Boosting the autophagy-lysosomal pathway by phytochemicals: A potential therapeutic strategy against Alzheimer's disease

A Review of the Anti-Inflammatory Effects of Rosmarinic Acid on Inflammatory Diseases

(2020) Chunxu Luo et al.   Frontiers in Pharmacology

Autophagy in Alzheimer's disease and promising modulatory effects of herbal medicine

(2019) Qiang Zeng et al.   EXPERIMENTAL GERONTOLOGY

Autophagy induction by trehalose: Molecular mechanisms and therapeutic impacts

(2018) Kiana Hosseinpour-Moghaddam et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Inhibition of acid sphingomyelinase disrupts LYNUS signaling and triggers autophagy

(2018) Matthew J. Justice et al.   JOURNAL OF LIPID RESEARCH

A Self-Microemulsifying Formulation of Oxyresveratrol Prevents Amyloid Beta Protein-Induced Neurodegeneration in Mice

(2018) Yaowaporn Sangsen et al.   PLANTA MEDICA

Interplay Between the Autophagy-Lysosomal Pathway and the Ubiquitin-Proteasome System: A Target for Therapeutic Development in Alzheimer’s Disease

(2018) Hianara A. Bustamante et al.   Frontiers in Cellular Neuroscience

TFEB-driven endocytosis coordinates MTORC1 signaling and autophagy

(2018) Israel C. Nnah et al.   Autophagy

MPB, a novel berberine derivative, enhances lysosomal and bactericidal properties via TGF-β–activated kinase 1-dependent activating the transcription factor EB

(2018) Xiaojia Liu et al.   FASEB JOURNAL

The Flavonoid Apigenin Protects Brain Neurovascular Coupling against Amyloid-β25-35-Induced Toxicity in Mice

(2018) Rui Liu et al.   JOURNAL OF ALZHEIMERS DISEASE

The amino acid metabolite homocysteine activates mTORC1 to inhibit autophagy and form abnormal proteins in human neurons and mice

(2017) Khoosheh Khayati et al.   FASEB JOURNAL

Amyloid precursor protein and endosomal–lysosomal dysfunction in Alzheimer’s disease: inseparable partners in a multifactorial disease

(2017) Ralph A. Nixon   FASEB JOURNAL

Quercetin Attenuates Manganese-Induced Neuroinflammation by Alleviating Oxidative Stress through Regulation of Apoptosis, iNOS/NF-κB and HO-1/Nrf2 Pathways

(2017) Entaz Bahar et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Therapeutic effects of curcumin in inflammatory and immune-mediated diseases: A nature-made jack-of-all-trades?

(2017) Elham Abdollahi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Endo-lysosomal and autophagic dysfunction: a driving factor in Alzheimer's disease?

(2017) Lauren S. Whyte et al.   JOURNAL OF NEUROCHEMISTRY

Glycogen Reduction in Myotubes of Late-Onset Pompe Disease Patients Using Antisense Technology

(2017) Elisa Goina et al.   MOLECULAR THERAPY

The chemical evolution of oligonucleotide therapies of clinical utility

(2017) Anastasia Khvorova et al.   NATURE BIOTECHNOLOGY

Nusinersen, an antisense oligonucleotide drug for spinal muscular atrophy

(2017) David R Corey   NATURE NEUROSCIENCE

Mechanistic comparison of current pharmacological treatments and novel phytochemicals to target amyloid peptides in Alzheimer’s and neurodegenerative diseases

(2017) Neelima Ayyalasomayajula et al.   NUTRITIONAL NEUROSCIENCE

Curcumin: A potentially powerful tool to reverse cisplatin-induced toxicity

(2017) Ramin Rezaee et al.   PHARMACOLOGICAL RESEARCH

TMEM175 deficiency impairs lysosomal and mitochondrial function and increases α-synuclein aggregation

(2017) Sarah Jinn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases

(2017) Michela Palmieri et al.   Nature Communications

TFEB-mediated increase in peripheral lysosomes regulates store-operated calcium entry

(2017) Luigi Sbano et al.   Scientific Reports

Inhibitory Potency of Choline Esterase Inhibitors on Acetylcholine Release and Choline Esterase Activity in Fresh Specimens of Human and Rat Neocortex

