Baicalein Attenuates Pyroptosis and Endoplasmic Reticulum Stress Following Spinal Cord Ischemia-Reperfusion Injury via Autophagy Enhancement

Salidroside Decreases Atherosclerosis Plaque Formation via Inhibiting Endothelial Cell Pyroptosis

(2020) Sha-Sha Xing et al.   INFLAMMATION

Mechanisms and Therapeutic Regulation of Pyroptosis in Inflammatory Diseases and Cancer

(2020) Zhaodi Zheng et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Baicalin attenuates hepatic injury in non-alcoholic steatohepatitis cell model by suppressing inflammasome-dependent GSDMD-mediated cell pyroptosis

(2020) Huilian Shi et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Oxidative Insults and Mitochondrial DNA Mutation Promote Enhanced Autophagy and Mitophagy Compromising Cell Viability in Pluripotent Cell Model of Mitochondrial Disease

(2019) Dar-Shong Lin et al.   Cells

Lipopolysaccharide (LPS) Aggravates High Glucose- and Hypoxia/Reoxygenation-Induced Injury through Activating ROS-Dependent NLRP3 Inflammasome-Mediated Pyroptosis in H9C2 Cardiomyocytes

(2019) Zhen Qiu et al.   Journal of Diabetes Research

Hyperglycemia aggravates spinal cord injury through endoplasmic reticulum stress mediated neuronal apoptosis, gliosis and activation

(2019) Zhirong Chen et al.   BIOMEDICINE & PHARMACOTHERAPY

Autophagy protects HUVECs against ER stress-mediated apoptosis under simulated microgravity

(2019) Cheng-Fei Li et al.   APOPTOSIS

Neuroprotective effects of minocycline and progesterone on white matter injury after focal cerebral ischemia

(2019) Heba Faheem et al.   JOURNAL OF CLINICAL NEUROSCIENCE

The Pathway of Let-7a-1/2-3p and HMGB1 Mediated Dexmedetomidine Inhibiting Microglia Activation in Spinal Cord Ischemia-Reperfusion Injury Mice

(2019) Ha sen ta na et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

PINK1-parkin pathway of mitophagy protects against contrast-induced acute kidney injury via decreasing mitochondrial ROS and NLRP3 inflammasome activation

(2019) Qisheng Lin et al.   Redox Biology

Dexmedetomidine attenuates neuronal injury after spinal cord ischaemia‐reperfusion injury by targeting the CNPY2‐endoplasmic reticulum stress signalling

(2019) Lina Zhao et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Exosomes Mediate Hippocampal and Cortical Neuronal Injury Induced by Hepatic Ischemia-Reperfusion Injury through Activating Pyroptosis in Rats

(2019) Limei Zhang et al.   Oxidative Medicine and Cellular Longevity

PRMT1 suppresses ATF4-mediated endoplasmic reticulum response in cardiomyocytes

(2019) Myong-Ho Jeong et al.   Cell Death & Disease

Pyroptosis is a critical inflammatory pathway in the placenta from early onset preeclampsia and in human trophoblasts exposed to hypoxia and endoplasmic reticulum stressors

(2019) Shi-Bin Cheng et al.   Cell Death & Disease

Triggering of Autophagy by Baicalein in Response to Apoptosis after Spinal Cord Injury: Possible Involvement of the PI3K Activation

(2018) Yuanlong Li et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Pioglitazone Confers Neuroprotection Against Ischemia-Induced Pyroptosis due to its Inhibitory Effects on HMGB-1/RAGE and Rac1/ROS Pathway by Activating PPAR-ɤ

(2018) Pingping Xia et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Chloroquine Promotes the Recovery of Acute Spinal Cord Injury by Inhibiting Autophagy-Associated Inflammation and Endoplasmic Reticulum Stress

(2018) Fenzan Wu et al.   JOURNAL OF NEUROTRAUMA

An overview of protective strategies against ischemia/reperfusion injury: The role of hyperbaric oxygen preconditioning

(2018) Ciprian Hentia et al.   Brain and Behavior

Celastrol inhibits microglial pyroptosis and attenuates inflammatory reaction in acute spinal cord injury rats

(2018) Wangying Dai et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Rapamycin Enhances Mitophagy and Attenuates Apoptosis After Spinal Ischemia-Reperfusion Injury

