Distinct peripheral blood monocyte and neutrophil transcriptional programs following intracerebral hemorrhage and different etiologies of ischemic stroke

Activation of GPR43 suppresses TNF-α-induced inflammatory response in human fibroblast-like synoviocytes

(2020) Chi Zhang et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Neuroinflammation after Intracerebral Hemorrhage and Potential Therapeutic Targets

(2020) Christine Tschoe et al.   Journal of Stroke

Bioinformatics analysis of vascular RNA-seq data revealed hub genes and pathways in a novel Tibetan minipig atherosclerosis model induced by a high fat/cholesterol diet

(2020) Yongming Pan et al.   Lipids in Health and Disease

RNA-sequencing analysis of differential gene expression associated with arterial stiffness

(2020) Jeongok G Logan et al.   Vascular

Functional Dynamics of Neutrophils After Ischemic Stroke

(2019) Wei Cai et al.   Translational Stroke Research

MicroRNA and their target mRNAs change expression in whole blood of patients after intracerebral hemorrhage

(2019) Xiyuan Cheng et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The Involvement and Therapy Target of Immune Cells After Ischemic Stroke

(2019) Zhihong Jian et al.   Frontiers in Immunology

Hypoxia-induced lncRNA EIF3J-AS1 accelerates hepatocellular carcinoma progression via targeting miR-122–5p/CTNND2 axis

(2019) Xue Yang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Immune responses in stroke: how the immune system contributes to damage and healing after stroke and how this knowledge could be translated to better cures?

(2018) Aditya Rayasam et al.   IMMUNOLOGY

Role of Human Macrophage Polarization in Inflammation during Infectious Diseases

(2018) Chiraz Atri et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The intracerebral hemorrhage blood transcriptome in humans differs from the ischemic stroke and vascular risk factor control blood transcriptomes

(2018) Boryana Stamova et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Implications of polymorphonuclear neutrophils for ischemic stroke and intracerebral hemorrhage: Predictive value, pathophysiological consequences and utility as therapeutic target

(2018) Dirk M. Hermann et al.   JOURNAL OF NEUROIMMUNOLOGY

Platelet-derived growth factor-C and -D in the cardiovascular system and diseases

(2018) Chunsik Lee et al.   MOLECULAR ASPECTS OF MEDICINE

Beneficial Role of Neutrophils Through Function of Lactoferrin After Intracerebral Hemorrhage

(2018) Xiurong Zhao et al.   STROKE

The synaptic receptor Lrp4 promotes peripheral nerve regeneration

(2018) Katherine D. Gribble et al.   Nature Communications

Extracellular Neutrophil Proteases Are Efficient Regulators of IL-1, IL-33, and IL-36 Cytokine Activity but Poor Effectors of Microbial Killing

(2018) Danielle M. Clancy et al.   Cell Reports

Myeloid cells as therapeutic targets in neuroinflammation after stroke: Specific roles of neutrophils and neutrophil–platelet interactions

(2018) Alicia García-Culebras et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Expression of combinatorial immunoglobulins in macrophages in the tumor microenvironment

(2018) Tina Fuchs et al.   PLoS One

Roles of integrins and extracellular matrix in stroke

(2018) Danielle Edwards et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Rapamycin in ischemic stroke: Old drug, new tricks?

(2018) Gina Hadley et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Expression profiles of long noncoding RNAs and mRNAs in peripheral blood mononuclear cells of patients with acute myocardial infarction

(2018) Pingsen Zhao et al.   MEDICINE

Microglia and Monocytes/Macrophages Polarization Reveal Novel Therapeutic Mechanism against Stroke

(2017) Masato Kanazawa et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Activation of peroxisome proliferator-activated receptor–γ by a 12/15-lipoxygenase product of arachidonic acid: a possible neuroprotective effect in the brain after experimental intracerebral hemorrhage

(2017) Ruobing Xu et al.   JOURNAL OF NEUROSURGERY

Lymphocyte-to-Monocyte Ratio: A Novel Predictor of the Prognosis of Acute Ischemic Stroke

