Combining high throughput and high quality for cryo-electron microscopy data collection

The structure of the cohesin ATPase elucidates the mechanism of SMC–kleisin ring opening

(2020) Kyle W. Muir et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A Structure-Based Model for the Complete Transcription Cycle of Influenza Polymerase

(2020) Joanna M. Wandzik et al.   CELL

Cryo-EM structure of the Hedgehog release protein Dispatched

(2020) Fabien Cannac et al.   Science Advances

Challenges and opportunities in cryo-EM single-particle analysis

(2019) Dmitry Lyumkis   JOURNAL OF BIOLOGICAL CHEMISTRY

The structure of a membrane adenylyl cyclase bound to an activated stimulatory G protein

(2019) Chao Qi et al.   SCIENCE

Advances in Single Particle Analysis Data Acquisition

(2019) Stan Konings et al.   MICROSCOPY AND MICROANALYSIS

Structural basis of sterol recognition by human hedgehog receptor PTCH1

(2019) Chao Qi et al.   Science Advances

Toward high-resolution in situ structural biology with cryo-electron tomography and subtomogram averaging

(2019) Florian KM Schur   CURRENT OPINION IN STRUCTURAL BIOLOGY

Approaches to altering particle distributions in cryo-electron microscopy sample preparation

(2018) Ieva Drulyte et al.   Acta Crystallographica Section D-Structural Biology

High-resolution structures of HIV-1 Gag cleavage mutants determine structural switch for virus maturation

(2018) Simone Mattei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sub-2 Å Ewald curvature corrected structure of an AAV2 capsid variant

(2018) Yong Zi Tan et al.   Nature Communications

Cryo-EM structures of human STEAP4 reveal mechanism of iron(III) reduction

(2018) Wout Oosterheert et al.   Nature Communications

Subtomogram averaging of COPII assemblies reveals how coat organization dictates membrane shape

(2018) Joshua Hutchings et al.   Nature Communications

New tools for automated high-resolution cryo-EM structure determination in RELION-3

(2018) Jasenko Zivanov et al.   eLife

cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination

(2017) Ali Punjani et al.   NATURE METHODS

An atomic model of HIV-1 capsid-SP1 reveals structures regulating assembly and maturation

(2016) Florian K. M. Schur et al.   SCIENCE

The Resolution Revolution

(2014) W. Kuhlbrandt   SCIENCE

Precise beam-tilt alignment and collimation are required to minimize the phase error associated with coma in high-resolution cryo-EM

(2010) Robert M. Glaeser et al.   JOURNAL OF STRUCTURAL BIOLOGY

A test-bed for optimizing high-resolution single particle reconstructions

(2008) Scott M. Stagg et al.   JOURNAL OF STRUCTURAL BIOLOGY