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Cutting Edge: The Pathogenicity of IFN- -Producing Th17 Cells Is Independent of T-bet

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Effect of IL-17A blockade with secukinumab in autoimmune diseases

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Identification of early gene expression changes during human Th17 cell differentiation

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Autoimmunity in 2011

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Emerging new roles of Th17 cells

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Coexpression of CCR6 and CD146 (MCAM) is a marker of effector memory T-helper 17 cells

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Human Th17 Cells Express High Levels of Enzymatically Active Dipeptidylpeptidase IV (CD26)

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IL-23 induces spondyloarthropathy by acting on ROR-γt+ CD3+CD4−CD8− entheseal resident T cells

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Targeting IL-17 and TH17 cells in chronic inflammation

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Laminin-411 Is a Vascular Ligand for MCAM and Facilitates TH17 Cell Entry into the CNS

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The link between HLA-B27 and SpA--new ideas on an old problem

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New insights into the genetics of immune responses in rheumatoid arthritis

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Defining the human T helper 17 cell phenotype

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CD4 T cells and their antigens in the pathogenesis of autoimmune diabetes

(2011) Kathryn Haskins et al.   CURRENT OPINION IN IMMUNOLOGY

Recent advances in IL-22 biology

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MCAM-expressing CD4+ T cells in peripheral blood secrete IL-17A and are significantly elevated in inflammatory autoimmune diseases

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Fate mapping of IL-17-producing T cells in inflammatory responses

(2011) Keiji Hirota et al.   NATURE IMMUNOLOGY

2010 Rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative

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Synovial fluid-derived T helper 17 cells correlate with inflammatory activity in arthritis, irrespectively of diagnosis

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Epidemiology of Ankylosing Spondylitis: IGAS 2009

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Frequency and Phenotype of T Helper 17 Cells in Peripheral Blood and Synovial Fluid of Patients with Reactive Arthritis

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Generation of pathogenic TH17 cells in the absence of TGF-β signalling

(2010) Kamran Ghoreschi et al.   NATURE

Frequency and phenotype of peripheral blood Th17 cells in ankylosing spondylitis and rheumatoid arthritis

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Phenotypical and functional characterization of T helper 17 cells in multiple sclerosis

(2009) Verena Brucklacher-Waldert et al.   BRAIN

Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation

(2009) Melanie A. Kleinschek et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Increased numbers of circulating polyfunctional Th17 memory cells in patients with seronegative spondylarthritides

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IL-21 and TGF-β are required for differentiation of human TH17 cells

(2008) Li Yang et al.   NATURE