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Title
Prolyl and lysyl hydroxylases in collagen synthesis
Authors
Keywords
-
Journal
EXPERIMENTAL DERMATOLOGY
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2020-09-24
DOI
10.1111/exd.14197
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Note: Only part of the references are listed.- An Oxygen Sensation: Progress in Macromolecule Hydroxylation Triggered by the Elucidation of Cellular Oxygen Sensing
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- (2019) Steve Stegen et al. NATURE
- SiMPLOD, a structure‐integrated database of collagen lysyl hydroxylase (LH/PLOD) enzyme variants
- (2019) Luigi Scietti et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Deficiency of lysyl hydroxylase 2 in mice causes systemic endoplasmic reticulum stress leading to early embryonic lethality
- (2019) Atsushi Kasamatsu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- A structural prospective for collagen receptors such as DDR and their binding of the collagen fibril
- (2019) Joseph P.R.O. Orgel et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Loss of function of Colgalt1 disrupts collagen post-translational modification and causes musculoskeletal defects
- (2019) Krista A. Geister et al. Disease Models & Mechanisms
- Pathogenic variants in PLOD3 result in a Stickler syndrome-like connective tissue disorder with vascular complications
- (2019) Lisa Jean Ewans et al. JOURNAL OF MEDICAL GENETICS
- Collagen glycosylation
- (2019) Thierry Hennet CURRENT OPINION IN STRUCTURAL BIOLOGY
- Roles of the procollagen C-propeptides in health and disease
- (2019) David J.S. Hulmes Essays in Biochemistry
- Collagen cross-linking mediated by lysyl hydroxylase 2: an enzymatic battlefield to combat fibrosis
- (2019) Bram Piersma et al. Essays in Biochemistry
- Role of prolyl hydroxylation in the molecular interactions of collagens
- (2019) Pekka Rappu et al. Essays in Biochemistry
- Cyclophilin B control of lysine post-translational modifications of skin type I collagen
- (2019) Masahiko Terajima et al. PLoS Genetics
- Hypoxia-Inducible Factor Activators in Renal Anemia: Current Clinical Experience
- (2019) Neil S. Sanghani et al. ADVANCES IN CHRONIC KIDNEY DISEASE
- Lysyl oxidases: from enzyme activity to extracellular matrix cross-links
- (2019) Sylvain D. Vallet et al. Essays in Biochemistry
- Mechanisms of hypoxia signalling: new implications for nephrology
- (2019) Johannes Schödel et al. Nature Reviews Nephrology
- Exploring the roles of MACIT and multiplexin collagens in stem cells and cancer
- (2019) Valerio Izzi et al. SEMINARS IN CANCER BIOLOGY
- Role of Glycosyltransferase 25 Domain 1 in Type I Collagen Glycosylation and Molecular Phenotypes
- (2019) Masahiko Terajima et al. BIOCHEMISTRY
- 2-Oxoglutarate-Dependent Oxygenases
- (2018) Md. Saiful Islam et al. Annual Review of Biochemistry
- Autosomal-dominant myopia associated to a novel P4HA2 missense variant and defective collagen hydroxylation
- (2018) F. Napolitano et al. CLINICAL GENETICS
- Post-translational modification of type IV collagen with 3-hydroxyproline affects its interactions with glycoprotein VI and nidogens 1 and 2
- (2018) Nathan T. Montgomery et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Proline hydroxylation in collagen supports integrin binding by two distinct mechanisms
- (2018) Kalle H. Sipilä et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Molecular Basis of Genetic Collagen Disorders and Its Clinical Relevance
- (2018) Antonia Chen et al. JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
- The triple helix of collagens – an ancient protein structure that enabled animal multicellularity and tissue evolution
- (2018) Aaron L. Fidler et al. JOURNAL OF CELL SCIENCE
- Collagen Prolyl 4-Hydroxylase as a Therapeutic Target
- (2018) James D. Vasta et al. JOURNAL OF MEDICINAL CHEMISTRY
- Hypoxic Signalling in Tumour Stroma
- (2018) Anu Laitala et al. Frontiers in Oncology
- Autozygome and high throughput confirmation of disease genes candidacy
- (2018) Sateesh Maddirevula et al. GENETICS IN MEDICINE
- Structural enzymology binding studies of the peptide-substrate-binding domain of human collagen prolyl 4-hydroxylase (type-II): high affinity peptides have a PxGP sequence motif
- (2018) Abhinandan V. Murthy et al. PROTEIN SCIENCE
- Matrix molecules and skin biology
- (2018) Alexander Nyström et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Molecular architecture of the multifunctional collagen lysyl hydroxylase and glycosyltransferase LH3
- (2018) Luigi Scietti et al. Nature Communications
- Biallelic COLGALT1 variants are associated with cerebral small vessel disease
- (2018) Satoko Miyatake et al. ANNALS OF NEUROLOGY
- Mutations in PLOD3, encoding lysyl hydroxylase 3, cause a complex connective tissue disorder including recessive dystrophic epidermolysis bullosa-like blistering phenotype with abnormal anchoring fibrils and type VII collagen deficiency
