Glyoxalase I inhibition induces apoptosis in irradiated MCF-7 cells via a novel mechanism involving Hsp27, p53 and NF-κB

Ionizing radiation-inducible microRNA miR-193a-3p induces apoptosis by directly targeting Mcl-1

(2013) Jeong-Eun Kwon et al.   APOPTOSIS

Oxidative stress: the mitochondria-dependent and mitochondria-independent pathways of apoptosis

(2013) Krishnendu Sinha et al.   ARCHIVES OF TOXICOLOGY

Equol enhances tamoxifen’s anti-tumor activity by induction of caspase-mediated apoptosis in MCF-7 breast cancer cells

(2013) Christiana Charalambous et al.   BMC CANCER

Differential roles of miR-199a-5p in radiation-induced autophagy in breast cancer cells

(2013) Heqing Yi et al.   FEBS LETTERS

Aging-Dependent Reduction in Glyoxalase 1 Delays Wound Healing

(2013) Thomas H. Fleming et al.   GERONTOLOGY

A novel mechanism of methylglyoxal cytotoxicity in prostate cancer cells

(2013) Cinzia Antognelli et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Mitochondria and Reactive Oxygen Species: Physiology and Pathophysiology

(2013) Subhashini Bolisetty et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Ionizing Radiation Potentiates Dihydroartemisinin-Induced Apoptosis of A549 Cells via a Caspase-8-Dependent Pathway

(2013) Tongsheng Chen et al.   PLoS One

Antineoplastic Effects of α-Santalol on Estrogen Receptor-Positive and Estrogen Receptor-Negative Breast Cancer Cells through Cell Cycle Arrest at G2/M Phase and Induction of Apoptosis

(2013) Sreevidya Santha et al.   PLoS One

Oncomir miR-125b Suppresses p14ARF to Modulate p53-Dependent and p53-Independent Apoptosis in Prostate Cancer

(2013) Sumaira Amir et al.   PLoS One

Prognostic significance of L1CAM in ovarian cancer and its role in constitutive NF-κB activation

(2012) S. Bondong et al.   ANNALS OF ONCOLOGY

Diallyl trisulfide induces apoptosis in human breast cancer cells through ROS-mediated activation of JNK and AP-1

(2012) Hye-Kyung Na et al.   BIOCHEMICAL PHARMACOLOGY

Hodgkin lymphoma requires stabilized NIK and constitutive RelB expression for survival

(2012) S. M. Ranuncolo et al.   BLOOD

Dryofragin, a phloroglucinol derivative, induces apoptosis in human breast cancer MCF-7 cells through ROS-mediated mitochondrial pathway

(2012) Ying Zhang et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Induction of apoptosis in human Hep3B hepatoma cells by norcantharidin through a p53 independent pathway via TRAIL/DR5 signal transduction

(2012) Chung-hsin Yeh et al.   Chinese Journal of Integrative Medicine

Accumulation of argpyrimidine, a methylglyoxal-derived advanced glycation end product, increases apoptosis of lens epithelial cells bothin vitroandin vivo

(2012) Junghyun Kim et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Mechanisms of MPP+-induced PC12 cell apoptosis via reactive oxygen species

(2012) Qing Zhu et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

Role of glyoxalase I in the proliferation and apoptosis control of human LNCaP and PC3 prostate cancer cells

(2012) Cinzia Antognelli et al.   PROSTATE

The convergence of radiation and immunogenic cell death signaling pathways

(2012) Encouse B. Golden et al.   Frontiers in Oncology

Upregulation of CD9 in ovarian cancer is related to the induction of TNF-α gene expression and constitutive NF-κB activation

(2011) Jae Ryoung Hwang et al.   CARCINOGENESIS

Increased glyoxalase I levels inhibit accumulation of oxidative stress and an advanced glycation end product in mouse mesangial cells cultured in high glucose

(2011) Ki Mo Kim et al.   EXPERIMENTAL CELL RESEARCH

Forced Expression of Heat Shock Protein 27 (Hsp27) Reverses P-Glycoprotein (ABCB1)-mediated Drug Efflux andMDR1Gene Expression in Adriamycin-resistant Human Breast Cancer Cells

(2011) Ragu Kanagasabai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A combination of methotrexate and irradiation promotes cell death in NK/T-cell lymphoma cells via down-regulation of NF-κB signaling

(2011) Areumnuri Kim et al.   LEUKEMIA RESEARCH

β-Lapachone Significantly Increases the Effect of Ionizing Radiation to Cause Mitochondrial Apoptosis via JNK Activation in Cancer Cells

(2011) Moon-Taek Park et al.   PLoS One

Methylglyoxal, glyoxalase 1 and the dicarbonyl proteome

(2010) Naila Rabbani et al.   AMINO ACIDS

Intraoperative radiotherapy during breast conserving surgery: a study on 1,822 cases treated with electrons

(2010) Umberto Veronesi et al.   BREAST CANCER RESEARCH AND TREATMENT

Hsp27 Protects Adenocarcinoma Cells from UV-Induced Apoptosis by Akt and p21-Dependent Pathways of Survival

(2010) Ragu Kanagasabai et al.   MOLECULAR CANCER RESEARCH

Up-Regulation of UDP-Glucuronosyltransferase (UGT) 1A4 by 17 -Estradiol: A Potential Mechanism of Increased Lamotrigine Elimination in Pregnancy

(2009) H. Chen et al.   DRUG METABOLISM AND DISPOSITION

Reactive oxygen species induce phosphorylation of serine 118 and 167 on estrogen receptor alpha

(2008) Gregory E. Weitsman et al.   BREAST CANCER RESEARCH AND TREATMENT