Genome editing of CXCR4 by CRISPR/cas9 confers cells resistant to HIV-1 infection
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Genome editing of CXCR4 by CRISPR/cas9 confers cells resistant to HIV-1 infection
Authors
Keywords
-
Journal
Scientific Reports
Volume 5, Issue 1, Pages -
Publisher
Springer Nature
Online
2015-10-20
DOI
10.1038/srep15577
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Inhibition of HIV-1 infection of primary CD4+ T-cells by gene editing of CCR5 using adenovirus-delivered CRISPR/Cas9
- (2015) Chang Li et al. JOURNAL OF GENERAL VIROLOGY
- CRISPR-Cas9: a new and promising player in gene therapy
- (2015) Lu Xiao-Jie et al. JOURNAL OF MEDICAL GENETICS
- Development and Applications of CRISPR-Cas9 for Genome Engineering
- (2014) Patrick D. Hsu et al. CELL
- Generation of Gene-Modified Cynomolgus Monkey via Cas9/RNA-Mediated Gene Targeting in One-Cell Embryos
- (2014) Yuyu Niu et al. CELL
- Efficient Ablation of Genes in Human Hematopoietic Stem and Effector Cells using CRISPR/Cas9
- (2014) Pankaj K. Mandal et al. Cell Stem Cell
- A Novel Approach to Block HIV-1 Coreceptor CXCR4 in Non-toxic Manner
- (2014) Ye Liu et al. MOLECULAR BIOTECHNOLOGY
- Improving CRISPR-Cas nuclease specificity using truncated guide RNAs
- (2014) Yanfang Fu et al. NATURE BIOTECHNOLOGY
- Diagnosis and management of lymphomas and other cancers in HIV-infected patients
- (2014) Antonino Carbone et al. Nature Reviews Clinical Oncology
- Gene Editing of CCR5 in Autologous CD4 T Cells of Persons Infected with HIV
- (2014) Pablo Tebas et al. NEW ENGLAND JOURNAL OF MEDICINE
- CCR5 Gene Disruption via Lentiviral Vectors Expressing Cas9 and Single Guided RNA Renders Cells Resistant to HIV-1 Infection
- (2014) Weiming Wang et al. PLoS One
- Seamless modification of wild-type induced pluripotent stem cells to the natural CCR5Δ32 mutation confers resistance to HIV infection
- (2014) Lin Ye et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Simultaneous zinc-finger nuclease editing of the HIV coreceptors ccr5 and cxcr4 protects CD4+ T cells from HIV-1 infection
- (2013) C. A. Didigu et al. BLOOD
- Inhibition of HIV-1 Transcription and Replication by a Newly Identified Cyclin T1 Splice Variant
- (2013) Guozhen Gao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Pre-clinical Modeling of CCR5 Knockout in Human Hematopoietic Stem Cells by Zinc Finger Nucleases Using Humanized Mice
- (2013) U. Hofer et al. JOURNAL OF INFECTIOUS DISEASES
- RNA-guided editing of bacterial genomes using CRISPR-Cas systems
- (2013) Wenyan Jiang et al. NATURE BIOTECHNOLOGY
- CRISPR/Cas9 systems targeting β-globin and CCR5 genes have substantial off-target activity
- (2013) Thomas J. Cradick et al. NUCLEIC ACIDS RESEARCH
- Zinc-finger-nucleases mediate specific and efficient excision of HIV-1 proviral DNA from infected and latently infected human T cells
- (2013) Xiying Qu et al. NUCLEIC ACIDS RESEARCH
- Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells
- (2013) Ophir Shalem et al. SCIENCE
- Genetic Screens in Human Cells Using the CRISPR-Cas9 System
- (2013) Tim Wang et al. SCIENCE
- Multiplex Genome Engineering Using CRISPR/Cas Systems
- (2013) L. Cong et al. SCIENCE
- Zinc-finger Nuclease Editing of Human cxcr4 Promotes HIV-1 CD4+ T Cell Resistance and Enrichment
- (2012) Jinyun Yuan et al. MOLECULAR THERAPY
- Engineering HIV-Resistant Human CD4+ T Cells with CXCR4-Specific Zinc-Finger Nucleases
- (2011) Craig B. Wilen et al. PLoS Pathogens
- The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway
- (2010) Michael R. Lieber Annual Review of Biochemistry
- Evidence for the cure of HIV infection by CCR5 32/ 32 stem cell transplantation
- (2010) K. Allers et al. BLOOD
- CXCL12 / CXCR4 / CXCR7 chemokine axis and cancer progression
- (2010) Xueqing Sun et al. CANCER AND METASTASIS REVIEWS
- Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo
- (2010) Nathalia Holt et al. NATURE BIOTECHNOLOGY
- RNA-Based Gene Therapy for HIV with Lentiviral Vector-Modified CD34+ Cells in Patients Undergoing Transplantation for AIDS-Related Lymphoma
- (2010) D. L. DiGiusto et al. Science Translational Medicine
- CXC chemokine receptor 4 expressed in T cells plays an important role in the development of collagen-induced arthritis
- (2010) Soo-Hyun Chung et al. ARTHRITIS RESEARCH & THERAPY
- CCR5 Deficiency Is a Risk Factor for Early Clinical Manifestations of West Nile Virus Infection but not for Viral Transmission
- (2009) Jean K. Lim et al. JOURNAL OF INFECTIOUS DISEASES
- Long-Term Control of HIV byCCR5Delta32/Delta32 Stem-Cell Transplantation
- (2009) Gero Hütter et al. NEW ENGLAND JOURNAL OF MEDICINE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started