Translating Scientific Advances in the AOP Framework to Decision Making for Nanomaterials

NanoSolveIT Project: Driving Nanoinformatics research to develop innovative and integrated tools for in silico nanosafety assessment

(2020) Antreas Afantitis et al.   Computational and Structural Biotechnology Journal

Adverse outcome pathways as a tool for the design of testing strategies to support the safety assessment of emerging advanced materials at the nanoscale

(2020) Sabina Halappanavar et al.   Particle and Fibre Toxicology

Acute Phase Response as a Biological Mechanism‐of‐Action of (Nano)particle‐Induced Cardiovascular Disease

(2020) Niels Hadrup et al.   Small

21st Century Tools for Nanotoxicology: Transcriptomic Biomarker Panel and Precision‐Cut Lung Slice Organ Mimic System for the Assessment of Nanomaterial‐Induced Lung Fibrosis

(2020) Luna Rahman et al.   Small

Risk Analysis of Cellulose Nanomaterials by Inhalation: Current State of Science

(2019) James Ede et al.   Nanomaterials

A Definition and Categorization System for Advanced Materials: The Foundation for Risk‐Informed Environmental Health and Safety Testing

(2019) Alan Kennedy et al.   RISK ANALYSIS

Pulmonary toxicity of two different multi-walled carbon nanotubes in rat: Comparison between intratracheal instillation and inhalation exposure

(2019) Laurent Gaté et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Commentary: the chronic inhalation study in rats for assessing lung cancer risk may be better than its reputation

(2019) Anne T. Saber et al.   Particle and Fibre Toxicology

Updating traditional regulatory tests for use with novel materials: Nanomaterial toxicity testing with Daphnia magna

(2019) Fatima Nasser et al.   SAFETY SCIENCE

Multimodal Precision Imaging of Pulmonary Nanoparticle Delivery in Mice: Dynamics of Application, Spatial Distribution, and Dosimetry

(2019) Lin Yang et al.   Small

Effects of physicochemical properties of TiO2 nanomaterials for pulmonary inflammation, acute phase response and alveolar proteinosis in intratracheally exposed mice

(2019) Pernille Høgh Danielsen et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Advanced tools for the safety assessment of nanomaterials

(2018) Bengt Fadeel et al.   Nature Nanotechnology

Editorial: dose-dependent ZnO particle-induced acute phase response in humans warrants re-evaluation of occupational exposure limits for metal oxides

(2018) Ulla Vogel et al.   Particle and Fibre Toxicology

Harvesting the promise of AOPs: An assessment and recommendations

(2018) Annamaria Carusi et al.   SCIENCE OF THE TOTAL ENVIRONMENT

The uncertainty with nanosafety: Validity and reliability of published data

(2018) Harald F. Krug   COLLOIDS AND SURFACES B-BIOINTERFACES

Insights into possibilities for grouping and read-across for nanomaterials in EU chemicals legislation

(2018) A. Mech et al.   Nanotoxicology

Minimum information reporting in bio–nano experimental literature

(2018) Matthew Faria et al.   Nature Nanotechnology

Advancing the adverse outcome pathway framework-An international horizon scanning approach

(2017) Carlie A. LaLone et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Stat-6 signaling pathway and not Interleukin-1 mediates multi-walled carbon nanotube-induced lung fibrosis in mice: insights from an adverse outcome pathway framework

(2017) Jake Nikota et al.   Particle and Fibre Toxicology

Aligning nanotoxicology with the 3Rs: What is needed to realise the short, medium and long-term opportunities?

(2017) Natalie Burden et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Nano-risk Science: application of toxicogenomics in an adverse outcome pathway framework for risk assessment of multi-walled carbon nanotubes

(2015) Sarah Labib et al.   Particle and Fibre Toxicology

Lung carcinogenicity of inhaled multi-walled carbon nanotube in rats

(2015) Tatsuya Kasai et al.   Particle and Fibre Toxicology

Advanced computational modeling for in vitro nanomaterial dosimetry

(2015) Glen M. DeLoid et al.   Particle and Fibre Toxicology

Towards sensible toxicity testing for nanomaterials: proposal for the specification of test design

(2015) Annegret Potthoff et al.   SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS

Defining Molecular Initiating Events in the Adverse Outcome Pathway Framework for Risk Assessment

(2014) Timothy E. H. Allen et al.   CHEMICAL RESEARCH IN TOXICOLOGY

ITS-NANO - Prioritising nanosafety research to develop a stakeholder driven intelligent testing strategy

(2014) Vicki Stone et al.   Particle and Fibre Toxicology

Adverse Outcome Pathway (AOP) Development I: Strategies and Principles

(2014) Daniel L. Villeneuve et al.   TOXICOLOGICAL SCIENCES

Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment

(2010) Gerald T. Ankley et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Development ofin vitrosystems for nanotoxicology: methodological considerations

(2009) Vicki Stone et al.   CRITICAL REVIEWS IN TOXICOLOGY