CRISPR/Cas9-mediated knockout of NSD1 suppresses the hepatocellular carcinoma development via the NSD1/H3/Wnt10b signaling pathway

Risk factors and prevention of hepatocellular carcinoma in the era of precision medicine

(2018) Naoto Fujiwara et al.   JOURNAL OF HEPATOLOGY

Disruption ofNSD1in Head and Neck Cancer Promotes Favorable Chemotherapeutic Responses Linked to Hypomethylation

(2018) Nam Bui et al.   MOLECULAR CANCER THERAPEUTICS

The H3K36me2 Methyltransferase Nsd1 Demarcates PRC2-Mediated H3K27me2 and H3K27me3 Domains in Embryonic Stem Cells

(2018) Gundula Streubel et al.   MOLECULAR CELL

LncFZD6 initiates Wnt/β-catenin and liver TIC self-renewal through BRG1-mediated FZD6 transcriptional activation

(2018) Zhenzhen Chen et al.   ONCOGENE

CRISPR/Cas9-mediated knockout of the PDEF gene inhibits migration and invasion of human gastric cancer AGS cells

(2018) Yi-Qiang Zhang et al.   BIOMEDICINE & PHARMACOTHERAPY

CRISPR/Cas9-mediated genome engineering of CXCR4 decreases the malignancy of hepatocellular carcinoma cells in vitro and in vivo

(2017) Xiaoli Wang et al.   ONCOLOGY REPORTS

Recent advances in hepatocellular carcinoma therapy

(2017) Rinku Dutta et al.   PHARMACOLOGY & THERAPEUTICS

NSD1- and NSD2-damaging mutations define a subset of laryngeal tumors with favorable prognosis

(2017) Suraj Peri et al.   Nature Communications

Eukaryotic elongation factor 2 is a prognostic marker and its kinase a potential therapeutic target in HCC

(2017) Leona L. Pott et al.   Oncotarget

CRISPR/Cas9-mediated p53 and Pten dual mutation accelerates hepatocarcinogenesis in adult hepatitis B virus transgenic mice

(2017) Yongzhen Liu et al.   Scientific Reports

Knockout of the Nogo-B Gene Attenuates Tumor Growth and Metastasis in Hepatocellular Carcinoma

(2017) Bo Zhu et al.   NEOPLASIA

NSD1 inactivation defines an immune cold, DNA hypomethylated subtype in squamous cell carcinoma

(2017) Kevin Brennan et al.   Scientific Reports

Cancer statistics in China, 2015

(2016) Wanqing Chen et al.   CA-A CANCER JOURNAL FOR CLINICIANS

CRISPR–Cas9-mediated gene knockout in primary human airway epithelial cells reveals a proinflammatory role for MUC18

(2015) H W Chu et al.   GENE THERAPY

The NSD family of protein methyltransferases in human cancer

(2015) Theodore Vougiouklakis et al.   Epigenomics

The NSD 1 and EZH 2 Overgrowth Genes, Similarities and Differences

(2013) KATRINA TATTON-BROWN et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

NSD1 Mitigates Caspase-1 Activation by Listeriolysin O in Macrophages

(2013) Olivia S. Sakhon et al.   PLoS One

The role of WNT10B in physiology and disease

(2011) P. Wend et al.   Acta Physiologica

Hepatitis C virus core protein activates Wnt/β-catenin signaling through multiple regulation of upstream molecules in the SMMC-7721 cell line

(2011) Jiao Liu et al.   ARCHIVES OF VIROLOGY

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(2011) Mu-Yan Cai et al.   MOLECULAR MEDICINE

Epigenetic mechanisms in hepatocellular carcinoma: How environmental factors influence the epigenome

(2011) Zdenko Herceg et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

The MMSET histone methyl transferase switches global histone methylation and alters gene expression in t(4;14) multiple myeloma cells

(2010) E. Martinez-Garcia et al.   BLOOD

Chemokine receptor CXCR7 regulates the invasion,angiogenesis and tumor growth of human hepatocellular carcinoma cells

(2010) Ke Zheng et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Role for the nuclear receptor-binding SET domain protein 1 (NSD1) methyltransferase in coordinating lysine 36 methylation at histone 3 with RNA polymerase II function

(2010) A. K. Lucio-Eterovic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histone H3K27 methyltransferase Ezh2 represses Wnt genes to facilitate adipogenesis

(2010) L. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hepatoblastoma in a Patient with Sotos Syndrome

(2009) Motohiro Kato et al.   JOURNAL OF PEDIATRICS

Epigenetic inactivation of the Sotos overgrowth syndrome gene histone methyltransferase NSD1 in human neuroblastoma and glioma

(2009) M. Berdasco et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA