Redox-Sensitive Glyoxalase 1 Up-Regulation Is Crucial for Protecting Human Lung Cells from Gold Nanoparticles Toxicity

Dual role of RACK1 in airway epithelial mesenchymal transition and apoptosis

(2020) Yue Pu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

P38 MAPK and Nrf2 Activation Mediated Naked Gold Nanoparticle Induced Heme Oxygenase-1 Expression in Rat Aortic Vascular Smooth Muscle Cells

(2020) Wen-Chin Ko et al.   ARCHIVES OF MEDICAL RESEARCH

Fractional Exhaled Nitric Oxide and Nanomaterial Exposure in Workplaces

(2020) Ivo Iavicoli et al.   CURRENT MEDICINAL CHEMISTRY

Nimbolide protects against endotoxin-induced acute respiratory distress syndrome by inhibiting TNF-α mediated NF-κB and HDAC-3 nuclear translocation

(2019) Venkatesh Pooladanda et al.   Cell Death & Disease

2-Iodo-4′-Methoxychalcone Attenuates Methylglyoxal-Induced Neurotoxicity by Activation of GLP-1 Receptor and Enhancement of Neurotrophic Signal, Antioxidant Defense and Glyoxalase Pathway

(2019) Yu-Ting Tseng et al.   MOLECULES

Oleuropein-Induced Apoptosis Is Mediated by Mitochondrial Glyoxalase 2 in NSCLC A549 Cells: A Mechanistic Inside and a Possible Novel Nonenzymatic Role for an Ancient Enzyme

(2019) Cinzia Antognelli et al.   Oxidative Medicine and Cellular Longevity

Methylglyoxal Acts as a Tumor-Promoting Factor in Anaplastic Thyroid Cancer

(2019) Cinzia Antognelli et al.   Cells

TET1-mediated DNA hydroxymethylation activates inhibitors of the Wnt/β-catenin signaling pathway to suppress EMT in pancreatic tumor cells

(2019) Jian Wu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Blockade of receptors of advanced glycation end products ameliorates diabetic osteogenesis of adipose-derived stem cells through DNA methylation and Wnt signalling pathway

(2018) Maorui Zhang et al.   CELL PROLIFERATION

KRIT1 loss-of-function induces a chronic Nrf2-mediated adaptive homeostasis that sensitizes cells to oxidative stress: Implication for Cerebral Cavernous Malformation disease

(2018) Cinzia Antognelli et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nicotine induces apoptosis in human osteoblasts via a novel mechanism driven by H 2 O 2 and entailing Glyoxalase 1-dependent MG-H1 accumulation leading to TG2-mediated NF-kB desensitization: Implication for smokers-related osteoporosis

(2018) Lorella Marinucci et al.   FREE RADICAL BIOLOGY AND MEDICINE

Intracellular Transport of Silver and Gold Nanoparticles and Biological Responses: An Update

(2018) Elisa Panzarini et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Glyoxalases in Urological Malignancies

(2018) et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Alteration of MicroRNA Expression Profiles by Surface-Modified Gold Nanoparticles in Human Lung Adenocarcinoma Cells

(2018) Seon Young Choi et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Altered DNA methylation indicates an oscillatory flow mediated epithelial-to-mesenchymal transition signature in ascending aorta of patients with bicuspid aortic valve

(2018) Hanna M. Björck et al.   Scientific Reports

Testosterone and Follicle Stimulating Hormone–Dependent Glyoxalase 1 Up-Regulation Sustains the Viability of Porcine Sertoli Cells through the Control of Hydroimidazolone– and Argpyrimidine-Mediated NF-κB Pathway

(2018) Cinzia Antognelli et al.   AMERICAN JOURNAL OF PATHOLOGY

Transient DNA damage following exposure to gold nanoparticles

(2018) Sarah May et al.   Nanoscale

Targeting dendritic cells through gold nanoparticles: A review on the cellular uptake and subsequent immunological properties

(2017) Suhana Ahmad et al.   MOLECULAR IMMUNOLOGY

DNA methylation variations are required for epithelial-to-mesenchymal transition induced by cancer-associated fibroblasts in prostate cancer cells

(2017) C Pistore et al.   ONCOGENE

Hormetic potential of methylglyoxal, a side-product of glycolysis, in switching tumours from growth to death

(2017) Marie-Julie Nokin et al.   Scientific Reports

DNA Methylation in Cancer and Aging

(2016) M. Klutstein et al.   CANCER RESEARCH

Occupational Risk Assessment of Engineered Nanomaterials: Limits, Challenges and Opportunities

(2016) Veruscka Leso et al.   Current Nanoscience

Glyoxalase I drives epithelial-to-mesenchymal transition via argpyrimidine-modified Hsp70, miR-21 and SMAD signalling in human bronchial cells BEAS-2B chronically exposed to crystalline silica Min-U-Sil 5: Transformation into a neoplastic-like phenotype

