Non-targeted Identification of Prions and Amyloid-forming Proteins from Yeast and Mammalian Cells

Cytosolic proteins lose solubility as amyloid deposits in a transgenic mouse model of Alzheimer-type amyloidosis

(2013) Guilian Xu et al.   HUMAN MOLECULAR GENETICS

Stress granules as crucibles of ALS pathogenesis

(2013) Yun R. Li et al.   JOURNAL OF CELL BIOLOGY

Blessings in disguise: biological benefits of prion-like mechanisms

(2013) Gregory A. Newby et al.   TRENDS IN CELL BIOLOGY

The [PSI+] Prion Exists as a Dynamic Cloud of Variants

(2013) David A. Bateman et al.   PLoS Genetics

Huntingtin protein interactions altered by polyglutamine expansion as determined by quantitative proteomic analysis

(2012) Tamara Ratovitski et al.   CELL CYCLE

Prions in Yeast

(2012) S. W. Liebman et al.   GENETICS

A yeast model of optineurin proteinopathy reveals a unique aggregation pattern associated with cellular toxicity

(2012) Dmitry Kryndushkin et al.   MOLECULAR MICROBIOLOGY

Synergistic influence of phosphorylation and metal ions on tau oligomer formation and coaggregation with α-synuclein at the single molecule level

(2012) Georg Nübling et al.   Molecular Neurodegeneration

Prions are a common mechanism for phenotypic inheritance in wild yeasts

(2012) Randal Halfmann et al.   NATURE

Strategies for identifying new prions in yeast

(2012) Kyle S. MacLea et al.   Prion

Sex, prions, and plasmids in yeast

(2012) A. C. Kelly et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

De novo design of synthetic prion domains

(2012) J. A. Toombs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Yeast Prion, Mod5, Promotes Acquired Drug Resistance and Cell Survival Under Environmental Stress

(2012) G. Suzuki et al.   SCIENCE

Functional Amyloids Composed of Phenol Soluble Modulins Stabilize Staphylococcus aureus Biofilms

(2012) Kelly Schwartz et al.   PLoS Pathogens

Structural Insights into Functional and Pathological Amyloid

(2011) Frank Shewmaker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An ALS-associated mutation affecting TDP-43 enhances protein aggregation, fibril formation and neurotoxicity

(2011) Weirui Guo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Suicidal [PSI+] is a lethal yeast prion

(2011) R. P. McGlinchey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diversity, biogenesis and function of microbial amyloids

(2011) Luz P. Blanco et al.   TRENDS IN MICROBIOLOGY

Prion Formation and Polyglutamine Aggregation Are Controlled by Two Classes of Genes

(2011) Anita L. Manogaran et al.   PLoS Genetics

TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration

(2010) C. Lagier-Tourenne et al.   HUMAN MOLECULAR GENETICS

Identification of novel filament-forming proteins inSaccharomyces cerevisiaeandDrosophila melanogaster

(2010) Chalongrat Noree et al.   JOURNAL OF CELL BIOLOGY

Optical trapping with high forces reveals unexpected behaviors of prion fibrils

(2010) Jijun Dong et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Molecular Mechanisms and Potential Therapeutical Targets in Huntington's Disease

(2010) Chiara Zuccato et al.   PHYSIOLOGICAL REVIEWS

Interdependence of amyloid formation in yeast

(2010) Valery N. Urakov et al.   Prion

A Systematic Survey Identifies Prions and Illuminates Sequence Features of Prionogenic Proteins

(2009) Simon Alberti et al.   CELL

Compositional Determinants of Prion Formation in Yeast

(2009) J. A. Toombs et al.   MOLECULAR AND CELLULAR BIOLOGY

Widespread reorganization of metabolic enzymes into reversible assemblies upon nutrient starvation

(2009) R. Narayanaswamy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hsp104 and Prion Propagation

(2009) Nina Romanova et al.   PROTEIN AND PEPTIDE LETTERS

Protein inheritance (prions) based on parallel in-register β-sheet amyloid structures

(2008) Reed B. Wickner et al.   BIOESSAYS

Curing of the [URE3] prion by Btn2p, a Batten disease-related protein

(2008) Dmitry S Kryndushkin et al.   EMBO JOURNAL

P bodies promote stress granule assembly inSaccharomyces cerevisiae

(2008) J. Ross Buchan et al.   JOURNAL OF CELL BIOLOGY

Variant-specific [PSI+] Infection Is Transmitted by Sup35 Polymers within [PSI+] Aggregates with Heterogeneous Protein Composition

(2008) Sviatoslav N. Bagriantsev et al.   MOLECULAR BIOLOGY OF THE CELL

Chaperone-dependent amyloid assembly protects cells from prion toxicity

(2008) P. M. Douglas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacterial Inclusion Bodies Contain Amyloid-Like Structure

(2008) Lei Wang et al.   PLOS BIOLOGY

Prion Switching in Response to Environmental Stress

(2008) Jens Tyedmers et al.   PLOS BIOLOGY