Amyloid and Amyloid-Like Aggregates: Diversity and the Term Crisis

Functional amyloids of eukaryotes: criteria, classification, and biological significance

(2020) Aleksandra V. Sergeeva et al.   CURRENT GENETICS

Liquid–Liquid Phase Separation and Its Mechanistic Role in Pathological Protein Aggregation

(2020) W. Michael Babinchak et al.   JOURNAL OF MOLECULAR BIOLOGY

Kinetic diversity of amyloid oligomers

(2020) Alexander J. Dear et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cryo-EM structure of a neuronal functional amyloid implicated in memory persistence in Drosophila

(2020) Ruben Hervas et al.   SCIENCE

Amyloid nomenclature 2018: recommendations by the International Society of Amyloidosis (ISA) nomenclature committee

(2019) Merrill D. Benson et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Molecular Mechanisms of TDP-43 Misfolding and Pathology in Amyotrophic Lateral Sclerosis

(2019) Archana Prasad et al.   Frontiers in Molecular Neuroscience

The Gln3 Transcriptional Regulator of Saccharomyces cerevisiae Manifests Prion-Like Properties upon Overproduction

(2019) K. S. Antonets et al.   BIOCHEMISTRY-MOSCOW

The pathology and changing epidemiology of Dialysis-related cardiac Beta-2 microglobulin amyloidosis

(2019) Allison D. Morris et al.   CARDIOVASCULAR PATHOLOGY

Fused in Sarcoma: Properties, Self-Assembly and Correlation with Neurodegenerative Diseases

(2019) Chen Chen et al.   MOLECULES

Stochasticity of Biological Soft Matter: Emerging Concepts in Intrinsically Disordered Proteins and Biological Phase Separation

(2019) Konstantin K. Turoverov et al.   TRENDS IN BIOCHEMICAL SCIENCES

Structural basis for reversible amyloids of hnRNPA1 elucidates their role in stress granule assembly

(2019) Xinrui Gui et al.   Nature Communications

Intrinsic Disorder-Based Emergence in Cellular Biology: Physiological and Pathological Liquid-Liquid Phase Transitions in Cells

(2019) April L. Darling et al.   Polymers

Supramolecular Fuzziness of Intracellular Liquid Droplets: Liquid–Liquid Phase Transitions, Membrane-Less Organelles, and Intrinsic Disorder

(2019) Vladimir N. Uversky   MOLECULES

A Non-amyloid Prion Particle that Activates a Heritable Gene Expression Program

(2019) Anupam K. Chakravarty et al.   MOLECULAR CELL

Two Novel Amyloid Proteins, RopA and RopB, from the Root Nodule Bacterium Rhizobium leguminosarum

(2019) Kosolapova et al.   Biomolecules

Protein Misfolding during Pregnancy: New Approaches to Preeclampsia Diagnostics

(2019) Elizaveta M. Gerasimova et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Proteinase K resistant cores of prions and amyloids

(2019) Vitaly V. Kushnirov et al.   Prion

RNA-binding protein FXR1 is presented in rat brain in amyloid form

(2019) Julia V. Sopova et al.   Scientific Reports

Phosphorylation-Mediated Clearance of Amyloid-like Assemblies in Meiosis

(2018) Kayla Carpenter et al.   DEVELOPMENTAL CELL

Tau protein liquid–liquid phase separation can initiate tau aggregation

(2018) Susanne Wegmann et al.   EMBO JOURNAL

SOD1 in Amyotrophic Lateral Sclerosis: “Ambivalent” Behavior Connected to the Disease

(2018) Orietta Pansarasa et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mammalian amyloidogenic proteins promote prion nucleation in yeast

(2018) Pavithra Chandramowlishwaran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloid assembly and disassembly

(2018) Edward Chuang et al.   JOURNAL OF CELL SCIENCE

Atomic structures of FUS LC domain segments reveal bases for reversible amyloid fibril formation

(2018) Feng Luo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

M60-like metalloprotease domain of the Escherichia coli YghJ protein forms amyloid fibrils

(2018) Mikhail V. Belousov et al.   PLoS One

Atomic structures of low-complexity protein segments reveal kinked β sheets that assemble networks

(2018) Michael P. Hughes et al.   SCIENCE

Phase separation of a yeast prion protein promotes cellular fitness

(2018) Titus M. Franzmann et al.   SCIENCE

Atomic structures of FUS LC domain segments reveal bases for reversible amyloid fibril formation

