Screening and Identification of Therapeutic Targets for Pulmonary Arterial Hypertension Through Microarray Technology

Epigenetic Inheritance Underlying Pulmonary Arterial Hypertension

(2019) Claudio Napoli et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Role for polo-like kinase 4 in mediation of cytokinesis

(2019) Michael F. Press et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Self-organization of Plk4 regulates symmetry breaking in centriole duplication

(2019) Shohei Yamamoto et al.   Nature Communications

Phase separation of Polo-like kinase 4 by autoactivation and clustering drives centriole biogenesis

(2019) Jung-Eun Park et al.   Nature Communications

Meta-analysis of blood genome-wide expression profiling studies in pulmonary arterial hypertension

(2019) Jason M. Elinoff et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Selenoprotein P Promotes the Development of Pulmonary Arterial Hypertension: A Possible Novel Therapeutic Target

(2018) Nobuhiro Kikuchi et al.   CIRCULATION

NMDA-Type Glutamate Receptor Activation Promotes Vascular Remodeling and Pulmonary Arterial Hypertension

(2018) Sébastien J. Dumas et al.   CIRCULATION

Advances in Transcriptomics

(2018) Robert C. Wirka et al.   CIRCULATION RESEARCH

Fast and furious . . . or not, Plk4 dictates the pace

(2018) Simon Gemble et al.   JOURNAL OF CELL BIOLOGY

Polo-like kinase 4 inhibition produces polyploidy and apoptotic death of lung cancers

(2018) Masanori Kawakami et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PPARγ agonist pioglitazone reverses pulmonary hypertension and prevents right heart failure via fatty acid oxidation

(2018) Ekaterina Legchenko et al.   Science Translational Medicine

Direct binding of CEP85 to STIL ensures robust PLK4 activation and efficient centriole assembly

(2018) Yi Liu et al.   Nature Communications

Fragile Histidine Triad (FHIT), a Novel Modifier Gene in Pulmonary Arterial Hypertension

(2018) Svenja Dannewitz Prosseda et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

New and Emerging Therapies for Pulmonary Arterial Hypertension

(2018) Edda Spiekerkoetter et al.   Annual Review of Medicine

Pathology and pathobiology of pulmonary hypertension: state of the art and research perspectives

(2018) Marc Humbert et al.   EUROPEAN RESPIRATORY JOURNAL

Genetics and genomics of pulmonary arterial hypertension

(2018) Nicholas W. Morrell et al.   EUROPEAN RESPIRATORY JOURNAL

Haemodynamic definitions and updated clinical classification of pulmonary hypertension

(2018) Gérald Simonneau et al.   EUROPEAN RESPIRATORY JOURNAL

Integrated bioinformatic analysis reveals YWHAB as a novel diagnostic biomarker for idiopathic pulmonary arterial hypertension

(2018) Tao Wang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The Gene Ontology Resource: 20 years and still GOing strong

(2018)   NUCLEIC ACIDS RESEARCH

PLK4: a link between centriole biogenesis and cancer

(2017) Radhika Radha Maniswami et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Epidemiology and treatment of pulmonary arterial hypertension

(2017) Edmund M. T. Lau et al.   Nature Reviews Cardiology

Plk4 Promotes Cancer Invasion and Metastasis through Arp2/3 Complex Regulation of the Actin Cytoskeleton

(2016) Karineh Kazazian et al.   CANCER RESEARCH

Microarray analysis in pulmonary hypertension

(2016) Julia Hoffmann et al.   EUROPEAN RESPIRATORY JOURNAL

The STRING database in 2017: quality-controlled protein–protein association networks, made broadly accessible

(2016) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

S84 Identification of MIR-124a as a major regulator of enhanced endothelial cell glycolysis in pulmonary arterial hypertension

(2016) P Caruso et al.   THORAX

Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types

(2016) S. P. Kar et al.   Cancer Discovery

Condensin Smc2-Smc4 Dimers Are Flexible and Dynamic

(2016) Jorine M. Eeftens et al.   Cell Reports

Adaptation and Remodelling of the Pulmonary Circulation in Pulmonary Hypertension

(2015) Mylène Vaillancourt et al.   CANADIAN JOURNAL OF CARDIOLOGY

Five-Year Outcomes of Patients Enrolled in the REVEAL Registry

(2015) Harrison W. Farber et al.   CHEST

Binding of STIL to Plk4 activates kinase activity to promote centriole assembly

(2015) Tyler C. Moyer et al.   JOURNAL OF CELL BIOLOGY

KEGG as a reference resource for gene and protein annotation

(2015) Minoru Kanehisa et al.   NUCLEIC ACIDS RESEARCH

The p53-p21-DREAM-CDE/CHR pathway regulates G2/M cell cycle genes

(2015) Martin Fischer et al.   NUCLEIC ACIDS RESEARCH

Reversible centriole depletion with an inhibitor of Polo-like kinase 4

(2015) Y. L. Wong et al.   SCIENCE

Functional Characterization of CFI-400945, a Polo-like Kinase 4 Inhibitor, as a Potential Anticancer Agent

(2014) Jacqueline M. Mason et al.   CANCER CELL

Oncogene-like induction of cellular invasion from centrosome amplification

(2014) Susana A. Godinho et al.   NATURE

Changing Demographics, Epidemiology, and Survival of Incident Pulmonary Arterial Hypertension

(2012) Yi Ling et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

An Evaluation of Long-term Survival From Time of Diagnosis in Pulmonary Arterial Hypertension From the REVEAL Registry

(2012) Raymond L. Benza et al.   CHEST

Human SMC2 Protein, a Core Subunit of Human Condensin Complex, Is a Novel Transcriptional Target of the WNT Signaling Pathway and a New Therapeutic Target

(2012) Verónica Dávalos et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NCBI GEO: archive for functional genomics data sets—update

(2012) Tanya Barrett et al.   NUCLEIC ACIDS RESEARCH