesis Induced by Colibactin-Producing Escherichia coli in Apc Mice
- (2020) Cécily Lucas et al. GASTROENTEROLOGY
- Expression of Free Fatty Acid Receptor 2 by Dendritic Cells Prevents Their Expression of Interleukin 27 and Is Required for Maintenance of Mucosal Barrier and Immune Response Against Colorectal Tumors in Mice
- (2020) Sydney Lavoie et al. GASTROENTEROLOGY
- Association Between Sulfur-Metabolizing Bacterial Communities in Stool and Risk of Distal Colorectal Cancer in Men
- (2020) Long H. Nguyen et al. GASTROENTEROLOGY
- Tumor Immunology and Tumor Evolution: Intertwined Histories
- (2020) Jérôme Galon et al. IMMUNITY
- High‐fat diet‐induced dysbiosis mediates MCP‐1/CCR2 axis‐dependent M2 macrophage polarization and promotes intestinal adenoma‐adenocarcinoma sequence
- (2020) Tianyu Liu et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Host responses to mucosal biofilms in the lung and gut
- (2020) Jada C. Domingue et al. Mucosal Immunology
- Mutational signature in colorectal cancer caused by genotoxic pks+ E. coli
- (2020) Cayetano Pleguezuelos-Manzano et al. NATURE
- Distinct microbial and immune niches of the human colon
- (2020) Kylie R. James et al. NATURE IMMUNOLOGY
- Cell-type-specific signaling networks in heterocellular organoids
- (2020) Xiao Qin et al. NATURE METHODS
- Microbiome in Colorectal Cancer: How to Get from Meta-omics to Mechanism?
- (2020) Dominik Ternes et al. TRENDS IN MICROBIOLOGY
- Endogenous murine microbiota member Faecalibaculum rodentium and its human homologue protect from intestinal tumour growth
- (2020) Elena Zagato et al. Nature Microbiology
- Multi-omic profiling reveals associations between the gut mucosal microbiome, the metabolome, and host DNA methylation associated gene expression in patients with colorectal cancer
- (2020) Qing Wang et al. BMC MICROBIOLOGY
- Structure of the Mucosal and Stool Microbiome in Lynch Syndrome
- (2020) Yan Yan et al. Cell Host & Microbe
- The interleukin 22 pathway interacts with mutant KRAS to promote poor prognosis in colon cancer
- (2020) Sarah McCuaig et al. CLINICAL CANCER RESEARCH
- Full-repertoire comparison of the microscopic objects composing the human gut microbiome with sequenced and cultured communities
- (2020) Edmond Kuete Yimagou et al. JOURNAL OF MICROBIOLOGY
- Limiting oxidative DNA damage reduces microbe-induced colitis-associated colorectal cancer
- (2020) Thergiory Irrazabal et al. Nature Communications
- TGF-β signaling in Th17 cells promotes IL-22 production and colitis-associated colon cancer
- (2020) Laura Garcia Perez et al. Nature Communications
- Colorectal cancer-associated anaerobic bacteria proliferate in tumor spheroids and alter the microenvironment
- (2020) Stephen H. Kasper et al. Scientific Reports
- Gut Microbiota Modulate CD8 T Cell Responses to Influence Colitis-Associated Tumorigenesis
- (2020) Amy I. Yu et al. Cell Reports
- Metaproteomics characterizes human gut microbiome function in colorectal cancer
- (2020) Shuping Long et al. npj Biofilms and Microbiomes
- Altered Gut Archaea Composition and Interaction with Bacteria are Associated with Colorectal Cancer
- (2020) Olabisi Oluwabukola Coker et al. GASTROENTEROLOGY
- Gut microbiota modulation: a novel strategy for prevention and treatment of colorectal cancer
- (2020) Winnie Fong et al. ONCOGENE
- Cell-Type-Specific Responses to Interleukin-1 Control Microbial Invasion and Tumor-Elicited Inflammation in Colorectal Cancer
- (2019) Oxana Dmitrieva-Posocco et al. IMMUNITY
- Controlling Epithelial Polarity: A Human Enteroid Model for Host-Pathogen Interactions
- (2019) Julia Y. Co et al. Cell Reports
- Interleukin-22 protects intestinal stem cells against genotoxic stress
- (2019) Konrad Gronke et al. NATURE
- Human colon mucosal biofilms from healthy or colon cancer hosts are carcinogenic
- (2019) Sarah Tomkovich et al. JOURNAL OF CLINICAL INVESTIGATION
- The Short Chain Fatty Acid Butyrate Imprints an Antimicrobial Program in Macrophages
- (2019) Julie Schulthess et al. IMMUNITY
- Microbiome and colorectal cancer: Roles in carcinogenesis and clinical potential