(2016) Cinzia Antognelli et al.   FREE RADICAL BIOLOGY AND MEDICINE

Gold nanoparticle size and shape influence on osteogenesis of mesenchymal stem cells

(2016) Jingchao Li et al.   Nanoscale

One low-dose exposure of gold nanoparticles induces long-term changes in human cells

(2016) Priscila Falagan-Lotsch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biomarkers of susceptibility: State of the art and implications for occupational exposure to engineered nanomaterials

(2016) Ivo Iavicoli et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Imaging and radiation effects of gold nanoparticles in tumour cells

(2016) Harold N. McQuaid et al.   Scientific Reports

Uptake, effects, and regeneration of barley plants exposed to gold nanoparticles

(2015) Nadine S. Feichtmeier et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Peroxynitrite-mediated glyoxalase I epigenetic inhibition drives apoptosis in airway epithelial cells exposed to crystalline silica via a novel mechanism involving argpyrimidine-modified Hsp70, JNK, and NF-κB

(2015) Cinzia Antognelli et al.   FREE RADICAL BIOLOGY AND MEDICINE

Gold nanoparticles promote osteogenic differentiation in human adipose-derived mesenchymal stem cells through the Wnt/β-catenin signaling pathway

(2015) So Yeong Lee et al.   International Journal of Nanomedicine

Antioxidant responses and cellular adjustments to oxidative stress

(2015) Cristina Espinosa-Diez et al.   Redox Biology

Glyoxalase I inhibition induces apoptosis in irradiated MCF-7 cells via a novel mechanism involving Hsp27, p53 and NF-κB

(2014) C Antognelli et al.   BRITISH JOURNAL OF CANCER

Melanoma epigenetics: novel mechanisms, markers and medicines

(2014) Jonathan J Lee et al.   LABORATORY INVESTIGATION

Widespread Nanoparticle-Assay Interference: Implications for Nanotoxicity Testing

(2014) Kimberly J. Ong et al.   PLoS One

Size- and time-dependent alteration in metabolic activities of human hepatic cytochrome P450 isozymes by gold nanoparticles via microsomal coincubations

(2014) Meiling Ye et al.   Nanoscale Research Letters

Reactive oxygen species induce apoptosis in bronchial epithelial BEAS-2B cells by inhibiting the antiglycation glyoxalase I defence: involvement of superoxide anion, hydrogen peroxide and NF-κB

(2013) Cinzia Antognelli et al.   APOPTOSIS

Comparing the effects of mitochondrial targeted and localized antioxidants with cellular antioxidants in human skin cells exposed to UVA and hydrogen peroxide

(2013) Anne O. Oyewole et al.   FASEB JOURNAL

Ligand-Assisted Extraction for Separation and Preconcentration of Gold Nanoparticles from Waters

(2012) Lingxiangyu Li et al.   ANALYTICAL CHEMISTRY

Resveratrol Upregulates Nrf2 Expression To Attenuate Methylglyoxal-Induced Insulin Resistance in Hep G2 Cells

(2012) An-Sheng Cheng et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Cytotoxicity and inflammation in human alveolar epithelial cells following exposure to occupational levels of gold and silver nanoparticles

(2012) George D. Bachand et al.   JOURNAL OF NANOPARTICLE RESEARCH

Proteomic Analysis of Protease Resistant Proteins in the Diabetic Rat Kidney

(2012) Sneha B. Bansode et al.   MOLECULAR & CELLULAR PROTEOMICS

Epigenetic Factors in Cancer Risk: Effect of Chemical Carcinogens on Global DNA Methylation Pattern in Human TK6 Cells

(2012) Ali M. Tabish et al.   PLoS One

Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation

(2011) Mingzhan Xue et al.   BIOCHEMICAL JOURNAL

The EMT regulator slug and lung carcinogenesis

(2011) J.-Y. Shih et al.   CARCINOGENESIS

Gold Nanoparticles Promote Osteogenic Differentiation of Mesenchymal Stem Cells through p38 MAPK Pathway

(2010) Changqing Yi et al.   ACS Nano

Glycation of PDGF results in decreased biological activity

(2010) Norbert Nass et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Epigenetics and environmental chemicals

(2009) Andrea Baccarelli et al.   CURRENT OPINION IN PEDIATRICS

Nrf2:INrf2 (Keap1) signaling in oxidative stress

(2009) James W. Kaspar et al.   FREE RADICAL BIOLOGY AND MEDICINE

Analysis of the toxicity of gold nano particles on the immune system: effect on dendritic cell functions

(2009) Christian L. Villiers et al.   JOURNAL OF NANOPARTICLE RESEARCH

Biological applications of gold nanoparticles

(2008) Ralph A. Sperling et al.   CHEMICAL SOCIETY REVIEWS

The relevance of shape and size of Au55 clusters

(2008) Günter Schmid   CHEMICAL SOCIETY REVIEWS