Microtubule Dysfunction: A Common Feature of Neurodegenerative Diseases
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Microtubule Dysfunction: A Common Feature of Neurodegenerative Diseases
Authors
Keywords
-
Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 21, Issue 19, Pages 7354
Publisher
MDPI AG
Online
2020-10-05
DOI
10.3390/ijms21197354
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- TUBB Variants Underlying Different Phenotypes Result in Altered Vesicle Trafficking and Microtubule Dynamics
- (2020) Antonella Sferra et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Tubulin polyglutamylation is a general traffic-control mechanism in hippocampal neurons
- (2020) Satish Bodakuntla et al. JOURNAL OF CELL SCIENCE
- Initiation and propagation of α-synuclein aggregation in the nervous system
- (2020) Baraa A. Hijaz et al. Molecular Neurodegeneration
- De novo mutations of TUBB2A cause infantile-onset epilepsy and developmental delay
- (2020) Shuying Cai et al. JOURNAL OF HUMAN GENETICS
- TUBB4A mutations result in both glial and neuronal degeneration in an H-ABC leukodystrophy mouse model
- (2020) Sunetra Sase et al. eLife
- Microtubule Plus End Dynamics − Do We Know How Microtubules Grow?
- (2019) Jeffrey van Haren et al. BIOESSAYS
- Spectrum of clinical heterogeneity of β-tubulin TUBB5 gene mutations
- (2019) I. Madrigal et al. GENE
- Microtubule minus-end regulation at a glance
- (2019) Anna Akhmanova et al. JOURNAL OF CELL SCIENCE
- Differential requirements of tubulin genes in mammalian forebrain development
- (2019) Elizabeth Bittermann et al. PLoS Genetics
- Motor protein binding and mitochondrial transport are altered by pathogenic TUBB4A variants
- (2019) Franca Vulinovic et al. HUMAN MUTATION
- The model of local axon homeostasis - explaining the role and regulation of microtubule bundles in axon maintenance and pathology
- (2019) Ines Hahn et al. Neural Development
- Loss of Parkin contributes to mitochondrial turnover and dopaminergic neuronal loss in aged mice
- (2019) Sachiko Noda et al. NEUROBIOLOGY OF DISEASE
- Dystonia-4 (DYT4)-associated TUBB4A mutants exhibit disorganized microtubule networks and inhibit neuronal process growth
- (2018) Natsumi Watanabe et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Tubulin Posttranslational Modifications and Emerging Links to Human Disease
- (2018) Maria M. Magiera et al. CELL
- Intrafamiliar clinical variability of circumferential skin creases Kunze type caused by a novel heterozygous mutation of N-terminal TUBB gene
- (2018) M.L. Dentici et al. CLINICAL GENETICS
- Tubulin genes and malformations of cortical development
- (2018) Romina Romaniello et al. European Journal of Medical Genetics
- Defective kinesin binding of TUBB2A causes progressive spastic ataxia syndrome resembling sacsinopathy
- (2018) Antonella Sferra et al. HUMAN MOLECULAR GENETICS
- Functionally specific binding regions of microtubule-associated protein 2c exhibit distinct conformations and dynamics
- (2018) Kateřina Melková et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Parkin absence accelerates microtubule aging in dopaminergic neurons
- (2018) Daniele Cartelli et al. NEUROBIOLOGY OF AGING
- Hypomyelinating disorders in China: The clinical and genetic heterogeneity in 119 patients
- (2018) Haoran Ji et al. PLoS One
- Human β-Tubulin Isotypes Can Regulate Microtubule Protofilament Number and Stability
- (2018) Shih-Chieh Ti et al. DEVELOPMENTAL CELL
- Intracellular Amyloid-β Accumulation in Calcium-Binding Protein-Deficient Neurons Leads to Amyloid-β Plaque Formation in Animal Model of Alzheimer's Disease
- (2018) Minho Moon et al. JOURNAL OF ALZHEIMERS DISEASE
- Repositioning Microtubule Stabilizing Drugs for Brain Disorders
- (2018) Artemis Varidaki et al. Frontiers in Cellular Neuroscience
- The HAUS Complex Is a Key Regulator of Non-centrosomal Microtubule Organization during Neuronal Development
- (2018) Inês Cunha-Ferreira et al. Cell Reports
- Neuronal-Specific TUBB3 Is Not Required for Normal Neuronal Function but Is Essential for Timely Axon Regeneration
- (2018) Alban Latremoliere et al. Cell Reports