- (2019) Ester Saus et al. MOLECULAR ASPECTS OF MEDICINE
- Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases
- (2019) Jason Lloyd-Price et al. NATURE
- Meta-analysis of fecal metagenomes reveals global microbial signatures that are specific for colorectal cancer
- (2019) Jakob Wirbel et al. NATURE MEDICINE
- Integrated In Vitro and In Silico Modeling Delineates the Molecular Effects of a Synbiotic Regimen on Colorectal-Cancer-Derived Cells
- (2019) Kacy Greenhalgh et al. Cell Reports
- A complex human gut microbiome cultured in an anaerobic intestine-on-a-chip
- (2019) Sasan Jalili-Firoozinezhad et al. Nature Biomedical Engineering
- Editing of the gut microbiota reduces carcinogenesis in mouse models of colitis-associated colorectal cancer
- (2019) Wenhan Zhu et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Metagenomic and metabolomic analyses reveal distinct stage-specific phenotypes of the gut microbiota in colorectal cancer
- (2019) Shinichi Yachida et al. NATURE MEDICINE
- Microbial genes and pathways in inflammatory bowel disease
- (2019) Melanie Schirmer et al. NATURE REVIEWS MICROBIOLOGY
- The gut microbiota and colon cancer
- (2019) Wendy S. Garrett SCIENCE
- Laboratory mice born to wild mice have natural microbiota and model human immune responses
- (2019) Stephan P. Rosshart et al. SCIENCE
- Cancer modeling meets human organoid technology
- (2019) David Tuveson et al. SCIENCE
- Phage-guided modulation of the gut microbiota of mouse models of colorectal cancer augments their responses to chemotherapy
- (2019) Di-Wei Zheng et al. Nature Biomedical Engineering
- Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis
- (2019) Rene Jackstadt et al. CANCER CELL
- Global burden of colorectal cancer: emerging trends, risk factors and prevention strategies
- (2019) NaNa Keum et al. Nature Reviews Gastroenterology & Hepatology
- Gut microbiota in colorectal cancer: mechanisms of action and clinical applications
- (2019) Sunny H. Wong et al. Nature Reviews Gastroenterology & Hepatology
- Peptostreptococcus anaerobius promotes colorectal carcinogenesis and modulates tumour immunity
- (2019) Xiaohang Long et al. Nature Microbiology
- Western Diet Promotes Intestinal Colonization by Collagenolytic Microbes and Promotes Tumor Formation Following Colorectal Surgery
- (2019) Sara Gaines et al. GASTROENTEROLOGY
- Colorectal cancer-associated microbiota contributes to oncogenic epigenetic signatures
- (2019) Iradj Sobhani et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Clostridium butyricum, a butyrate-producing probiotic, inhibits intestinal tumor development through modulating Wnt signaling and gut microbiota
- (2019) Danfeng Chen et al. CANCER LETTERS
- T Cell Dysfunction in Cancer
- (2018) Daniela S. Thommen et al. CANCER CELL
- The Intestinal Microbiota in Colorectal Cancer
- (2018) Herbert Tilg et al. CANCER CELL
- Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells
- (2018) Liam Chung et al. Cell Host & Microbe
- A catch-22: Interleukin-22 and cancer
- (2018) Pedro Hernandez et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Alterations in Enteric Virome Are Associated With Colorectal Cancer and Survival Outcomes
- (2018) Geicho Nakatsu et al. GASTROENTEROLOGY
- Gut microbiota modulate T cell trafficking into human colorectal cancer
- (2018) Eleonora Cremonesi et al. GUT
- A surgical orthotopic organoid transplantation approach in mice to visualize and study colorectal cancer progression
- (2018) Arianna Fumagalli et al. Nature Protocols
- The path to metastatic mouse models of colorectal cancer
- (2018) Gabriele Romano et al. ONCOGENE
- Patients with familial adenomatous polyposis harbor colonic biofilms containing tumorigenic bacteria
- (2018) Christine M. Dejea et al. SCIENCE
- Human Gut Microbiome: Function Matters
- (2018) Anna Heintz-Buschart et al. TRENDS IN MICROBIOLOGY
- Structural Remodeling of the Human Colonic Mesenchyme in Inflammatory Bowel Disease
- (2018) James Kinchen et al. CELL
- The Environmental Sensor AHR Protects from Inflammatory Damage by Maintaining Intestinal Stem Cell Homeostasis and Barrier Integrity
- (2018) Amina Metidji et al. IMMUNITY
- SYK-CARD9 Signaling Axis Promotes Gut Fungi-Mediated Inflammasome Activation to Restrict Colitis and Colon Cancer
- (2018) Ankit Malik et al. IMMUNITY
- Advances in organ-on-a-chip engineering
- (2018) Boyang Zhang et al. Nature Reviews Materials
- Streptococcus gallolyticus conspires myeloid cells to promote tumorigenesis of inflammatory bowel disease
- (2018) Yucheng Zhang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Enteric fungal microbiota dysbiosis and ecological alterations in colorectal cancer
- (2018) Olabisi Oluwabukola Coker et al. GUT
- Campylobacter jejuni promotes colorectal tumorigenesis through the action of cytolethal distending toxin
- (2018) Zhen He et al. GUT
- Tales from the crypt: new insights into intestinal stem cells
- (2018) Helmuth Gehart et al. Nature Reviews Gastroenterology & Hepatology
- Mouse Microbiota Models: Comparing Germ-Free Mice and Antibiotics Treatment as Tools for Modifying Gut Bacteria
- (2018) Elizabeth A. Kennedy et al. Frontiers in Physiology
- Gavage of Fecal Samples From Patients With Colorectal Cancer Promotes Intestinal Carcinogenesis in Germ-Free and Conventional Mice
- (2017) Sunny H. Wong et al. GASTROENTEROLOGY
- Analysis ofFusobacteriumpersistence and antibiotic response in colorectal cancer
- (2017) Susan Bullman et al. SCIENCE
- NLRP6 Protects Il10 −/− Mice from Colitis by Limiting Colonization of Akkermansia muciniphila
- (2017) Sergey S. Seregin et al. Cell Reports
- High-resolution bacterial 16S rRNA gene profile meta-analysis and biofilm status reveal common colorectal cancer consortia
- (2017) Julia L. Drewes et al. npj Biofilms and Microbiomes
- The Colonic Crypt Protects Stem Cells from Microbiota-Derived Metabolites
- (2016) Gerard E. Kaiko et al. CELL
- A Dietary Fiber-Deprived Gut Microbiota Degrades the Colonic Mucus Barrier and Enhances Pathogen Susceptibility
- (2016) Mahesh S. Desai et al. CELL
- Lipocalin 2 Protects from Inflammation and Tumorigenesis Associated with Gut Microbiota Alterations
- (2016) Alexander R. Moschen et al. Cell Host & Microbe
- IL-33 regulates the IgA-microbiota axis to restrain IL-1α–dependent colitis and tumorigenesis
- (2016) Ankit Malik et al. JOURNAL OF CLINICAL INVESTIGATION
- The myeloid immune signature of enterotoxigenic Bacteroides fragilis-induced murine colon tumorigenesis
- (2016) E Thiele Orberg et al. Mucosal Immunology
- Reparative inflammation takes charge of tissue regeneration
- (2016) Michael Karin et al. NATURE
- From tumour heterogeneity to advances in precision treatment of colorectal cancer
- (2016) Cornelis J. A. Punt et al. Nature Reviews Clinical Oncology
- The healthy human microbiome
- (2016) Jason Lloyd-Price et al. Genome Medicine
- Dysbiosis is not an answer
- (2016) Scott W. Olesen et al. Nature Microbiology
- Epithelial IL-18 Equilibrium Controls Barrier Function in Colitis
- (2015) Roni Nowarski et al. CELL
- Small-molecule inhibitors prevent the genotoxic and protumoural effects induced by colibactin-producing bacteria
- (2015) Antony Cougnoux et al. GUT
- Binding of the Fap2 Protein of Fusobacterium nucleatum to Human Inhibitory Receptor TIGIT Protects Tumors from Immune Cell Attack
- (2015) Chamutal Gur et al. IMMUNITY
- Substantial contribution of extrinsic risk factors to cancer development
- (2015) Song Wu et al. NATURE
- Intestinal inhibition of Atg7 prevents tumour initiation through a microbiome-influenced immune response and suppresses tumour growth
- (2015) Jonathan Lévy et al. NATURE CELL BIOLOGY
- Gut Microbial Metabolism Drives Transformation of Msh2-Deficient Colon Epithelial Cells
- (2014) Antoaneta Belcheva et al. CELL
- Role of the Microbiota in Immunity and Inflammation
- (2014) Yasmine Belkaid et al. CELL
- Bile acids and the gut microbiome
- (2014) Jason M. Ridlon et al. CURRENT OPINION IN GASTROENTEROLOGY
- Commensal bacteria drive endogenous transformation and tumour stem cell marker expression through a bystander effect
- (2014) Xingmin Wang et al. GUT