(2018) Feng Luo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The molecular language of membraneless organelles

(2018) Edward Gomes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Staphylococcus epidermidis small basic protein (Sbp) forms amyloid fibrils, consistent with its function as a scaffolding protein in biofilms

(2018) Yan Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A new era for understanding amyloid structures and disease

(2018) Matthew G. Iadanza et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mycobacterium tuberculosis CarD, an essential global transcriptional regulator forms amyloid-like fibrils

(2018) Gundeep Kaur et al.   Scientific Reports

Prions and Non-infectious Amyloids of Mammals – Similarities and Differences

(2018) A. P. Galkin et al.   BIOCHEMISTRY-MOSCOW

Congo Red and amyloids: history and relationship

(2018) Elmira I. Yakupova et al.   BIOSCIENCE REPORTS

Nucleation and growth of pores in 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) / cholesterol bilayer by antimicrobial peptides melittin, its mutants and cecropin P1

(2018) Yuan Lyu et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Porins and Amyloids are Coded by Similar Sequence Motifs

(2018) Etienne Villain et al.   PROTEOMICS

Systemic immunoglobulin light chain amyloidosis

(2018) Giampaolo Merlini et al.   Nature Reviews Disease Primers

Peptidoglycan-Sensing Receptors Trigger the Formation of Functional Amyloids of the Adaptor Protein Imd to Initiate Drosophila NF-κB Signaling

(2017) Anni Kleino et al.   IMMUNITY

The wisdom of crowds: regulating cell function through condensed states of living matter

(2017) Simon Alberti   JOURNAL OF CELL SCIENCE

Functional amyloids in Streptococcus mutans, their use as targets of biofilm inhibition and initial characterization of SMU_63c

(2017) Richard N Besingi et al.   MICROBIOLOGY-SGM

Structural variation in amyloid-β fibrils from Alzheimer's disease clinical subtypes

(2017) Wei Qiang et al.   NATURE

Intrinsically Disordered Proteome of Human Membrane-Less Organelles

(2017) April L. Darling et al.   PROTEOMICS

The cytotoxic Staphylococcus aureus PSMα3 reveals a cross-α amyloid-like fibril

(2017) Einav Tayeb-Fligelman et al.   SCIENCE

Yeast Short-Lived Actin-Associated Protein Forms a Metastable Prion in Response to Thermal Stress

(2017) Tatiana A. Chernova et al.   Cell Reports

The Synucleinopathies: Twenty Years On

(2017) Michel Goedert et al.   Journal of Parkinsons Disease

Regulated Forms of Cell Death in Fungi

(2017) A. Pedro Gonçalves et al.   Frontiers in Microbiology

Alzheimer's Disease and the Amyloid-β Peptide

(2017) M. Paul Murphy et al.   JOURNAL OF ALZHEIMERS DISEASE

Proteomic analysis of Escherichia coli protein fractions resistant to solubilization by ionic detergents

(2016) K. S. Antonets et al.   BIOCHEMISTRY-MOSCOW

Haploid yeast cells undergo a reversible phenotypic switch associated with chromosome II copy number

(2016) Polina Drozdova et al.   BMC GENETICS

Amyloid-like Self-Assembly of a Cellular Compartment

(2016) Elvan Boke et al.   CELL

Intrinsically Disordered Proteins Drive Emergence and Inheritance of Biological Traits

(2016) Sohini Chakrabortee et al.   CELL

Phase separation in biology; functional organization of a higher order

(2016) Diana M. Mitrea et al.   Cell Communication and Signaling

Adaptation to Stressors by Systemic Protein Amyloidogenesis

(2016) Timothy E. Audas et al.   DEVELOPMENTAL CELL

A common ‘aggregation-prone’ interface possibly participates in the self-assembly of human zona pellucida proteins

(2016) Nikolaos N. Louros et al.   FEBS LETTERS

SFP1-mediated prion-dependent lethality is caused by increased Sup35 aggregation and alleviated by Sis1

(2016) Andrew G. Matveenko et al.   GENES TO CELLS

Antimicrobial peptide (Cn-AMP2) from liquid endosperm ofCocos nuciferaforms amyloid-like fibrillar structure

(2016) Shalini Gour et al.   JOURNAL OF PEPTIDE SCIENCE

Identification of a novel cell death-inducing domain reveals that fungal amyloid-controlled programmed cell death is related to necroptosis

