ADNP/NAP dramatically increase microtubule end-binding protein–Tau interaction: a novel avenue for protection against tauopathy

The Neuroprotective Peptide NAP Does Not Directly Affect Polymerization or Dynamics of Reconstituted Neural Microtubules

(2017) Mythili Yenjerla et al.   JOURNAL OF ALZHEIMERS DISEASE

A genome-wide association study of bipolar disorder with comorbid eating disorder replicates the SOX2-OT region

(2016) Xiaohua Liu et al.   JOURNAL OF AFFECTIVE DISORDERS

Tau antagonizes end-binding protein tracking at microtubule ends through a phosphorylation-dependent mechanism

(2016) Sacnicte Ramirez-Rios et al.   MOLECULAR BIOLOGY OF THE CELL

Sexual divergence in microtubule function: the novel intranasal microtubule targeting SKIP normalizes axonal transport and enhances memory

(2016) N Amram et al.   MOLECULAR PSYCHIATRY

Alterations in Activity-Dependent Neuroprotective Protein in Sporadic and Experimental Parkinson’s Disease

(2016) Yaping Chu et al.   Journal of Parkinsons Disease

ADNP/ADNP2 expression in oligodendrocytes: implication for myelin-related neurodevelopment

(2015) Anna Malishkevich et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

The Compassionate Side of Neuroscience: Tony Sermone’s Undiagnosed Genetic Journey—ADNP Mutation

(2015) Illana Gozes et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Tau regulates the localization and function of End-binding proteins 1 and 3 in developing neuronal cells

(2015) Carmen Laura Sayas et al.   JOURNAL OF NEUROCHEMISTRY

Control of microtubule organization and dynamics: two ends in the limelight

(2015) Anna Akhmanova et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Effects of Paclitaxel and Eribulin in Mouse Sciatic Nerve: A Microtubule-Based Rationale for the Differential Induction of Chemotherapy-Induced Peripheral Neuropathy

(2015) Sarah J. Benbow et al.   NEUROTOXICITY RESEARCH

Risperidone and NAP protect cognition and normalize gene expression in a schizophrenia mouse model

(2015) Sinaya Vaisburd et al.   Scientific Reports

ADNP: in search for molecular mechanisms and innovative therapeutic strategies for frontotemporal degeneration

(2015) Illana Gozes et al.   Frontiers in Aging Neuroscience

Activity-dependent neuroprotective protein (ADNP) exhibits striking sexual dichotomy impacting on autistic and Alzheimer’s pathologies

(2015) A Malishkevich et al.   Translational Psychiatry

New horizons in schizophrenia treatment: autophagy protection is coupled with behavioral improvements in a mouse model of schizophrenia

(2014) Avia Merenlender-Wagner et al.   Autophagy

Davunetide in patients with progressive supranuclear palsy: a randomised, double-blind, placebo-controlled phase 2/3 trial

(2014) Adam L Boxer et al.   LANCET NEUROLOGY

The NAP motif of activity-dependent neuroprotective protein (ADNP) regulates dendritic spines through microtubule end binding proteins

(2014) S Oz et al.   MOLECULAR PSYCHIATRY

A SWI/SNF-related autism syndrome caused by de novo mutations in ADNP

(2014) Céline Helsmoortel et al.   NATURE GENETICS

Novel Marker for the Onset of Frontotemporal Dementia: Early Increase in Activity-Dependent Neuroprotective Protein (ADNP) in the Face of Tau Mutation

(2014) Yulie Schirer et al.   PLoS One

The Microtubule-Binding Protein Ensconsin Is an Essential Cofactor of Kinesin-1

(2013) Kari Barlan et al.   CURRENT BIOLOGY

A Double-Blind, Placebo-Controlled, Ascending-Dose, Randomized Study to Evaluate the Safety, Tolerability and Effects on Cognition of AL-108 after 12 Weeks of Intranasal Administration in Subjects with Mild Cognitive Impairment

(2013) Bruce H. Morimoto et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

MAP1B regulates microtubule dynamics by sequestering EB1/3 in the cytosol of developing neuronal cells