(2017) Rolf Jackisch et al.   JOURNAL OF ALZHEIMERS DISEASE

Neuroinflammation in Alzheimer's disease: Current evidence and future directions

(2016) Valeria Calsolaro et al.   Alzheimers & Dementia

Pharmacological Effects of Active Components of Chinese Herbal Medicine in the Treatment of Alzheimer's Disease: A Review

(2016) Zhi-Yong Wang et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Lysosome calcium in ROS regulation of autophagy

(2016) Xiaoli Zhang et al.   Autophagy

Rosmarinic acid prevents against memory deficits in ischemic mice

(2016) Analu Aragão Fonteles et al.   BEHAVIOURAL BRAIN RESEARCH

Effects of curcumin on serum cytokine concentrations in subjects with metabolic syndrome: A post-hoc analysis of a randomized controlled trial

(2016) Yunes Panahi et al.   BIOMEDICINE & PHARMACOTHERAPY

Difluorinated Curcumin: A Promising Curcumin Analogue with Improved Anti-Tumor Activity and Pharmacokinetic Profile

(2016) Amir Abbas Momtazi et al.   CURRENT PHARMACEUTICAL DESIGN

Pharmacological, toxicological and neuronal localization assessment of galantamine/chitosan complex nanoparticles in rats: future potential contribution in Alzheimer’s disease management

(2016) Amira S. Hanafy et al.   DRUG DELIVERY

Curcumin Lowers Serum Lipids and Uric Acid in Subjects With Nonalcoholic Fatty Liver Disease

(2016) Yunes Panahi et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Mechanisms and functions of lysosome positioning

(2016) Jing Pu et al.   JOURNAL OF CELL SCIENCE

Melissa officinalis L. – A review of its traditional uses, phytochemistry and pharmacology

(2016) Abolfazl Shakeri et al.   JOURNAL OF ETHNOPHARMACOLOGY

Autophagic activation: A key piece of the puzzle for the curcumin-associated cognitive enhancement?

(2016) Amirhossein Sahebkar   JOURNAL OF PSYCHOPHARMACOLOGY

Role of microRNAs in the Therapeutic Effects of Curcumin in Non-Cancer Diseases

(2016) Amir Abbas Momtazi et al.   Molecular Diagnosis & Therapy

α-Synuclein–induced lysosomal dysfunction occurs through disruptions in protein trafficking in human midbrain synucleinopathy models

(2016) Joseph R. Mazzulli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MCOLN1 is a ROS sensor in lysosomes that regulates autophagy

(2016) Xiaoli Zhang et al.   Nature Communications

Unfolded p53 in the pathogenesis of Alzheimer's disease: is HIPK2 the link?

(2016) Serena Stanga et al.   Aging-US

Neuroprotective effects of Liriope platyphylla extract against hydrogen peroxide-induced cytotoxicity in human neuroblastoma SH-SY5Y cells

(2015) Hee Ra Park et al.   BMC Complementary and Alternative Medicine

TMEM175 Is an Organelle K + Channel Regulating Lysosomal Function

(2015) Chunlei Cang et al.   CELL

Neuroprotective Effects of Ginkgolide B Against Ischemic Stroke: A Review of Current Literature

(2015) Seyed Nabavi et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

TFEB Participates in the Aβ-Induced Pathogenesis of Alzheimer's Disease by Regulating the Autophagy-Lysosome Pathway

(2015) Yi-dan Zhang et al.   DNA AND CELL BIOLOGY

Apigenin protects blood–brain barrier and ameliorates early brain injury by inhibiting TLR4-mediated inflammatory pathway in subarachnoid hemorrhage rats

(2015) Tingting Zhang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Optimized curcumin formulations for the treatment of Alzheimer's disease: A patent evaluation

(2015) Abolfazl Shakeri et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Signaling pathway of MAPK/ERK in cell proliferation, differentiation, migration, senescence and apoptosis

(2015) Yu Sun et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Region-specific dendritic simplification induced by Aβ, mediated by tau via dysregulation of microtubule dynamics: a mechanistic distinct event from other neurodegenerative processes

