Single-cell immune landscape of human atherosclerotic plaques

Hematopoietic Deficiency of the Long Non-Coding RNA MALAT1 Promotes Atherosclerosis and Plaque Inflammation

(2019) Sebastian Cremer et al.   CIRCULATION

Interleukin-35 Promotes Macrophage Survival and Improves Wound Healing After Myocardial Infarction in Mice

(2019) Daile Jia et al.   CIRCULATION RESEARCH

Development of a Comprehensive Antibody Staining Database Using a Standardized Analytics Pipeline

(2019) El-ad David Amir et al.   Frontiers in Immunology

LncRNA MALAT1 regulates oxLDL-induced CD36 expression via activating β-catenin

(2018) Ning Huangfu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Immune cell census in murine atherosclerosis: cytometry by time of flight illuminates vascular myeloid cell diversity

(2018) Jennifer E Cole et al.   CARDIOVASCULAR RESEARCH

Single-Cell Map of Diverse Immune Phenotypes in the Breast Tumor Microenvironment

(2018) Elham Azizi et al.   CELL

Single-Cell RNA-Seq Reveals the Transcriptional Landscape and Heterogeneity of Aortic Macrophages in Murine AtherosclerosisNovelty and Significance

(2018) Clément Cochain et al.   CIRCULATION RESEARCH

Atlas of the Immune Cell Repertoire in Mouse Atherosclerosis Defined by Single-Cell RNA-Sequencing and Mass CytometryNovelty and Significance

(2018) Holger Winkels et al.   CIRCULATION RESEARCH

Anti-fibrotic effects of pirfenidone by interference with the hedgehog signalling pathway in patients with systemic sclerosis-associated interstitial lung disease

(2018) Hua Xiao et al.   International Journal of Rheumatic Diseases

CD163+ macrophages promote angiogenesis and vascular permeability accompanied by inflammation in atherosclerosis

(2018) Liang Guo et al.   JOURNAL OF CLINICAL INVESTIGATION

Batch effects in single-cell RNA-sequencing data are corrected by matching mutual nearest neighbors

(2018) Laleh Haghverdi et al.   NATURE BIOTECHNOLOGY

Phenotype molding of stromal cells in the lung tumor microenvironment

(2018) Diether Lambrechts et al.   NATURE MEDICINE

Update on Cardiovascular Disease Risk in Patients with Rheumatic Diseases

(2018) Rachel H. Mackey et al.   RHEUMATIC DISEASE CLINICS OF NORTH AMERICA

Interleukin-2 shapes the cytotoxic T cell proteome and immune environment–sensing programs

(2018) Christina M. Rollings et al.   Science Signaling

Interleukin-2 shapes the cytotoxic T cell proteome and immune environment–sensing programs

(2018) Christina M. Rollings et al.   Science Signaling

GDF11 antagonizes TNF-α–induced inflammation and protects against the development of inflammatory arthritis in mice

(2018) Weiwei Li et al.   FASEB JOURNAL

Low-Dose Methotrexate for the Prevention of Atherosclerotic Events

(2018) Paul M Ridker et al.   NEW ENGLAND JOURNAL OF MEDICINE

Analysis of Single-Cell RNA-Seq Identifies Cell-Cell Communication Associated with Tumor Characteristics

(2018) Manu P. Kumar et al.   Cell Reports

Monocyte-Macrophages and T Cells in Atherosclerosis

(2017) Ira Tabas et al.   IMMUNITY

Scaling single-cell genomics from phenomenology to mechanism

(2017) Amos Tanay et al.   NATURE

Simultaneous epitope and transcriptome measurement in single cells

(2017) Marlon Stoeckius et al.   NATURE METHODS

Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

(2017) Paul M Ridker et al.   NEW ENGLAND JOURNAL OF MEDICINE

Rescue of exhausted CD8 T cells by PD-1–targeted therapies is CD28-dependent

(2017) Alice O. Kamphorst et al.   SCIENCE

Human Tissue-Resident Memory T Cells Are Defined by Core Transcriptional and Functional Signatures in Lymphoid and Mucosal Sites

(2017) Brahma V. Kumar et al.   Cell Reports

Clustergrammer, a web-based heatmap visualization and analysis tool for high-dimensional biological data

(2017) Nicolas F. Fernandez et al.   Scientific Data

Protective and pathogenic roles of CD8+ T cells in atherosclerosis

(2016) Clement Cochain et al.   BASIC RESEARCH IN CARDIOLOGY

IL-2, IL-7, and IL-15: Multistage regulators of CD4+ T helper cell differentiation