(2016) Asen Daskalov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interaction of Prions Causes Heritable Traits in Saccharomyces cerevisiae

(2016) Anton A. Nizhnikov et al.   PLoS Genetics

Staphylococcal Bap Proteins Build Amyloid Scaffold Biofilm Matrices in Response to Environmental Signals

(2016) Agustina Taglialegna et al.   PLoS Pathogens

Self-assembly of MPG1, a hydrophobin protein from the rice blast fungus that forms functional amyloid coatings, occurs by a surface-driven mechanism

(2016) Chi L. L. Pham et al.   Scientific Reports

Amyloids: from pathogenesis to function

(2015) A. A. Nizhnikov et al.   BIOCHEMISTRY-MOSCOW

Outer membrane protein C (OmpC) of Escherichia coli induces neurodegeneration in mice by acting as an amyloid

(2015) J. Joseph Sahaya Rajan et al.   BIOTECHNOLOGY LETTERS

Ion and seed dependent fibril assembly of a spidroin core domain

(2015) Martin Humenik et al.   JOURNAL OF STRUCTURAL BIOLOGY

A new prion disease: relationship with central and peripheral amyloidoses

(2015) Simon Mead et al.   Nature Reviews Neurology

Amyloidogenesis of Bacterial Prionoid RepA-WH1 Recapitulates Dimer to Monomer Transitions of RepA in DNA Replication Initiation

(2015) Eva Torreira et al.   STRUCTURE

The CPEB3 Protein Is a Functional Prion that Interacts with the Actin Cytoskeleton

(2015) Joseph S. Stephan et al.   Cell Reports

Amyloid Properties of the Mouse Egg Zona Pellucida

(2015) Nathan Egge et al.   PLoS One

Aqueous, Unfolded OmpA Forms Amyloid-Like Fibrils upon Self-Association

(2015) Emily J. Danoff et al.   PLoS One

Modulating Materials by Orthogonally Oriented β-Strands: Composites of Amyloid and Silk Fibroin Fibrils

(2014) Shengjie Ling et al.   ADVANCED MATERIALS

Pharmaceutical amyloidosis associated with subcutaneous insulin and enfuvirtide administration

(2014) Anita D’Souza et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Structural studies of “aggregation-prone” peptide-analogues of teleostean egg chorion ZPB proteins

(2014) Nikolaos N. Louros et al.   BIOPOLYMERS

Distinct roles of RIP1–RIP3 hetero- and RIP3–RIP3 homo-interaction in mediating necroptosis

(2014) X-N Wu et al.   CELL DEATH AND DIFFERENTIATION

Intrinsically disordered proteins as crucial constituents of cellular aqueous two phase systems and coacervates

(2014) Vladimir N. Uversky et al.   FEBS LETTERS

Direct assessment in bacteria of prionoid propagation and phenotype selection by Hsp70 chaperone

(2014) Fátima Gasset-Rosa et al.   MOLECULAR MICROBIOLOGY

The amyloid state and its association with protein misfolding diseases

(2014) Tuomas P. J. Knowles et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Proteomic Screening for Amyloid Proteins

(2014) Anton A. Nizhnikov et al.   PLoS One

Structural mechanism of serum amyloid A-mediated inflammatory amyloidosis

(2014) J. Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression and purification of the aortic amyloid polypeptide medin

(2014) Hannah A. Davies et al.   PROTEIN EXPRESSION AND PURIFICATION

Evolutionary link between metazoan RHIM motif and prion-forming domain of fungal heterokaryon incompatibility factor HET-s/HET-s

(2014) Andrey V. Kajava et al.   Scientific Reports

Alpha-synuclein biology in Lewy body diseases

(2014) Woojin Scott Kim et al.   Alzheimers Research & Therapy

Fungal Hydrophobin Proteins Produce Self-Assembling Protein Films with Diverse Structure and Chemical Stability

(2014) Victor Lo et al.   Nanomaterials

Cell-based Models To Investigate Tau Aggregation

(2014) Sungsu Lim et al.   Computational and Structural Biotechnology Journal

Occurrence of extensive spherical amyloid deposits in a prolactin-secreting pituitary macroadenoma: a radiologic-pathologic correlation

(2013) Steven N. Levine et al.   Annals of Diagnostic Pathology

Homologous Hevea brasiliensis REF (Hevb1) and SRPP (Hevb3) present different auto-assembling

(2013) Karine Berthelot et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

A Super-Assembly of Whi3 Encodes Memory of Deceptive Encounters by Single Cells during Yeast Courtship

