Phase separation of a yeast prion protein promotes cellular fitness

Phase behaviour of disordered proteins underlying low density and high permeability of liquid organelles

(2017) Ming-Tzo Wei et al.   Nature Chemistry

Single-molecule electrometry

(2017) Francesca Ruggeri et al.   Nature Nanotechnology

Biomolecular condensates: organizers of cellular biochemistry

(2017) Salman F. Banani et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Liquid phase condensation in cell physiology and disease

(2017) Yongdae Shin et al.   SCIENCE

Intrinsically disordered linkers determine the interplay between phase separation and gelation in multivalent proteins

(2017) Tyler S Harmon et al.   eLife

Polar Positioning of Phase-Separated Liquid Compartments in Cells Regulated by an mRNA Competition Mechanism

(2016) Shambaditya Saha et al.   CELL

A pH-driven transition of the cytoplasm from a fluid- to a solid-like state promotes entry into dormancy

(2016) Matthias Christoph Munder et al.   eLife

Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization

(2015) Amandine Molliex et al.   CELL

A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation

(2015) Avinash Patel et al.   CELL

Dictyostelium discoideumhas a highly Q/N-rich proteome and shows an unusual resilience to protein aggregation

(2015) Liliana Malinovska et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sporadic Distribution of Prion-Forming Ability of Sup35p from Yeasts and Fungi

(2014) H. K. Edskes et al.   GENETICS

Filament formation by metabolic enzymes is a specific adaptation to an advanced state of cellular starvation

(2014) Ivana Petrovska et al.   eLife

The Bacterial Cytoplasm Has Glass-like Properties and Is Fluidized by Metabolic Activity

(2013) Bradley R. Parry et al.   CELL

Rebels with a cause: molecular features and physiological consequences of yeast prions

(2013) David M. Garcia et al.   FEMS YEAST RESEARCH

Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM

(2013) Xueming Li et al.   NATURE METHODS

Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels

(2012) Masato Kato et al.   CELL

The yeast prions [PSI+] and [URE3] are molecular degenerative diseases

(2012) Reed B. Wickner et al.   Prion

Measuring the complete force field of an optical trap

(2011) Marcus Jahnel et al.   OPTICS LETTERS

Suicidal [PSI+] is a lethal yeast prion

(2011) R. P. McGlinchey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenetics in the Extreme: Prions and the Inheritance of Environmentally Acquired Traits

(2010) Randal Halfmann et al.   SCIENCE

Prions, protein homeostasis, and phenotypic diversity

(2010) Randal Halfmann et al.   TRENDS IN CELL BIOLOGY

A Systematic Survey Identifies Prions and Illuminates Sequence Features of Prionogenic Proteins

(2009) Simon Alberti et al.   CELL

Stress granules

(2009) Paul Anderson et al.   CURRENT BIOLOGY

Eukaryotic Stress Granules: The Ins and Outs of Translation

(2009) J. Ross Buchan et al.   MOLECULAR CELL

Germline P Granules Are Liquid Droplets That Localize by Controlled Dissolution/Condensation

(2009) C. P. Brangwynne et al.   SCIENCE