IFN-γ is required for cytotoxic T cell-dependent cancer genome immunoediting

Tumor Interferon Signaling Regulates a Multigenic Resistance Program to Immune Checkpoint Blockade

(2016) Joseph L. Benci et al.   CELL

Preventing tumor escape by targeting a post-proteasomal trimming independent epitope

(2016) Ana Textor et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns

(2016) Faiyaz Notta et al.   NATURE

A saltationist theory of cancer evolution

(2016) Florian Markowetz   NATURE GENETICS

Punctuated copy number evolution and clonal stasis in triple-negative breast cancer

(2016) Ruli Gao et al.   NATURE GENETICS

Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma

(2016) Jesse M. Zaretsky et al.   NEW ENGLAND JOURNAL OF MEDICINE

Molecular and Genetic Properties of Tumors Associated with Local Immune Cytolytic Activity

(2015) Michael S. Rooney et al.   CELL

Eradication of Large Solid Tumors by Gene Therapy with a T-Cell Receptor Targeting a Single Cancer-Specific Point Mutation

(2015) M. Leisegang et al.   CLINICAL CANCER RESEARCH

APOBEC Enzymes: Mutagenic Fuel for Cancer Evolution and Heterogeneity

(2015) C. Swanton et al.   Cancer Discovery

T Cell Intrinsic USP15 Deficiency Promotes Excessive IFN-γ Production and an Immunosuppressive Tumor Microenvironment in MCA-Induced Fibrosarcoma

(2015) Qiang Zou et al.   Cell Reports

Genetic and Clonal Dissection of Murine Small Cell Lung Carcinoma Progression by Genome Sequencing

(2014) David G. McFadden et al.   CELL

Clonal evolution in breast cancer revealed by single nucleus genome sequencing

(2014) Yong Wang et al.   NATURE

The mutational landscapes of genetic and chemical models of Kras-driven lung cancer

(2014) Peter M. K. Westcott et al.   NATURE

Tissue factor expression provokes escape from tumor dormancy and leads to genomic alterations

(2014) Nathalie Magnus et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exomics and immunogenics

(2014) Stéphane Champiat et al.   OncoImmunology

Relapse or Eradication of Cancer Is Predicted by Peptide-Major Histocompatibility Complex Affinity

(2013) Boris Engels et al.   CANCER CELL

Cytotoxic T cells induce proliferation of chronic myeloid leukemia stem cells by secreting interferon-γ

(2013) Christian Schürch et al.   JOURNAL OF EXPERIMENTAL MEDICINE

T-helper-1-cell cytokines drive cancer into senescence

(2013) Heidi Braumüller et al.   NATURE

Pan-cancer patterns of somatic copy number alteration

(2013) Travis I Zack et al.   NATURE GENETICS

Detecting and targeting tumor relapse by its resistance to innate effectors at early recurrence

(2013) Timothy Kottke et al.   NATURE MEDICINE

IFN-  and Lipopolysaccharide Upregulate APOBEC3 mRNA through Different Signaling Pathways

(2012) H. V. Mehta et al.   JOURNAL OF IMMUNOLOGY

Melanomas resist T-cell therapy through inflammation-induced reversible dedifferentiation

(2012) Jennifer Landsberg et al.   NATURE

Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting

(2012) Hirokazu Matsushita et al.   NATURE

Expression of tumour-specific antigens underlies cancer immunoediting

(2012) Michel DuPage et al.   NATURE

Inactivation of ATM/ATR DNA Damage Checkpoint Promotes Androgen Induced Chromosomal Instability in Prostate Epithelial Cells

(2012) Yung-Tuen Chiu et al.   PLoS One

Colocalization of Inflammatory Response with B7-H1 Expression in Human Melanocytic Lesions Supports an Adaptive Resistance Mechanism of Immune Escape

(2012) J. M. Taube et al.   Science Translational Medicine

Targeting ATR in vivo using the novel inhibitor VE-822 results in selective sensitization of pancreatic tumors to radiation

(2012) E Fokas et al.   Cell Death & Disease

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

The Two Faces of Interferon-  in Cancer

(2011) M. R. Zaidi et al.   CLINICAL CANCER RESEARCH

IFN-γ production by lung NK cells is critical for the natural resistance to pulmonary metastasis of B16 melanoma in mice

(2011) Kazuyoshi Takeda et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Interferon-γ links ultraviolet radiation to melanomagenesis in mice

(2011) M. Raza Zaidi et al.   NATURE

Early-stage formation of an epigenetic field defect in a mouse colitis model and non-essential roles of T- and B-cells in DNA methylation induction

(2011) M Katsurano et al.   ONCOGENE

Cancer Immunoediting: Integrating Immunity's Roles in Cancer Suppression and Promotion

(2011) R. D. Schreiber et al.   SCIENCE

Stem Cell-Like Properties of the Endometrial Side Population: Implication in Endometrial Regeneration

(2010) Hirotaka Masuda et al.   PLoS One