(2013) Fabrice Caudron et al.   CELL

Heritable Remodeling of Yeast Multicellularity by an Environmentally Responsive Prion

(2013) Daniel L. Holmes et al.   CELL

Non-targeted Identification of Prions and Amyloid-forming Proteins from Yeast and Mammalian Cells

(2013) Dmitry Kryndushkin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The diagnosis and characteristics of renal heavy-chain and heavy/light-chain amyloidosis and their comparison with renal light-chain amyloidosis

(2013) Samih H. Nasr et al.   KIDNEY INTERNATIONAL

Critical residues in the PMEL/Pmel17 N-terminus direct the hierarchical assembly of melanosomal fibrils

(2013) Ralf M. Leonhardt et al.   MOLECULAR BIOLOGY OF THE CELL

Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS

(2013) Hong Joo Kim et al.   NATURE

A bacterial export system for generating extracellular amyloid aggregates

(2013) Viknesh Sivanathan et al.   Nature Protocols

Guideline of transthyretin-related hereditary amyloidosis for clinicians

(2013) Yukio Ando et al.   Orphanet Journal of Rare Diseases

Biophysical Investigation of the Membrane-Disrupting Mechanism of the Antimicrobial and Amyloid-Like Peptide Dermaseptin S9

(2013) Lucie Caillon et al.   PLoS One

Blessings in disguise: biological benefits of prion-like mechanisms

(2013) Gregory A. Newby et al.   TRENDS IN CELL BIOLOGY

Critical Role of Amyloid-like Oligomers of Drosophila Orb2 in the Persistence of Memory

(2012) Amitabha Majumdar et al.   CELL

Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels

(2012) Masato Kato et al.   CELL

The RIP1/RIP3 Necrosome Forms a Functional Amyloid Signaling Complex Required for Programmed Necrosis

(2012) Jixi Li et al.   CELL

Galectin-7 and actin are components of amyloid deposit of localized cutaneous amyloidosis

(2012) Yoshinori Miura et al.   EXPERIMENTAL DERMATOLOGY

Prions in Yeast

(2012) S. W. Liebman et al.   GENETICS

Rubber Elongation Factor (REF), a Major Allergen Component in Hevea brasiliensis Latex Has Amyloid Properties

(2012) Karine Berthelot et al.   PLoS One

Curli Functional Amyloid Systems Are Phylogenetically Widespread and Display Large Diversity in Operon and Protein Structure

(2012) Morten S. Dueholm et al.   PLoS One

Prion formation by a yeast GLFG nucleoporin

(2012) Randal Halfmann et al.   Prion

Human  -Defensin 6 Promotes Mucosal Innate Immunity Through Self-Assembled Peptide Nanonets

(2012) H. Chu et al.   SCIENCE

A Yeast Prion, Mod5, Promotes Acquired Drug Resistance and Cell Survival Under Environmental Stress

(2012) G. Suzuki et al.   SCIENCE

Prevalence of Isolated Atrial Amyloidosis in Young Patients Affected by Congestive Heart Failure

(2012) Lia Millucci et al.   TheScientificWorldJOURNAL

The Mechanism of Toxicity in HET-S/HET-s Prion Incompatibility

(2012) Carolin Seuring et al.   PLOS BIOLOGY

Antimicrobial Protegrin-1 Forms Amyloid-Like Fibrils with Rapid Kinetics Suggesting a Functional Link

(2011) Hyunbum Jang et al.   BIOPHYSICAL JOURNAL

Destruction of Amyloid Fibrils of Keratoepithelin Peptides by Laser Irradiation Coupled with Amyloid-specific Thioflavin T

(2011) Daisaku Ozawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Recruitment of Class I Hydrophobins to the Air:Water Interface Initiates a Multi-step Process of Functional Amyloid Formation

(2011) Vanessa K. Morris et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Insights into Functional and Pathological Amyloid

(2011) Frank Shewmaker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prion Induction by the Short-Lived, Stress-Induced Protein Lsb2 Is Regulated by Ubiquitination and Association with the Actin Cytoskeleton

(2011) Tatiana A. Chernova et al.   MOLECULAR CELL

Protein-only mechanism induces self-perpetuating changes in the activity of neuronal Aplysia cytoplasmic polyadenylation element binding protein (CPEB)

(2011) S. U. Heinrich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prion diseases of yeast: Amyloid structure and biology