- (2018) Hassan Vahidnezhad et al. MATRIX BIOLOGY
- Fishing for collagen function: About development, regeneration and disease
- (2018) Sandrine Bretaud et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- A cohort of 17 patients with kyphoscoliotic Ehlers–Danlos syndrome caused by biallelic mutations in FKBP14: expansion of the clinical and mutational spectrum and description of the natural history
- (2017) Cecilia Giunta et al. GENETICS IN MEDICINE
- P4HA1 mutations cause a unique congenital disorder of connective tissue involving tendon, bone, muscle and the eye
- (2017) Yaqun Zou et al. HUMAN MOLECULAR GENETICS
- Heat shock protein 47 and 65-kDa FK506-binding protein weakly but synergistically interact during collagen folding in the endoplasmic reticulum
- (2017) Yoshihiro Ishikawa et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- P3h3-null and Sc65-null Mice Phenocopy the Collagen Lysine Under-hydroxylation and Cross-linking Abnormality of Ehlers-Danlos Syndrome Type VIA
- (2017) David M. Hudson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2017) Caressa D Lietman et al. JOURNAL OF BONE AND MINERAL RESEARCH
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- (2017) Ivan Duran et al. JOURNAL OF BONE AND MINERAL RESEARCH
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- (2017) Meena Balasubramanian et al. JOURNAL OF MEDICAL GENETICS
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- (2017) Lixue Ouyang et al. MEDICINE
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- (2015) Trayambak Basak et al. JOURNAL OF PROTEOME RESEARCH
- Osteogenesis imperfecta due to mutations in non-collagenous genes
- (2014) Joan C. Marini et al. CURRENT OPINION IN PEDIATRICS
- Lysine post-translational modifications of collagen
- (2014) Mitsuo Yamauchi et al. Essays in Biochemistry
- Connective tissue alterations in Fkbp10−/− mice
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- (2014) Arif O. Khan et al. OPHTHALMIC GENETICS
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- (2014) David M. Hudson et al. PLoS One
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- (2013) Daniele M. Gilkes et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Sc65 Is a Novel Endoplasmic Reticulum Protein That Regulates Bone Mass Homeostasis
- (2013) Katrin Gruenwald et al. JOURNAL OF BONE AND MINERAL RESEARCH
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- (2011) Sergei P. Boudko et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
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- (2011) David R. Eyre et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2010) Brian P Kelley et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Dimerization of human lysyl hydroxylase 3 (LH3) is mediated by the amino acids 541–547
- (2010) Jari Heikkinen et al. MATRIX BIOLOGY
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- (2010) Dustin Baldridge et al. PLoS One
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- (2010) S. Ricard-Blum Cold Spring Harbor Perspectives in Biology
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- (2009) Matthew D. Shoulders et al. Annual Review of Biochemistry
- Extracellular matrix genes as hypoxia-inducible targets
- (2009) Johanna Myllyharju et al. CELL AND TISSUE RESEARCH
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- (2009) Janice Vranka et al. CELL STRUCTURE AND FUNCTION
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- (2009) Weizhong Chang et al. HUMAN MOLECULAR GENETICS
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- (2009) Yoshihiro Ishikawa et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2009) Marjo Hyry et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2009) M. Kristian Koski et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Location of 3-Hydroxyproline Residues in Collagen Types I, II, III, and V/XI Implies a Role in Fibril Supramolecular Assembly
- (2009) Mary Ann Weis et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structural Basis for Binding of Hypoxia-Inducible Factor to the Oxygen-Sensing Prolyl Hydroxylases
- (2009) Rasheduzzaman Chowdhury et al. STRUCTURE
- Severe Osteogenesis Imperfecta in Cyclophilin B–Deficient Mice
- (2009) Jae Won Choi et al. PLoS Genetics
- A Connective Tissue Disorder Caused by Mutations of the Lysyl Hydroxylase 3 Gene
- (2008) Antti M. Salo et al. AMERICAN JOURNAL OF HUMAN GENETICS
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- (2008) Johanna Myllyharju ANNALS OF MEDICINE
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- (2008) Päivi Tiainen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Core Glycosylation of Collagen Is Initiated by Two (1-O)Galactosyltransferases
- (2008) B. Schegg et al. MOLECULAR AND CELLULAR BIOLOGY
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