(2017) Hao Ren et al.   Journal of Stroke & Cerebrovascular Diseases

Neutrophil-to-Lymphocyte Ratio Is a Prognostic Marker in Acute Ischemic Stroke

(2017) Jie Xue et al.   Journal of Stroke & Cerebrovascular Diseases

PUM1 is a biphasic negative regulator of innate immunity genes by suppressing LGP2

(2017) Yonghong Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Astrocytic Lrp4 (Low-Density Lipoprotein Receptor–Related Protein 4) Contributes to Ischemia-Induced Brain Injury by Regulating ATP Release and Adenosine-A2AR (Adenosine A2A Receptor) Signaling

(2017) Xin-Chun Ye et al.   STROKE

IL-23 (Interleukin-23)–Producing Conventional Dendritic Cells Control the Detrimental IL-17 (Interleukin-17) Response in Stroke

(2017) Mathias Gelderblom et al.   STROKE

RNA-seq expression profiling of rat MCAO model following reperfusion Orexin-A

(2017) Chun-Mei Wang et al.   Oncotarget

Lymphocyte-to-Monocyte Ratio: A Novel Predictor of the Prognosis of Acute Ischemic Stroke

(2017) Hao Ren et al.   Journal of Stroke & Cerebrovascular Diseases

Neutrophil-to-Lymphocyte Ratio Is a Prognostic Marker in Acute Ischemic Stroke

(2017) Jie Xue et al.   Journal of Stroke & Cerebrovascular Diseases

Hypercholesterolemia induced cerebral small vessel disease

(2017) Peter Kraft et al.   PLoS One

Benchmarking of RNA-sequencing analysis workflows using whole-transcriptome RT-qPCR expression data

(2017) Celine Everaert et al.   Scientific Reports

Dendritic cells in brain diseases

(2016) Peter Ludewig et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

GM-CSF: From Growth Factor to Central Mediator of Tissue Inflammation

(2016) Burkhard Becher et al.   IMMUNITY

Attenuation of Blood-Brain Barrier Breakdown and Hyperpermeability by Calpain Inhibition

(2016) Himakarnika Alluri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cell Surface CD36 Protein in Monocyte/Macrophage Contributes to Phagocytosis during the Resolution Phase of Ischemic Stroke in Mice

(2016) Moon-Sook Woo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Notch signaling in cerebrovascular diseases (Review)

(2016) Zhiyou Cai et al.   Molecular Medicine Reports

Heterogeneity of B Cell Functions in Stroke-Related Risk, Prevention, Injury, and Repair

(2016) Uma Maheswari Selvaraj et al.   Neurotherapeutics

Stages of the Inflammatory Response in Pathology and Tissue Repair after Intracerebral Hemorrhage

(2016) Michael Askenase et al.   SEMINARS IN NEUROLOGY

The Role of Monocytes in Ischemic Stroke Pathobiology: New Avenues to Explore

(2016) Ayman ElAli et al.   Frontiers in Aging Neuroscience

Intracerebral Hemorrhage: Perihemorrhagic Edema and Secondary Hematoma Expansion: From Bench Work to Ongoing Controversies

(2016) Manoj K. Mittal et al.   Frontiers in Neurology

Inflammation after Ischemic Stroke: The Role of Leukocytes and Glial Cells

(2016) Jong Youl Kim et al.   Experimental Neurobiology

Human and mouse monocytes display distinct signalling and cytokine profiles upon stimulation with FFAR2/FFAR3 short-chain fatty acid receptor agonists

(2016) Zhiwei Ang et al.   Scientific Reports

Comparing the normalization methods for the differential analysis of Illumina high-throughput RNA-Seq data

(2015) Peipei Li et al.   BMC BIOINFORMATICS

Targeting Neutrophils in Ischemic Stroke: Translational Insights from Experimental Studies

(2015) Glen C Jickling et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

MiR-200b modulates the properties of human monocyte-derived dendritic cells by targeting WASF3

(2015) Yuanlin Liu et al.   LIFE SCIENCES

The landscape of long noncoding RNAs in the human transcriptome

(2015) Matthew K Iyer et al.   NATURE GENETICS

Loss of FFA2 and FFA3 increases insulin secretion and improves glucose tolerance in type 2 diabetes

