Addition of High Molecular Weight Hyaluronic Acid to Fibroblast-Like Stromal Cells Modulates Endogenous Hyaluronic Acid Metabolism and Enhances Proteolytic Processing and Secretion of Versican

Multiple mesenchymal progenitor cell subtypes with distinct functional potential are present within the intimal layer of the hip synovium

(2019) Asmaa Affan et al.   BMC MUSCULOSKELETAL DISORDERS

Adipose‐Derived Stromal Vascular Fraction and Cultured Stromal Cells as Trophic Mediators for Tendon Healing

(2019) Shelley S. Polly et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Compartmentalization and Selective Tagging for Disposal of Misfolded Glycoproteins

(2019) Marina Shenkman et al.   TRENDS IN BIOCHEMICAL SCIENCES

Intracellular hyaluronan: Importance for cellular functions

(2019) Spyros S. Skandalis et al.   SEMINARS IN CANCER BIOLOGY

Preparation and Characterization of Human Adipose Tissue-Derived Extracellular Matrix, Growth Factors, and Stem Cells: A Concise Review

(2019) So Young Chun et al.   Tissue Engineering and Regenerative Medicine

Infrapatellar fat pad-derived MSC response to inflammation and fibrosis induces an immunomodulatory phenotype involving CD10-mediated Substance P degradation

(2019) Dimitrios Kouroupis et al.   Scientific Reports

Wnt signaling: a promising target for osteoarthritis therapy

(2019) Yudan Wang et al.   Cell Communication and Signaling

The Adipokine Network in Rheumatic Joint Diseases

(2019) Mar Carrión et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Role of Inflammation and the Immune System in the Progression of Osteoarthritis

(2019) Jennifer E. Woodell‐May et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Cell-surface markers identify tissue resident multipotential stem/stromal cell subsets in synovial intimal and sub-intimal compartments with distinct chondrogenic properties

(2019) K. Sivasubramaniyan et al.   OSTEOARTHRITIS AND CARTILAGE

Intra-articular Hyaluronan Therapy for Symptomatic Knee Osteoarthritis

(2019) Carrie Richardson et al.   RHEUMATIC DISEASE CLINICS OF NORTH AMERICA

Nomenclature clarification: synovial fibroblasts and synovial mesenchymal stem cells

(2019) Fangqi Li et al.   Stem Cell Research & Therapy

Interplay between BMPs and Reactive Oxygen Species in Cell Signaling and Pathology

(2019) Cristina Sánchez-de-Diego et al.   Biomolecules

Discovery of the Liver Hyaluronan Receptor for Endocytosis (HARE) and Its Progressive Emergence as the Multi-Ligand Scavenger Receptor Stabilin-2

(2019) Weigel   Biomolecules

Recent advances in colony stimulating factor-1 receptor/c-FMS as an emerging target for various therapeutic implications

(2018) Archana Kumari et al.   BIOMEDICINE & PHARMACOTHERAPY

Hyaluronan

(2018) Maria Grandoch et al.   CIRCULATION RESEARCH

Attenuation of inflammation and cartilage degradation by sulfasalazine-containing hyaluronic acid on osteoarthritis rat model

(2018) Sung Eun Kim et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

The infrapatellar fat pad and the synovial membrane: an anatomo-functional unit

(2018) Veronica Macchi et al.   JOURNAL OF ANATOMY

The enigmatic endosome – sorting the ins and outs of endocytic trafficking

(2018) Naava Naslavsky et al.   JOURNAL OF CELL SCIENCE

Cultures of a human synovial cell line to evaluate platelet-rich plasma and hyaluronic acid effects

(2018) E. Olivotto et al.   Journal of Tissue Engineering and Regenerative Medicine

Activated hyaluronan metabolism in the tumor matrix — Causes and consequences

(2018) Markku I. Tammi et al.   MATRIX BIOLOGY

Layilin is critical for mediating hyaluronan 35 kDa-induced intestinal epithelial tight junction protein ZO-1 in vitro and in vivo

(2018) Yeojung Kim et al.   MATRIX BIOLOGY

TSG-6: A multifunctional protein with anti-inflammatory and tissue-protective properties

(2018) Anthony J. Day et al.   MATRIX BIOLOGY

Hyaluronan in inflammatory bowel disease: Cross-linking inflammation and coagulation

(2018) Aaron C. Petrey et al.   MATRIX BIOLOGY

The pericellular hyaluronan of articular chondrocytes

(2018) Warren Knudson et al.   MATRIX BIOLOGY

Shedding light on the cell biology of extracellular vesicles

(2018) Guillaume van Niel et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Comparative advantages of infrapatellar fat pad: an emerging stem cell source for regenerative medicine

(2018) Yu Sun et al.   RHEUMATOLOGY

Regulation and function of endothelial glycocalyx layer in vascular diseases

(2018) Irina Sieve et al.   VASCULAR PHARMACOLOGY

NFκB activation in differentiating glioblastoma stem-like cells is promoted by hyaluronic acid signaling through TLR4

(2018) Eva Ferrandez et al.   Scientific Reports

The roles of inflammatory mediators and immunocytes in tendinopathy

(2018) Chenqi Tang et al.   Journal of Orthopaedic Translation

High molecular weight hyaluronan protects cartilage from degradation by inhibiting aggrecanase expression

(2018) Takashi Ohtsuki et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Hyaluronic acid-chitosan nanoparticles encoding CrmA attenuate interleukin-1β induced inflammation in synoviocytes in�vitro

(2018) Bo Qiu et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Temporal effects of cytokine treatment on lubricant synthesis and matrix metalloproteinase activity of fibroblast-like synoviocytes

(2018) Ahmad E. Abu-Hakmeh et al.   Journal of Tissue Engineering and Regenerative Medicine

Hyaluronan and Its Interactions With Immune Cells in the Healthy and Inflamed Lung

(2018) Pauline Johnson et al.   Frontiers in Immunology

Superficial cells are self-renewing chondrocyte progenitors, which form the articular cartilage in juvenile mice

(2017) Lei Li et al.   FASEB JOURNAL

New insights into autophagosome–lysosome fusion

(2017) Shuhei Nakamura et al.   JOURNAL OF CELL SCIENCE

Extracellular vesicles are integral and functional components of the extracellular matrix

(2017) Kirsi Rilla et al.   MATRIX BIOLOGY

Inhibition of Proliferation and Epithelial Mesenchymal Transition in Retinal Pigment Epithelial Cells by Heavy Chain-Hyaluronan/Pentraxin 3

(2017) Hua He et al.   Scientific Reports

TLR4-NOX2 axis regulates the phagocytosis and killing of Mycobacterium tuberculosis by macrophages

(2017) Jingzhu Lv et al.   BMC Pulmonary Medicine

Profibrotic Infrapatellar Fat Pad Remodeling Without M1 Macrophage Polarization Precedes Knee Osteoarthritis in Mice With Diet-Induced Obesity

(2017) Erika Barboza et al.   Arthritis & Rheumatology

Cytokines in tendon disease

(2017) W. Morita et al.   Bone & Joint Research

A pilot clinical trial to determine the safety and efficacy of aerosolized hyaluronan as a treatment for COPD

(2017) Jerome Cantor et al.   International Journal of Chronic Obstructive Pulmonary Disease

Rheological effects of macromolecular interactions in synovial fluid

(2016) L. Martin-Alarcon et al.   BIORHEOLOGY

Thrombin Cleavage of Inter-α-inhibitor Heavy Chain 1 Regulates Leukocyte Binding to an Inflammatory Hyaluronan Matrix

(2016) Aaron C. Petrey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

G1 Domain of Versican Regulates Hyaluronan Organization and the Phenotype of Cultured Human Dermal Fibroblasts

(2016) Mervyn J. Merrilees et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

The glycocalyx and its significance in human medicine

(2016) J. M. Tarbell et al.   JOURNAL OF INTERNAL MEDICINE

Physiochemical properties and application of hyaluronic acid: a systematic review

(2016) Natalia M Salwowska et al.   Journal of Cosmetic Dermatology

The Infrapatellar Fat Pad as a Source of Perivascular Stem Cells with Increased Chondrogenic Potential for Regenerative Medicine

(2016) Paul Hindle et al.   Stem Cells Translational Medicine

The mechanism of action for hyaluronic acid treatment in the osteoarthritic knee: a systematic review

(2015) RD Altman et al.   BMC MUSCULOSKELETAL DISORDERS

Effects of intra-articular hyaluronic acid injection on immunohistochemical characterization of joint afferents in a rat model of knee osteoarthritis

(2015) M. Ikeuchi et al.   EUROPEAN JOURNAL OF PAIN

Deletion of ADAMTS5 does not affect aggrecan or versican degradation but promotes glucose uptake and proteoglycan synthesis in murine adipose derived stromal cells

(2015) Daniel J. Gorski et al.   MATRIX BIOLOGY

Deficiency of hyaluronan synthase 1 (Has1) results in chronic joint inflammation and widespread intra-articular fibrosis in a murine model of knee joint cartilage damage

