Hyaluronan injection in murine osteoarthritis prevents TGFbeta 1-induced synovial neovascularization and fibrosis and maintains articular cartilage integrity by a CD44-dependent mechanism

Emerging evidence for endoplasmic reticulum stress in the pathogenesis of idiopathic pulmonary fibrosis

(2012) Harikrishna Tanjore et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

cAMP response element-binding (CREB) recruitment following a specific CpG demethylation leads to the elevated expression of the matrix metalloproteinase 13 in human articular chondrocytes and osteoarthritis

(2012) Catherine Bui et al.   FASEB JOURNAL

The extracellular matrix: an active or passive player in fibrosis?

(2011) Thomas N. Wight et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

A 40-month multicentre, randomised placebo-controlled study to assess the efficacy and carry-over effect of repeated intra-articular injections of hyaluronic acid in knee osteoarthritis: the AMELIA project

(2011) F. Navarro-Sarabia et al.   ANNALS OF THE RHEUMATIC DISEASES

Bone morphogenetic protein 7: A broad-spectrum growth factor with multiple target therapeutic potency

(2011) Mariëtte R. Boon et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Adamts5Deletion Blocks Murine Dermal Repair through CD44-mediated Aggrecan Accumulation and Modulation of Transforming Growth Factor β1 (TGFβ1) Signaling

(2011) Jennifer Velasco et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Severe lung fibrosis requires an invasive fibroblast phenotype regulated by hyaluronan and CD44

(2011) Yuejuan Li et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The relationship between fibrogenic TGFβ1 signaling in the joint and cartilage degradation in post-injury osteoarthritis

(2011) A. Plaas et al.   OSTEOARTHRITIS AND CARTILAGE

Global metabolic profiling of human osteoarthritic synovium

(2011) S.B. Adams et al.   OSTEOARTHRITIS AND CARTILAGE

Intraarticular injection of hyaluronan prevents cartilage erosion, periarticular fibrosis and mechanical allodynia and normalizes stance time in murine knee osteoarthritis

(2011) Anna Plaas et al.   ARTHRITIS RESEARCH & THERAPY

Aging Fibroblasts Resist Phenotypic Maturation Because of Impaired Hyaluronan-Dependent CD44/Epidermal Growth Factor Receptor Signaling

(2010) Russell M.L. Simpson et al.   AMERICAN JOURNAL OF PATHOLOGY

Synovial inflammation in patients undergoing arthroscopic meniscectomy: Molecular characterization and relationship to symptoms

(2010) Carla R. Scanzello et al.   ARTHRITIS AND RHEUMATISM

Hyaluronan inhibits matrix metalloproteinase-13 in human arthritic chondrocytes via CD44 and P38

(2010) Sohel M. Julovi et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Abnormal human chondrocyte morphology is related to increased levels of cell-associated IL-1β and disruption to pericellular collagen type VI

(2010) Dianne H. Murray et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Knockout of ADAMTS5 does not eliminate cartilage aggrecanase activity but abrogates joint fibrosis and promotes cartilage aggrecan deposition in murine osteoarthritis models

(2010) Jun Li et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Immunohistochemical characterization of reparative tissue present in human osteoarthritic tissue

(2010) Randall D. C. Barley et al.   VIRCHOWS ARCHIV

Exercise increases interleukin-10 levels both intraarticularly and peri-synovially in patients with knee osteoarthritis: a randomized controlled trial

(2010) Ida C Helmark et al.   ARTHRITIS RESEARCH & THERAPY

Modulation of TGFβ1-Dependent Myofibroblast Differentiation by Hyaluronan

(2009) Jason Webber et al.   AMERICAN JOURNAL OF PATHOLOGY

Matrix metalloproteinase 13–deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development

(2009) C. B. Little et al.   ARTHRITIS AND RHEUMATISM

Engagement of CD44 by hyaluronan suppresses TLR4 signaling and the septic response to LPS

(2009) Jun Muto et al.   MOLECULAR IMMUNOLOGY

Hyaluronan inhibits expression of ADAMTS4 (aggrecanase-1) in human osteoarthritic chondrocytes

(2008) T Yatabe et al.   ANNALS OF THE RHEUMATIC DISEASES

The effect of hyaluronic acid on IL-1β-induced chondrocyte apoptosis in a rat model of osteoarthritis

(2008) Pang-Hu Zhou et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Intra-articular Injection of Hyaluronan Diminishes Loss of Chondrocytes in a Rat Immobilized-Knee Model

(2008) Akira Ando et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE