T cells out of control—impaired immune regulation in the inflamed joint
Published 2012 View Full Article
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Title
T cells out of control—impaired immune regulation in the inflamed joint
Authors
Keywords
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Journal
Nature Reviews Rheumatology
Volume 9, Issue 1, Pages 34-42
Publisher
Springer Nature
Online
2012-09-18
DOI
10.1038/nrrheum.2012.149
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Note: Only part of the references are listed.- Th1, Th2, and Th17 Effector T Cell-Induced Autoimmune Gastritis Differs in Pathological Pattern and in Susceptibility to Suppression by Regulatory T Cells
- (2014) G. H. Stummvoll et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: Expression of TNFR2 Defines a Maximally Suppressive Subset of Mouse CD4+CD25+FoxP3+ T Regulatory Cells: Applicability to Tumor-Infiltrating T Regulatory Cells
- (2014) X. Chen et al. JOURNAL OF IMMUNOLOGY
- Release from Regulatory T Cell-Mediated Suppression during the Onset of Tissue-Specific Autoimmunity Is Associated with Elevated IL-21
- (2014) L. E. Clough et al. JOURNAL OF IMMUNOLOGY
- The Effector T Cells of Diabetic Subjects Are Resistant to Regulation via CD4+FOXP3+ Regulatory T Cells
- (2014) A. Schneider et al. JOURNAL OF IMMUNOLOGY
- Autoimmunity in Dry Eye Is Due to Resistance of Th17 to Treg Suppression
- (2014) S. K. Chauhan et al. JOURNAL OF IMMUNOLOGY
- Th17 Cells
- (2012) Mohan S. Maddur et al. AMERICAN JOURNAL OF PATHOLOGY
- Rarity of Human T Helper 17 Cells Is due to Retinoic Acid Orphan Receptor-Dependent Mechanisms that Limit Their Expansion
- (2012) Veronica Santarlasci et al. IMMUNITY
- Plasticity of Foxp3+ T Cells Reflects Promiscuous Foxp3 Expression in Conventional T Cells but Not Reprogramming of Regulatory T Cells
- (2012) Takahisa Miyao et al. IMMUNITY
- Characterization of Effector Memory CD8+ T Cells in the Synovial Fluid of Rheumatoid Arthritis
- (2012) Bon-A Cho et al. JOURNAL OF CLINICAL IMMUNOLOGY
- CC chemokine receptor 4 is required for experimental autoimmune encephalomyelitis by regulating GM-CSF and IL-23 production in dendritic cells
- (2012) K. Poppensieker et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Impaired suppression of synovial fluid CD4+CD25− T cells from patients with juvenile idiopathic arthritis by CD4+CD25+ Treg cells
- (2011) Susanne Haufe et al. ARTHRITIS AND RHEUMATISM
- Evidence of the transient nature of the Th17 phenotype of CD4+CD161+ T cells in the synovial fluid of patients with juvenile idiopathic arthritis
- (2011) Lorenzo Cosmi et al. ARTHRITIS AND RHEUMATISM
- The response of T cells to interleukin-6 is differentially regulated by the microenvironment of the rheumatoid synovial fluid and tissue
- (2011) Ester Hidalgo et al. ARTHRITIS AND RHEUMATISM
- Anti-TNFα discontinuation in rheumatoid and psoriatic arthritis: Is it possible after disease remission?
- (2011) Maria Sole Chimenti et al. AUTOIMMUNITY REVIEWS
- TH1, TH2, and TH17 cells instruct monocytes to differentiate into specialized dendritic cell subsets
- (2011) M. N. Alonso et al. BLOOD
- Serum amyloid A overrides Treg anergy via monocyte-dependent and Treg-intrinsic, SOCS3-associated pathways
- (2011) K. D. Nguyen et al. BLOOD
- Functional human regulatory T cells fail to control autoimmune inflammation due to PKB/c-akt hyperactivation in effector cells
- (2011) E. J. Wehrens et al. BLOOD
- The inflammatory milieu in the rheumatic joint reduces regulatory T-cell function
- (2011) Jessica Herrath et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- CD4+CD25+Foxp3+ Regulatory T Cells Promote Th17 Cells In Vitro and Enhance Host Resistance in Mouse Candida albicans Th17 Cell Infection Model
- (2011) Pushpa Pandiyan et al. IMMUNITY
- Foxp3+ Regulatory T Cells Promote T Helper 17 Cell Development In Vivo through Regulation of Interleukin-2
- (2011) Yi Chen et al. IMMUNITY
- FAS/FAS-L dependent killing of activated human monocytes and macrophages by CD4+CD25− responder T cells, but not CD4+CD25+ regulatory T cells
- (2011) Ann L. Jagger et al. JOURNAL OF AUTOIMMUNITY
- TRAIL Is Associated with Impaired Regulation of CD4+CD25− T Cells by Regulatory T Cells in Patients with Rheumatoid Arthritis
- (2011) Hong Xiao et al. JOURNAL OF CLINICAL IMMUNOLOGY
- Differentiation of Inflammatory Dendritic Cells Is Mediated by NF- B1-Dependent GM-CSF Production in CD4 T Cells
- (2011) I. K. Campbell et al. JOURNAL OF IMMUNOLOGY
- Plasticity of Human Regulatory T Cells in Healthy Subjects and Patients with Type 1 Diabetes
- (2011) Stephanie A. McClymont et al. JOURNAL OF IMMUNOLOGY
- Single-Cell Analysis of the Human T Regulatory Population Uncovers Functional Heterogeneity and Instability within FOXP3+ Cells
- (2011) E. d'Hennezel et al. JOURNAL OF IMMUNOLOGY
- Identification of T helper type 1–like, Foxp3+ regulatory T cells in human autoimmune disease
- (2011) Margarita Dominguez-Villar et al. NATURE MEDICINE
- Biologic predictors of extension of oligoarticular juvenile idiopathic arthritis as determined from synovial fluid cellular composition and gene expression
- (2010) Patricia J. Hunter et al. ARTHRITIS AND RHEUMATISM
- Co-expression of TNFR2 and CD25 identifies more of the functional CD4+FOXP3+regulatory T cells in human peripheral blood
- (2010) Xin Chen et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Pathogenic T cells have a paradoxical protective effect in murine autoimmune diabetes by boosting Tregs
- (2010) Yenkel Grinberg-Bleyer et al. JOURNAL OF CLINICAL INVESTIGATION
- TNF Activates a NF- B-Regulated Cellular Program in Human CD45RA- Regulatory T Cells that Modulates Their Suppressive Function
- (2010) M. Nagar et al. JOURNAL OF IMMUNOLOGY
- Profiling of CD4+ T Cells with Epigenetic Immune Lineage Analysis
- (2010) P. C. J. Janson et al. JOURNAL OF IMMUNOLOGY
- The yin and yang of regulatory T cells and inflammation in RA
- (2010) Clare A. Notley et al. Nature Reviews Rheumatology
- Th17 plasticity in human autoimmune arthritis is driven by the inflammatory environment
- (2010) K. Nistala et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Surveillance of Antigen-Presenting Cells by CD4+CD25+ Regulatory T Cells in Autoimmunity
- (2009) Sébastien André et al. AMERICAN JOURNAL OF PATHOLOGY
- IL-17-producing human peripheral regulatory T cells retain suppressive function
- (2009) G. Beriou et al. BLOOD
- Mechanisms of Foxp3+ T Regulatory Cell-Mediated Suppression
- (2009) Ethan M. Shevach IMMUNITY
- Late Developmental Plasticity in the T Helper 17 Lineage
- (2009) Yun Kyung Lee et al. IMMUNITY
- Highly purified Th17 cells from BDC2.5NOD mice convert into Th1-like cells in NOD/SCID recipient mice
- (2009) David Bending et al. JOURNAL OF CLINICAL INVESTIGATION
- Cutting Edge: Responder T Cells Regulate Human DR+ Effector Regulatory T Cell Activity via Granzyme B
- (2009) C. W. Ashley et al. JOURNAL OF IMMUNOLOGY
- IL-17 Induces Monocyte Migration in Rheumatoid Arthritis
- (2009) S. Shahrara et al. JOURNAL OF IMMUNOLOGY
- Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo
- (2009) Xuyu Zhou et al. NATURE IMMUNOLOGY
- Regulatory T cells as therapeutic targets in rheumatoid arthritis
- (2009) Jonathan H. Esensten et al. Nature Reviews Rheumatology
- IL-17 as a future therapeutic target for rheumatoid arthritis
- (2009) Wim B. van den Berg et al. Nature Reviews Rheumatology
- In vivo activated monocytes from the site of inflammation in humans specifically promote Th17 responses
- (2009) H. G. Evans et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Heterogeneity of natural Foxp3+T cells: A committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity
- (2009) Noriko Komatsu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dysfunctional CD4+,CD25+ regulatory T cells in untreated active systemic lupus erythematosus secondary to interferon-α–producing antigen-presenting cells
- (2008) Bing Yan et al. ARTHRITIS AND RHEUMATISM
- Function of CD4+,CD25+ Treg cells in MRL/lpr mice is compromised by intrinsic defects in antigen-presenting cells and effector T cells
- (2008) Véronique Parietti et al. ARTHRITIS AND RHEUMATISM
- Interleukin-17–producing T cells are enriched in the joints of children with arthritis, but have a reciprocal relationship to regulatory T cell numbers
- (2008) Kiran Nistala et al. ARTHRITIS AND RHEUMATISM
- Reduced CD4+,CD25− T cell sensitivity to the suppressive function of CD4+,CD25high,CD127−/lowregulatory T cells in patients with active systemic lupus erythematosus
- (2008) Ram Kumar Chowdary Venigalla et al. ARTHRITIS AND RHEUMATISM
- Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells
- (2008) H. J. P. M. Koenen et al. BLOOD
- Increased resistance to CD4+CD25hiregulatory T cell-mediated suppression in patients with type 1 diabetes
- (2008) J. M. Lawson et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Molecular Antagonism and Plasticity of Regulatory and Inflammatory T Cell Programs
- (2008) Xuexian O. Yang et al. IMMUNITY
- Quantitative and qualitative normal regulatory T cells are not capable of inducing suppression in SLE patients due to T-cell resistance
- (2008) MI Vargas-Rojas et al. LUPUS
- IL-21 and TGF-β are required for differentiation of human TH17 cells
- (2008) Li Yang et al. NATURE
- A critical function for transforming growth factor-β, interleukin 23 and proinflammatory cytokines in driving and modulating human TH-17 responses
- (2008) Elisabetta Volpe et al. NATURE IMMUNOLOGY
- The differentiation of human TH-17 cells requires transforming growth factor-β and induction of the nuclear receptor RORγt
- (2008) Nicolas Manel et al. NATURE IMMUNOLOGY
- Defects in CTLA-4 are associated with abnormal regulatory T cell function in rheumatoid arthritis
- (2008) F. Flores-Borja et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The defect in T-cell regulation in NOD mice is an effect on the T-cell effectors
- (2008) A. M. D'Alise et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Distribution and clinical significance of blood dendritic cells in children with juvenile idiopathic arthritis
- (2007) E Smolewska et al. ANNALS OF THE RHEUMATIC DISEASES
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