(2015) Nataliya Golovyashkina et al.   Molecular Neurodegeneration

Pharmacological Chaperone Therapy: Preclinical Development, Clinical Translation, and Prospects for the Treatment of Lysosomal Storage Disorders

(2015) Giancarlo Parenti et al.   MOLECULAR THERAPY

Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB

(2015) Diego L. Medina et al.   NATURE CELL BIOLOGY

Resveratrol exerts anti-inflammatory and neuroprotective effects to prevent memory deficits in rats exposed to chronic unpredictable mild stress

(2015) Yusufhan Yazir et al.   PHYSIOLOGY & BEHAVIOR

Up-regulation of lysosomal TRPML1 channels is essential for lysosomal adaptation to nutrient starvation

(2015) Wuyang Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of curcuminoids on oxidative stress: A systematic review and meta-analysis of randomized controlled trials

(2015) Amirhossein Sahebkar et al.   Journal of Functional Foods

Lysosomal mTORC2/PHLPP1/Akt axis: a new point of control of chaperone-mediated autophagy

(2015) Esperanza Arias   Oncotarget

Presenilin 1 Maintains Lysosomal Ca2+ Homeostasis via TRPML1 by Regulating vATPase-Mediated Lysosome Acidification

(2015) Ju-Hyun Lee et al.   Cell Reports

20(S)-Ginsenoside Rg3 is a novel inhibitor of autophagy and sensitizes hepatocellular carcinoma to doxorubicin

(2015) Dong-Gun Kim et al.   Oncotarget

The role of microglia in human disease: therapeutic tool or target?

(2014) Nathalie Cartier et al.   ACTA NEUROPATHOLOGICA

Neurodegenerative lysosomal disorders: A continuum from development to late age

(2014) Ralph A. Nixon et al.   Autophagy

Effects of curcumin on learning and memory deficits, BDNF, and ERK protein expression in rats exposed to chronic unpredictable stress

(2014) Dexiang Liu et al.   BEHAVIOURAL BRAIN RESEARCH

6-Shogaol, an active constituent of ginger, attenuates neuroinflammation and cognitive deficits in animal models of dementia

(2014) Minho Moon et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Inhibition of TNF-α-Mediated NF-κB Transcriptional Activity by Dammarane-Type Ginsenosides from Steamed Flower Buds of Panax ginseng in HepG2 and SK-Hep1 Cells

(2014) Kyoungwon Cho et al.   Biomolecules & Therapeutics

The Mechanistic Links Between Proteasome Activity, Aging and Agerelated Diseases

(2014) Isabel Saez et al.   CURRENT GENOMICS

Galantamine, an acetylcholinesterase inhibitor, reduces brain damage induced by hypoxia-ischemia in newborn rats

(2014) Seishi Furukawa et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Huperzine A Ameliorates Cognitive Deficits in Streptozotocin-Induced Diabetic Rats

(2014) Xiao-Yuan Mao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Resveratrol Induces the Expression of Interleukin-10 and Brain-Derived Neurotrophic Factor in BV2 Microglia under Hypoxia

(2014) Juhyun Song et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mulberroside a protects against ischemic impairment in primary culture of rat cortical neurons after oxygen-glucose deprivation followed by reperfusion

(2014) Cai-Ping Wang et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Curcumin as a wound healing agent

(2014) Dania Akbik et al.   LIFE SCIENCES

Protective Effect of Naringenin in Experimental Ischemic Stroke: Down-Regulated NOD2, RIP2, NF-κB, MMP-9 and Up-Regulated Claudin-5 Expression

(2014) Xue Bai et al.   NEUROCHEMICAL RESEARCH

The Nutrient-Responsive Transcription Factor TFE3 Promotes Autophagy, Lysosomal Biogenesis, and Clearance of Cellular Debris

(2014) J. A. Martina et al.   Science Signaling

The role of protein clearance mechanisms in organismal ageing and age-related diseases

(2014) David Vilchez et al.   Nature Communications

Antisense Oligonucleotide-mediated Suppression of Muscle Glycogen Synthase 1 Synthesis as an Approach for Substrate Reduction Therapy of Pompe Disease