- Loss of tubulin deglutamylase CCP1 causes infantile‐onset neurodegeneration
- (2018) Vandana Shashi et al. EMBO JOURNAL
- Excessive tubulin polyglutamylation causes neurodegeneration and perturbs neuronal transport
- (2018) Maria M Magiera et al. EMBO JOURNAL
- De Novo Mutated TUBB2B Associated Pachygyria Diagnosed by Medical Exome Sequencing and Long-Range PCR
- (2018) Hui Wang et al. Fetal and Pediatric Pathology
- TUBA1A mutations identified in lissencephaly patients dominantly disrupt neuronal migration and impair dynein activity
- (2018) Jayne Aiken et al. HUMAN MOLECULAR GENETICS
- CCP1 promotes mitochondrial fusion and motility to prevent Purkinje cell neuron loss in pcd mice
- (2018) Stephen Gilmore-Hall et al. JOURNAL OF CELL BIOLOGY
- Severe TUBB4A-Related Hypomyelination With Atrophy of the Basal Ganglia and Cerebellum: Novel Neuropathological Findings
- (2018) Kristina M Joyal et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- A brain-penetrant triazolopyrimidine enhances microtubule-stability, reduces axonal dysfunction and decreases tau pathology in a mouse tauopathy model
- (2018) Bin Zhang et al. Molecular Neurodegeneration
- The HDAC6 Inhibitor Trichostatin A Acetylates Microtubules and Protects Axons From Excitotoxin-Induced Degeneration in a Compartmented Culture Model
- (2018) Kelsey Hanson et al. Frontiers in Neuroscience
- TUBB4A mutations result in specific neuronal and oligodendrocytic defects that closely match clinically distinct phenotypes
- (2017) Julian Curiel et al. HUMAN MOLECULAR GENETICS
- Tubulin Post-Translational Modifications and Microtubule Dynamics
- (2017) et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The tubulin code at a glance
- (2017) Sudarshan Gadadhar et al. JOURNAL OF CELL SCIENCE
- Polarity sorting of axonal microtubules: a computational study
- (2017) Erin M. Craig et al. MOLECULAR BIOLOGY OF THE CELL
- Two kinesins drive anterograde neuropeptide transport
- (2017) Angeline Lim et al. MOLECULAR BIOLOGY OF THE CELL
- Tubulin isoform composition tunes microtubule dynamics
- (2017) Annapurna Vemu et al. MOLECULAR BIOLOGY OF THE CELL
- ADNP/NAP dramatically increase microtubule end-binding protein–Tau interaction: a novel avenue for protection against tauopathy
- (2017) Y Ivashko-Pachima et al. MOLECULAR PSYCHIATRY
- Tubulin acetylation protects long-lived microtubules against mechanical ageing
- (2017) Didier Portran et al. NATURE CELL BIOLOGY
- Chemical and structural biology of protein lysine deacetylases
- (2017) Minoru YOSHIDA et al. PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES
- Identification of DmTTLL5 as a Major Tubulin Glutamylase in the Drosophila Nervous System
- (2017) Isabelle Devambez et al. Scientific Reports
- Cytoplasmic Dynein Transports Axonal Microtubules in a Polarity-Sorting Manner
- (2017) Anand N. Rao et al. Cell Reports
- The Neuroprotective Peptide NAP Does Not Directly Affect Polymerization or Dynamics of Reconstituted Neural Microtubules
- (2017) Mythili Yenjerla et al. JOURNAL OF ALZHEIMERS DISEASE
- Increase in α-tubulin modifications in the neuronal processes of hippocampal neurons in both kainic acid-induced epileptic seizure and Alzheimer’s disease
- (2017) Hang Thi Vu et al. Scientific Reports
- Human histone deacetylase 6 shows strong preference for tubulin dimers over assembled microtubules
- (2017) Lubica Skultetyova et al. Scientific Reports
- Graded Control of Microtubule Severing by Tubulin Glutamylation
- (2016) Max L. Valenstein et al. CELL
- Back to the tubule: microtubule dynamics in Parkinson’s disease
- (2016) Laura Pellegrini et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Microtubule plus-end tracking proteins in neuronal development
- (2016) Dieudonnée van de Willige et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Stability properties of neuronal microtubules
- (2016) Peter W. Baas et al. Cytoskeleton
- TUBB4A-related hypomyelinating leukodystrophy: New insights from a series of 12 patients
- (2016) Davide Tonduti et al. EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY
- Mice lacking α-tubulin acetyltransferase 1 are viable but display α-tubulin acetylation deficiency and dentate gyrus distortion.