(2018) Qiang Li et al.   Frontiers in Neuroscience

The double life of autophagy proteins

(2018) Oliver Florey   Nature Microbiology

Inhibiting reactive oxygen species-dependent autophagy enhanced baicalein-induced apoptosis in oral squamous cell carcinoma

(2017) Bo Li et al.   Journal of Natural Medicines

NLRP3 Inflammasome Activation-Mediated Pyroptosis Aggravates Myocardial Ischemia/Reperfusion Injury in Diabetic Rats

(2017) Zhen Qiu et al.   Oxidative Medicine and Cellular Longevity

Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death

(2017) Jianjin Shi et al.   TRENDS IN BIOCHEMICAL SCIENCES

MiR-155 is Involved in Renal Ischemia-Reperfusion Injury via Direct Targeting of FoxO3a and Regulating Renal Tubular Cell Pyroptosis

(2016) Haoyu Wu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Acanthopanaxversus3-Methyladenine Ameliorates Sodium Taurocholate-Induced Severe Acute Pancreatitis by Inhibiting the Autophagic Pathway in Rats

(2016) Xiaohong Wang et al.   MEDIATORS OF INFLAMMATION

Baicalein pretreatment reduces liver ischemia/reperfusion injury via induction of autophagy in rats

(2016) Anding Liu et al.   Scientific Reports

The Role of Endoplasmic Reticulum Stress in Human Pathology

(2015) Scott A. Oakes et al.   Annual Review of Pathology-Mechanisms of Disease

Cell death induced by endoplasmic reticulum stress

(2015) Raffaella Iurlaro et al.   FEBS Journal

Baicalein pretreatment protects against liver ischemia/reperfusion injury via inhibition of NF-κB pathway in mice

(2015) Anding Liu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Silver Nanoparticles Induce Degradation of the Endoplasmic Reticulum Stress Sensor Activating Transcription Factor-6 Leading to Activation of the NLRP-3 Inflammasome

(2015) Jean-Christophe Simard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagic neuron death in neonatal brain ischemia/hypoxia

(2014) Yasuo Uchiyama et al.   Autophagy

Thioredoxin-interacting protein regulates protein disulfide isomerases and endoplasmic reticulum stress

(2014) S. Lee et al.   EMBO Molecular Medicine

Role of the TLR4 pathway in blood-spinal cord barrier dysfunction during the bimodal stage after ischemia/reperfusion injury in rats

(2014) Xiao-Qian Li et al.   Journal of Neuroinflammation

Mitochondria autophagy is induced after hypoxic/ischemic stress in a Drp1 dependent manner: The role of inhibition of Drp1 in ischemic brain damage

(2014) Wei Zuo et al.   NEUROPHARMACOLOGY

Endoplasmic reticulum stress is sufficient for the induction of IL-1β production via activation of the NF-κB and inflammasome pathways

(2013) Sena Kim et al.   Innate Immunity

Inflammasome Components Coordinate Autophagy and Pyroptosis as Macrophage Responses to Infection

(2013) B. G. Byrne et al.   mBio

Baicalein Protects against 6-OHDA-Induced Neurotoxicity through Activation of Keap1/Nrf2/HO-1 and Involving PKCα and PI3K/AKT Signaling Pathways

(2012) Zaijun Zhang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Regulation of inflammasome signaling

(2012) Vijay A K Rathinam et al.   NATURE IMMUNOLOGY

Baicalein protects against doxorubicin-induced cardiotoxicity by attenuation of mitochondrial oxidant injury and JNK activation

(2011) Wei-Tien Chang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Critical Care of Traumatic Spinal Cord Injury

(2011) Xiaofeng Jia et al.   JOURNAL OF INTENSIVE CARE MEDICINE

Baicalein protects HT22 murine hippocampal neuronal cells against endoplasmic reticulum stress-induced apoptosis through inhibition of reactive oxygen species production and CHOP induction

(2010) Ji Hyun Choi et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Sodium 4-phenylbutyrate protects against spinal cord ischemia by inhibition of endoplasmic reticulum stress

(2010) Taketomo Mizukami et al.   JOURNAL OF VASCULAR SURGERY

Spinal cord complications after thoracic aortic surgery: Long-term survival and functional status varies with deficit severity

(2008) Mark F. Conrad et al.   JOURNAL OF VASCULAR SURGERY