(2014) Nicholas P Clayton et al.   Molecular Therapy-Nucleic Acids

Quinic acid derivatives from Pimpinella brachycarpa exert anti-neuroinflammatory activity in lipopolysaccharide-induced microglia

(2013) Seung Young Lee et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Novel NGF-potentiating limonoids from the fruits of Melia toosendan

(2013) Qiong Zhang et al.   FITOTERAPIA

Effects of C-glycosylation on anti-diabetic, anti-Alzheimer’s disease and anti-inflammatory potential of apigenin

(2013) Jae Sue Choi et al.   FOOD AND CHEMICAL TOXICOLOGY

Anti-inflammatory effects of prosapogenin III from the dried roots ofLiriope platyphyllain LPS-stimulated RAW264.7 cells

(2013) Yunkyung Han et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Bioactive Lignans from the Trunk of Abies holophylla

(2013) Chung Sub Kim et al.   JOURNAL OF NATURAL PRODUCTS

Free and nanoencapsulated curcumin suppress β-amyloid-induced cognitive impairments in rats: Involvement of BDNF and Akt/GSK-3β signaling pathway

(2013) Juliana B. Hoppe et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Naringenin protects against 6-OHDA-induced neurotoxicity via activation of the Nrf2/ARE signaling pathway

(2013) Haiyan Lou et al.   NEUROPHARMACOLOGY

Methyl angolensate and mexicanolide-type limonoids from the seeds of Cipadessa baccifera

(2013) Bandi Siva et al.   PHYTOCHEMISTRY

Comment on “Berberine and Its Emerging Benefits in Psychiatric Conditions Especially Alzheimer's Disease”

(2013) Shailendra Kapoor   TheScientificWorldJOURNAL

Transport of active flavonoids, based on cytotoxicity and lipophilicity: An evaluation using the blood–brain barrier cell and Caco-2 cell models

(2013) Yuya Yang et al.   TOXICOLOGY IN VITRO

Autophagic/lysosomal dysfunction in Alzheimer’s disease

(2013) Miranda E Orr et al.   Alzheimers Research & Therapy

Ginsenoside Rd inhibits the expressions of iNOS and COX-2 by suppressing NF-κB in LPS-stimulated RAW264.7 cells and mouse liver

(2013) Dae Hyun Kim et al.   Journal of Ginseng Research

Lysosomal dysfunction causes neurodegeneration in mucolipidosis II ‘knock-in’ mice

(2012) K. Kollmann et al.   BRAIN

Ginger in the Prevention of Nausea and Vomiting: A Review

(2012) Princy Louis Palatty et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Resveratrol Attenuates Obesity-Associated Peripheral and Central Inflammation and Improves Memory Deficit in Mice Fed a High-Fat Diet

(2012) B. T. Jeon et al.   DIABETES

A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB

(2012) Carmine Settembre et al.   EMBO JOURNAL

Inhibition of NF-κB activation is associated with anti-inflammatory and anti-apoptotic effects of Ginkgolide B in a mouse model of cerebral ischemia/reperfusion injury

(2012) Jin-Hua Gu et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Effects of [6]-shogaol on cholinergic signaling in HT22 cells following neuronal damage induced by hydrogen peroxide

(2012) Sehwan Shim et al.   FOOD AND CHEMICAL TOXICOLOGY

C-dideoxyhexosyl flavones from the stems and leaves of Passiflora edulis Sims

(2012) Fengqing Xu et al.   FOOD CHEMISTRY

Zingiber officinale (Ginger) as an Anti-Emetic in Cancer Chemotherapy: A Review

(2012) Raghavendra Haniadka et al.   JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE

Lysosomal storage disorders: The cellular impact of lysosomal dysfunction

(2012) Frances M. Platt et al.   JOURNAL OF CELL BIOLOGY

Life or death: Neuroprotective and anticancer effects of quercetin

(2012) Federico Dajas   JOURNAL OF ETHNOPHARMACOLOGY

Berberine suppresses amyloid-beta-induced inflammatory response in microglia by inhibiting nuclear factor-kappaB and mitogen-activated protein kinase signalling pathways

