Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics

Single-Cell Transcriptome Atlas of Murine Endothelial Cells

(2020) Joanna Kalucka et al.   CELL

Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage

(2019) Dvir Aran et al.   NATURE IMMUNOLOGY

CD39 identifies a microenvironment-specific anti-inflammatory CD8+ T-cell population in atherosclerotic lesions

(2019) Janine van Duijn et al.   ATHEROSCLEROSIS

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Lipid-Associated Macrophages Control Metabolic Homeostasis in a Trem2-Dependent Manner

(2019) Diego Adhemar Jaitin et al.   CELL

Increased lymphocyte activation and atherosclerosis in CD47-deficient mice

(2019) Daniel Engelbertsen et al.   Scientific Reports

Salmonella Pathogenicity Island 1 (SPI-1) and Its Complex Regulatory Network

(2019) Lixin Lou et al.   Frontiers in Cellular and Infection Microbiology

Single-cell immune landscape of human atherosclerotic plaques

(2019) Dawn M. Fernandez et al.   NATURE MEDICINE

Single-Cell RNA-Seq Reveals the Transcriptional Landscape and Heterogeneity of Aortic Macrophages in Murine AtherosclerosisNovelty and Significance

(2018) Clément Cochain et al.   CIRCULATION RESEARCH

Atlas of the Immune Cell Repertoire in Mouse Atherosclerosis Defined by Single-Cell RNA-Sequencing and Mass CytometryNovelty and Significance

(2018) Holger Winkels et al.   CIRCULATION RESEARCH

Human dendritic cell subsets: an update

(2018) Matthew Collin et al.   IMMUNOLOGY

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

Global characterization of T cells in non-small-cell lung cancer by single-cell sequencing

(2018) Xinyi Guo et al.   NATURE MEDICINE

The morphological and molecular mechanisms of epithelial/endothelial-to-mesenchymal transition and its involvement in atherosclerosis

(2018) M. Wesseling et al.   VASCULAR PHARMACOLOGY

Endothelial to Mesenchymal Transition Represents a Key Link in the Interaction between Inflammation and Endothelial Dysfunction

(2018) Jin Gu Cho et al.   Frontiers in Immunology

Transcriptome Analysis Reveals Nonfoamy Rather Than Foamy Plaque Macrophages Are Proinflammatory in Atherosclerotic Murine Models

(2018) Kyeongdae Kim et al.   CIRCULATION RESEARCH

A Defective Pentose Phosphate Pathway Reduces Inflammatory Macrophage Responses during Hypercholesterolemia

(2018) Jeroen Baardman et al.   Cell Reports

Role of NLRP3 Inflammasomes in Atherosclerosis

(2017) Tadayoshi Karasawa et al.   Journal of Atherosclerosis and Thrombosis

Association analyses based on false discovery rate implicate new loci for coronary artery disease

(2017) Christopher P Nelson et al.   NATURE GENETICS

chromVAR: inferring transcription-factor-associated accessibility from single-cell epigenomic data

(2017) Alicia N Schep et al.   NATURE METHODS

Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

(2017) Paul M Ridker et al.   NEW ENGLAND JOURNAL OF MEDICINE

JASPAR 2018: update of the open-access database of transcription factor binding profiles and its web framework

(2017) Aziz Khan et al.   NUCLEIC ACIDS RESEARCH

Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors

(2017) Alexandra-Chloé Villani et al.   SCIENCE

Functional mapping and annotation of genetic associations with FUMA

(2017) Kyoko Watanabe et al.   Nature Communications

Macrophage Phenotype and Function in Different Stages of Atherosclerosis

(2016) Ira Tabas et al.   CIRCULATION RESEARCH

Interleukins (from IL-1 to IL-38), interferons, transforming growth factor β, and TNF-α: Receptors, functions, and roles in diseases

(2016) Mübeccel Akdis et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Macrophages: An Inflammatory Link Between Angiogenesis and Lymphangiogenesis

(2016) Bruce A. Corliss et al.   MICROCIRCULATION

Expression profiling of constitutive mast cells reveals a unique identity within the immune system

(2016) Daniel F Dwyer et al.   NATURE IMMUNOLOGY

Cytotoxic CD4 T Cells: Differentiation, Function, and Application to Dengue Virus Infection

(2016) Yuan Tian et al.   Frontiers in Immunology

A Single-Cell Transcriptome Atlas of the Human Pancreas

(2016) Mauro J. Muraro et al.   Cell Systems

MFAP4 Promotes Vascular Smooth Muscle Migration, Proliferation and Accelerates Neointima Formation

(2015) Anders Schlosser et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Endothelial-to-mesenchymal transition drives atherosclerosis progression

(2015) Pei-Yu Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

Transcription Factors STAT6 and KLF4 Implement Macrophage Polarization via the Dual Catalytic Powers of MCPIP

(2015) Nidhi Kapoor et al.   JOURNAL OF IMMUNOLOGY

A global reference for human genetic variation

(2015) Richard A. Gibbs et al.   NATURE

KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis

(2015) Laura S Shankman et al.   NATURE MEDICINE

Dynamic recruitment of Ets1 to both nucleosome-occupied and -depleted enhancer regions mediates a transcriptional program switch during early T-cell differentiation

