Polysulfide and Hydrogen Sulfide Ameliorate Cisplatin-Induced Nephrotoxicity and Renal Inflammation through Persulfidating STAT3 and IKKβ

Protective Smell of Hydrogen Sulfide and Polysulfide in Cisplatin-Induced Nephrotoxicity

(2019) Xu Cao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Immunomodulatory Effects of Glutathione, Garlic Derivatives, and Hydrogen Sulfide

(2019) Camila Rodrigues et al.   Nutrients

Renoprotective effect of scutellarin on cisplatin-induced renal injury in mice: Impact on inflammation, apoptosis, and autophagy

(2019) Chao-Yue Sun et al.   BIOMEDICINE & PHARMACOTHERAPY

Tetramethylpyrazine guards against cisplatin-induced nephrotoxicity in rats through inhibiting HMGB1/TLR4/NF-κB and activating Nrf2 and PPAR-γ signaling pathways

(2019) Haidy E. Michel et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Rethinking Alkylating(-Like) Agents for Solid Tumor Management

(2019) Hélène Lajous et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

S-Sulfhydration of SIRT3 by Hydrogen Sulfide Attenuates Mitochondrial Dysfunction in Cisplatin-Induced Acute Kidney Injury

(2019) Yujia Yuan et al.   ANTIOXIDANTS & REDOX SIGNALING

Recent Advances in Models, Mechanisms, Biomarkers, and Interventions in Cisplatin-Induced Acute Kidney Injury

(2019) Sara J. Holditch et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Hydrogen Sulfide Prevents Elastin Loss and Attenuates Calcification Induced by High Glucose in Smooth Muscle Cells through Suppression of Stat3/Cathepsin S Signaling Pathway

(2019) Ye-Bo Zhou et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Endogenous hydrogen sulfide sulfhydrates IKKβ at cysteine 179 to control pulmonary artery endothelial cell inflammation

(2019) Da Zhang et al.   CLINICAL SCIENCE

H2S alleviates renal injury and fibrosis in response to unilateral ureteral obstruction by regulating macrophage infiltration via inhibition of NLRP3 signaling

(2019) Yueyuan Zhou et al.   EXPERIMENTAL CELL RESEARCH

Impact of garlic (Allium sativum) oil on cisplatin-induced hepatorenal biochemical and histopathological alterations in rats

(2019) Mohamed M. Abdel-Daim et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Salusin-β mediates tubular cell apoptosis in acute kidney injury: Involvement of the PKC/ROS signaling pathway

(2019) Qing-Bo Lu et al.   Redox Biology

Renal Protective Effect of Hydrogen Sulfide in Cisplatin-Induced Nephrotoxicity

(2018) Xu Cao et al.   ANTIOXIDANTS & REDOX SIGNALING

Hydrogen sulfide inhibits ATP-induced neuroinflammation and Aβ 1–42 synthesis by suppressing the activation of STAT3 and cathepsin S

(2018) Lei Cao et al.   BRAIN BEHAVIOR AND IMMUNITY

Garlic and Gaseous Mediators

(2018) Peter Rose et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Renal protective effect of polysulfide in cisplatin-induced nephrotoxicity

(2018) Xu Cao et al.   Redox Biology

Celastrol ameliorates cisplatin nephrotoxicity by inhibiting NF-κB and improving mitochondrial function

(2018) Xiaowen Yu et al.   EBioMedicine

Phytochemicals: Current strategy to sensitize cancer cells to cisplatin

(2018) Chao-Yue Sun et al.   BIOMEDICINE & PHARMACOTHERAPY

Total Coumarins from Hydrangea paniculata Protect against Cisplatin-Induced Acute Kidney Damage in Mice by Suppressing Renal Inflammation and Apoptosis

(2017) Zhang Sen et al.   Evidence-based Complementary and Alternative Medicine

Boiling enriches the linear polysulfides and the hydrogen sulfide-releasing activity of garlic

(2017) Restituto Tocmo et al.   FOOD CHEMISTRY

Diallyl trisulfide, a garlic polysulfide protects against As-induced renal oxidative nephrotoxicity, apoptosis and inflammation in rats by activating the Nrf2/ARE signaling pathway

(2017) S. Miltonprabu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

C1q/TNF-Related Protein-9 Ameliorates Ox-LDL-Induced Endothelial Dysfunction via PGC-1α/AMPK-Mediated Antioxidant Enzyme Induction

(2017) Haijian Sun et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cisplatin nephrotoxicity: a review of the literature

(2017) Sandhya Manohar et al.   JOURNAL OF NEPHROLOGY

Hydrogen sulfide ameliorates chronic renal failure in rats by inhibiting apoptosis and inflammation through ROS/MAPK and NF-κB signaling pathways

(2017) Dongdong Wu et al.   Scientific Reports

Garlic-derived natural polysulfanes as hydrogen sulfide donors: Friend or foe?

