Nutritional Modulation of the Microbiome and Immune Response

B cell-intrinsic epigenetic modulation of antibody responses by dietary fiber-derived short-chain fatty acids

(2020) Helia N. Sanchez et al.   Nature Communications

Short-term consumption of a high-fat diet increases host susceptibility to Listeria monocytogenes infection

(2019) Vanessa Las Heras et al.   Microbiome

High-fat diet disturbs lipid raft/TGF-β signaling-mediated maintenance of hematopoietic stem cells in mouse bone marrow

(2019) François Hermetet et al.   Nature Communications

Interleukin-22 protects intestinal stem cells against genotoxic stress

(2019) Konrad Gronke et al.   NATURE

The Microbiome and Food Allergy

(2019) Onyinye I. Iweala et al.   Annual Review of Immunology

Microbiota-Derived Short-Chain Fatty Acids Promote the Memory Potential of Antigen-Activated CD8+ T Cells

(2019) Annabell Bachem et al.   IMMUNITY

The Bone Marrow Protects and Optimizes Immunological Memory during Dietary Restriction

(2019) Nicholas Collins et al.   CELL

Dietary Intake Regulates the Circulating Inflammatory Monocyte Pool

(2019) Stefan Jordan et al.   CELL

High Glucose Intake Exacerbates Autoimmunity through Reactive-Oxygen-Species-Mediated TGF-β Cytokine Activation

(2019) Dunfang Zhang et al.   IMMUNITY

Recovery of the Gut Microbiota after Antibiotics Depends on Host Diet, Community Context, and Environmental Reservoirs

(2019) Katharine Michelle Ng et al.   Cell Host & Microbe

Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4+ T Cell Pathogenicity and Suppresses Autoimmunity

(2019) Stefano Angiari et al.   Cell Metabolism

Dietary Fiber Confers Protection against Flu by Shaping Ly6c − Patrolling Monocyte Hematopoiesis and CD8 + T Cell Metabolism

(2018) Aurélien Trompette et al.   IMMUNITY

Innate Nutritional Immunity

(2018) Gabriel Núñez et al.   JOURNAL OF IMMUNOLOGY

Gut bacteria selectively promoted by dietary fibers alleviate type 2 diabetes

(2018) Liping Zhao et al.   SCIENCE

Dimethyl fumarate targets GAPDH and aerobic glycolysis to modulate immunity

(2018) Michael D. Kornberg et al.   SCIENCE

Energy intake is associated with endotoxemia in apparently healthy men

(2018) Jacques Amar et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Commensals Suppress Intestinal Epithelial Cell Retinoic Acid Synthesis to Regulate Interleukin-22 Activity and Prevent Microbial Dysbiosis

(2018) Mayara Grizotte-Lake et al.   IMMUNITY

Glucose metabolism mediates disease tolerance in cerebral malaria

(2018) Andrew Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An update on immune dysregulation in obesity-related insulin resistance

(2018) Gholamreza Daryabor et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

The Human Microbiome and Child Growth – First 1000 Days and Beyond

(2018) Ruairi C. Robertson et al.   TRENDS IN MICROBIOLOGY

Dietary Salt Exacerbates Experimental Colitis

(2017) Alan L. Tubbs et al.   JOURNAL OF IMMUNOLOGY

Microbiota-activated PPAR-γ signaling inhibits dysbiotic Enterobacteriaceae expansion

(2017) Mariana X. Byndloss et al.   SCIENCE

Gut Microbiota as a Trigger of Accelerated Directional Adaptive Evolution: Acquisition of Herbivory in the Context of Extracellular Vesicles, MicroRNAs and Inter-Kingdom Crosstalk

(2017) Marco Romano   Frontiers in Microbiology

Short-term high-fat feeding induces islet macrophage infiltration and β-cell replication independently of insulin resistance in mice

(2016) David C. Woodland et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

A Dietary Fiber-Deprived Gut Microbiota Degrades the Colonic Mucus Barrier and Enhances Pathogen Susceptibility

(2016) Mahesh S. Desai et al.   CELL

Opposing Effects of Fasting Metabolism on Tissue Tolerance in Bacterial and Viral Inflammation

(2016) Andrew Wang et al.   CELL

Gut Microbial Metabolites Fuel Host Antibody Responses

(2016) Myunghoo Kim et al.   Cell Host & Microbe

Colonic Pro-inflammatory Macrophages Cause Insulin Resistance in an Intestinal Ccl2/Ccr2-Dependent Manner

(2016) Yoshinaga Kawano et al.   Cell Metabolism

Patients Perceive Clinical Benefit with the Specific Carbohydrate Diet for Inflammatory Bowel Disease

(2016) David L. Suskind et al.   DIGESTIVE DISEASES AND SCIENCES

Impact of iron deficiency anemia on the function of the immune system in children

(2016) Tamer Hasan Hassan et al.   MEDICINE

Microbiota metabolite short-chain fatty acid acetate promotes intestinal IgA response to microbiota which is mediated by GPR43

(2016) W Wu et al.   Mucosal Immunology

High-fat diet enhances stemness and tumorigenicity of intestinal progenitors

(2016) Semir Beyaz et al.   NATURE

Diet-induced extinctions in the gut microbiota compound over generations

(2016) Erica D. Sonnenburg et al.   NATURE

Foxp3 and Toll-like receptor signaling balance Treg cell anabolic metabolism for suppression

(2016) Valerie A Gerriets et al.   NATURE IMMUNOLOGY

Gut bacteria that prevent growth impairments transmitted by microbiota from malnourished children

(2016) L. V. Blanton et al.   SCIENCE

Linking the Microbiota, Chronic Disease, and the Immune System

(2016) Timothy W. Hand et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Dietary Fiber and Bacterial SCFA Enhance Oral Tolerance and Protect against Food Allergy through Diverse Cellular Pathways

(2016) Jian Tan et al.   Cell Reports

Oral iron supplements increase hepcidin and decrease iron absorption from daily or twice-daily doses in iron-depleted young women

(2015) D. Moretti et al.   BLOOD

Cultivating Healthy Growth and Nutrition through the Gut Microbiota

(2015) Sathish Subramanian et al.   CELL

Personalized Nutrition by Prediction of Glycemic Responses

(2015) David Zeevi et al.   CELL

Regulation of Obesity-Related Insulin Resistance with Gut Anti-inflammatory Agents

(2015) Helen Luck et al.   Cell Metabolism

Sugar, fat, and protein: new insights into what T cells crave

(2015) Greg M Delgoffe et al.   CURRENT OPINION IN IMMUNOLOGY

Environmental Enteric Dysfunction: An Overview

(2015) Rosie J. Crane et al.   FOOD AND NUTRITION BULLETIN

Dietary Fatty Acids Directly Impact Central Nervous System Autoimmunity via the Small Intestine

(2015) Aiden Haghikia et al.   IMMUNITY

A High–Glycemic Index, Low-Fiber Breakfast Affects the Postprandial Plasma Glucose, Insulin, and Ghrelin Responses of Patients with Type 2 Diabetes in a Randomized Clinical Trial

(2015) Flávia M Silva et al.   JOURNAL OF NUTRITION

Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration

(2015) Caroline A. Lindemans et al.   NATURE

Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome

(2015) Benoit Chassaing et al.   NATURE

Glucose Metabolism Regulates T Cell Activation, Differentiation, and Functions

(2015) Clovis S. Palmer et al.   Frontiers in Immunology

Environmental Enteropathy, Oral Vaccine Failure and Growth Faltering in Infants in Bangladesh

(2015) Caitlin Naylor et al.   EBioMedicine

Akkermansia muciniphila inversely correlates with the onset of inflammation, altered adipose tissue metabolism and metabolic disorders during obesity in mice

(2015) Marc Schneeberger et al.   Scientific Reports

Can We Say What Diet Is Best for Health?

(2014) D.L. Katz et al.   Annual Review of Public Health

Environmental enteropathy and malnutrition: do we know enough to intervene?

(2014) William A Petri et al.   BMC Medicine

Role of the Microbiota in Immunity and Inflammation

(2014) Yasmine Belkaid et al.   CELL

Starving our Microbial Self: The Deleterious Consequences of a Diet Deficient in Microbiota-Accessible Carbohydrates

(2014) Erica D. Sonnenburg et al.   Cell Metabolism

Environmental Enteric Dysfunction: Pathogenesis, Diagnosis, and Clinical Consequences

(2014) Gerald T. Keusch et al.   CLINICAL INFECTIOUS DISEASES

Crosstalk between intestinal microbiota, adipose tissue and skeletal muscle as an early event in systemic low-grade inflammation and the development of obesity and diabetes

(2014) Christian Bleau et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Prevalence of Childhood and Adult Obesity in the United States, 2011-2012

(2014) Cynthia L. Ogden et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Metabolic Reprogramming of Macrophages

(2014) Alex J. Freemerman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation

(2014) Valerie A. Gerriets et al.   JOURNAL OF CLINICAL INVESTIGATION

Metabolic Reprogramming Is Required for Antibody Production That Is Suppressed in Anergic but Exaggerated in Chronically BAFF-Exposed B Cells

(2014) A. Caro-Maldonado et al.   JOURNAL OF IMMUNOLOGY

Persistent gut microbiota immaturity in malnourished Bangladeshi children

(2014) Sathish Subramanian et al.   NATURE

The AGC kinase SGK1 regulates TH1 and TH2 differentiation downstream of the mTORC2 complex

(2014) Emily B Heikamp et al.   NATURE IMMUNOLOGY

The effect of the macrobiotic Ma-Pi 2 diet vs. the recommended diet in the management of type 2 diabetes: the randomized controlled MADIAB trial

(2014) Andreea Soare et al.   Nutrition & Metabolism

Patterned progression of bacterial populations in the premature infant gut

(2014) P. S. La Rosa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adaptation of Innate Lymphoid Cells to a Micronutrient Deficiency Promotes Type 2 Barrier Immunity

(2014) S. P. Spencer et al.   SCIENCE

Exploring host-microbiota interactions in animal models and humans

(2013) A. D. Kostic et al.   GENES & DEVELOPMENT

Vitamin A and dendritic cell differentiation

(2013) Marieke R. Beijer et al.   IMMUNOLOGY

Retinoic acid controls the homeostasis of pre-cDC–derived splenic and intestinal dendritic cells

(2013) Christopher A. Klebanoff et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Inflammasome-Mediated Secretion of IL-1  in Human Monocytes through TLR2 Activation; Modulation by Dietary Fatty Acids

(2013) R. G. Snodgrass et al.   JOURNAL OF IMMUNOLOGY

Richness of human gut microbiome correlates with metabolic markers

(2013) Emmanuelle Le Chatelier et al.   NATURE

Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

(2013) Yukihiro Furusawa et al.   NATURE

Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation

(2013) Nicholas Arpaia et al.   NATURE

Induction of pathogenic TH17 cells by inducible salt-sensing kinase SGK1

(2013) Chuan Wu et al.   NATURE

Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells

(2013) Markus Kleinewietfeld et al.   NATURE

Ultra-processed products are becoming dominant in the global food system

(2013) C. A. Monteiro et al.   Obesity Reviews

Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity

(2013) A. Everard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic Treg Cell Homeostasis

(2013) P. M. Smith et al.   SCIENCE

ZIP8 Regulates Host Defense through Zinc-Mediated Inhibition of NF-κB

(2013) Ming-Jie Liu et al.   Cell Reports

Double burden of malnutrition: A silent driver of double burden of disease in low– and middle–income countries

(2013) Ivana Kolčić   Journal of Global Health

Transient Inability to Manage Proteobacteria Promotes Chronic Gut Inflammation in TLR5-Deficient Mice

(2012) Frederic A. Carvalho et al.   Cell Host & Microbe

Comparison of Immune Responses to the O-Specific Polysaccharide and Lipopolysaccharide of Vibrio cholerae O1 in Bangladeshi Adult Patients with Cholera

(2012) Russell A. Johnson et al.   Clinical and Vaccine Immunology

Interleukin-22 Protects Intestinal Stem Cells from Immune-Mediated Tissue Damage and Regulates Sensitivity to Graft versus Host Disease

(2012) Alan M. Hanash et al.   IMMUNITY

Structural resilience of the gut microbiota in adult mice under high-fat dietary perturbations

(2012) Chenhong Zhang et al.   ISME Journal

Short Term High Fat Diet Challenge Promotes Alternative Macrophage Polarization in Adipose Tissue via Natural Killer T Cells and Interleukin-4

(2012) Yewei Ji et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein Energy Malnutrition Decreases Immunity and Increases Susceptibility to Influenza Infection in Mice

(2012) Andrew K. Taylor et al.   JOURNAL OF INFECTIOUS DISEASES

Immunological complications of obesity

(2012) Thirumala-Devi Kanneganti et al.   NATURE IMMUNOLOGY

The impoverished gut—a triple burden of diarrhoea, stunting and chronic disease

(2012) Richard L. Guerrant et al.   Nature Reviews Gastroenterology & Hepatology

The role of the gut microbiota in nutrition and health

(2012) Harry J. Flint et al.   Nature Reviews Gastroenterology & Hepatology

Nutritional immunity: transition metals at the pathogen–host interface

(2012) M. Indriati Hood et al.   NATURE REVIEWS MICROBIOLOGY

Estimating the Global Prevalence of Zinc Deficiency: Results Based on Zinc Availability in National Food Supplies and the Prevalence of Stunting

(2012) K. Ryan Wessells et al.   PLoS One

High Fat Diet-Induced Gut Microbiota Exacerbates Inflammation and Obesity in Mice via the TLR4 Signaling Pathway

(2012) Kyung-Ah Kim et al.   PLoS One

Regulated Virulence Controls the Ability of a Pathogen to Compete with the Gut Microbiota

(2012) N. Kamada et al.   SCIENCE

Immuno-microbiota cross and talk: The new paradigm of metabolic diseases

(2012) Rémy Burcelin et al.   SEMINARS IN IMMUNOLOGY

Environmental enteropathy: critical implications of a poorly understood condition

(2012) Poonum S. Korpe et al.   TRENDS IN MOLECULAR MEDICINE

Exogenous Stimuli Maintain Intraepithelial Lymphocytes via Aryl Hydrocarbon Receptor Activation

(2011) Ying Li et al.   CELL

Intestinal mucosal adherence and translocation of commensal bacteria at the early onset of type 2 diabetes: molecular mechanisms and probiotic treatment

(2011) Jacques Amar et al.   EMBO Molecular Medicine

Essential Role for Retinoic Acid in the Promotion of CD4+ T Cell Effector Responses via Retinoic Acid Receptor Alpha

(2011) Jason A. Hall et al.   IMMUNITY

The Role of Retinoic Acid in Tolerance and Immunity

(2011) Jason A. Hall et al.   IMMUNITY

The Aryl Hydrocarbon Receptor Regulates Gut Immunity through Modulation of Innate Lymphoid Cells

(2011) Ju Qiu et al.   IMMUNITY

Fatty acid–induced NLRP3-ASC inflammasome activation interferes with insulin signaling

(2011) Haitao Wen et al.   NATURE IMMUNOLOGY

External influences on the immune system via activation of the aryl hydrocarbon receptor

(2011) Brigitta Stockinger et al.   SEMINARS IN IMMUNOLOGY

Propensity to high-fat diet-induced obesity in rats is associated with changes in the gut microbiota and gut inflammation

(2010) Claire Barbier de La Serre et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Novel therapeutic concepts * The epidemic of cardiovascular disease in the developing world: global implications

(2010) B. J. Gersh et al.   EUROPEAN HEART JOURNAL

The Sensing of Environmental Stimuli by Follicular Dendritic Cells Promotes Immunoglobulin A Generation in the Gut

(2010) Keiichiro Suzuki et al.   IMMUNITY

The role of iron in the immune response to bacterial infection

(2010) Bobby J. Cherayil   IMMUNOLOGIC RESEARCH

High-Fat Diet: Bacteria Interactions Promote Intestinal Inflammation Which Precedes and Correlates with Obesity and Insulin Resistance in Mouse

(2010) Shengli Ding et al.   PLoS One

Succession of microbial consortia in the developing infant gut microbiome

(2010) J. E. Koenig et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nutritional imbalances and infections affect the thymus: consequences on T-cell-mediated immune responses

(2010) Wilson Savino et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

Protein-energy malnutrition halts hemopoietic progenitor cells in the G0/G1 cell cycle stage, thereby altering cell production rates

(2009) P. Borelli et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Salt and high blood pressure

(2009) Sailesh Mohan et al.   CLINICAL SCIENCE

High-Fat Diet Determines the Composition of the Murine Gut Microbiome Independently of Obesity

(2009) Marie A. Hildebrandt et al.   GASTROENTEROLOGY

Retinoic Acid Can Directly Promote TGF-β-Mediated Foxp3+ Treg Cell Conversion of Naive T Cells

(2009) Daniel Mucida et al.   IMMUNITY

Mucosal Immunity after Vaccination with Monovalent and Trivalent Oral Poliovirus Vaccine in India

(2009) Nicholas C. Grassly et al.   JOURNAL OF INFECTIOUS DISEASES

Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43

(2009) Kendle M. Maslowski et al.   NATURE

Chemokine CXCL13 is essential for lymph node initiation and is induced by retinoic acid and neuronal stimulation

(2009) Serge A van de Pavert et al.   NATURE IMMUNOLOGY

Normalization of obesity-associated insulin resistance through immunotherapy

(2009) Shawn Winer et al.   NATURE MEDICINE

Diet-Induced Obesity Is Linked to Marked but Reversible Alterations in the Mouse Distal Gut Microbiome

(2008) Peter J. Turnbaugh et al.   Cell Host & Microbe

Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced Inflammation in High-Fat Diet-Induced Obesity and Diabetes in Mice

(2008) P. D. Cani et al.   DIABETES

Antibiotics protect against fructose-induced hepatic lipid accumulation in mice: Role of endotoxin

(2008) Ina Bergheim et al.   JOURNAL OF HEPATOLOGY