Lactate Inhibits the Pro-Inflammatory Response and Metabolic Reprogramming in Murine Macrophages in a GPR81-Independent Manner

Metabolic reprogramming in macrophages and dendritic cells in innate immunity

(2015) Beth Kelly et al.   CELL RESEARCH

A Broken Krebs Cycle in Macrophages

(2015) Luke A.J. O’Neill   IMMUNITY

Network Integration of Parallel Metabolic and Transcriptional Data Reveals Metabolic Modules that Regulate Macrophage Polarization

(2015) Abhishek K. Jha et al.   IMMUNITY

Infection with Mycobacterium tuberculosis induces the Warburg effect in mouse lungs

(2015) Lanbo Shi et al.   Scientific Reports

Modeling Alveolar Soft Part Sarcomagenesis in the Mouse: A Role for Lactate in the Tumor Microenvironment

(2014) Matthew L. Goodwin et al.   CANCER CELL

Lactate Reduces Liver and Pancreatic Injury in Toll-Like Receptor– and Inflammasome-Mediated Inflammation via GPR81-Mediated Suppression of Innate Immunity

(2014) Rafaz Hoque et al.   GASTROENTEROLOGY

Diet, Metabolites, and “Western-Lifestyle” Inflammatory Diseases

(2014) Alison N. Thorburn et al.   IMMUNITY

The Monocarboxylate Transporter 4 Is Required for Glycolytic Reprogramming and Inflammatory Response in Macrophages

(2014) Zheng Tan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional polarization of tumour-associated macrophages by tumour-derived lactic acid

(2014) Oscar R. Colegio et al.   NATURE

HR-MAS MRS of the pancreas reveals reduced lipid and elevated lactate and taurine associated with early pancreatic cancer

(2014) Alan S. Wang et al.   NMR IN BIOMEDICINE

Quantitative Measurement of Organic Acids in Tissues from Gastric Cancer Patients Indicates Increased Glucose Metabolism in Gastric Cancer

(2014) Hoon Hur et al.   PLoS One

Links between diet, gut microbiota composition and gut metabolism

(2014) Harry J. Flint et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

Disarmed by density

(2014) Aikaterini Nasi et al.   OncoImmunology

Free Fatty Acid (FFA) and Hydroxy Carboxylic Acid (HCA) Receptors

(2013) Stefan Offermanns   Annual Review of Pharmacology and Toxicology

Blocking Lactate Export by Inhibiting the Myc Target MCT1 Disables Glycolysis and Glutathione Synthesis

(2013) J. R. Doherty et al.   CANCER RESEARCH

Airway structural cells regulate TLR5-mediated mucosal adjuvant activity

(2013) L Van Maele et al.   Mucosal Immunology

Vaginal pH and Microbicidal Lactic Acid When Lactobacilli Dominate the Microbiota

(2013) Deirdre E. O’Hanlon et al.   PLoS One

Microbiota-derived lactate accelerates colon epithelial cell turnover in starvation-refed mice

(2013) Toshihiko Okada et al.   Nature Communications

Metabolomic profiling of lung and prostate tumor tissues by capillary electrophoresis time-of-flight mass spectrometry

(2012) Kenjiro Kami et al.   Metabolomics

G protein-coupled receptors for energy metabolites as new therapeutic targets

(2012) Clara C. Blad et al.   NATURE REVIEWS DRUG DISCOVERY

The monocarboxylate transporter family-Role and regulation

(2011) Andrew P. Halestrap et al.   IUBMB LIFE

Metabolic Profiling of Lung Granuloma inMycobacterium tuberculosisInfected Guinea Pigs: Ex vivo1H Magic Angle Spinning NMR Studies

(2011) B. S. Somashekar et al.   JOURNAL OF PROTEOME RESEARCH

An Autocrine Lactate Loop Mediates Insulin-Dependent Inhibition of Lipolysis through GPR81

(2010) Kashan Ahmed et al.   Cell Metabolism

Probiotic Lactobacillus casei strain Shirota prevents indomethacin-induced small intestinal injury: involvement of lactic acid

(2009) Toshio Watanabe et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Quantitative Metabolome Profiling of Colon and Stomach Cancer Microenvironment by Capillary Electrophoresis Time-of-Flight Mass Spectrometry

(2009) A. Hirayama et al.   CANCER RESEARCH

Lactic Acid and Acidification Inhibit TNF Secretion and Glycolysis of Human Monocytes

(2009) K. Dietl et al.   JOURNAL OF IMMUNOLOGY

Lactate Inhibits Lipolysis in Fat Cells through Activation of an Orphan G-protein-coupled Receptor, GPR81

(2008) Changlu Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY