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Title
Obesity and the Impact on Cutaneous Melanoma: Friend or Foe?
Authors
Keywords
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Journal
Cancers
Volume 12, Issue 6, Pages 1583
Publisher
MDPI AG
Online
2020-06-16
DOI
10.3390/cancers12061583
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Note: Only part of the references are listed.- Adipocyte extracellular vesicles carry enzymes and fatty acids that stimulate mitochondrial metabolism and remodeling in tumor cells
- (2020) Emily Clement et al. EMBO JOURNAL
- Update on tolerability and overall survival in COLUMBUS: landmark analysis of a randomised phase 3 trial of encorafenib plus binimetinib vs vemurafenib or encorafenib in patients with BRAF V600–mutant melanoma
- (2020) Paolo A. Ascierto et al. EUROPEAN JOURNAL OF CANCER
- Complex inter-relationship of body mass index, gender and serum creatinine on survival: exploring the obesity paradox in melanoma patients treated with checkpoint inhibition
- (2019) Girish S. Naik et al. Journal for ImmunoTherapy of Cancer
- A multicenter study of body mass index in cancer patients treated with anti-PD-1/PD-L1 immune checkpoint inhibitors: when overweight becomes favorable
- (2019) Alessio Cortellini et al. Journal for ImmunoTherapy of Cancer
- A lipase-independent pathway of lipid release and immune modulation by adipocytes
- (2019) Stephen E. Flaherty et al. SCIENCE
- Omics analysis of oxysterols to better understand their pathophysiological role
- (2019) Barbara Sottero et al. FREE RADICAL BIOLOGY AND MEDICINE
- Adipocyte and lipid metabolism in cancer drug resistance
- (2019) Yihai Cao JOURNAL OF CLINICAL INVESTIGATION
- Blockade of TGF-β signaling to enhance the antitumor response is accompanied by dysregulation of the functional activity of CD4+CD25+Foxp3+ and CD4+CD25−Foxp3+ T cells
- (2019) Magdalena J. Polanczyk et al. Journal of Translational Medicine
- Five-Year Outcomes with Dabrafenib plus Trametinib in Metastatic Melanoma
- (2019) Caroline Robert et al. NEW ENGLAND JOURNAL OF MEDICINE
- Cancer-associated adipocytes: key players in breast cancer progression
- (2019) Qi Wu et al. Journal of Hematology & Oncology
- Five-Year Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma
- (2019) James Larkin et al. NEW ENGLAND JOURNAL OF MEDICINE
- The complex relationship between body mass index and response to immune checkpoint inhibition in metastatic melanoma patients
- (2019) Douglas Donnelly et al. Journal for ImmunoTherapy of Cancer
- Liver X Receptor Agonism Sensitizes a Subset of Hepatocellular Carcinoma to Sorafenib by Dual-Inhibiting MET and EGFR
- (2019) Weiqing Shao et al. NEOPLASIA
- Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming
- (2018) Anette Christ et al. CELL
- Toward Minimal Residual Disease-Directed Therapy in Melanoma
- (2018) Florian Rambow et al. CELL
- Frontline Science: High fat diet and leptin promote tumor progression by inducing myeloid-derived suppressor cells
- (2018) Virginia K. Clements et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Association of body-mass index and outcomes in patients with metastatic melanoma treated with targeted therapy, immunotherapy, or chemotherapy: a retrospective, multicohort analysis
- (2018) Jennifer L McQuade et al. LANCET ONCOLOGY
- The microbiome in cancer immunotherapy: Diagnostic tools and therapeutic strategies
- (2018) Laurence Zitvogel et al. SCIENCE
- Adipocyte-Derived Lipids Mediate Melanoma Progression via FATP Proteins
- (2018) Maomao Zhang et al. Cancer Discovery
- Activation of G protein-coupled estrogen receptor signaling inhibits melanoma and improves response to immune checkpoint blockade
- (2018) Christopher A Natale et al. eLife
- Obesity, Fat Mass and Immune System: Role for Leptin
- (2018) Vera Francisco et al. Frontiers in Physiology
- Cutting Edge: Elevated Leptin during Diet-Induced Obesity Reduces the Efficacy of Tumor Immunotherapy
- (2018) Katherine A. Murphy et al. JOURNAL OF IMMUNOLOGY
- Suppression of insulin feedback enhances the efficacy of PI3K inhibitors
- (2018) Benjamin D. Hopkins et al. NATURE
- Body mass index may predict the response to ipilimumab in metastatic melanoma: An observational multi-centre study
- (2018) Georg Richtig et al. PLoS One
- Fundamental Mechanisms of Immune Checkpoint Blockade Therapy
- (2018) Spencer C. Wei et al. Cancer Discovery
- Paradoxical effects of obesity on T cell function during tumor progression and PD-1 checkpoint blockade
- (2018) Ziming Wang et al. NATURE MEDICINE
- MAPK pathway in melanoma part II—secondary and adaptive resistance mechanisms to BRAF inhibition
- (2017) Teresa Amaral et al. EUROPEAN JOURNAL OF CANCER
- Association between Body Mass Index, C-Reactive Protein Levels, and Melanoma Patient Outcomes
- (2017) Shenying Fang et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Adapting to obesity with adipose tissue inflammation
- (2017) Shannon M. Reilly et al. Nature Reviews Endocrinology
- Overall Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma
- (2017) Jedd D. Wolchok et al. NEW ENGLAND JOURNAL OF MEDICINE
- Estrogens in Male Physiology
- (2017) Paul S. Cooke et al. PHYSIOLOGICAL REVIEWS
- Metabolic strategies of melanoma cells: Mechanisms, interactions with the tumor microenvironment, and therapeutic implications
- (2017) Grant M. Fischer et al. Pigment Cell & Melanoma Research
- Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients
- (2017) V. Gopalakrishnan et al. SCIENCE
- IFN-γ is required for cytotoxic T cell-dependent cancer genome immunoediting
- (2017) Kazuyoshi Takeda et al. Nature Communications
- Melanoma Therapeutic Strategies that Select against Resistance by Exploiting MYC-Driven Evolutionary Convergence
- (2017) Katherine R. Singleton et al. Cell Reports
- Adipocyte Exosomes Promote Melanoma Aggressiveness through Fatty Acid Oxidation: A Novel Mechanism Linking Obesity and Cancer
- (2016) Ikrame Lazar et al. CANCER RESEARCH
- Genomic and Transcriptomic Features of Response to Anti-PD-1 Therapy in Metastatic Melanoma
- (2016) Willy Hugo et al. CELL
- Dual Faces of IFN in Cancer Progression: A Role of PD-L1 Induction in the Determination of Pro- and Antitumor Immunity
- (2016) M. Mandai et al. CLINICAL CANCER RESEARCH
- Macrophage Proliferation Sustains Adipose Tissue Inflammation in Formerly Obese Mice
- (2016) Brian F. Zamarron et al. DIABETES
- Bioenergetic Insufficiencies Due to Metabolic Alterations Regulated by the Inhibitory Receptor PD-1 Are an Early Driver of CD8 + T Cell Exhaustion
- (2016) Bertram Bengsch et al. IMMUNITY
- Targeting mitochondrial biogenesis to overcome drug resistance to MAPK inhibitors
- (2016) Gao Zhang et al. JOURNAL OF CLINICAL INVESTIGATION
- Cobimetinib combined with vemurafenib in advanced BRAFV600-mutant melanoma (coBRIM): updated efficacy results from a randomised, double-blind, phase 3 trial
- (2016) Paolo A Ascierto et al. LANCET ONCOLOGY
- Elevated Serum Leptin Levels are Associated With an Increased Risk of Sentinel Lymph Node Metastasis in Cutaneous Melanoma
- (2016) Junna Oba et al. MEDICINE
- Targeting metastasis-initiating cells through the fatty acid receptor CD36
- (2016) Gloria Pascual et al. NATURE
- Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patients
- (2016) Alena Gros et al. NATURE MEDICINE
- Body Fatness and Cancer — Viewpoint of the IARC Working Group
- (2016) Béatrice Lauby-Secretan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Gut microbiota, obesity and diabetes
- (2016) Elaine Patterson et al. POSTGRADUATE MEDICAL JOURNAL
- Density of immunogenic antigens does not explain the presence or absence of the T-cell–inflamed tumor microenvironment in melanoma
- (2016) Stefani Spranger et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- IGF-1 contributes to the expansion of melanoma-initiating cells through an epithelial-mesenchymal transition process