(2015) Pierre Cauchy et al.   NUCLEIC ACIDS RESEARCH

MAGMA: Generalized Gene-Set Analysis of GWAS Data

(2015) Christiaan A. de Leeuw et al.   PLoS Computational Biology

Type 2 diabetes is not associated with an altered plaque phenotype among patients undergoing carotid revascularization. A histological analysis of 1455 carotid plaques

(2014) Vincent P.W. Scholtes et al.   ATHEROSCLEROSIS

ATP-Binding Cassette Transporters, Atherosclerosis, and Inflammation

(2014) Marit Westerterp et al.   CIRCULATION RESEARCH

The transcription factor BATF operates as an essential differentiation checkpoint in early effector CD8+ T cells

(2014) Makoto Kurachi et al.   NATURE IMMUNOLOGY

Human Dendritic Cell Functional Specialization in Steady-State and Inflammation

(2014) Arjan Boltjes et al.   Frontiers in Immunology

Prolylcarboxypeptidase promotes angiogenesis and vascular repair

(2013) G. N. Adams et al.   BLOOD

Characterization of CD4+CD28null T cells in patients with coronary artery disease and individuals with risk factors for atherosclerosis

(2013) Fábio Haach Téo et al.   CELLULAR IMMUNOLOGY

BLUEPRINT: mapping human blood cell epigenomes

(2013) J. H. A. Martens et al.   HAEMATOLOGICA

Transcriptional reprogramming of mature CD4+ helper T cells generates distinct MHC class II–restricted cytotoxic T lymphocytes

(2013) Daniel Mucida et al.   NATURE IMMUNOLOGY

Mutual expression of the transcription factors Runx3 and ThPOK regulates intestinal CD4+ T cell immunity

(2013) Bernardo Sgarbi Reis et al.   NATURE IMMUNOLOGY

Expression of the B-Cell Receptor Component CD79a on Immature Myeloid Cells Contributes to Their Tumor Promoting Effects

(2013) Dror Luger et al.   PLoS One

Distribution of macrophage polarization markers in human atherosclerosis

(2012) J. Lauran Stöger et al.   ATHEROSCLEROSIS

NFAT control of innate immunity

(2012) J. Fric et al.   BLOOD

Regulated Accumulation of Desmosterol Integrates Macrophage Lipid Metabolism and Inflammatory Responses

(2012) Nathanael J. Spann et al.   CELL

Molecular Pathways Regulating Macrophage Polarization: Implications for Atherosclerosis

(2012) Marten A. Hoeksema et al.   Current Atherosclerosis Reports

Nuclear presence of nuclear factor of activated T cells (NFAT) c3 and c4 is required for Toll-like receptor-activated innate inflammatory response of monocytes/macrophages

(2011) Hiroshi Minematsu et al.   CELLULAR SIGNALLING

GATA3 controls Foxp3+ regulatory T cell fate during inflammation in mice

(2011) Elizabeth A. Wohlfert et al.   JOURNAL OF CLINICAL INVESTIGATION

Toll-like Receptor 4 Mediates Oxidized LDL-Induced Macrophage Differentiation to Foam Cells

(2011) Kenneth W. Howell et al.   JOURNAL OF SURGICAL RESEARCH

Dendritic Cells in Human Atherosclerosis: From Circulation to Atherosclerotic Plaques

(2011) Emily A. Van Vré et al.   MEDIATORS OF INFLAMMATION

Fast and accurate long-read alignment with Burrows–Wheeler transform

(2010) Heng Li et al.   BIOINFORMATICS

Nomenclature of monocytes and dendritic cells in blood

(2010) L. Ziegler-Heitbrock et al.   BLOOD

Myeloid Type I Interferon Signaling Promotes Atherosclerosis by Stimulating Macrophage Recruitment to Lesions

(2010) Pieter Goossens et al.   Cell Metabolism

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

(2010) Peter Duewell et al.   NATURE

The natural history of aortic atherosclerosis: A systematic histopathological evaluation of the peri-renal region

(2009) R.A. van Dijk et al.   ATHEROSCLEROSIS

Toll-Like Receptor-2 Mediates Inflammation and Matrix Degradation in Human Atherosclerosis

(2009) Claudia Monaco et al.   CIRCULATION

Lipoprotein Accumulation in Macrophages via Toll-Like Receptor-4–Dependent Fluid Phase Uptake

(2009) Soo-Ho Choi et al.   CIRCULATION RESEARCH

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

(2009) Cameron R Stewart et al.   NATURE IMMUNOLOGY

Carotid Atherosclerotic Plaques Stabilize After Stroke

(2008) W. Peeters et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

B lymphocytes: how they develop and function

(2008) T. W. LeBien et al.   BLOOD

Notch Signaling Regulates Platelet-Derived Growth Factor Receptor-β Expression in Vascular Smooth Muscle Cells

(2008) Shaobo Jin et al.   CIRCULATION RESEARCH

Oxidation-specific epitopes are important targets of innate immunity

(2008) M.-Y. Chou et al.   JOURNAL OF INTERNAL MEDICINE

Histological Characterization of Restenotic Carotid Plaques in Relation to Recurrence Interval and Clinical Presentation

(2008) Willem E. Hellings et al.   STROKE