- (2016) Go-Woon Kim et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ttll9−/−mice sperm flagella show shortening of doublet 7, reduction of doublet 5 polyglutamylation and a stall in beating
- (2016) Alu Konno et al. JOURNAL OF CELL SCIENCE
- SIRT2 inactivation reveals a subset of hyperacetylated perinuclear microtubules inaccessible to HDAC6
- (2016) Renate Hvidsten Skoge et al. JOURNAL OF CELL SCIENCE
- Regulation of Microtubule Assembly by Tau and not by Pin1
- (2016) Steffen Kutter et al. JOURNAL OF MOLECULAR BIOLOGY
- Early-onset progressive spastic paraplegia caused by a novel TUBB4A mutation: brain MRI and FDG-PET findings
- (2016) Anna Sagnelli et al. JOURNAL OF NEUROLOGY
- Dendrites In Vitro and In Vivo Contain Microtubules of Opposite Polarity and Axon Formation Correlates with Uniform Plus-End-Out Microtubule Orientation
- (2016) K. W. Yau et al. JOURNAL OF NEUROSCIENCE
- Congenital-onset spastic paraplegia in a patient with TUBB4A mutation and mild hypomyelination
- (2016) Francesco Nicita et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- GDP-to-GTP exchange on the microtubule end can contribute to the frequency of catastrophe
- (2016) Felipe-Andrés Piedra et al. MOLECULAR BIOLOGY OF THE CELL
- Microtubule Destabilization Paves the Way to Parkinson’s Disease
- (2016) D. Cartelli et al. MOLECULAR NEUROBIOLOGY
- Mechanism of microtubule lumen entry for the α-tubulin acetyltransferase enzyme αTAT1
- (2016) Courtney Coombes et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Non-centrosomal nucleation mediated by augmin organizes microtubules in post-mitotic neurons and controls axonal microtubule polarity
- (2016) Carlos Sánchez-Huertas et al. Nature Communications
- α-Synuclein is a Novel Microtubule Dynamase
- (2016) Daniele Cartelli et al. Scientific Reports
- αTAT1 controls longitudinal spreading of acetylation marks from open microtubules extremities
- (2016) Nathalie Ly et al. Scientific Reports
- Mutations in Either TUBB or MAPRE2 Cause Circumferential Skin Creases Kunze Type
- (2015) Mala Isrie et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Two uniqueTUBB3mutations cause both CFEOM3 and malformations of cortical development
- (2015) Mary C. Whitman et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Genetic heterogeneity in 26 infants with a hypomyelinating leukodystrophy
- (2015) Natsuko Arai-Ichinoi et al. HUMAN GENETICS
- Writing and Reading the Tubulin Code
- (2015) Ian Yu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The expression oftubb2bundergoes a developmental transition in murine cortical neurons
- (2015) Martin Breuss et al. JOURNAL OF COMPARATIVE NEUROLOGY
- Defects in Synaptic Plasticity, Reduced NMDA-Receptor Transport, and Instability of Postsynaptic Density Proteins in Mice Lacking Microtubule-Associated Protein 1A
- (2015) Yosuke Takei et al. JOURNAL OF NEUROSCIENCE
- Mosaic dominantTUBB4Amutation in an inbred family with complicated hereditary spastic paraplegia
- (2015) Dahlia Kancheva et al. MOVEMENT DISORDERS
- Lineage specificity of primary cilia in the mouse embryo
- (2015) Fiona K. Bangs et al. NATURE CELL BIOLOGY
- Building the Neuronal Microtubule Cytoskeleton
- (2015) Lukas C. Kapitein et al. NEURON
- Post-translational modifications of tubulin: pathways to functional diversity of microtubules
- (2015) Yuyu Song et al. TRENDS IN CELL BIOLOGY
- Tubulinopathies and Their Brain Malformation Syndromes: EveryTUBon Its Own Bottom