(2013) Elena Tortosa et al.   EMBO JOURNAL

Ordered Recruitment of Dynactin to the Microtubule Plus-End is Required for Efficient Initiation of Retrograde Axonal Transport

(2013) A. J. Moughamian et al.   JOURNAL OF NEUROSCIENCE

Autophagy has a key role in the pathophysiology of schizophrenia

(2013) A Merenlender-Wagner et al.   MOLECULAR PSYCHIATRY

NAP (davunetide) rescues neuronal dysfunction in a Drosophila model of tauopathy

(2013) S Quraishe et al.   MOLECULAR PSYCHIATRY

NAP (davunetide) modifies disease progression in a mouse model of severe neurodegeneration: Protection against impairments in axonal transport

(2013) Yan Jouroukhin et al.   NEUROBIOLOGY OF DISEASE

Effects of Davunetide on N-acetylaspartate and Choline in Dorsolateral Prefrontal Cortex in Patients with Schizophrenia

(2013) L Fredrik Jarskog et al.   NEUROPSYCHOPHARMACOLOGY

End Binding Proteins Are Obligatory Dimers

(2013) Indrani Sen et al.   PLoS One

The ADNP Derived Peptide, NAP Modulates the Tubulin Pool: Implication for Neurotrophic and Neuroprotective Activities

(2012) Saar Oz et al.   PLoS One

+TIPs: SxIPping along microtubule ends

(2012) Praveen Kumar et al.   TRENDS IN CELL BIOLOGY

Interaction of mammalian end binding proteins with CAP-Gly domains of CLIP-170 and p150glued

(2011) Saša Bjelić et al.   JOURNAL OF STRUCTURAL BIOLOGY

Fast and robust extraction of hippocampus from MR images for diagnostics of Alzheimer's disease

(2011) Jyrki Lötjönen et al.   NEUROIMAGE

Meta-Analysis for Genome-Wide Association Study Identifies Multiple Variants at the BIN1 Locus Associated with Late-Onset Alzheimer's Disease

(2011) Xiaolan Hu et al.   PLoS One

Effect of the neuroprotective peptide davunetide (AL-108) on cognition and functional capacity in schizophrenia

(2011) Daniel C. Javitt et al.   SCHIZOPHRENIA RESEARCH

Activity-dependent neuroprotective protein (ADNP) expression level is correlated with the expression of the sister protein ADNP2: Deregulation in schizophrenia

(2010) Efrat Dresner et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Strategies for diminishing katanin-based loss of microtubules in tauopathic neurodegenerative diseases

(2010) H. Sudo et al.   HUMAN MOLECULAR GENETICS

Addressing Alzheimers Disease Tangles: From NAP to AL-108

(2009) Illana Gozes et al.   Current Alzheimer Research

Molecular Insights into Mammalian End-binding Protein Heterodimerization

(2009) Christian O. De Groot et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mammalian end binding proteins control persistent microtubule growth

(2009) Yulia Komarova et al.   JOURNAL OF CELL BIOLOGY

NAP protects memory, increases soluble tau and reduces tau hyperphosphorylation in a tauopathy model

(2009) Natalia Shiryaev et al.   NEUROBIOLOGY OF DISEASE

Dynamic Microtubules Regulate Dendritic Spine Morphology and Synaptic Plasticity

(2009) Jacek Jaworski et al.   NEURON

NAP and D-SAL: neuroprotection against the β amyloid peptide (1–42)

(2008) Illana Gozes et al.   BMC NEUROSCIENCE

ADNP Differential Nucleus/Cytoplasm Localization in Neurons Suggests Multiple Roles in Neuronal Differentiation and Maintenance

(2008) Shmuel Mandel et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

A Neuronal Microtubule-Interacting Agent, NAPVSIPQ, Reduces Tau Pathology and Enhances Cognitive Function in a Mouse Model of Alzheimer's Disease

(2008) Y. Matsuoka et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Complete Sequence of a Novel Protein Containing a Femtomolar-Activity-Dependent Neuroprotective Peptide

(2003) Merav Bassan et al.   JOURNAL OF NEUROCHEMISTRY