(2015) D.D. Chan et al.   OSTEOARTHRITIS AND CARTILAGE

Expression of colony-stimulating factor 1 is associated with occurrence of osteochondral change in pigmented villonodular synovitis

(2015) Takehiro Ota et al.   TUMOR BIOLOGY

High and Low Molecular Weight Hyaluronic Acid Differentially Influence Macrophage Activation

(2015) Jamie E. Rayahin et al.   ACS Biomaterials-Science & Engineering

High and Low Molecular Weight Hyaluronic Acid Differentially Influence Macrophage Activation

(2015) Jamie E. Rayahin et al.   ACS Biomaterials Science & Engineering

Hyaluronan: Biosynthesis and signaling

(2014) Davide Vigetti et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Epigenetics in extracellular matrix remodeling and hyaluronan metabolism

(2014) Davide Vigetti et al.   FEBS Journal

Heparin Prevents Intracellular Hyaluronan Synthesis and Autophagy Responses in Hyperglycemic Dividing Mesangial Cells and Activates Synthesis of an Extensive Extracellular Monocyte-adhesive Hyaluronan Matrix after Completing Cell Division

(2014) Aimin Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gene expression profiles reveal that chondrogenic progenitor cells and synovial cells are closely related

(2014) Cheng Zhou et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Versican and the control of inflammation

(2014) Thomas N. Wight et al.   MATRIX BIOLOGY

TheO-glycomap of Lubricin, a Novel Mucin Responsible for Joint Lubrication, Identified by Site-specific Glycopeptide Analysis

(2014) Liaqat Ali et al.   MOLECULAR & CELLULAR PROTEOMICS

Preventive effects of hyaluronan from deterioration of gait parameters in surgically induced mice osteoarthritic knee model

(2014) Y. Muramatsu et al.   OSTEOARTHRITIS AND CARTILAGE

Hyaluronan and RHAMM in Wound Repair and the “Cancerization” of Stromal Tissues

(2014) Cornelia Tolg et al.   Biomed Research International

Macrophage polarization and function with emphasis on the evolving roles of coordinated regulation of cellular signaling pathways

(2013) Dexi Zhou et al.   CELLULAR SIGNALLING

Extracellular vesicles: Exosomes, microvesicles, and friends

(2013) Graça Raposo et al.   JOURNAL OF CELL BIOLOGY

High molecular weight hyaluronic acid regulates osteoclast formation by inhibiting receptor activator of NF-κB ligand through Rho kinase

(2013) W. Ariyoshi et al.   OSTEOARTHRITIS AND CARTILAGE

The role of synovitis in osteoarthritis pathogenesis

(2012) Carla R. Scanzello et al.   BONE

Hyaluronan injection in murine osteoarthritis prevents TGFbeta 1-induced synovial neovascularization and fibrosis and maintains articular cartilage integrity by a CD44-dependent mechanism

(2012) Jun Li et al.   ARTHRITIS RESEARCH & THERAPY

Adamts5Deletion Blocks Murine Dermal Repair through CD44-mediated Aggrecan Accumulation and Modulation of Transforming Growth Factor β1 (TGFβ1) Signaling

(2011) Jennifer Velasco et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hyaluronan and versican in the control of human T-lymphocyte adhesion and migration

(2011) Stephen P. Evanko et al.   MATRIX BIOLOGY

Hyaluronan Signaling during Ozone-Induced Lung Injury Requires TLR4, MyD88, and TIRAP

(2011) Zhuowei Li et al.   PLoS One

Hyaluronan Inhibits Prostaglandin E2 Production via CD44 in U937 Human Macrophages

(2010) Tadashi Yasuda   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

Disulfide-bonded multimers of proteoglycan 4 (PRG4) are present in normal synovial fluids

(2009) Tannin A. Schmidt et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Microenvironmental pH Is a Key Factor for Exosome Traffic in Tumor Cells

(2009) Isabella Parolini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Innate immune system activation in osteoarthritis: is osteoarthritis a chronic wound?

(2008) Carla R Scanzello et al.   CURRENT OPINION IN RHEUMATOLOGY

Superficial zone chondrocytes in normal and osteoarthritic human articular cartilages synthesize novel truncated forms of inter-alpha-trypsin inhibitor heavy chains which are attached to a chondroitin sulfate proteoglycan other than bikunin

(2008) Y. Yoshihara et al.   OSTEOARTHRITIS AND CARTILAGE