High‐Precision 3D Bio‐Dot Printing to Improve Paracrine Interaction between Multiple Types of Cell Spheroids

Bioprinting of 3D breast epithelial spheroids for human cancer models

(2019) Swathi Swaminathan et al.   Biofabrication

Biofabrication of spatially organised tissues by directing the growth of cellular spheroids within 3D printed polymeric microchambers

(2019) Andrew C. Daly et al.   BIOMATERIALS

Micropocket hydrogel devices for all-in-one formation, assembly, and analysis of aggregate-based tissues

(2019) Lisa Zhao et al.   Biofabrication

Voxelated soft matter via multimaterial multinozzle 3D printing

(2019) Mark A. Skylar-Scott et al.   NATURE

Layer-by-layer cell coating technique using extracellular matrix facilitates rapid fabrication and function of pancreatic β-cell spheroids

(2018) Yasunari Fukuda et al.   BIOMATERIALS

Carcinoma associated fibroblasts (CAFs) promote breast cancer motility by suppressing mammalian Diaphanous-related formin-2 (mDia2)

(2018) Kaitlyn M. Dvorak et al.   PLoS One

Large-scale patterning of single cells and cell clusters in hydrogels

(2018) Xiangyu Gong et al.   Scientific Reports

Scaffold-free three-dimensional cell culturing using magnetic levitation

(2018) Esra Türker et al.   Biomaterials Science

Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids

(2018) Huili Hu et al.   CELL

Jammed Microgel Inks for 3D Printing Applications

(2018) Christopher B. Highley et al.   Advanced Science

Cell and tissue-based in vitro models for improving the development of oral inhalation drug products

(2017) Marius Hittinger et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Advances in multicellular spheroids formation

(2017) X. Cui et al.   Journal of the Royal Society Interface

Microwell-mediated cell spheroid formation and its applications

(2017) Yu-Shik Hwang et al.   MACROMOLECULAR RESEARCH

Principles of the Kenzan Method for Robotic Cell Spheroid-Based Three-Dimensional Bioprinting

(2017) Nicanor I. Moldovan et al.   TISSUE ENGINEERING PART B-REVIEWS

The Scalable Standardized Biofabrication of Tissue Spheroids from Different Cell Types Using Nonadhesive Technology

(2017) Elizaveta V. Koudan et al.   3D Printing and Additive Manufacturing

Three-dimensional spheroid culture targeting versatile tissue bioassays using a PDMS-based hanging drop array

(2017) Ching-Te Kuo et al.   Scientific Reports

Cell spheroids: the new frontiers in in vitro models for cancer drug validation

(2016) Maria Chatzinikolaidou   DRUG DISCOVERY TODAY

Preparation, characterization, and evaluation of genipin crosslinked chitosan/gelatin three-dimensional scaffolds for liver tissue engineering applications

(2016) Yi Zhang et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Effect of separation distance on the growth and differentiation of mouse embryoid bodies in micropatterned cultures

(2016) Daisuke Miyamoto et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

A 3D bioprinting system to produce human-scale tissue constructs with structural integrity

(2016) Hyun-Wook Kang et al.   NATURE BIOTECHNOLOGY

Culture and establishment of self-renewing human and mouse adult liver and pancreas 3D organoids and their genetic manipulation

(2016) Laura Broutier et al.   Nature Protocols

Spatiotemporal control of cell–cell reversible interactions using molecular engineering

(2016) Peng Shi et al.   Nature Communications

Substrate Stiffness Modulates the Maturation of Human Pluripotent Stem-Cell-Derived Hepatocytes

(2016) Nikhil Mittal et al.   ACS Biomaterials-Science & Engineering

Substrate Stiffness Modulates the Maturation of Human Pluripotent Stem-Cell-Derived Hepatocytes

(2016) Nikhil Mittal et al.   ACS Biomaterials Science & Engineering

Co-Culture of Tumor Spheroids and Fibroblasts in a Collagen Matrix-Incorporated Microfluidic Chip Mimics Reciprocal Activation in Solid Tumor Microenvironment

(2016) Su-Yeong Jeong et al.   PLoS One

Spheroid Formation of Hepatocarcinoma Cells in Microwells: Experiments and Monte Carlo Simulations

(2016) Yan Wang et al.   PLoS One

Microfluidic enrichment for the single cell analysis of circulating tumor cells

(2016) Trifanny Yeo et al.   Scientific Reports

Isolation and co-culture of rat parenchymal and non-parenchymal liver cells to evaluate cellular interactions and response

(2016) Shyam Sundhar Bale et al.   Scientific Reports

Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease

(2016) Catherine C. Bell et al.   Scientific Reports

A microfluidically perfused three dimensional human liver model

(2015) Knut Rennert et al.   BIOMATERIALS

Core-shell hydrogel beads with extracellular matrix for tumor spheroid formation

(2015) L. Yu et al.   Biomicrofluidics

Long-Term Culture of Genome-Stable Bipotent Stem Cells from Adult Human Liver

(2015) Meritxell Huch et al.   CELL

Formation and manipulation of cell spheroids using a density adjusted PEG/DEX aqueous two phase system

(2015) Chungmin Han et al.   Scientific Reports

Networked neural spheroid by neuro-bundle mimicking nervous system created by topology effect

(2015) Gi Seok Jeong et al.   Molecular Brain

Mixed hydrogel bead-based tumor spheroid formation and anticancer drug testing

(2014) Yaolei Wang et al.   ANALYST

Evaluation of Human Hepatocytes Cultured by Three-dimensional Spheroid Systems for Drug Metabolism

(2014) Takako Ohkura et al.   Drug Metabolism and Pharmacokinetics

Micropatterned culture of HepG2 spheroids using microwell chip with honeycomb-patterned polymer film

(2014) Hidekazu Yamazaki et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Effect of Vascular Formed Endothelial Cell Network on the Invasive Capacity of Melanoma Using the In Vitro 3D Co-Culture Patterning Model

(2014) Shuhei Yamamoto et al.   PLoS One

Controlling cell–cell interactions using surface acoustic waves

(2014) Feng Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Colorectal cancer derived organotypic spheroids maintain essential tissue characteristics but adapt their metabolism in culture

(2014) Uros Rajcevic et al.   Proteome Science

Printing three-dimensional tissue analogues with decellularized extracellular matrix bioink

(2014) Falguni Pati et al.   Nature Communications

The generation of pancreatic β-cell spheroids in a simulated microgravity culture system

(2013) Hiroyasu Tanaka et al.   BIOMATERIALS

Spheroid culture as a tool for creating 3D complex tissues

(2013) Eelco Fennema et al.   TRENDS IN BIOTECHNOLOGY

InVERT molding for scalable control of tissue microarchitecture

(2013) K. R. Stevens et al.   Nature Communications

Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation

(2012) Maria Vinci et al.   BMC BIOLOGY

Cell-basedin vitromodels for predicting drug permeability

(2012) Bruno Sarmento et al.   Expert Opinion on Drug Metabolism & Toxicology

High density micromass cultures of a human chondrocyte cell line: A reliable assay system to reveal the modulatory functions of pharmacological agents

(2011) K.V. Greco et al.   BIOCHEMICAL PHARMACOLOGY

Alginate: Properties and biomedical applications

(2011) Kuen Yong Lee et al.   PROGRESS IN POLYMER SCIENCE

High-throughput 3D spheroid culture and drug testing using a 384 hanging drop array

(2010) Yi-Chung Tung et al.   ANALYST

Scaffold-free vascular tissue engineering using bioprinting

(2009) Cyrille Norotte et al.   BIOMATERIALS

Three-dimensional cell culture array using magnetic force-based cell patterning for analysis of invasive capacity of BALB/3T3/v-src

(2009) Mina Okochi et al.   LAB ON A CHIP

Functional Modulation of ES-Derived Hepatocyte Lineage Cells via Substrate Compliance Alteration

(2008) Lulu Li et al.   ANNALS OF BIOMEDICAL ENGINEERING

A new technique for primary hepatocyte expansion in vitro

(2008) Cheul H. Cho et al.   BIOTECHNOLOGY AND BIOENGINEERING