(2015) Cong Tang et al.   NATURE MEDICINE

The Role of Different Monocyte Subsets in the Pathogenesis of Atherosclerosis and Acute Coronary Syndromes

(2015) E. Idzkowska et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

(2015) et al.   SCIENCE

Tissue-based map of the human proteome

(2015) M. Uhlen et al.   SCIENCE

Interleukin-1 and acute brain injury

(2015) Katie N. Murray et al.   Frontiers in Cellular Neuroscience

Intracerebral Hemorrhage and Ischemic Stroke of Different Etiologies Have Distinct Alternatively Spliced mRNA Profiles in the Blood: a Pilot RNA-seq Study

(2015) Cheryl Dykstra-Aiello et al.   Translational Stroke Research

The CNS glucagon-like peptide-2 receptor in the control of energy balance and glucose homeostasis

(2014) Xinfu Guan   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Cutting through the Complexities of mTOR for the Treatment of Stroke

(2014) Kenneth Maiese   CURRENT NEUROVASCULAR RESEARCH

miR-150 promotes the proliferation and migration of lung cancer cells by targeting SRC kinase signalling inhibitor 1

(2014) Minghui Cao et al.   EUROPEAN JOURNAL OF CANCER

Upregulated expression of human alpha-defensins 1, 2 and 3 in hypercholesteremia and its relationship with serum lipid levels

(2014) Yun-Xi Li et al.   HUMAN IMMUNOLOGY

Pro-Inflammatory Interferon Gamma Signaling is Directly Associated with Stroke Induced Neurodegeneration

(2014) Hilary A. Seifert et al.   Journal of Neuroimmune Pharmacology

A Critical Role for Interferon Regulatory Factor 9 in Cerebral Ischemic Stroke

(2014) H.-Z. Chen et al.   JOURNAL OF NEUROSCIENCE

CCR2+Ly6Chi Inflammatory Monocyte Recruitment Exacerbates Acute Disability Following Intracerebral Hemorrhage

(2014) M. D. Hammond et al.   JOURNAL OF NEUROSCIENCE

Inhibition of Src Family Kinases Protects Hippocampal Neurons and Improves Cognitive Function after Traumatic Brain Injury

(2014) Da Zhi Liu et al.   JOURNAL OF NEUROTRAUMA

Sequencing depth and coverage: key considerations in genomic analyses

(2014) David Sims et al.   NATURE REVIEWS GENETICS

microRNA Expression in Peripheral Blood Cells following Acute Ischemic Stroke and Their Predicted Gene Targets

(2014) Glen C. Jickling et al.   PLoS One

Neuroinflammation after intracerebral hemorrhage

(2014) Eva Mracsko et al.   Frontiers in Cellular Neuroscience

Molecular and Cellular Immune Responses to Ischemic Brain Injury

(2014) Hilary A. Seifert et al.   Translational Stroke Research

From Monocytes to M1/M2 Macrophages: Phenotypical vs. Functional Differentiation

(2014) Paola Italiani et al.   Frontiers in Immunology

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

Causal analysis approaches in Ingenuity Pathway Analysis

(2013) Andreas Krämer et al.   BIOINFORMATICS

Clinical significance of plasma VEGF value in ischemic stroke - research for biomarkers in ischemic stroke (REBIOS) study

(2013) Ryu Matsuo et al.   BMC Neurology

Transcriptional Regulation and Its Misregulation in Disease

(2013) Tong Ihn Lee et al.   CELL

Activation of the Ig Iα1 promoter by the transcription factor Ets-1 triggers Ig Iα1–Cα1 germline transcription in epithelial cancer cells

(2013) Zhi Duan et al.   Cellular & Molecular Immunology

Vascular endothelial growth factors (VEGFs) and stroke

(2013) David A. Greenberg et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Weighted Gene Coexpression Network Analysis of Human Left Atrial Tissue Identifies Gene Modules Associated With Atrial Fibrillation