(2016) Esma Yagdi et al.   FOOD AND CHEMICAL TOXICOLOGY

GYY4137, a Slow-Releasing Hydrogen Sulfide Donor, Ameliorates Renal Damage Associated with Chronic Obstructive Uropathy

(2016) Shouzhe Lin et al.   JOURNAL OF UROLOGY

A H2S Donor GYY4137 Exacerbates Cisplatin-Induced Nephrotoxicity in Mice

(2016) Mi Liu et al.   MEDIATORS OF INFLAMMATION

Hydrogen sulfide: A novel nephroprotectant against cisplatin-induced renal toxicity

(2016) George J. Dugbartey et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Plant-Derived Agents for Counteracting Cisplatin-Induced Nephrotoxicity

(2016) Shreesh Ojha et al.   Oxidative Medicine and Cellular Longevity

Saikosaponin-D reduces cisplatin-induced nephrotoxicity by repressing ROS-mediated activation of MAPK and NF-κB signalling pathways

(2015) Xiaobin Ma et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Hydrogen Sulfide Donor GYY4137 Protects against Myocardial Fibrosis

(2015) Guoliang Meng et al.   Oxidative Medicine and Cellular Longevity

Hydrogen sulfide in pharmacology and medicine – An update

(2015) Jerzy Bełtowski   Pharmacological Reports

Antimetastatic Therapies of the Polysulfide Diallyl Trisulfide against Triple-Negative Breast Cancer (TNBC) via Suppressing MMP2/9 by Blocking NF-κB and ERK/MAPK Signaling Pathways

(2015) Yuping Liu et al.   PLoS One

Cancer Cell Growth Is Differentially Affected by Constitutive Activation of NRF2 by KEAP1 Deletion and Pharmacological Activation of NRF2 by the Synthetic Triterpenoid, RTA 405

(2015) Brandon L. Probst et al.   PLoS One

Hydrogen Sulfide Alleviates Diabetic Nephropathy in a Streptozotocin-induced Diabetic Rat Model

(2014) Xiang Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hydrogen sulfide and the liver

(2014) Sarathi Mani et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Protective effect of hydrogen sulfide on gentamicin-induced renal injury

(2014) Alper Otunctemur et al.   RENAL FAILURE

Pathophysiology of Cisplatin-Induced Acute Kidney Injury

(2014) Abdullah Ozkok et al.   Biomed Research International

STAT3 Regulation by S-Nitrosylation: Implication for Inflammatory Disease

(2013) Jinsu Kim et al.   ANTIOXIDANTS & REDOX SIGNALING

Involvement of hydrogen sulfide and homocysteine transsulfuration pathway in the progression of kidney fibrosis after ureteral obstruction

(2013) Kyong-Jin Jung et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Signalling mechanisms involved in renal pathological changes during cisplatin-induced nephropathy

(2013) Siddesh Jaiman et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Pharmacological activation of NQO1 increases NAD+ levels and attenuates cisplatin-mediated acute kidney injury in mice

(2013) Gi-Su Oh et al.   KIDNEY INTERNATIONAL

Hydrogen sulfide inhibits the renal fibrosis of obstructive nephropathy

(2013) Kai Song et al.   KIDNEY INTERNATIONAL

Regulation of NF-κB by ubiquitination and degradation of the IκBs

(2012) Naama Kanarek et al.   IMMUNOLOGICAL REVIEWS

The noncanonical NF-κB pathway

(2012) Shao-Cong Sun   IMMUNOLOGICAL REVIEWS

Cytoprotective actions of hydrogen sulfide in ischaemia-reperfusion injury

(2011) Adrienne L. King et al.   EXPERIMENTAL PHYSIOLOGY

Rescue of mesangial cells from high glucose-induced over-proliferation and extracellular matrix secretion by hydrogen sulfide

(2011) P. Yuan et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Cisplatin as an Anti-Tumor Drug: Cellular Mechanisms of Activity, Drug Resistance and Induced Side Effects

(2011) Ana-Maria Florea et al.   Cancers

NF-κB and STAT3 – key players in liver inflammation and cancer

(2010) Guobin He et al.   CELL RESEARCH

NF-κB Signaling: Multiple Angles to Target OA

(2010) Kenneth B. Marcu et al.   CURRENT DRUG TARGETS

Inhibition of hydrogen sulphide formation reduces cisplatin-induced renal damage

(2010) H. D. C. Francescato et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Mechanisms of Cisplatin Nephrotoxicity

(2010) Ronald P. Miller et al.   Toxins

Characterisation of cystathionine gamma-lyase/hydrogen sulphide pathway in ischaemia/reperfusion injury of the mouse kidney: An in vivo study

(2009) Pinpat Tripatara et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Characterization of a Novel, Water-Soluble Hydrogen Sulfide–Releasing Molecule (GYY4137)

(2008) Ling Li et al.   CIRCULATION

Garlic Powder Ameliorates Cisplatin-Induced Nephrotoxicity and Oxidative Stress

(2008) Ana Carolina Razo-Rodríguez et al.   JOURNAL OF MEDICINAL FOOD

Cisplatin nephrotoxicity: Mechanisms and renoprotective strategies

(2008) N. Pabla et al.   KIDNEY INTERNATIONAL

Generation of endogenous hydrogen sulfide by cystathionine γ-lyase limits renal ischemia/reperfusion injury and dysfunction

(2008) Pinpat Tripatara et al.   LABORATORY INVESTIGATION