(2012) Liyun Jia et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Phellodendron amurenseand Its Major Alkaloid Compound, Berberine Ameliorates Scopolamine-Induced Neuronal Impairment and Memory Dysfunction in Rats

(2012) Bombi Lee et al.   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

Berberine ameliorates β-amyloid pathology, gliosis, and cognitive impairment in an Alzheimer's disease transgenic mouse model

(2012) Siva Sundara Kumar Durairajan et al.   NEUROBIOLOGY OF AGING

6-Shogaol, a ginger product, modulates neuroinflammation: A new approach to neuroprotection

(2012) Sang Keun Ha et al.   NEUROPHARMACOLOGY

Neuroprotective effect of naringenin is mediated through suppression of NF-κB signaling pathway in experimental stroke

(2012) S.S. Raza et al.   NEUROSCIENCE

Autophagy and lysosomal dysfunction as emerging mechanisms of nanomaterial toxicity

(2012) Stephan T Stern et al.   Particle and Fibre Toxicology

Astrocyte dysfunction triggers neurodegeneration in a lysosomal storage disorder

(2012) C. Di Malta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Transcription Factor TFEB Links mTORC1 Signaling to Transcriptional Control of Lysosome Homeostasis

(2012) A. Roczniak-Ferguson et al.   Science Signaling

Ayurvedic medicinal plants for Alzheimer's disease: a review

(2012) Rammohan V Rao et al.   Alzheimers Research & Therapy

Neuroprotective properties of Melissa officinalis after hypoxic-ischemic injury both in vitro and in vivo

(2012) Mohammad Bayat et al.   DARU-Journal of Pharmaceutical Sciences

Decreased Proteasomal Activity Causes Age-Related Phenotypes and Promotes the Development of Metabolic Abnormalities

(2011) Utano Tomaru et al.   AMERICAN JOURNAL OF PATHOLOGY

Endoplasmic reticulum is a main localization site of mTORC2

(2011) Delphine R. Boulbés et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Benzenediol-berberine hybrids: Multifunctional agents for Alzheimer’s disease

(2011) Huailei Jiang et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Decrease in the production of beta-amyloid by berberine inhibition of the expression of beta-secretase in HEK293 cells

(2011) Feiqi Zhu et al.   BMC NEUROSCIENCE

DNA-protective effects of quercetin or naringenin in alloxan-induced diabetic mice

(2011) Nada Oršolić et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Curcuminoids Promote Neurite Outgrowth in PC12 Cells through MAPK/ERK- and PKC-Dependent Pathways

(2011) Kuo-Kai Liao et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Consumer Acceptance of Ginseng Food Products

(2011) Hee Sook Chung et al.   JOURNAL OF FOOD SCIENCE

Sesquiterpenoids and triterpenoids from Abies holophylla and their bioactivities

(2011) Jia-Han Xia et al.   PHYTOCHEMISTRY

Spinster is required for autophagic lysosome reformation and mTOR reactivation following starvation

(2011) Y. Rong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TFEB Links Autophagy to Lysosomal Biogenesis

(2011) C. Settembre et al.   SCIENCE

Protective effect of quercetin against intracerebral streptozotocin induced reduction in cerebral blood flow and impairment of memory in mice

(2010) Santoshkumar Tota et al.   BEHAVIOURAL BRAIN RESEARCH

Quercetin and rutin prevent scopolamine-induced memory impairment in zebrafish

(2010) S.K. Richetti et al.   BEHAVIOURAL BRAIN RESEARCH

Ginkgolide B protects hippocampal neurons from apoptosis induced by beta-amyloid 25–35 partly via up-regulation of brain-derived neurotrophic factor

(2010) Qian Xiao et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

TPCs: Endolysosomal channels for Ca2+ mobilization from acidic organelles triggered by NAADP

(2010) Michael X. Zhu et al.   FEBS LETTERS

Molecular mechanisms for curcumin benefits against ischemic injury

(2010) Amirhossein Sahebkar   FERTILITY AND STERILITY

Rosmarinus officinalis polyphenols activate cholinergic activities in PC12 cells through phosphorylation of ERK1/2