- (2016) Vincent Le Coz et al. Oncotarget
- Sex steroids regulate skin pigmentation through nonclassical membrane-bound receptors
- (2016) Christopher A Natale et al. eLife
- Obesity is associated with changes in oxysterol metabolism and levels in mice liver, hypothalamus, adipose tissue and plasma
- (2016) Owein Guillemot-Legris et al. Scientific Reports
- Genetic alterations in fatty acid transport and metabolism genes are associated with metastatic progression and poor prognosis of human cancers
- (2016) Aritro Nath et al. Scientific Reports
- Multiple Structural and Epigenetic Defects in the Human Leukocyte Antigen Class I Antigen Presentation Pathway in a Recurrent Metastatic Melanoma Following Immunotherapy
- (2015) Chien-Chung Chang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2015) Hee-Bum Kang et al. MOLECULAR CELL
- Genomic correlates of response to CTLA-4 blockade in metastatic melanoma
- (2015) E. M. Van Allen et al. SCIENCE
- MAPK pathway inhibition in melanoma: resistance three ways: Figure 1
- (2014) Claudia Wellbrock BIOCHEMICAL SOCIETY TRANSACTIONS
- Inhibition of mTORC1/2 Overcomes Resistance to MAPK Pathway Inhibitors Mediated by PGC1 and Oxidative Phosphorylation in Melanoma
- (2014) Y. N. V. Gopal et al. CANCER RESEARCH
- Broad-Spectrum Therapeutic Suppression of Metastatic Melanoma through Nuclear Hormone Receptor Activation
- (2014) Nora Pencheva et al. CELL
- Adipocytes Contribute to Resistance of Human Melanoma Cells to Chemotherapy and Targeted Therapy
- (2014) M. Chi et al. CURRENT MEDICINAL CHEMISTRY
- Mutational signatures: the patterns of somatic mutations hidden in cancer genomes
- (2014) Ludmil B Alexandrov et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- New insights into cancer immunoediting and its three component phases—elimination, equilibrium and escape
- (2014) Deepak Mittal et al. CURRENT OPINION IN IMMUNOLOGY
- High-fat diet-induced obesity increases lymphangiogenesis and lymph node metastasis in the B16F10 melanoma allograft model: Roles of adipocytes and M2-macrophages
- (2014) Jae In Jung et al. INTERNATIONAL JOURNAL OF CANCER
- Subcutaneous Adipocytes Promote Melanoma Cell Growth by Activating the Akt Signaling Pathway
- (2014) Hiu Yee Kwan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Role of obesity on the thickness of primary cutaneous melanoma
- (2014) F. Skowron et al. JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
- Obesity induced rapid melanoma progression is reversed by orlistat treatment and dietary intervention: Role of adipokines
- (2014) Parmanand Malvi et al. Molecular Oncology
- Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens
- (2014) Matthew M. Gubin et al. NATURE
- The mechanism of action of BCG therapy for bladder cancer—a current perspective
- (2014) Gil Redelman-Sidi et al. Nature Reviews Urology
- The Anti-Tumor Activity of a Neutralizing Nanobody Targeting Leptin Receptor in a Mouse Model of Melanoma
- (2014) Travis McMurphy et al. PLoS One
- Macrophage colony-stimulating factor and cancer: a review
- (2014) S. Chockalingam et al. TUMOR BIOLOGY
- Response of BRAF-Mutant Melanoma to BRAF Inhibition Is Mediated by a Network of Transcriptional Regulators of Glycolysis
- (2014) T. J. Parmenter et al. Cancer Discovery
- Autophagy Controls BCG-Induced Trained Immunity and the Response to Intravesical BCG Therapy for Bladder Cancer
- (2014) Kathrin Buffen et al. PLoS Pathogens
- Oncogenic BRAF Regulates Oxidative Metabolism via PGC1α and MITF
- (2013) Rizwan Haq et al. CANCER CELL
- Lower Skin Cancer Risk in Women with Higher Body Mass Index: The Women's Health Initiative Observational Study
- (2013) J. Y. Tang et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- Angiogenesis and Vascular Functions in Modulation of Obesity, Adipose Metabolism, and Insulin Sensitivity
- (2013) Yihai Cao Cell Metabolism
- BRAF Inhibition Is Associated with Enhanced Melanoma Antigen Expression and a More Favorable Tumor Microenvironment in Patients with Metastatic Melanoma
- (2013) D. T. Frederick et al. CLINICAL CANCER RESEARCH
- Sex Is an Independent Prognostic Indicator for Survival and Relapse/Progression-Free Survival in Metastasized Stage III to IV Melanoma: A Pooled Analysis of Five European Organisation for Research and Treatment of Cancer Randomized Controlled Trials
- (2013) Arjen Joosse et al. JOURNAL OF CLINICAL ONCOLOGY
- Acquired Resistance and Clonal Evolution in Melanoma during BRAF Inhibitor Therapy
- (2013) H. Shi et al. Cancer Discovery
- Inflamed tumor-associated adipose tissue is a depot for macrophages that stimulate tumor growth and angiogenesis
- (2012) Marek Wagner et al. ANGIOGENESIS
- Convergent Multi-miRNA Targeting of ApoE Drives LRP1/LRP8-Dependent Melanoma Metastasis and Angiogenesis
- (2012) Nora Pencheva et al. CELL
- A Landscape of Driver Mutations in Melanoma
- (2012) Eran Hodis et al. CELL
- Obesity and risk of malignant melanoma: A meta-analysis of cohort and case–control studies
- (2012) Theodoros N. Sergentanis et al. EUROPEAN JOURNAL OF CANCER
- Superior Outcome of Women With Stage I/II Cutaneous Melanoma: Pooled Analysis of Four European Organisation for Research and Treatment of Cancer Phase III Trials
- (2012) Arjen Joosse et al. JOURNAL OF CLINICAL ONCOLOGY
- Marked, Homogeneous, and Early [18F]Fluorodeoxyglucose–Positron Emission Tomography Responses to Vemurafenib in BRAF-Mutant Advanced Melanoma
- (2012) Grant A. McArthur et al. JOURNAL OF CLINICAL ONCOLOGY
- Diet-Induced Obesity Alters Dendritic Cell Function in the Presence and Absence of Tumor Growth
- (2012) B. R. James et al. JOURNAL OF IMMUNOLOGY
- Trained Immunity: A Memory for Innate Host Defense
- (2011) Mihai G. Netea et al. Cell Host & Microbe
- Selective BRAF Inhibitors Induce Marked T-cell Infiltration into Human Metastatic Melanoma
- (2011) James S. Wilmott et al. CLINICAL CANCER RESEARCH
- Role of bacillus Calmette–Guérin in the treatment of advanced melanoma
- (2011) John H Stewart et al. Expert Review of Anticancer Therapy
- Diet-induced obesity increases melanoma progression: Involvement of Cav-1 and FASN
- (2011) Vimal Pandey et al. INTERNATIONAL JOURNAL OF CANCER
- Cancer Immunoediting: Integrating Immunity's Roles in Cancer Suppression and Promotion
- (2011) R. D. Schreiber et al. SCIENCE
- Inhibition of fatty acid synthase in melanoma cells activates the intrinsic pathway of apoptosis
- (2010) Karina G Zecchin et al. LABORATORY INVESTIGATION
- Promotion of melanoma growth by the metabolic hormone leptin
- (2010) Ellerhorst ONCOLOGY REPORTS
- Obesity accelerates thymic aging
- (2009) H. Yang et al. BLOOD
- Enhancing CD8 T-cell memory by modulating fatty acid metabolism
- (2009) Erika L. Pearce et al. NATURE
- Are Natural Killer Cells Protecting the Metabolically Healthy Obese Patient?
- (2009) Lydia A. Lynch et al. Obesity
- Risk of lymphoma and leukaemia after bacille Calmette-Guérin and smallpox vaccination: A Danish case-cohort study
- (2009) Marie Villumsen et al. VACCINE
- Fatty acid synthase inhibition with Orlistat promotes apoptosis and reduces cell growth and lymph node metastasis in a mouse melanoma model
- (2008) Marco A. Carvalho et al. INTERNATIONAL JOURNAL OF CANCER
- Obesity and cancer: Pathophysiological and biological mechanisms
- (2008) Andrew G. Renehan et al. ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY
- Melanoma risk in association with serum leptin levels and lifestyle parameters: a case-control study
- (2007) H. Gogas et al. ANNALS OF ONCOLOGY
- IGF1 Promotes Resistance to Apoptosis in Melanoma Cells through an Increased Expression of BCL2, BCL-X(L), and Survivin
- (2007) Caroline Hilmi et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
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