- Bacterial genotoxin colibactin promotes colon tumour growth by inducing a senescence-associated secretory phenotype
- (2014) Antony Cougnoux et al. GUT
- γδT17 Cells Promote the Accumulation and Expansion of Myeloid-Derived Suppressor Cells in Human Colorectal Cancer
- (2014) Pin Wu et al. IMMUNITY
- Activation of Gpr109a, Receptor for Niacin and the Commensal Metabolite Butyrate, Suppresses Colonic Inflammation and Carcinogenesis
- (2014) Nagendra Singh et al. IMMUNITY
- The gut microbiota, bacterial metabolites and colorectal cancer
- (2014) Petra Louis et al. NATURE REVIEWS MICROBIOLOGY
- The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition
- (2014) Pamela V. Chang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Microbiota organization is a distinct feature of proximal colorectal cancers
- (2014) Christine M. Dejea et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Microbial genomic analysis reveals the essential role of inflammation in bacteria-induced colorectal cancer
- (2014) Janelle C. Arthur et al. Nature Communications
- A Gnotobiotic Mouse Model Demonstrates That Dietary Fiber Protects against Colorectal Tumorigenesis in a Microbiota- and Butyrate-Dependent Manner
- (2014) D. R. Donohoe et al. Cancer Discovery
- Adenomatous Polyps Are Driven by Microbe-Instigated Focal Inflammation and Are Controlled by IL-10-Producing T Cells
- (2013) K. L. Dennis et al. CANCER RESEARCH
- Gut Microbiota Protects against Gastrointestinal Tumorigenesis Caused by Epithelial Injury
- (2013) Y. Zhan et al. CANCER RESEARCH
- Fusobacterium nucleatum Potentiates Intestinal Tumorigenesis and Modulates the Tumor-Immune Microenvironment
- (2013) Aleksandar D. Kostic et al. Cell Host & Microbe
- Tryptophan Catabolites from Microbiota Engage Aryl Hydrocarbon Receptor and Balance Mucosal Reactivity via Interleukin-22
- (2013) Teresa Zelante et al. IMMUNITY
- Innate lymphoid cells sustain colon cancer through production of interleukin-22 in a mouse model
- (2013) Stefanie Kirchberger et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Microbiota-induced activation of epithelial IL-6 signaling links inflammasome-driven inflammation with transmissible cancer
- (2013) B. Hu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Gut Microbiome Modulates Colon Tumorigenesis
- (2013) J. P. Zackular et al. mBio
- Risk of Colorectal Cancer in Patients With Ulcerative Colitis: A Meta-analysis of Population-Based Cohort Studies
- (2012) Tine Jess et al. Clinical Gastroenterology and Hepatology
- Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth
- (2012) Sergei I. Grivennikov et al. NATURE
- Intestinal Inflammation Targets Cancer-Inducing Activity of the Microbiota
- (2012) J. C. Arthur et al. SCIENCE
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Polyamine catabolism contributes to enterotoxigenic Bacteroides fragilis-induced colon tumorigenesis
- (2011) A. C. Goodwin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Homeostasis and Inflammation in the Intestine
- (2010) Wendy S. Garrett et al. CELL
- Immunity, Inflammation, and Cancer
- (2010) Sergei I. Grivennikov et al. CELL
- MyD88-mediated signaling prevents development of adenocarcinomas of the colon: role of interleukin 18
- (2010) Rosalba Salcedo et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Generation of pathogenic TH17 cells in the absence of TGF-β signalling
- (2010) Kamran Ghoreschi et al. NATURE
- Escherichia coli induces DNA damage in vivo and triggers genomic instability in mammalian cells
- (2010) G. Cuevas-Ramos et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses
- (2009) Shaoguang Wu et al. NATURE MEDICINE
- Modulation of the Intestinal Microbiota Alters Colitis-Associated Colorectal Cancer Susceptibility
- (2009) Joshua M. Uronis et al. PLoS One
- The Innate Immune Receptor Nod1 Protects the Intestine from Inflammation-Induced Tumorigenesis
- (2008) G. Y. Chen et al. CANCER RESEARCH
- Enterococcus faecalis Induces Aneuploidy and Tetraploidy in Colonic Epithelial Cells through a Bystander Effect
- (2008) X. Wang et al. CANCER RESEARCH
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started