Region-specific dendritic simplification induced by Aβ, mediated by tau via dysregulation of microtubule dynamics: a mechanistic distinct event from other neurodegenerative processes

A RhoA Signaling Pathway Regulates Dendritic Golgi Outpost Formation

(2015) Gonzalo Quassollo et al.   CURRENT BIOLOGY

Intrinsically disordered proteins and their (disordered) proteomes in neurodegenerative disorders

(2015) Vladimir N. Uversky   Frontiers in Aging Neuroscience

Microtubule-associated protein tau as a therapeutic target in Alzheimer's disease

(2014) Khalid Iqbal et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

The tubulin code: Molecular components, readout mechanisms, and functions

(2014) Carsten Janke   JOURNAL OF CELL BIOLOGY

Brain-Penetrant, Orally Bioavailable Microtubule-Stabilizing Small Molecules Are Potential Candidate Therapeutics for Alzheimer’s Disease and Related Tauopathies

(2014) Kevin Lou et al.   JOURNAL OF MEDICINAL CHEMISTRY

Single-molecule tracking of tau reveals fast kiss-and-hop interaction with microtubules in living neurons

(2014) Dennis Janning et al.   MOLECULAR BIOLOGY OF THE CELL

GluN2A and GluN2B subunit-containing NMDA receptors in hippocampal plasticity

(2013) O. A. Shipton et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

NMDA receptor subunit composition determines beta-amyloid-induced neurodegeneration and synaptic loss

(2013) C Tackenberg et al.   Cell Death & Disease

The role of small GTPases in neuronal morphogenesis and polarity

(2012) Christian Gonzalez-Billault et al.   Cytoskeleton

Hyperphosphorylation of Tau Induced by Naturally Secreted Amyloid-β at Nanomolar Concentrations Is Modulated by Insulin-dependent Akt-GSK3β Signaling Pathway

(2012) Takayoshi Tokutake et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The frontotemporal dementia mutation R406W blocks tau’s interaction with the membrane in an annexin A2–dependent manner

(2011) Anne Gauthier-Kemper et al.   JOURNAL OF CELL BIOLOGY

Pitavastatin decreases tau levels via the inactivation of Rho/ROCK

(2011) Tadanori Hamano et al.   NEUROBIOLOGY OF AGING

The NMDA receptor co-agonists, d-serine and glycine, regulate neuronal dendritic architecture in the somatosensory cortex

(2011) Darrick T. Balu et al.   NEUROBIOLOGY OF DISEASE

Soluble amyloid  -protein dimers isolated from Alzheimer cortex directly induce Tau hyperphosphorylation and neuritic degeneration

(2011) M. Jin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Changes in dendritic complexity and spine morphology in transgenic mice expressing human wild-type tau

(2010) Dara L. Dickstein et al.   Brain Structure & Function

Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models

(2010) Lars M. Ittner et al.   CELL

Tau in Alzheimer Disease and Related Tauopathies

(2010) K. Iqbal et al.   Current Alzheimer Research

Reimagining Alzheimer's Disease--An Age-Based Hypothesis

(2010) K. Herrup   JOURNAL OF NEUROSCIENCE

Epothilone D Improves Microtubule Density, Axonal Integrity, and Cognition in a Transgenic Mouse Model of Tauopathy

(2010) K. R. Brunden et al.   JOURNAL OF NEUROSCIENCE

Amyloid   Induces the Morphological Neurodegenerative Triad of Spine Loss, Dendritic Simplification, and Neuritic Dystrophies through Calcineurin Activation

(2010) H.-Y. Wu et al.   JOURNAL OF NEUROSCIENCE

A  Oligomers Cause Localized Ca2+ Elevation, Missorting of Endogenous Tau into Dendrites, Tau Phosphorylation, and Destruction of Microtubules and Spines

(2010) H. Zempel et al.   JOURNAL OF NEUROSCIENCE

Divergent Pathways Mediate Spine Alterations and Cell Death Induced by Amyloid- , Wild-Type Tau, and R406W Tau

(2009) C. Tackenberg et al.   JOURNAL OF NEUROSCIENCE

Microtubule assembly, organization and dynamics in axons and dendrites

(2009) Cecilia Conde et al.   NATURE REVIEWS NEUROSCIENCE

Experimental epothilone B neurotoxicity: Results of in vitro and in vivo studies

(2009) Alessia Chiorazzi et al.   NEUROBIOLOGY OF DISEASE

Animal models of Alzheimer's disease and frontotemporal dementia

(2008) Jürgen Götz et al.   NATURE REVIEWS NEUROSCIENCE

Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain

(2003) H. F. Dovey et al.   JOURNAL OF NEUROCHEMISTRY