- (2015) Bernard S. Chang Epilepsy Currents
- Deacetylation of α-tubulin and cortactin is required for HDAC6 to trigger ciliary disassembly
- (2015) Jie Ran et al. Scientific Reports
- Interplay between kinesin-1 and cortical dynein during axonal outgrowth and microtubule organization in Drosophila neurons
- (2015) Urko del Castillo et al. eLife
- Posttranslational modifications of α-tubulin in alzheimer disease
- (2015) Fan Zhang et al. Translational Neurodegeneration
- The Sirtuin-2 Inhibitor AK7 Is Neuroprotective in Models of Parkinson’s Disease but Not Amyotrophic Lateral Sclerosis and Cerebral Ischemia
- (2015) Xiqun Chen et al. PLoS One
- De Novo Mutations in the Beta-Tubulin Gene TUBB2A Cause Simplified Gyral Patterning and Infantile-Onset Epilepsy
- (2014) Thomas D. Cushion et al. AMERICAN JOURNAL OF HUMAN GENETICS
- NovelTUBB4Amutations and expansion of the neuroimaging phenotype of hypomyelination with atrophy of the basal ganglia and cerebellum (H-ABC)
- (2014) Carlos Ferreira et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Alzheimer disease therapeutics: Focus on the disease and not just plaques and tangles
- (2014) Khalid Iqbal et al. BIOCHEMICAL PHARMACOLOGY
- The wide spectrum of tubulinopathies: what are the key features for the diagnosis?
- (2014) Nadia Bahi-Buisson et al. BRAIN
- Hypomyelination with atrophy of the basal ganglia and cerebellum: further delineation of the phenotype and genotype–phenotype correlation
- (2014) Eline M. Hamilton et al. BRAIN
- TUBB4A novel mutation reinforces the genotype–phenotype correlation of hypomyelination with atrophy of the basal ganglia and cerebellum
- (2014) Daniel Carvalho et al. BRAIN
- Molecular Basis for Age-Dependent Microtubule Acetylation by Tubulin Acetyltransferase
- (2014) Agnieszka Szyk et al. CELL
- Post-translational modifications of tubulin
- (2014) Maria M. Magiera et al. CURRENT BIOLOGY
- Connecting the Cytoskeleton to the Endoplasmic Reticulum and Golgi
- (2014) Pinar S. Gurel et al. CURRENT BIOLOGY
- Aneuploidy: implications for protein homeostasis and disease
- (2014) A. B. Oromendia et al. Disease Models & Mechanisms
- TUBB5 and its disease-associated mutations influence the terminal differentiation and dendritic spine densities of cerebral cortical neurons
- (2014) Linh Ngo et al. HUMAN MOLECULAR GENETICS
- The cytosolic carboxypeptidases CCP2 and CCP3 catalyze posttranslational removal of acidic amino acids
- (2014) Olivia Tort et al. MOLECULAR BIOLOGY OF THE CELL
- A family with axonal sensorimotor polyneuropathy with TUBB3 mutation
- (2014) YOUNG BIN HONG et al. Molecular Medicine Reports
- Regulation of microtubule motors by tubulin isotypes and post-translational modifications
- (2014) Minhajuddin Sirajuddin et al. NATURE CELL BIOLOGY
- TUBB4A de novo mutations cause isolated hypomyelination
- (2014) A. Pizzino et al. NEUROLOGY
- Expanding the phenotypic spectrum of TUBB4A-associated hypomyelinating leukoencephalopathies
- (2014) S. Miyatake et al. NEUROLOGY
- Exome-wide Rare Variant Analysis Identifies TUBA4A Mutations Associated with Familial ALS
- (2014) Bradley N. Smith et al. NEURON
- Clinical Exome Sequencing Identifies a Novel TUBB4A Mutation in a Child With Static Hypomyelinating Leukodystrophy
- (2014) Shawn M. Purnell et al. PEDIATRIC NEUROLOGY
- Parkin Mutations Reduce the Complexity of Neuronal Processes in iPSC-Derived Human Neurons
- (2014) Yong Ren et al. STEM CELLS
- Increasing microtubule acetylation rescues axonal transport and locomotor deficits caused by LRRK2 Roc-COR domain mutations
- (2014) Vinay K. Godena et al. Nature Communications
- Molecular evolution and functional divergence of tubulin superfamily in the fungal tree of life
- (2014) Zhongtao Zhao et al. Scientific Reports
- Histone deacetylase 6 inhibition improves memory and reduces total tau levels in a mouse model of tau deposition
- (2014) Maj-Linda Selenica et al. Alzheimers Research & Therapy
- X chromosome aneuploidy in the Alzheimer’s disease brain
- (2014) Yuri B Yurov et al. Molecular Cytogenetics
- The role of dynamic instability in microtubule organization
- (2014) Tetsuya Horio et al. Frontiers in Plant Science
- Low dose tubulin-binding drugs rescue peroxisome trafficking deficit in patient-derived stem cells in Hereditary Spastic Paraplegia
- (2014) Y. Fan et al. Biology Open
- Mutations in tubulin genes are frequent causes of various foetal malformations of cortical development including microlissencephaly
- (2014) Catherine Fallet-Bianco et al. Acta Neuropathologica Communications
- LRRK2 phosphorylates novel tau epitopes and promotes tauopathy
- (2013) Rachel M. Bailey et al. ACTA NEUROPATHOLOGICA
- A De Novo Mutation in the β-Tubulin Gene TUBB4A Results in the Leukoencephalopathy Hypomyelination with Atrophy of the Basal Ganglia and Cerebellum
- (2013) Cas Simons et al. AMERICAN JOURNAL OF HUMAN GENETICS
- A Double-Blind, Placebo-Controlled, Ascending-Dose, Randomized Study to Evaluate the Safety, Tolerability and Effects on Cognition of AL-108 after 12 Weeks of Intranasal Administration in Subjects with Mild Cognitive Impairment
- (2013) Bruce H. Morimoto et al. DEMENTIA AND GERIATRIC COGNITIVE DISORDERS
- Amyloid-β oligomers induce synaptic damage via Tau-dependent microtubule severing by TTLL6 and spastin
- (2013) Hans Zempel et al. EMBO JOURNAL
- β-Tubulin mutations that cause severe neuropathies disrupt axonal transport
- (2013) Shinsuke Niwa et al. EMBO JOURNAL
- MAP1B-dependent Rac activation is required for AMPA receptor endocytosis during long-term depression
- (2013) Marion Benoist et al. EMBO JOURNAL
- Kif3a interacts with Dynactin subunit p150Glued to organize centriole subdistal appendages
- (2013) Andrew Kodani et al. EMBO JOURNAL
- Description of a novel TUBA1A mutation in Arg-390 associated with asymmetrical polymicrogyria and mid-hindbrain dysgenesis
- (2013) Ginevra Zanni et al. EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY
- Hdac6 deletion delays disease progression in the SOD1G93A mouse model of ALS
- (2013) Ines Taes et al. HUMAN MOLECULAR GENETICS
- A Direct Interaction between Leucine-rich Repeat Kinase 2 and Specific β-Tubulin Isoforms Regulates Tubulin Acetylation
- (2013) Bernard M. H. Law et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Tubulin glycylases and glutamylases have distinct functions in stabilization and motility of ependymal cilia
- (2013) Montserrat Bosch Grau et al. JOURNAL OF CELL BIOLOGY
- Microtubules in neurons as information carriers
- (2013) Erik W. Dent et al. JOURNAL OF NEUROCHEMISTRY
- Tau pathology and neurodegeneration
- (2013) Maria Grazia Spillantini et al. LANCET NEUROLOGY
- Effects of tubulin acetylation and tubulin acetyltransferase binding on microtubule structure
- (2013) Stuart C. Howes et al. MOLECULAR BIOLOGY OF THE CELL
- HDAC6 as a target for neurodegenerative diseases: what makes it different from the other HDACs?