(2016) Kaitlin A. Read et al.   EXPERIMENTAL HEMATOLOGY

Enrichr: a comprehensive gene set enrichment analysis web server 2016 update

(2016) Maxim V. Kuleshov et al.   NUCLEIC ACIDS RESEARCH

Animal models for plaque rupture: a biomechanical assessment

(2016) Mat J. Daemen et al.   THROMBOSIS AND HAEMOSTASIS

Data-Driven Phenotypic Dissection of AML Reveals Progenitor-like Cells that Correlate with Prognosis

(2015) Jacob H. Levine et al.   CELL

A CD45-based barcoding approach to multiplex mass-cytometry (CyTOF)

(2015) Liyun Lai et al.   CYTOMETRY PART A

T-cell receptor profiling in cancer

(2015) Ilan Kirsch et al.   Molecular Oncology

A draft network of ligand–receptor-mediated multicellular signalling in human

(2015) Jordan A. Ramilowski et al.   Nature Communications

The Role of An Experimental Model of Atherosclerosis: apoE-knockout Mice in Developing New Drugs against Atherogenesis

(2015) Jacek Jawien   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Mechanism of NLRP3 inflammasome activation

(2014) Fayyaz S. Sutterwala et al.   Annals of the New York Academy of Sciences

IL15RA Drives Antagonistic Mechanisms of Cancer Development and Immune Control in Lymphocyte-Enriched Triple-Negative Breast Cancers

(2014) Pierfrancesco Marra et al.   CANCER RESEARCH

Epidemiology, risk factors and management of cardiovascular diseases in IBD

(2014) Siddharth Singh et al.   Nature Reviews Gastroenterology & Hepatology

IL-21 Enhances Phagocytosis in Mononuclear Phagocyte Cells: Identification of Spleen Tyrosine Kinase as a Novel Molecular Target of IL-21

(2013) F. Vallieres et al.   JOURNAL OF IMMUNOLOGY

Monocytes in Coronary Artery Disease and Atherosclerosis

(2013) Angie Ghattas et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The effects of lowering LDL cholesterol with statin therapy in people at low risk of vascular disease: meta-analysis of individual data from 27 randomised trials

(2013)   LANCET

viSNE enables visualization of high dimensional single-cell data and reveals phenotypic heterogeneity of leukemia

(2013) El-ad David Amir et al.   NATURE BIOTECHNOLOGY

Using synthetic templates to design an unbiased multiplex PCR assay

(2013) Christopher S. Carlson et al.   Nature Communications

High Levels of Costimulatory Receptors OX40 and 4-1BB Characterize CD4 + CD28 null T Cells in Patients With Acute Coronary Syndrome

(2012) Ingrid E. Dumitriu et al.   CIRCULATION RESEARCH

A platinum-based covalent viability reagent for single-cell mass cytometry

(2012) Harris G. Fienberg et al.   CYTOMETRY PART A

Notch signaling regulates PD-1 expression during CD8+ T-cell activation

(2012) Mélissa Mathieu et al.   IMMUNOLOGY AND CELL BIOLOGY

β-Catenin/TCF-1 Pathway in T Cell Development and Differentiation

(2012) Jian Ma et al.   Journal of Neuroimmune Pharmacology

Opposing roles for RhoH GTPase during T-cell migration and activation

(2012) C. M. Baker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impairment of the Programmed Cell Death-1 Pathway Increases Atherosclerotic Lesion Development and Inflammation

(2011) De-xiu Bu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Macrophages in the Pathogenesis of Atherosclerosis

(2011) Kathryn J. Moore et al.   CELL

CD8+ CD28− and CD8+ CD57+ T cells and their role in health and disease

(2011) Marius Strioga et al.   IMMUNOLOGY

RANTES/CCL5 and Risk for Coronary Events: Results from the MONICA/KORA Augsburg Case-Cohort, Athero-Express and CARDIoGRAM Studies

(2011) Christian Herder et al.   PLoS One

Concept of Vulnerable/Unstable Plaque

(2010) Aloke V. Finn et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

T-cell exhaustion: characteristics, causes and conversion

(2010) John S. Yi et al.   IMMUNOLOGY

Expression of lipoprotein-associated phospholipase A2 in carotid artery plaques predicts long-term cardiac outcome

(2009) J. Herrmann et al.   EUROPEAN HEART JOURNAL

Regulation of Macrophage Functions by PPAR-α, PPAR-γ, and LXRs in Mice and Men

(2008) Elena Rigamonti et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Interleukin-8 is increased in the membrane of circulating erythrocytes in patients with acute coronary syndrome

(2008) D. N. Tziakas et al.   EUROPEAN HEART JOURNAL

Fast unfolding of communities in large networks

(2008) Vincent D Blondel et al.   JOURNAL OF STATISTICAL MECHANICS-THEORY AND EXPERIMENT