(2010) Abdelfatteh El Omri et al.   JOURNAL OF ETHNOPHARMACOLOGY

Inhibition of TNF-α-induced adhesion molecule expression by diosgenin in mouse vascular smooth muscle cells via downregulation of the MAPK, Akt and NF-κB signaling pathways

(2010) Ko-Woon Choi et al.   VASCULAR PHARMACOLOGY

Anti-hepatitis B virus activity of chlorogenic acid, quinic acid and caffeic acid in vivo and in vitro

(2009) Gui-Feng Wang et al.   ANTIVIRAL RESEARCH

Blood brain barrier permeability and therapeutic time window of Ginkgolide B in ischemia–reperfusion injury

(2009) Weirong Fang et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Resveratrol prevents memory deficits and the increase in acetylcholinesterase activity in streptozotocin-induced diabetic rats

(2009) Roberta Schmatz et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Mitochondrial control of autophagic lysosomal pathway in Alzheimer's disease

(2009) S.M. Cardoso et al.   EXPERIMENTAL NEUROLOGY

Diosgenin attenuates inflammatory changes in the interaction between adipocytes and macrophages

(2009) Shizuka Hirai et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function

(2009) Paul Saftig et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The acid test: the discovery of two-pore channels (TPCs) as NAADP-gated endolysosomal Ca2+ release channels

(2009) Antony Galione et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Alzheimer's-related endosome dysfunction in Down syndrome is A -independent but requires APP and is reversed by BACE-1 inhibition

(2009) Y. Jiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lysosomal disorders: From storage to cellular damage

(2008) Andrea Ballabio et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Anti-inflammatory Activity of Prosapogenin Methyl Ester of Platycodin D via Nuclear Factor-kappaB Pathway Inhibition

(2008) Ji Won Chung et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Prevention of Inflammation-Mediated Neurotoxicity by Rg3 and Its Role in Microglial Activation

(2008) Seong Soo Joo et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

The role of autophagy-lysosome pathway in neurodegeneration associated with Parkinson's disease

(2008) T. Pan et al.   BRAIN

Resveratrol: A Natural Compound with Pharmacological Potential in Neurodegenerative Diseases

(2008) Héctor I. Rocha-González et al.   CNS Neuroscience & Therapeutics

Tomatidine inhibits iNOS and COX-2 through suppression of NF-κB and JNK pathways in LPS-stimulated mouse macrophages

(2008) Feng-Lan Chiu et al.   FEBS LETTERS

The Aqueous Extracts of Passiflora alata and Passiflora edulis Reduce Anxiety-Related Behaviors Without Affecting Memory Process in Rats

(2008) Paulo R. Barbosa et al.   JOURNAL OF MEDICINAL FOOD

Huperzine A exhibits anti-inflammatory and neuroprotective effects in a rat model of transient focal cerebral ischemia

(2008) Zhi-Fei Wang et al.   JOURNAL OF NEUROCHEMISTRY

Ginkgolides protect against amyloid-β1–42-mediated synapse damage in vitro

(2008) Clive Bate et al.   Molecular Neurodegeneration

6-Shogaol suppressed lipopolysaccharide-induced up-expression of iNOS and COX-2 in murine macrophages

(2008) Min-Hsiung Pan et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Evaluation of plasma Aβ40 and Aβ42 as predictors of conversion to Alzheimer's disease in patients with mild cognitive impairment

(2008) Oskar Hansson et al.   NEUROBIOLOGY OF AGING

Antioxidant Effects of Different Extracts from Melissa officinalis, Matricaria recutita and Cymbopogon citratus

(2008) Romaiana Picada Pereira et al.   NEUROCHEMICAL RESEARCH

Inhibitory effect of curcuminoids on acetylcholinesterase activity and attenuation of scopolamine-induced amnesia may explain medicinal use of turmeric in Alzheimer's disease

(2008) Touqeer Ahmed et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

High-dose galantamine augmentation inferior to placebo on attention, inhibitory control and working memory performance in nonsmokers with schizophrenia

(2008) M DYER et al.   SCHIZOPHRENIA RESEARCH