- (2013) Claudia Simões-Pires et al. Molecular Neurodegeneration
- NAP (davunetide) rescues neuronal dysfunction in a Drosophila model of tauopathy
- (2013) S Quraishe et al. MOLECULAR PSYCHIATRY
- Genetics of Parkinson's disease – state of the art, 2013
- (2013) Vincenzo Bonifati PARKINSONISM & RELATED DISORDERS
- Mitotic Spindle Defects and Chromosome Mis-Segregation Induced by LDL/Cholesterol—Implications for Niemann-Pick C1, Alzheimer’s Disease, and Atherosclerosis
- (2013) Antoneta Granic et al. PLoS One
- Profiling Murine Tau with 0N, 1N and 2N Isoform-Specific Antibodies in Brain and Peripheral Organs Reveals Distinct Subcellular Localization, with the 1N Isoform Being Enriched in the Nucleus
- (2013) Chang Liu et al. PLoS One
- HDAC6 mutations rescue human tau-induced microtubule defects in Drosophila
- (2013) Y. Xiong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Microtubule Alterations Occur Early in Experimental Parkinsonism and The Microtubule Stabilizer Epothilone D Is Neuroprotective
- (2013) Daniele Cartelli et al. Scientific Reports
- Ninein is essential for the maintenance of the cortical progenitor character by anchoring the centrosome to microtubules
- (2013) H. Shinohara et al. Biology Open
- Whispering dysphonia (DYT4 dystonia) is caused by a mutation in theTUBB4gene
- (2012) Katja Lohmann et al. ANNALS OF NEUROLOGY
- Mutations in the autoregulatory domain of β-tubulin 4a cause hereditary dystonia
- (2012) Joshua Hersheson et al. ANNALS OF NEUROLOGY
- Lissencephaly with marked ventricular dilation, agenesis of corpus callosum, and cerebellar hypoplasia caused by TUBA1A mutation
- (2012) Akihisa Okumura et al. BRAIN & DEVELOPMENT
- Genetically Separable Functions of the MEC-17 Tubulin Acetyltransferase Affect Microtubule Organization
- (2012) Irini Topalidou et al. CURRENT BIOLOGY
- A novel mutation in the β-tubulin gene TUBB2B associated with complex malformation of cortical development and deficits in axonal guidance
- (2012) ROMINA ROMANIELLO et al. DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY
- Reducing HDAC6 ameliorates cognitive deficits in a mouse model for Alzheimer's disease
- (2012) Nambirajan Govindarajan et al. EMBO Molecular Medicine
- Symmetric polymicrogyria and pachygyria associated with TUBB2B gene mutations
- (2012) Renzo Guerrini et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Expanding the spectrum of TUBA1A-related cortical dysgenesis to Polymicrogyria
- (2012) Karine Poirier et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- An inherited TUBB2B mutation alters a kinesin-binding site and causes polymicrogyria, CFEOM and axon dysinnervation
- (2012) Gustav Y. Cederquist et al. HUMAN MOLECULAR GENETICS
- Hyperdynamic Microtubules, Cognitive Deficits, and Pathology Are Improved in Tau Transgenic Mice with Low Doses of the Microtubule-Stabilizing Agent BMS-241027
- (2012) D. M. Barten et al. JOURNAL OF NEUROSCIENCE
- The Microtubule-Stabilizing Agent, Epothilone D, Reduces Axonal Dysfunction, Neurotoxicity, Cognitive Deficits, and Alzheimer-Like Pathology in an Interventional Study with Aged Tau Transgenic Mice
- (2012) B. Zhang et al. JOURNAL OF NEUROSCIENCE
- The many faces of α-synuclein: from structure and toxicity to therapeutic target
- (2012) Hilal A. Lashuel et al. NATURE REVIEWS NEUROSCIENCE
- Golgi Outposts Shape Dendrite Morphology by Functioning as Sites of Acentrosomal Microtubule Nucleation in Neurons
- (2012) Kassandra M. Ori-McKenney et al. NEURON
- LRRK2 Phosphorylates Tubulin-Associated Tau but Not the Free Molecule: LRRK2-Mediated Regulation of the Tau-Tubulin Association and Neurite Outgrowth
- (2012) Fumitaka Kawakami et al. PLoS One
- Correction: Microtubule Destabilization Is Shared by Genetic and Idiopathic Parkinson’s Disease Patient Fibroblasts
- (2012) Daniele Cartelli et al. PLoS One
- Dysfunction of microtubule-associated proteins of MAP2/tau family in Prion disease
- (2012) Jin Zhang et al. Prion
- Mutations in the β-Tubulin Gene TUBB5 Cause Microcephaly with Structural Brain Abnormalities
- (2012) Martin Breuss et al. Cell Reports
- The Sirtuin 2 Inhibitor AK-7 Is Neuroprotective in Huntington’s Disease Mouse Models
- (2012) Vanita Chopra et al. Cell Reports
- Chromosomal aneuploidy in the aging brain
- (2011) Francesca Faggioli et al. MECHANISMS OF AGEING AND DEVELOPMENT
- HDAC6 inhibitors reverse axonal loss in a mouse model of mutant HSPB1–induced Charcot-Marie-Tooth disease
- (2011) Constantin d'Ydewalle et al. NATURE MEDICINE
- Microtubule nucleation by γ-tubulin complexes
- (2011) Justin M. Kollman et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- TUBA1A mutations: From isolated lissencephaly to familial polymicrogyria
- (2011) A. C. Jansen et al. NEUROLOGY
- Selective Cell Death of Hyperploid Neurons in Alzheimer’s Disease
- (2010) Thomas Arendt et al. AMERICAN JOURNAL OF PATHOLOGY
- A Family of Protein-Deglutamylating Enzymes Associated with Neurodegeneration
- (2010) Krzysztof Rogowski et al. CELL
- Human TUBB3 Mutations Perturb Microtubule Dynamics, Kinesin Interactions, and Axon Guidance
- (2010) Max A. Tischfield et al. CELL
- Microtubule tip-interacting proteins: a view from both ends
- (2010) Kai Jiang et al. CURRENT OPINION IN CELL BIOLOGY
- Tumoral and tissue-specific expression of the major human β-tubulin isotypes
- (2010) Luis J. Leandro-García et al. Cytoskeleton
- Hooks and comets: The story of microtubule polarity orientation in the neuron
- (2010) Peter W. Baas et al. Developmental Neurobiology
- CCP1/Nna1 functions in protein turnover in mouse brain: Implications for cell death in Purkinje cell degeneration mice
- (2010) Iryna Berezniuk et al. FASEB JOURNAL
- Mutations in the neuronal β-tubulin subunit TUBB3 result in malformation of cortical development and neuronal migration defects
- (2010) Karine Poirier et al. HUMAN MOLECULAR GENETICS
- Identification of Tubulin Deglutamylase amongCaenorhabditis elegansand Mammalian Cytosolic Carboxypeptidases (CCPs)
- (2010) Yoshishige Kimura et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Polyglutamylation makes the cut
- (2010) Ben Short JOURNAL OF CELL BIOLOGY
- Tubulin polyglutamylation stimulates spastin-mediated microtubule severing
- (2010) Benjamin Lacroix et al. JOURNAL OF CELL BIOLOGY
- Expression of the embryonal isoform (0N/3R) of the microtubule associated protein tau in the adult rat central nervous system
- (2010) Torsten Bullmann et al. JOURNAL OF COMPARATIVE NEUROLOGY
- Epothilone D Improves Microtubule Density, Axonal Integrity, and Cognition in a Transgenic Mouse Model of Tauopathy
- (2010) K. R. Brunden et al. JOURNAL OF NEUROSCIENCE
- Rational Design and Simple Chemistry Yield a Superior, Neuroprotective HDAC6 Inhibitor, Tubastatin A
- (2010) Kyle V. Butler et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Cell mechanics and the cytoskeleton
- (2010) Daniel A. Fletcher et al. NATURE
- Mutation of the Variant α-Tubulin TUBA8 Results in Polymicrogyria with Optic Nerve Hypoplasia
- (2009) Mohammad R. Abdollahi et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Human Microtubule-Associated-Protein Tau Regulates the Number of Protofilaments in Microtubules: A Synchrotron X-Ray Scattering Study
- (2009) M.C. Choi et al. BIOPHYSICAL JOURNAL
- Addressing Alzheimers Disease Tangles: From NAP to AL-108
- (2009) Illana Gozes et al. Current Alzheimer Research
- Cytoskeletal dynamics in growth-cone steering
- (2009) S. Geraldo et al. JOURNAL OF CELL SCIENCE
- Leucine-rich repeat kinase 2 phosphorylates brain tubulin-beta isoforms and modulates microtubule stability - a point of convergence in Parkinsonian neurodegeneration?
- (2009) Frank Gillardon JOURNAL OF NEUROCHEMISTRY
- Mutations in the β-tubulin gene TUBB2B result in asymmetrical polymicrogyria
- (2009) Xavier Hubert Jaglin et al. NATURE GENETICS
- Microtubule assembly, organization and dynamics in axons and dendrites
- (2009) Cecilia Conde et al. NATURE REVIEWS NEUROSCIENCE
- NAP protects memory, increases soluble tau and reduces tau hyperphosphorylation in a tauopathy model
- (2009) Natalia Shiryaev et al. NEUROBIOLOGY OF DISEASE
- Parkin Protects Dopaminergic Neurons against Microtubule-depolymerizing Toxins by Attenuating Microtubule-associated Protein Kinase Activation
- (2008) Yong Ren et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Histone deacetylase 6 interacts with the microtubule-associated protein tau
- (2008) Huiping Ding et al. JOURNAL OF NEUROCHEMISTRY
- The Potential for -Structure in the Repeat Domain of Tau Protein Determines Aggregation, Synaptic Decay, Neuronal Loss, and Coassembly with Endogenous Tau in Inducible Mouse Models of Tauopathy
- (2008) M.-M. Mocanu et al. JOURNAL OF NEUROSCIENCE
- The Roc domain of leucine-rich repeat kinase 2 is sufficient for interaction with microtubules
- (2008) Payal N. Gandhi et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Microtubules Have Opposite Orientation in Axons and Dendrites of Drosophila Neurons
- (2008) Michelle C. Stone et al. MOLECULAR BIOLOGY OF THE CELL
- Complementary dimerization of microtubule-associated tau protein: Implications for microtubule bundling and tau-mediated pathogenesis
- (2008) K. J. Rosenberg et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Microtubule-associated protein tau in development, degeneration and protection of neurons
- (2008) Jian-Zhi Wang et al. PROGRESS IN NEUROBIOLOGY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started