(2011) Reed B. Wickner et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Diversity, biogenesis and function of microbial amyloids

(2011) Luz P. Blanco et al.   TRENDS IN MICROBIOLOGY

Expression of human FUS/TLS in yeast leads to protein aggregation and cytotoxicity, recapitulating key features of FUS proteinopathy

(2011) Kazuo Fushimi et al.   Protein & Cell

Aplysia CPEB Can Form Prion-like Multimers in Sensory Neurons that Contribute to Long-Term Facilitation

(2010) Kausik Si et al.   CELL

[NSI +]: a novel non-Mendelian nonsense suppressor determinant in Saccharomyces cerevisiae

(2010) Alsu F. Saifitdinova et al.   CURRENT GENETICS

A new amyloidosis caused by fibrillar aggregates of mutated corneodesmosin

(2010) Cécile Caubet et al.   FASEB JOURNAL

A DNA-promoted amyloid proteinopathy in Escherichia coli

(2010) M. Elena Fernández-Tresguerres et al.   MOLECULAR MICROBIOLOGY

A causative link between the structure of aberrant protein oligomers and their toxicity

(2010) Silvia Campioni et al.   Nature Chemical Biology

Prion-like transmission of protein aggregates in neurodegenerative diseases

(2010) Patrik Brundin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Amyloid-Like Protein Inclusions in Tobacco Transgenic Plants

(2010) Anna Villar-Piqué et al.   PLoS One

Modeling familial Danish dementia in mice supports the concept of the amyloid hypothesis of Alzheimer's disease

(2010) Janaky Coomaraswamy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Non-Mendelian determinant [ISP+] in yeast is a nuclear-residing prion form of the global transcriptional regulator Sfp1

(2010) T. Rogoza et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amyloidogenic light chains induce cardiomyocyte contractile dysfunction and apoptosis via a non-canonical p38  MAPK pathway

(2010) J. Shi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heterogeneous nuclear ribonucleoproteins (hnRNPs) in cellular processes: Focus on hnRNP E1's multifunctional regulatory roles

(2010) A. Chaudhury et al.   RNA

A Systematic Survey Identifies Prions and Illuminates Sequence Features of Prionogenic Proteins

(2009) Simon Alberti et al.   CELL

An orphan dermaseptin from frog skin reversibly assembles to amyloid-like aggregates in a pH-dependent fashion

(2009) Ruth Gößler-Schöfberger et al.   FEBS Journal

A heritable switch in carbon source utilization driven by an unusual yeast prion

(2009) J. C.S. Brown et al.   GENES & DEVELOPMENT

N-terminal Domains Elicit Formation of Functional Pmel17 Amyloid Fibrils

(2009) Brenda Watt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hereditary Apolipoprotein AI-Associated Amyloidosis in Surgical Pathology Specimens

(2009) Magdalena Eriksson et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

The yeast global transcriptional co-repressor protein Cyc8 can propagate as a prion

(2009) Basant K. Patel et al.   NATURE CELL BIOLOGY

Amyloid Formation by the Pro-Inflammatory S100A8/A9 Proteins in the Ageing Prostate

(2009) Kiran Yanamandra et al.   PLoS One

The repeat domain of the melanosome fibril protein Pmel17 forms the amyloid core promoting melanin synthesis

(2009) R. P. McGlinchey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional Amyloids As Natural Storage of Peptide Hormones in Pituitary Secretory Granules

(2009) S. K. Maji et al.   SCIENCE

Binding of LL-37 to model biomembranes: Insight into target vs host cell recognition

(2008) Rohit Sood et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Structural Basis of Infectious and Non-Infectious Amyloids

(2008) Ulrich Baxa   Current Alzheimer Research

Structural requirements for antimicrobial versus chemoattractant activities for dermaseptin S9

(2008) Constance Auvynet et al.   FEBS Journal

Structures of Human Host Defense Cathelicidin LL-37 and Its Smallest Antimicrobial Peptide KR-12 in Lipid Micelles

(2008) Guangshun Wang   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloid formation by globular proteins under native conditions

(2008) Fabrizio Chiti et al.   Nature Chemical Biology

Newly identified prion linked to the chromatin-remodeling factor Swi1 in Saccharomyces cerevisiae

(2008) Zhiqiang Du et al.   NATURE GENETICS

Spherical amyloid deposition in a prolactin-producing pituitary adenoma

(2008) Sanser Gul et al.   NEUROPATHOLOGY