(2013) Nicholas Tan et al.   Circulation-Cardiovascular Genetics

Peroxisome Proliferator-activated Receptor γ Coactivator 1 (PGC-1)- and Estrogen-related Receptor (ERR)-induced Regulator in Muscle 1 (PERM1) Is a Tissue-specific Regulator of Oxidative Capacity in Skeletal Muscle Cells

(2013) Yoshitake Cho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Genotype-Tissue Expression (GTEx) project

(2013) John Lonsdale et al.   NATURE GENETICS

N2 Neutrophils, Novel Players in Brain Inflammation After Stroke

(2013) María Isabel Cuartero et al.   STROKE

Role of Inflammation and Its Mediators in Acute Ischemic Stroke

(2013) Rong Jin et al.   Journal of Cardiovascular Translational Research

Different prognostic value of white blood cell subtypes in patients with acute cerebral infarction

(2012) Jinkwon Kim et al.   ATHEROSCLEROSIS

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Different Temporal Patterns in the Expressions of Bone Morphogenetic Proteins and Noggin During Astroglial Scar Formation After Ischemic Stroke

(2012) Jin A. Shin et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Endothelial Cell–Specific FGD5 Involvement in Vascular Pruning Defines Neovessel Fate in Mice

(2012) Caroline Cheng et al.   CIRCULATION

Gonadotropin-Releasing Hormone Receptor System: Modulatory Role in Aging and Neurodegeneration

(2012) Liyun Wang et al.   CNS & Neurological Disorders-Drug Targets

E2F7 and E2F8 promote angiogenesis through transcriptional activation of VEGFA in cooperation with HIF1

(2012) Bart G M W Weijts et al.   EMBO JOURNAL

The CCL2-CCR2 system affects the progression and clearance of intracerebral hemorrhage

(2012) Yao Yao et al.   GLIA

The Neuroprotective Functions of Transforming Growth Factor Beta Proteins

(2012) Arpád Dobolyi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Human neutrophil alpha-defensins induce formation of fibrinogen and thrombospondin-1 amyloid-like structures and activate platelets via glycoprotein IIb/IIIa

(2012) M. HORN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Gr1+ Macrophages and Dendritic Cells Dominate the Inflammatory Infiltrate 12 h After Experimental Intracerebral Hemorrhage

(2012) Matthew D. Hammond et al.   Translational Stroke Research

Post-Ischemic Inflammation in the Brain

(2012) Takashi Shichita et al.   Frontiers in Immunology

Profiles of lacunar and nonlacunar stroke

(2011) Glen C. Jickling et al.   ANNALS OF NEUROLOGY

Anti-Adrenergic Medications and Edema Development after Intracerebral Hemorrhage

(2011) L. H. Sansing et al.   Neurocritical Care

Gene Expression Profiling of Blood in Brain Arteriovenous Malformation Patients

(2011) Shantel M. Weinsheimer et al.   Translational Stroke Research

Inflammatory mechanisms in ischemic stroke: role of inflammatory cells

(2010) Rong Jin et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Immunoglobulin Expression in Non-Lymphoid Lineage and Neoplastic Cells

(2009) Zhengshan Chen et al.   AMERICAN JOURNAL OF PATHOLOGY

A HaemAtlas: characterizing gene expression in differentiated human blood cells

(2009) Nicholas A. Watkins et al.   BLOOD

Brain dendritic cells in ischemic stroke: Time course, activation state, and origin

(2009) Jennifer C. Felger et al.   BRAIN BEHAVIOR AND IMMUNITY

Transient decrease in circulating dendritic cell precursors after acute stroke: potential recruitment into the brain

(2009) Atilla Yilmaz et al.   CLINICAL SCIENCE

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Dynamic changes of cell cycle elements in the ischemic brain after bone marrow stromal cells transplantation in rats

(2009) Kefu Cai et al.   NEUROSCIENCE LETTERS

Gene Expression in Peripheral Blood Differs after Cardioembolic Compared with Large-Vessel Atherosclerotic Stroke: Biomarkers for the Etiology of Ischemic Stroke

(2008) Huichun Xu et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH

Regulation of B-cell-activating factor (BAFF)/B lymphocyte stimulator (BLyS) expression in human neutrophils

(2007) Patrizia Scapini et al.   IMMUNOLOGY LETTERS