Cells grown in three-dimensional spheroids mirror in vivo metabolic response of epithelial cells

A fast and simple fluorometric method to detect cell death in 3D intestinal organoids

(2019) Konstantin J Bode et al.   BIOTECHNIQUES

mTORC1 Promotes Metabolic Reprogramming by the Suppression of GSK3-Dependent Foxk1 Phosphorylation

(2018) Long He et al.   MOLECULAR CELL

Metabolic characterization of directly reprogrammed renal tubular epithelial cells (iRECs)

(2018) Simon Lagies et al.   Scientific Reports

Metabolic Phenotyping of Anks3 Depletion in mIMCD-3 cells - a Putative Nephronophthisis Candidate

(2018) Manuel Schlimpert et al.   Scientific Reports

A 3D Organotypic Melanoma Spheroid Skin Model

(2018) Ines Müller et al.   Jove-Journal of Visualized Experiments

Identification of a novel anoikis signalling pathway using the fungal virulence factor gliotoxin

(2018) Florian Haun et al.   Nature Communications

Animal testing is still the best way to find new treatments for patients

(2017) Silvio Garattini et al.   European Journal of Internal Medicine

Targeting mTOR Signaling Can Prevent the Progression of FSGS

(2017) Stefan Zschiedrich et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Modeling Physiological Events in 2D vs. 3D Cell Culture

(2017) Kayla Duval et al.   PHYSIOLOGY

E2F1, a Novel Regulator of Metabolism

(2017) Pierre-Damien Denechaud et al.   Frontiers in Endocrinology

3D Bioprinting of Tissue/Organ Models

(2016) Falguni Pati et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Comparison of cancer cells in 2D vs 3D culture reveals differences in AKT–mTOR–S6K signaling and drug responses

(2016) Angelika Riedl et al.   JOURNAL OF CELL SCIENCE

Efficient genome editing of differentiated renal epithelial cells

(2016) Alexis Hofherr et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

3D tumor spheroid models for in vitro therapeutic screening: a systematic approach to enhance the biological relevance of data obtained

(2016) Michele Zanoni et al.   Scientific Reports

High-Content Assays for Characterizing the Viability and Morphology of 3D Cancer Spheroid Cultures

(2015) Oksana Sirenko et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Two-way communication between the metabolic and cell cycle machineries: the molecular basis

(2015) Joanna Kaplon et al.   CELL CYCLE

The tumor-modulatory effects of Caspase-2 and Pidd1 do not require the scaffold protein Raidd

(2015) L Peintner et al.   CELL DEATH AND DIFFERENTIATION

Alternatives to animal testing: A review

(2015) Sonali K. Doke et al.   SAUDI PHARMACEUTICAL JOURNAL

The Hippo-YAP signaling pathway and contact inhibition of growth

(2014) Barry M. Gumbiner et al.   JOURNAL OF CELL SCIENCE

Glucose and glutamine metabolism control by APC and SCF during the G1-to-S phase transition of the cell cycle

(2014) Irving Omar Estévez-García et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Synchronized renal tubular cell death involves ferroptosis

(2014) Andreas Linkermann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The betaine/GABA transporter and betaine: roles in brain, kidney, and liver

(2014) Stephen A. Kempson et al.   Frontiers in Physiology

Understanding Metabolic Regulation and Its Influence on Cell Physiology

(2013) Christian M. Metallo et al.   MOLECULAR CELL

Cerebral organoids model human brain development and microcephaly

(2013) Madeline A. Lancaster et al.   NATURE

Impaired Vitamin D Metabolism in CKD

(2013) Cortney Bosworth et al.   SEMINARS IN NEPHROLOGY

Staying alive

(2012) James R. Valcourt et al.   CELL CYCLE

PIDDosome-independent tumor suppression by Caspase-2

(2012) C Manzl et al.   CELL DEATH AND DIFFERENTIATION

Differences in growth properties of endometrial cancer in three dimensional (3D) culture and 2D cell monolayer

(2012) Kenny Chitcholtan et al.   EXPERIMENTAL CELL RESEARCH

Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation

(2011) Sophia Y. Lunt et al.   Annual Review of Cell and Developmental Biology

E2F transcription factor-1 regulates oxidative metabolism

(2011) Emilie Blanchet et al.   NATURE CELL BIOLOGY

Glucose metabolism in mammalian cell culture: new insights for tweaking vintage pathways

(2010) Bhanu Chandra Mulukutla et al.   TRENDS IN BIOTECHNOLOGY

Quiescent Fibroblasts Exhibit High Metabolic Activity

(2010) Johanna M. S. Lemons et al.   PLOS BIOLOGY