Role of prolyl hydroxylation in the molecular interactions of collagens

HIF-1α metabolically controls collagen synthesis and modification in chondrocytes

(2019) Steve Stegen et al.   NATURE

A structural prospective for collagen receptors such as DDR and their binding of the collagen fibril

(2019) Joseph P.R.O. Orgel et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Proline hydroxylation in collagen supports integrin binding by two distinct mechanisms

(2018) Kalle H. Sipilä et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural enzymology binding studies of the peptide-substrate-binding domain of human collagen prolyl 4-hydroxylase (type-II): high affinity peptides have a PxGP sequence motif

(2018) Abhinandan V. Murthy et al.   PROTEIN SCIENCE

Proline provides site-specific flexibility for in vivo collagen

(2018) Wing Ying Chow et al.   Scientific Reports

Cryptic binding sites become accessible through surface reconstruction of the type I collagen fibril

(2018) Jie Zhu et al.   Scientific Reports

P4HA1 mutations cause a unique congenital disorder of connective tissue involving tendon, bone, muscle and the eye

(2017) Yaqun Zou et al.   HUMAN MOLECULAR GENETICS

P3h3-null and Sc65-null Mice Phenocopy the Collagen Lysine Under-hydroxylation and Cross-linking Abnormality of Ehlers-Danlos Syndrome Type VIA

(2017) David M. Hudson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

P4HBrecurrent missense mutation causing Cole-Carpenter syndrome

(2017) Meena Balasubramanian et al.   JOURNAL OF MEDICAL GENETICS

The binding capacity of α1β1-, α2β1- and α10β1-integrins depends on non-collagenous surface macromolecules rather than the collagens in cartilage fibrils

(2017) Christian Woltersdorf et al.   MATRIX BIOLOGY

Role of Integrins α1β1 and α2β1 in Wound and Tumor Angiogenesis in Mice

(2016) Sushmita Ghatak et al.   AMERICAN JOURNAL OF PATHOLOGY

Collagen structure: new tricks from a very old dog

(2016) J. Bella   BIOCHEMICAL JOURNAL

The integrin–collagen connection – a glue for tissue repair?

(2016) Cédric Zeltz et al.   JOURNAL OF CELL SCIENCE

Cole-Carpenter Syndrome Is Caused by a Heterozygous Missense Mutation in P4HB

(2015) Frank Rauch et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Mutations of P4HA2 encoding prolyl 4-hydroxylase 2 are associated with nonsyndromic high myopia

(2015) Hui Guo et al.   GENETICS IN MEDICINE

Post-translationally Abnormal Collagens of Prolyl 3-Hydroxylase-2 Null Mice Offer a Pathobiological Mechanism for the High Myopia Linked to HumanLEPREL1Mutations

(2015) David M. Hudson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Recombinant Collagen Engineered to Bind to Discoidin Domain Receptor Functions as a Receptor Inhibitor

(2015) Bo An et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Severe Extracellular Matrix Abnormalities and Chondrodysplasia in Mice Lacking Collagen Prolyl 4-Hydroxylase Isoenzyme II in Combination with a Reduced Amount of Isoenzyme I

(2015) Ellinoora Aro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Developmental Stage-dependent Regulation of Prolyl 3-Hydroxylation in Tendon Type I Collagen

(2015) Yuki Taga et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reduced Granulation Tissue and Wound Strength in the Absence of α11β1 Integrin

(2015) Jan-Niklas Schulz et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Collagen XXII binds to collagen-binding integrins via the novel motifs GLQGER and GFKGER

(2014) Daniela Zwolanek et al.   BIOCHEMICAL JOURNAL

Collagen Prolyl Hydroxylases Are Essential for Breast Cancer Metastasis

(2013) D. M. Gilkes et al.   CANCER RESEARCH

A discoidin domain receptor 1 knock-out mouse as a novel model for osteoarthritis of the temporomandibular joint

(2013) Boris Schminke et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Effects of Vitamin C on health: a review of evidence

(2013) Roberto Bei   Frontiers in Bioscience-Landmark

The Structure of Integrin α1I Domain in Complex with a Collagen-mimetic Peptide

(2013) Yanni K.-Y. Chin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Canine Chondrodysplasia Caused by a Truncating Mutation in Collagen-Binding Integrin Alpha Subunit 10

(2013) Kaisa Kyöstilä et al.   PLoS One

Distinct biophysical mechanisms of focal adhesion kinase mechanoactivation by different extracellular matrix proteins

(2013) J. Seong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypoxia-inducible Factor-1 (HIF-1) but Not HIF-2 Is Essential for Hypoxic Induction of Collagen Prolyl 4-Hydroxylases in Primary Newborn Mouse Epiphyseal Growth Plate Chondrocytes

(2012) Ellinoora Aro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mapping of Potent and Specific Binding Motifs, GLOGEN and GVOGEA, for Integrin α1β1 Using Collagen Toolkits II and III

(2012) Samir W. Hamaia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Constitutive Dimerization of Glycoprotein VI (GPVI) in Resting Platelets Is Essential for Binding to Collagen and Activation in Flowing Blood

(2012) Stephanie M. Jung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High Myopia Caused by a Mutation in LEPREL1, Encoding Prolyl 3-Hydroxylase 2

(2011) Shikma Mordechai et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A Novel 3-Hydroxyproline (3Hyp)-rich Motif Marks the Triple-helical C Terminus of Tendon Type I Collagen

(2011) David R. Eyre et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dwarfism in Mice Lacking Collagen-binding Integrins α2β1 and α11β1 Is Caused by Severely Diminished IGF-1 Levels

(2011) Katrin Blumbach et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prolyl 4-hydroxylase

(2010) Kelly L. Gorres et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

An Engineered α1 Integrin-binding Collagenous Sequence

(2010) Neungseon Seo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prolyl 3-Hydroxylase 1 Null Mice Display Abnormalities in Fibrillar Collagen-rich Tissues Such as Tendons, Skin, and Bones

(2010) Janice A. Vranka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Collagen binding specificity of the discoidin domain receptors: Binding sites on collagens II and III and molecular determinants for collagen IV recognition by DDR1

(2010) Huifang Xu et al.   MATRIX BIOLOGY

Extracellular matrix genes as hypoxia-inducible targets

(2009) Johanna Myllyharju et al.   CELL AND TISSUE RESEARCH

Cellular Receptors of Extracellular Matrix Molecules

(2009) Jyrki Heino et al.   CURRENT PHARMACEUTICAL DESIGN

Location of 3-Hydroxyproline Residues in Collagen Types I, II, III, and V/XI Implies a Role in Fibril Supramolecular Assembly

(2009) Mary Ann Weis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mapping proteolytic cancer cell-extracellular matrix interfaces

(2008) Katarina Wolf et al.   CLINICAL & EXPERIMENTAL METASTASIS

Effect of the -Gly-3(S)-hydroxyprolyl-4(R)-hydroxyprolyl- tripeptide unit on the stability of collagen model peptides

(2008) Kazunori Mizuno et al.   FEBS Journal

Characterization of Recombinant Human Prolyl 3-Hydroxylase Isoenzyme 2, an Enzyme Modifying the Basement Membrane Collagen IV

(2008) Päivi Tiainen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of High Affinity Binding Motifs for the Discoidin Domain Receptor DDR2 in Collagen

(2008) Antonios D. Konitsiotis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Candidate Cell and Matrix Interaction Domains on the Collagen Fibril, the Predominant Protein of Vertebrates

(2008) Shawn M. Sweeney et al.   JOURNAL OF BIOLOGICAL CHEMISTRY