Small-molecule inhibitors prevent the genotoxic and protumoural effects induced by colibactin-producing bacteria

Bacterial genotoxin colibactin promotes colon tumour growth by inducing a senescence-associated secretory phenotype

(2014) Antony Cougnoux et al.   GUT

Colonic mucosa-associated diffusely adherentafaC+ Escherichia coliexpressinglpfAandpksare increased in inflammatory bowel disease and colon cancer

(2013) Maelle Prorok-Hamon et al.   GUT

High Prevalence of Mucosa-Associated E. coli Producing Cyclomodulin and Genotoxin in Colon Cancer

(2013) Emmanuel Buc et al.   PLoS One

Analysis of Structure–Function Relationships in the Colibactin-Maturating Enzyme ClbP

(2012) Antony Cougnoux et al.   JOURNAL OF MOLECULAR BIOLOGY

A bacterial driver–passenger model for colorectal cancer: beyond the usual suspects

(2012) Harold Tjalsma et al.   NATURE REVIEWS MICROBIOLOGY

Intestinal Inflammation Targets Cancer-Inducing Activity of the Microbiota

(2012) J. C. Arthur et al.   SCIENCE

Cancer statistics, 2011

(2011) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

ClbP Is a Prototype of a Peptidase Subgroup Involved in Biosynthesis of Nonribosomal Peptides

(2011) Damien Dubois et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A natural prodrug activation mechanism in nonribosomal peptide synthesis

(2011) Daniela Reimer et al.   Nature Chemical Biology

PaDEL-descriptor: An open source software to calculate molecular descriptors and fingerprints

(2010) Chun Wei Yap   JOURNAL OF COMPUTATIONAL CHEMISTRY

Design, Synthesis, Crystal Structures, and Antimicrobial Activity of Sulfonamide Boronic Acids as β-Lactamase Inhibitors

(2010) Oliv Eidam et al.   JOURNAL OF MEDICINAL CHEMISTRY

Escherichia coli induces DNA damage in vivo and triggers genomic instability in mammalian cells

(2010) G. Cuevas-Ramos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Boronic acids in medicinal chemistry: anticancer, antibacterial and antiviral applications

(2010) Paul C. Trippier et al.   MedChemComm

Therapeutic potential of boron-containing compounds

(2009) Stephen J Baker et al.   Future Medicinal Chemistry

Genetic Structure and Distribution of the Colibactin Genomic Island among Members of the Family Enterobacteriaceae

(2009) J. Putze et al.   INFECTION AND IMMUNITY

Modulation of the Intestinal Microbiota Alters Colitis-Associated Colorectal Cancer Susceptibility

(2009) Joshua M. Uronis et al.   PLoS One

Drug Discovery and Natural Products: End of an Era or an Endless Frontier?

(2009) J. W.-H. Li et al.   SCIENCE

Lone pair–π interactions: a new supramolecular bond?

(2008) Tiddo J. Mooibroek et al.   CRYSTENGCOMM

Genomic and Epigenetic Instability in Colorectal Cancer Pathogenesis

(2008) William M. Grady et al.   GASTROENTEROLOGY

Molecular Epidemiology and Phylogenetic Distribution of the Escherichia coli pks Genomic Island

(2008) J. R. Johnson et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Total biosynthesis: in vitro reconstitution of polyketide and nonribosomal peptide pathways

(2008) Elizabeth S. Sattely et al.   NATURAL PRODUCT REPORTS

Cl-π interactions in protein-ligand complexes

(2008) Yumi N. Imai et al.   PROTEIN SCIENCE